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Gene ID: 1471 | CST3 Antibody Resource


CST3 Antibody Resource
Gene Full Name: 
cystatin C
Uniprot: 
P01034
Protein Name: 
cystatin-C
Nucleotide: 
XM_005260672
Alias: 
ARMD11;
Ensembl: 
ENSG00000101439
Location: 
20p11.21
HPRD: 
05056
NCBI Gene: 
1471
MIM: 
604312

Summary: 
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. Alternative splicing results in multiple transcript variants encoding a single protein. [provided by RefSeq, Dec 2013]
Function: 
As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
Subcellular location: 
Secreted .
PTM: 
Disulfide bond;
Disease: 
Amyloidosis 6 (AMYL6) [MIM:105150]: A hereditary generalized amyloidosis due to cystatin C amyloid deposition. Cystatin C amyloid accumulates in the walls of arteries, arterioles, and sometimes capillaries and veins of the brain, and in various organs including lymphoid tissue, spleen, salivary glands, and seminal vesicles. Amyloid deposition in the cerebral vessels results in cerebral amyloid angiopathy, cerebral hemorrhage and premature stroke. Cystatin C levels in the cerebrospinal fluid are abnormally low. Note: The disease is caused by mutations affecting the gene represented in this entry. Macular degeneration, age-related, 11 (ARMD11) [MIM:611953]: A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Monoclonal Antibody OASA02655 CST3 Antibody (OASA02655) Human ELISA, IY 0.2mg $355 Details
Monoclonal Antibody OASA02656 CST3 Antibody (OASA02656) Human ELISA 0.2mg $365 Details
Monoclonal Antibody OASA02657 CST3 Antibody (OASA02657) Human ELISA, IY 0.2mg $365 Details
Monoclonal Antibody OAMA00961 MAb to Cystatin C Antibody (1mg) Human ELISA, IA 1mg $730 Details
Monoclonal Antibody OAMA00962 MAb to Cystatin C Antibody (1mg) Human ELISA 1mg $730 Details
Monoclonal Antibody OAMA00964 MAb to Cystatin C Antibody (1mg) Human ELISA, IA 1mg $740 Details
Monoclonal Antibody OAMA01016 MAb to Cystatin C Antibody (1mg) Human ELISA, IA 1mg $820 Details
Monoclonal Antibody OAMA01019 MAb to Cystatin C Antibody (1mg) Human ELISA, IA 1mg $740 Details
Monoclonal Antibody OAMA01020 MAb to Cystatin C Antibody (1mg) Human ELISA 1mg $730 Details
Monoclonal Antibody OAMA01021 MAb to Cystatin C Antibody (1mg) Human ELISA, IA 1mg $840 Details
Monoclonal Antibody OAMA01022 MAb to Cystatin C Antibody (1mg) Human ELISA, IA 1mg $730 Details
Protein OPMA04297 Cystatin C Free Serum Protein (50ml) 50ml $780 Details
Protein OPMA04539 Cystatin C Antigen Protein (1mg) ELISA 1mg $3180 Details
Protein OPSA11049 HUMAN CYSTATIN C Recombinant Protein (0.1mg) Human 0.1mg $925 Details
Polyclonal Antibody OAEB02184 Cst3 Antibody (OAEB02184) Mouse WB 0.1mg $289 Details
Polyclonal Antibody OAEB02281 Goat Anti-CST3 / cystatin C Antibody (OAEB02281) Human WB 0.1mg $289 Details
Polyclonal Antibody OAAB02288 CST3 antibody - C-terminal region (OAAB02288) Human WB, FC, IHC 400ul $289 Details
Polyclonal Antibody ARP44213_P050 CST3 Antibody (ARP44213_P050) Polyclonal Bovine, Guinea pig, Horse, Human, Mouse, Pig, Rat Not tested 50 ug $125 Details
Monoclonal Antibody OAAB07097 CST3 antibody (OAAB07097) Human WB 0.1 ml $289 Details
Polyclonal Antibody OAAB14292 Mouse Cst3 antibody - center region (OAAB14292) Mouse WB 400ul $289 Details
Polyclonal Antibody OAAF03541 CST3 Antibody (OAAF03541) Polyclonal Human, Mouse, Rat WB, ELISA 100 ug $229 Details

