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Gene ID: 1427 | Crygs Antibody Resource


Crygs Antibody Resource
Gene Full Name: 
crystallin, gamma S
Uniprot: 
P22914
Protein Name: 
beta-crystallin S
Nucleotide: 
XM_005247128
Alias: 
CRYG8;CTRCT20;
Ensembl: 
Location: 
3q27.3
HPRD: 
00439
NCBI Gene: 
1427
MIM: 
123730

Summary: 
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. This gene encodes a protein initially considered to be a beta-crystallin but the encoded protein is monomeric and has greater sequence similarity to other gamma-crystallins. This gene encodes the most significant gamma-crystallin in adult eye lens tissue. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq, Jul 2008]
Function: 
Crystallins are the dominant structural components of the vertebrate eye lens.
Subcellular location: 
PTM: 
Acetylation;
Disease: 
Cataract 20, multiple types (CTRCT20) [MIM:116100]: An opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. CTRCT20 includes progressive polymorphic anterior, posterior, or peripheral cortical. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB00754 CRYGS antibody - C-terminal region (OAAB00754) Human; Mouse WB, ELISA 400ul $289 Details
Polyclonal Antibody ARP52379_P050 Crygs antibody - C-terminal region (ARP52379_P050) Rat; Human WB 50ug $289 Details
Polyclonal Antibody ARP52380_P050 Crygs antibody - C-terminal region (ARP52380_P050) Rat; Human WB 50ug $289 Details

Show all Crygs antibodies


Product Images
Crygs antibody - C-terminal region (ARP52379_P050) in Rat Stomach cells using Western Blot

Sample Type: Rat Stomach

Crygs antibody - C-terminal region (ARP52380_P050) in Rat Testis cells using Western Blot

Sample Type: Rat Testis

CRYGS antibody - C-terminal region (OAAB00754) in mouse spleen cells using Western Blot

