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Gene ID: 1421 | CRYGD Antibody Resource


CRYGD Antibody Resource
Gene Full Name: 
crystallin, gamma D
Uniprot: 
P07320
Protein Name: 
gamma-crystallin D
Nucleotide: 
NM_006891
Alias: 
CCP;PCC;CACA;CCA3;CRYG4;CTRCT4;cry-g-D;
Ensembl: 
ENSG00000118231
Location: 
2q33.3
HPRD: 
00436
NCBI Gene: 
1421
MIM: 
123690

Summary: 
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq, Jul 2008]
Function: 
Crystallins are the dominant structural components of the vertebrate eye lens.
Subcellular location: 
PTM: 
Oxidation;
Disease: 
Cataract 4, multiple types (CTRCT4) [MIM:115700]: An opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. CTRCT4 includes crystalline aculeiform, congenital cerulean and non-nuclear polymorphic cataracts, among others. Crystalline aculeiform cataract is characterized by fiberglass-like or needle-like crystals projecting in different directions, through or close to the axial region of the lens. Non-nuclear polymorphic cataract is a partial opacity with variable location between the fetal nucleus of the lens and the equator. The fetal nucleus is normal. The opacities are irregular and look similar to a bunch of grapes and may be present simultaneously in different lens layers. Congenital cerulean cataract is characterized by peripheral bluish and white opacifications organized in concentric layers with occasional central lesions arranged radially. The opacities are observed in the superficial layers of the fetal nucleus as well as the adult nucleus of the lens. Involvement is usually bilateral. Visual acuity is only mildly reduced in childhood. In adulthood, the opacifications may progress, making lens extraction necessary. Histologically the lesions are described as fusiform cavities between lens fibers which contain a deeply staining granular material. Although the lesions may take on various colors, a dull blue is the most common appearance and is responsible for the designation cerulean cataract. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP59760_P050 CRYGD Antibody (ARP59760_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details
Polyclonal Antibody OAAB14354 CRYGD antibody - center region (OAAB14354) Human WB 400ul $289 Details

Show all CRYGD antibodies


Product Images
CRYGD antibody - center region (OAAB14354) in K562 cells using Western Blot