Show all CST3 antibodies


Product Images
CST3 antibody (OAAB07097) in 293 cells using Western Blot

Sample Type: 293

Mouse Cst3 antibody - center region (OAAB14292) in Mouse Spleen cells using Western Blot

Sample Type: Mouse Spleen

CST3 Antibody (OAAF03541) in COS-7 cells using Western Blot

Sample Type: COS-7

Cst3 Antibody (OAEB02184) in Mouse Testis cells using Western Blot

Sample Type: Mouse Testis

Goat Anti-CST3 / cystatin C Antibody (OAEB02281) in Human Testis cells using Western Blot

Sample Type: Human Testis


CST3 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP44213 Bovine CST3 antibody; Bos taurus CST3 antibody P01035 93.0%
ARP59195 Bovine CST3 antibody; Bos taurus CST3 antibody P01035 92.0%
ARP59195 Cat CST3 antibody; Felis catus CST3 antibody D5MTH1 92.0%
ARP44213 Cat CST3 antibody; Felis catus CST3 antibody D5MTH1 85.0%
ARP44213 Chimpanzee CST3 antibody; Pan troglodytes CST3 antibody K7AAK0 100.0%
ARP59195 Chimpanzee CST3 antibody; Pan troglodytes CST3 antibody K7AAK0 93.0%
ARP44213 Common squirrel monkey CST3 antibody; Saimiri sciureus CST3 antibody O19093 93.0%
ARP59195 Common squirrel monkey CST3 antibody; Saimiri sciureus CST3 antibody O19093 93.0%
ARP44213 Human CST3 antibody; Homo sapiens CST3 antibody P01034 100.0%
ARP59195 Human CST3 antibody; Homo sapiens CST3 antibody P01034 93.0%
ARP44213 Mouse CST3 antibody; Mus musculus CST3 antibody Q3U5K7 93.0%
ARP44213 Mouse CST3 antibody; Mus musculus CST3 antibody Q9EPX9 93.0%
ARP44213 Mouse CST3 antibody; Mus musculus CST3 antibody A2APX3 93.0%
ARP44213 Mouse CST3 antibody; Mus musculus CST3 antibody P21460 93.0%
ARP59195 Mouse CST3 antibody; Mus musculus CST3 antibody Q3U5K7 92.0%
ARP59195 Mouse CST3 antibody; Mus musculus CST3 antibody Q9EPX9 92.0%
ARP59195 Mouse CST3 antibody; Mus musculus CST3 antibody A2APX3 92.0%
ARP59195 Mouse CST3 antibody; Mus musculus CST3 antibody P21460 92.0%
ARP59195 Pig CST3 antibody; Sus scrofa CST3 antibody Q0Z8R0 93.0%
ARP44213 Pig CST3 antibody; Sus scrofa CST3 antibody Q0Z8R0 79.0%
ARP59195 Rabbit CST3 antibody; Oryctolagus cuniculus CST3 antibody G1SUE4 79.0%
ARP59195 Rabbit CST3 antibody; Oryctolagus cuniculus CST3 antibody O97862 79.0%
ARP59195 Rat CST3 antibody; Rattus norvegicus CST3 antibody P14841 86.0%
ARP44213 Rat CST3 antibody; Rattus norvegicus CST3 antibody P14841 79.0%
ARP44213 Rhesus macaque CST3 antibody; Macaca mulatta CST3 antibody O19092 100.0%
ARP59195 Rhesus macaque CST3 antibody; Macaca mulatta CST3 antibody O19092 93.0%
ARP59195 Sheep CST3 antibody; Ovis aries CST3 antibody K4P494 92.0%
ARP44213 Sheep CST3 antibody; Ovis aries CST3 antibody K4P494 86.0%
ARP44213 Sumatran orangutan CST3 antibody; Pongo abelii CST3 antibody H2P181 100.0%
ARP59195 Sumatran orangutan CST3 antibody; Pongo abelii CST3 antibody H2P181 93.0%
ARP44213 White-tufted-ear marmoset CST3 antibody; Callithrix jacchus CST3 antibody F6UCB8 93.0%
ARP59195 White-tufted-ear marmoset CST3 antibody; Callithrix jacchus CST3 antibody F6UCB8 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas201360_at721_B_lymphoblasts57.150811.310Details
BioGPS Gene Atlas201360_atAdipocyte2208.350811.310Details