Sample Type: mouse spleen


Crygs Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP52380 Bovine Crygs antibody; Bos taurus Crygs antibody P06504 100.0%
ARP59760 Bovine Crygs antibody; Bos taurus Crygs antibody P06504 100.0%
ARP52379 Bovine Crygs antibody; Bos taurus Crygs antibody P06504 93.0%
ARP52379 Cat Crygs antibody; Felis catus Crygs antibody M3WND7 100.0%
ARP52380 Cat Crygs antibody; Felis catus Crygs antibody M3WND7 100.0%
ARP59760 Cat Crygs antibody; Felis catus Crygs antibody M3WND7 100.0%
ARP59760 Chicken Crygs antibody; Gallus gallus Crygs antibody D0UYB8 100.0%
ARP52379 Chimpanzee Crygs antibody; Pan troglodytes Crygs antibody H2RCF8 100.0%
ARP52380 Chimpanzee Crygs antibody; Pan troglodytes Crygs antibody H2RCF8 100.0%
ARP59760 Chimpanzee Crygs antibody; Pan troglodytes Crygs antibody H2RCF8 100.0%
ARP52379 Chinese softshell turtle Crygs antibody; Pelodiscus sinensis Crygs antibody K7GI08 79.0%
ARP52380 Chinese softshell turtle Crygs antibody; Pelodiscus sinensis Crygs antibody K7GI08 79.0%
ARP52379 Chinese softshell turtle Crygs antibody; Pelodiscus sinensis Crygs antibody K7GI15 79.0%
ARP52380 Chinese softshell turtle Crygs antibody; Pelodiscus sinensis Crygs antibody K7GI15 79.0%
ARP52380 Collared flycatcher Crygs antibody; Ficedula albicollis Crygs antibody U3KG12 86.0%
ARP59760 Common carp Crygs antibody; Cyprinus carpio Crygs antibody P10112 100.0%
ARP52379 Common carp Crygs antibody; Cyprinus carpio Crygs antibody P10112 79.0%
ARP52379 Dog Crygs antibody; Canis familiaris Crygs antibody A2IBY7 100.0%
ARP52380 Dog Crygs antibody; Canis familiaris Crygs antibody A2IBY7 100.0%
ARP59760 Dog Crygs antibody; Canis familiaris Crygs antibody A2IBY7 100.0%
ARP52379 Dog Crygs antibody; Canis familiaris Crygs antibody F1PYH3 100.0%
ARP52380 Dog Crygs antibody; Canis familiaris Crygs antibody F1PYH3 100.0%
ARP59760 Dog Crygs antibody; Canis familiaris Crygs antibody F1PYH3 100.0%
ARP59760 Domestic duck Crygs antibody; Anas platyrhynchos Crygs antibody U3IDR0 100.0%
ARP52380 Domestic duck Crygs antibody; Anas platyrhynchos Crygs antibody U3IDR0 79.0%
ARP59760 Duckbill platypus Crygs antibody; Ornithorhynchus anatinus Crygs antibody F6SLN0 100.0%
ARP59760 Duckbill platypus Crygs antibody; Ornithorhynchus anatinus Crygs antibody F6SLN9 100.0%
ARP59760 Duckbill platypus Crygs antibody; Ornithorhynchus anatinus Crygs antibody F6SLP8 100.0%
ARP52379 Duckbill platypus Crygs antibody; Ornithorhynchus anatinus Crygs antibody F6SLN0 79.0%
ARP52380 Duckbill platypus Crygs antibody; Ornithorhynchus anatinus Crygs antibody F6SLN0 79.0%
ARP52379 Duckbill platypus Crygs antibody; Ornithorhynchus anatinus Crygs antibody F6SLN9 79.0%
ARP52380 Duckbill platypus Crygs antibody; Ornithorhynchus anatinus Crygs antibody F6SLN9 79.0%
ARP52379 Duckbill platypus Crygs antibody; Ornithorhynchus anatinus Crygs antibody F6SLP8 79.0%
ARP52380 Duckbill platypus Crygs antibody; Ornithorhynchus anatinus Crygs antibody F6SLP8 79.0%
ARP52379 European domestic ferret Crygs antibody; Mustela putorius furo Crygs antibody M3XVR4 100.0%
ARP52380 European domestic ferret Crygs antibody; Mustela putorius furo Crygs antibody M3XVR4 100.0%
ARP59760 European domestic ferret Crygs antibody; Mustela putorius furo Crygs antibody M3XVR4 100.0%
ARP52379 Giant panda Crygs antibody; Ailuropoda melanoleuca Crygs antibody G1L2Q3 100.0%
ARP52380 Giant panda Crygs antibody; Ailuropoda melanoleuca Crygs antibody G1L2Q3 100.0%
ARP59760 Giant panda Crygs antibody; Ailuropoda melanoleuca Crygs antibody G1L2Q3 100.0%