Sample Type: K562


CRYGD Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP52387 African clawed frog CRYGD antibody; Xenopus laevis CRYGD antibody Q66KM8 79.0%
ARP52063 Bovine CRYGD antibody; Bos taurus CRYGD antibody P08209 86.0%
ARP65007 Bovine CRYGD antibody; Bos taurus CRYGD antibody P08209 86.0%
ARP52063 Bovine CRYGD antibody; Bos taurus CRYGD antibody F1MDK9 86.0%
ARP65007 Bovine CRYGD antibody; Bos taurus CRYGD antibody F1MDK9 86.0%
ARP59760 Bovine CRYGD antibody; Bos taurus CRYGD antibody P08209 85.0%
ARP59760 Bovine CRYGD antibody; Bos taurus CRYGD antibody F1MDK9 85.0%
ARP52387 Bovine CRYGD antibody; Bos taurus CRYGD antibody P08209 79.0%
ARP52388 Bovine CRYGD antibody; Bos taurus CRYGD antibody P08209 79.0%
ARP65008 Bovine CRYGD antibody; Bos taurus CRYGD antibody P08209 79.0%
ARP52387 Bovine CRYGD antibody; Bos taurus CRYGD antibody F1MDK9 79.0%
ARP52388 Bovine CRYGD antibody; Bos taurus CRYGD antibody F1MDK9 79.0%
ARP59760 Cat CRYGD antibody; Felis catus CRYGD antibody M3W1B7 92.0%
ARP59760 Cat CRYGD antibody; Felis catus CRYGD antibody M3X7P2 92.0%
ARP52387 Cat CRYGD antibody; Felis catus CRYGD antibody M3X7P2 91.0%
ARP65008 Cat CRYGD antibody; Felis catus CRYGD antibody M3W1B7 79.0%
ARP65007 Cat CRYGD antibody; Felis catus CRYGD antibody M3X7P2 79.0%
ARP65008 Cat CRYGD antibody; Felis catus CRYGD antibody M3X7P2 79.0%
ARP59760 Chimpanzee CRYGD antibody; Pan troglodytes CRYGD antibody H2QJB0 100.0%
ARP65008 Chimpanzee CRYGD antibody; Pan troglodytes CRYGD antibody H2QJB0 86.0%
ARP52063 Chimpanzee CRYGD antibody; Pan troglodytes CRYGD antibody H2QJB0 79.0%
ARP65007 Chimpanzee CRYGD antibody; Pan troglodytes CRYGD antibody H2QJB0 79.0%
ARP59760 Dog CRYGD antibody; Canis familiaris CRYGD antibody A9JPX7 92.0%
ARP65008 Dog CRYGD antibody; Canis familiaris CRYGD antibody A9JPX7 79.0%
ARP59760 European domestic ferret CRYGD antibody; Mustela putorius furo CRYGD antibody M3XN41 92.0%
ARP65008 European domestic ferret CRYGD antibody; Mustela putorius furo CRYGD antibody M3XN41 86.0%
ARP65007 European domestic ferret CRYGD antibody; Mustela putorius furo CRYGD antibody M3XN41 79.0%
ARP59760 Human CRYGD antibody; Homo sapiens CRYGD antibody P07320 100.0%
ARP65008 Human CRYGD antibody; Homo sapiens CRYGD antibody P07320 86.0%
ARP52063 Human CRYGD antibody; Homo sapiens CRYGD antibody P07320 79.0%
ARP65007 Human CRYGD antibody; Homo sapiens CRYGD antibody P07320 79.0%
ARP59760 Mouse CRYGD antibody; Mus musculus CRYGD antibody P04342 85.0%
ARP52063 Mouse CRYGD antibody; Mus musculus CRYGD antibody P04342 79.0%
ARP65008 Mouse CRYGD antibody; Mus musculus CRYGD antibody P04342 79.0%
ARP65008 Mouse CRYGD antibody; Mus musculus CRYGD antibody F7CUK9 79.0%
ARP59760 Rat CRYGD antibody; Rattus norvegicus CRYGD antibody P10067 85.0%
ARP52063 Rat CRYGD antibody; Rattus norvegicus CRYGD antibody P10067 79.0%
ARP65007 Rat CRYGD antibody; Rattus norvegicus CRYGD antibody P10067 79.0%
ARP65008 Rat CRYGD antibody; Rattus norvegicus CRYGD antibody P10067 79.0%
ARP65008 Rat CRYGD antibody; Rattus norvegicus CRYGD antibody D3ZR45 79.0%
ARP59760 Rhesus macaque CRYGD antibody; Macaca mulatta CRYGD antibody F6PWY4 92.0%
ARP52063 Rhesus macaque CRYGD antibody; Macaca mulatta CRYGD antibody F6PWY4 86.0%
ARP65008 Rhesus macaque CRYGD antibody; Macaca mulatta CRYGD antibody F6PWY4 86.0%
ARP65007 Rhesus macaque CRYGD antibody; Macaca mulatta CRYGD antibody F6PWY4 79.0%
ARP59760 Small-eared galago CRYGD antibody; Otolemur garnettii CRYGD antibody H0XMY4 92.0%
ARP52063 Small-eared galago CRYGD antibody; Otolemur garnettii CRYGD antibody H0XMY4 86.0%
ARP52387 Small-eared galago CRYGD antibody; Otolemur garnettii CRYGD antibody H0XMY4 86.0%
ARP65008 Small-eared galago CRYGD antibody; Otolemur garnettii CRYGD antibody H0XMY4 86.0%
ARP52063 Western gray kangaroo CRYGD antibody; Macropus fuliginosus CRYGD antibody Q5EF39 93.0%
ARP65007 Western gray kangaroo CRYGD antibody; Macropus fuliginosus CRYGD antibody Q5EF39 79.0%
ARP59760 White-tufted-ear marmoset CRYGD antibody; Callithrix jacchus CRYGD antibody F7I0U5 92.0%