BioGPS Gene Atlas201360_atAdrenalCortex220.350811.310Details
BioGPS Gene Atlas201360_atAdrenalgland286.700811.310Details
BioGPS Gene Atlas201360_atAmygdala3056.400811.310Details
BioGPS Gene Atlas201360_atAppendix398.800811.310Details
BioGPS Gene Atlas201360_atAtrioventricularNode148.650811.310Details
BioGPS Gene Atlas201360_atBDCA4+_DentriticCells1560.450811.310Details
BioGPS Gene Atlas201360_atBonemarrow38.650811.310Details
BioGPS Gene Atlas201360_atBronchialEpithelialCells180.200811.310Details
BioGPS Gene Atlas201360_atCD105+_Endothelial107.350811.310Details
BioGPS Gene Atlas201360_atCD14+_Monocytes2694.400811.310Details
BioGPS Gene Atlas201360_atCD19+_BCells(neg._sel.)48.250811.310Details
BioGPS Gene Atlas201360_atCD33+_Myeloid1678.750811.310Details
BioGPS Gene Atlas201360_atCD34+264.400811.310Details
BioGPS Gene Atlas201360_atCD4+_Tcells12.850811.310Details
BioGPS Gene Atlas201360_atCD56+_NKCells287.050811.310Details
BioGPS Gene Atlas201360_atCD71+_EarlyErythroid6.150811.310Details
BioGPS Gene Atlas201360_atCD8+_Tcells3.250811.310Details
BioGPS Gene Atlas201360_atCardiacMyocytes184.250811.310Details
BioGPS Gene Atlas201360_atCaudatenucleus1657.200811.310Details
BioGPS Gene Atlas201360_atCerebellum893.000811.310Details
BioGPS Gene Atlas201360_atCerebellumPeduncles1209.350811.310Details
BioGPS Gene Atlas201360_atCiliaryGanglion192.050811.310Details
BioGPS Gene Atlas201360_atCingulateCortex1765.850811.310Details
BioGPS Gene Atlas201360_atColorectaladenocarcinoma633.300811.310Details
BioGPS Gene Atlas201360_atDorsalRootGanglion223.550811.310Details
BioGPS Gene Atlas201360_atFetalThyroid380.250811.310Details
BioGPS Gene Atlas201360_atFetalbrain205.450811.310Details
BioGPS Gene Atlas201360_atFetalliver52.900811.310Details
BioGPS Gene Atlas201360_atFetallung154.950811.310Details
BioGPS Gene Atlas201360_atGlobusPallidus770.900811.310Details
BioGPS Gene Atlas201360_atHeart1258.250811.310Details
BioGPS Gene Atlas201360_atHypothalamus990.700811.310Details
BioGPS Gene Atlas201360_atKidney139.550811.310Details
BioGPS Gene Atlas201360_atLeukemia_chronicMyelogenousK-56236.300811.310Details
BioGPS Gene Atlas201360_atLeukemia_promyelocytic-HL-602.550811.310Details
BioGPS Gene Atlas201360_atLeukemialymphoblastic(MOLT-4)2.200811.310Details
BioGPS Gene Atlas201360_atLiver761.100811.310Details
BioGPS Gene Atlas201360_atLung2035.650811.310Details
BioGPS Gene Atlas201360_atLymphnode470.050811.310Details
BioGPS Gene Atlas201360_atLymphoma_burkitts(Daudi)3.750811.310Details
BioGPS Gene Atlas201360_atLymphoma_burkitts(Raji)2.700811.310Details
BioGPS Gene Atlas201360_atMedullaOblongata1514.300811.310Details
BioGPS Gene Atlas201360_atOccipitalLobe2158.550811.310Details
BioGPS Gene Atlas201360_atOlfactoryBulb957.100811.310Details
BioGPS Gene Atlas201360_atOvary143.000811.310Details
BioGPS Gene Atlas201360_atPancreas155.750811.310Details
BioGPS Gene Atlas201360_atPancreaticIslet341.100811.310Details
BioGPS Gene Atlas201360_atParietalLobe1533.600811.310Details
BioGPS Gene Atlas201360_atPituitary529.050811.310Details
BioGPS Gene Atlas201360_atPlacenta340.700811.310Details
BioGPS Gene Atlas201360_atPons873.100811.310Details