ARP52379 Gray short-tailed opossum Crygs antibody; Monodelphis domestica Crygs antibody F6ZK55 86.0%
ARP52380 Gray short-tailed opossum Crygs antibody; Monodelphis domestica Crygs antibody F6ZK55 79.0%
ARP52380 Green anole Crygs antibody; Anolis carolinensis Crygs antibody G1KIH1 79.0%
ARP52379 Guinea pig Crygs antibody; Cavia porcellus Crygs antibody Q06EY1 100.0%
ARP52380 Guinea pig Crygs antibody; Cavia porcellus Crygs antibody Q06EY1 100.0%
ARP59760 Guinea pig Crygs antibody; Cavia porcellus Crygs antibody Q06EY1 100.0%
ARP52380 Horse Crygs antibody; Equus caballus Crygs antibody F7DV62 100.0%
ARP59760 Horse Crygs antibody; Equus caballus Crygs antibody F7DV62 100.0%
ARP52379 Horse Crygs antibody; Equus caballus Crygs antibody F7DV62 93.0%
ARP52379 Human Crygs antibody; Homo sapiens Crygs antibody P22914 100.0%
ARP52380 Human Crygs antibody; Homo sapiens Crygs antibody P22914 100.0%
ARP59760 Human Crygs antibody; Homo sapiens Crygs antibody P22914 100.0%
ARP59760 Mouse Crygs antibody; Mus musculus Crygs antibody Q3UPY3 100.0%
ARP59760 Mouse Crygs antibody; Mus musculus Crygs antibody O35486 100.0%
ARP52379 Mouse Crygs antibody; Mus musculus Crygs antibody Q3UPY3 93.0%
ARP52380 Mouse Crygs antibody; Mus musculus Crygs antibody Q3UPY3 93.0%
ARP52379 Mouse Crygs antibody; Mus musculus Crygs antibody O35486 93.0%
ARP52380 Mouse Crygs antibody; Mus musculus Crygs antibody O35486 93.0%
ARP52379 Pig Crygs antibody; Sus scrofa Crygs antibody F2Z5R4 100.0%
ARP59760 Pig Crygs antibody; Sus scrofa Crygs antibody F2Z5R4 100.0%
ARP52380 Pig Crygs antibody; Sus scrofa Crygs antibody F2Z5R4 93.0%
ARP59760 Rabbit Crygs antibody; Oryctolagus cuniculus Crygs antibody A4L9I8 100.0%
ARP52379 Rabbit Crygs antibody; Oryctolagus cuniculus Crygs antibody A4L9I8 93.0%
ARP52380 Rabbit Crygs antibody; Oryctolagus cuniculus Crygs antibody A4L9I8 93.0%
ARP52380 Rat Crygs antibody; Rattus norvegicus Crygs antibody P0C5E9 100.0%
ARP52379 Rat Crygs antibody; Rattus norvegicus Crygs antibody P0C5E9 93.0%
ARP52380 Small-eared galago Crygs antibody; Otolemur garnettii Crygs antibody H0XRY8 93.0%
ARP52379 Small-eared galago Crygs antibody; Otolemur garnettii Crygs antibody H0XRY8 79.0%
ARP52379 Sumatran orangutan Crygs antibody; Pongo abelii Crygs antibody H2PC96 100.0%
ARP52380 Sumatran orangutan Crygs antibody; Pongo abelii Crygs antibody H2PC96 100.0%
ARP59760 Sumatran orangutan Crygs antibody; Pongo abelii Crygs antibody H2PC96 100.0%
ARP52379 Tasmanian devil Crygs antibody; Sarcophilus harrisii Crygs antibody G3W833 79.0%
ARP52380 Tasmanian devil Crygs antibody; Sarcophilus harrisii Crygs antibody G3W833 79.0%
ARP52379 Thirteen-lined ground squirrel Crygs antibody; Spermophilus tridecemlineatus Crygs antibody I3NG75 100.0%
ARP59760 Thirteen-lined ground squirrel Crygs antibody; Spermophilus tridecemlineatus Crygs antibody I3NG75 100.0%
ARP52380 Thirteen-lined ground squirrel Crygs antibody; Spermophilus tridecemlineatus Crygs antibody I3NG75 93.0%
ARP52379 Western gray kangaroo Crygs antibody; Macropus fuliginosus Crygs antibody Q5EF38 86.0%
ARP52380 Western gray kangaroo Crygs antibody; Macropus fuliginosus Crygs antibody Q5EF38 79.0%
ARP52379 White-tufted-ear marmoset Crygs antibody; Callithrix jacchus Crygs antibody F7HPE6 100.0%
ARP59760 White-tufted-ear marmoset Crygs antibody; Callithrix jacchus Crygs antibody F7HPE6 100.0%
ARP52380 White-tufted-ear marmoset Crygs antibody; Callithrix jacchus Crygs antibody F7HPE6 93.0%
ARP52380 Zebra finch Crygs antibody; Taeniopygia guttata Crygs antibody H0Z8W3 86.0%

Tissue & Cell Line Gene Expression Data