BioGPS Gene Atlas201360_atPrefrontalCortex2692.000811.310Details
BioGPS Gene Atlas201360_atProstate1228.900811.310Details
BioGPS Gene Atlas201360_atSalivarygland558.700811.310Details
BioGPS Gene Atlas201360_atSkeletalMuscle125.950811.310Details
BioGPS Gene Atlas201360_atSkin106.950811.310Details
BioGPS Gene Atlas201360_atSmoothMuscle194.900811.310Details
BioGPS Gene Atlas201360_atSpinalcord1862.350811.310Details
BioGPS Gene Atlas201360_atSubthalamicNucleus1236.000811.310Details
BioGPS Gene Atlas201360_atSuperiorCervicalGanglion136.650811.310Details
BioGPS Gene Atlas201360_atTemporalLobe1513.450811.310Details
BioGPS Gene Atlas201360_atTestis502.600811.310Details
BioGPS Gene Atlas201360_atTestisGermCell1672.700811.310Details
BioGPS Gene Atlas201360_atTestisIntersitial492.550811.310Details
BioGPS Gene Atlas201360_atTestisLeydigCell461.200811.310Details
BioGPS Gene Atlas201360_atTestisSeminiferousTubule724.050811.310Details
BioGPS Gene Atlas201360_atThalamus1744.800811.310Details
BioGPS Gene Atlas201360_atThymus452.000811.310Details
BioGPS Gene Atlas201360_atThyroid1276.250811.310Details
BioGPS Gene Atlas201360_atTongue266.100811.310Details
BioGPS Gene Atlas201360_atTonsil111.250811.310Details
BioGPS Gene Atlas201360_atTrachea447.350811.310Details
BioGPS Gene Atlas201360_atTrigeminalGanglion302.200811.310Details
BioGPS Gene Atlas201360_atUterus519.750811.310Details
BioGPS Gene Atlas201360_atUterusCorpus112.150811.310Details
BioGPS Gene Atlas201360_atWholeBlood748.100811.310Details
BioGPS Gene Atlas201360_atWholebrain2990.650811.310Details
BioGPS Gene Atlas201360_atcolon335.950811.310Details
BioGPS Gene Atlas201360_atpineal_day975.680811.310Details
BioGPS Gene Atlas201360_atpineal_night805.780811.310Details
BioGPS Gene Atlas201360_atretina3981.300811.310Details
BioGPS Gene Atlas201360_atsmall_intestine333.500811.310Details
BioGPS NCI60201360_at786309.217470.950Details
BioGPS NCI60201360_atA172683.236470.950Details
BioGPS NCI60201360_atA20476.132470.950Details
BioGPS NCI60201360_atA361789.723470.950Details
BioGPS NCI60201360_atA498350.346470.950Details
BioGPS NCI60201360_atA549623.396470.950Details
BioGPS NCI60201360_atACC3678.679470.950Details
BioGPS NCI60201360_atACHN652.102470.950Details
BioGPS NCI60201360_atALVA3178.024470.950Details
BioGPS NCI60201360_atCAKI1132.291470.950Details
BioGPS NCI60201360_atCCRT CEM4.332470.950Details
BioGPS NCI60201360_atCOLO2051738.417470.950Details
BioGPS NCI60201360_atDLD1636.326470.950Details
BioGPS NCI60201360_atDU145280.438470.950Details
BioGPS NCI60201360_atEKVX1059.924470.950Details
BioGPS NCI60201360_atGM13378.889470.950Details
BioGPS NCI60201360_atGM1600345.797470.950Details
BioGPS NCI60201360_atGM2313147.651470.950Details
BioGPS NCI60201360_atGM234546.576470.950Details
BioGPS NCI60201360_atGM2493127.726470.950Details
BioGPS NCI60201360_atGM97353.018470.950Details
BioGPS NCI60201360_atHCC2998354.491470.950Details
BioGPS NCI60201360_atHCT116258.813470.950Details
BioGPS NCI60201360_atHCT15207.201470.950Details
BioGPS NCI60201360_atHEK 293 T-rex106.237470.950Details
BioGPS NCI60201360_atHEK 293T113.163470.950Details
BioGPS NCI60201360_atHEK293229.682470.950Details
BioGPS NCI60201360_atHELA157.777470.950Details
BioGPS NCI60201360_atHEPG22143.790470.950Details
BioGPS NCI60201360_atHL603.305470.950Details
BioGPS NCI60201360_atHOP621350.355470.950Details
BioGPS NCI60201360_atHOP921121.996470.950Details
BioGPS NCI60201360_atHS578T601.165470.950Details
BioGPS NCI60201360_atHSG333.924470.950Details
BioGPS NCI60201360_atHT1080262.576470.950Details
BioGPS NCI60201360_atHT29226.875470.950Details
BioGPS NCI60201360_atIGROV11461.655470.950Details
BioGPS NCI60201360_atIOSE80284.634470.950Details
BioGPS NCI60201360_atJURKAT43.510470.950Details
BioGPS NCI60201360_atK56243.591470.950Details
BioGPS NCI60201360_atKM12354.755470.950Details
BioGPS NCI60201360_atLN18312.598470.950Details
BioGPS NCI60201360_atLNCAP603.668470.950Details
BioGPS NCI60201360_atLOX IMVI64.827470.950Details
BioGPS NCI60201360_atM14772.094470.950Details
BioGPS NCI60201360_atMALME 3M1053.036470.950Details
BioGPS NCI60201360_atMCF7620.371470.950Details
BioGPS NCI60201360_atMD MB231663.803470.950Details
BioGPS NCI60201360_atMDA MB435674.172470.950Details
BioGPS NCI60201360_atMOLT43.119470.950Details
BioGPS NCI60201360_atNCI 460480.236470.950Details
BioGPS NCI60201360_atNCI H22695.915470.950Details
BioGPS NCI60201360_atNCI H23434.368470.950Details
BioGPS NCI60201360_atNCI H322M255.822470.950Details
BioGPS NCI60201360_atNCVADR RES100.356470.950Details
BioGPS NCI60201360_atOVCAR3468.298470.950Details
BioGPS NCI60201360_atOVCAR476.741470.950Details
BioGPS NCI60201360_atOVCAR5680.104470.950Details
BioGPS NCI60201360_atOVCAR8124.178470.950Details
BioGPS NCI60201360_atPANC1410.236470.950Details
BioGPS NCI60201360_atRL73.113470.950Details
BioGPS NCI60201360_atRPMI 822666.986470.950Details
BioGPS NCI60201360_atRS118463.167470.950Details
BioGPS NCI60201360_atRXF393790.256470.950Details
BioGPS NCI60201360_atSAOS2305.413470.950Details
BioGPS NCI60201360_atSF268645.850470.950Details
BioGPS NCI60201360_atSF295613.197470.950Details
BioGPS NCI60201360_atSF539434.393470.950Details
BioGPS NCI60201360_atSHSYSY+RA87.273470.950Details
BioGPS NCI60201360_atSHSYSY-RA76.719470.950Details
BioGPS NCI60201360_atSKMEL2726.693470.950Details
BioGPS NCI60201360_atSKMEL281528.828470.950Details
BioGPS NCI60201360_atSKMEL5992.953470.950Details
BioGPS NCI60201360_atSKOV3573.299470.950Details
BioGPS NCI60201360_atSN12C320.263470.950Details
BioGPS NCI60201360_atSNB19554.261470.950Details
BioGPS NCI60201360_atSNB75767.021470.950Details
BioGPS NCI60201360_atSR364.478470.950Details
BioGPS NCI60201360_atSW620404.267470.950Details
BioGPS NCI60201360_atT24637.356470.950Details
BioGPS NCI60201360_atT3M4338.862470.950Details
BioGPS NCI60201360_atTK10300.800470.950Details
BioGPS NCI60201360_atU1181172.653470.950Details
BioGPS NCI60201360_atU1381201.761470.950Details
BioGPS NCI60201360_atU20S96.317470.950Details
BioGPS NCI60201360_atU251135.138470.950Details
BioGPS NCI60201360_atU87293.582470.950Details
BioGPS NCI60201360_atUACC257956.032470.950Details
BioGPS NCI60201360_atUACC621922.471470.950Details
BioGPS NCI60201360_atUO31689.460470.950Details
BioGPS NCI60201360_atZR75_1238.110470.950Details
BioGPS NCI60201360_atastrocytes404.232470.950Details
BioGPS NCI60201360_athuh-7533.015470.950Details