ARP52063 White-tufted-ear marmoset CRYGD antibody; Callithrix jacchus CRYGD antibody F7I0U5 86.0%
ARP65008 White-tufted-ear marmoset CRYGD antibody; Callithrix jacchus CRYGD antibody F7I0U5 86.0%
ARP65007 White-tufted-ear marmoset CRYGD antibody; Callithrix jacchus CRYGD antibody F7I0U5 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas207532_at721_B_lymphoblasts23.40030.290Details
BioGPS Gene Atlas207532_atAdipocyte27.15030.290Details
BioGPS Gene Atlas207532_atAdrenalCortex55.75030.290Details
BioGPS Gene Atlas207532_atAdrenalgland27.75030.290Details
BioGPS Gene Atlas207532_atAmygdala25.75030.290Details
BioGPS Gene Atlas207532_atAppendix33.50030.290Details
BioGPS Gene Atlas207532_atAtrioventricularNode58.20030.290Details
BioGPS Gene Atlas207532_atBDCA4+_DentriticCells25.20030.290Details
BioGPS Gene Atlas207532_atBonemarrow26.95030.290Details
BioGPS Gene Atlas207532_atBronchialEpithelialCells23.75030.290Details
BioGPS Gene Atlas207532_atCD105+_Endothelial24.45030.290Details
BioGPS Gene Atlas207532_atCD14+_Monocytes27.05030.290Details
BioGPS Gene Atlas207532_atCD19+_BCells(neg._sel.)26.35030.290Details
BioGPS Gene Atlas207532_atCD33+_Myeloid32.15030.290Details
BioGPS Gene Atlas207532_atCD34+32.65030.290Details
BioGPS Gene Atlas207532_atCD4+_Tcells26.95030.290Details
BioGPS Gene Atlas207532_atCD56+_NKCells24.85030.290Details
BioGPS Gene Atlas207532_atCD71+_EarlyErythroid23.15030.290Details
BioGPS Gene Atlas207532_atCD8+_Tcells21.90030.290Details
BioGPS Gene Atlas207532_atCardiacMyocytes46.20030.290Details
BioGPS Gene Atlas207532_atCaudatenucleus24.45030.290Details
BioGPS Gene Atlas207532_atCerebellum25.80030.290Details
BioGPS Gene Atlas207532_atCerebellumPeduncles45.95030.290Details
BioGPS Gene Atlas207532_atCiliaryGanglion35.85030.290Details
BioGPS Gene Atlas207532_atCingulateCortex28.60030.290Details
BioGPS Gene Atlas207532_atColorectaladenocarcinoma25.85030.290Details
BioGPS Gene Atlas207532_atDorsalRootGanglion74.90030.290Details
BioGPS Gene Atlas207532_atFetalThyroid26.75030.290Details
BioGPS Gene Atlas207532_atFetalbrain34.20030.290Details
BioGPS Gene Atlas207532_atFetalliver22.30030.290Details
BioGPS Gene Atlas207532_atFetallung21.85030.290Details
BioGPS Gene Atlas207532_atGlobusPallidus33.25030.290Details
BioGPS Gene Atlas207532_atHeart34.50030.290Details
BioGPS Gene Atlas207532_atHypothalamus27.00030.290Details
BioGPS Gene Atlas207532_atKidney24.90030.290Details
BioGPS Gene Atlas207532_atLeukemia_chronicMyelogenousK-56229.30030.290Details
BioGPS Gene Atlas207532_atLeukemia_promyelocytic-HL-6025.50030.290Details
BioGPS Gene Atlas207532_atLeukemialymphoblastic(MOLT-4)24.70030.290Details
BioGPS Gene Atlas207532_atLiver38.15030.290Details
BioGPS Gene Atlas207532_atLung28.65030.290Details
BioGPS Gene Atlas207532_atLymphnode31.30030.290Details
BioGPS Gene Atlas207532_atLymphoma_burkitts(Daudi)51.40030.290Details
BioGPS Gene Atlas207532_atLymphoma_burkitts(Raji)41.45030.290Details
BioGPS Gene Atlas207532_atMedullaOblongata23.50030.290Details
BioGPS Gene Atlas207532_atOccipitalLobe24.25030.290Details
BioGPS Gene Atlas207532_atOlfactoryBulb20.70030.290Details
BioGPS Gene Atlas207532_atOvary31.60030.290Details
BioGPS Gene Atlas207532_atPancreas30.85030.290Details
BioGPS Gene Atlas207532_atPancreaticIslet28.90030.290Details
BioGPS Gene Atlas207532_atParietalLobe29.05030.290Details
BioGPS Gene Atlas207532_atPituitary30.45030.290Details
BioGPS Gene Atlas207532_atPlacenta23.10030.290Details
BioGPS Gene Atlas207532_atPons26.70030.290Details
BioGPS Gene Atlas207532_atPrefrontalCortex31.15030.290Details
BioGPS Gene Atlas207532_atProstate27.50030.290Details
BioGPS Gene Atlas207532_atSalivarygland25.30030.290Details
BioGPS Gene Atlas207532_atSkeletalMuscle53.25030.290Details
BioGPS Gene Atlas207532_atSkin34.05030.290Details
BioGPS Gene Atlas207532_atSmoothMuscle37.10030.290Details
BioGPS Gene Atlas207532_atSpinalcord28.80030.290Details
BioGPS Gene Atlas207532_atSubthalamicNucleus25.45030.290Details
BioGPS Gene Atlas207532_atSuperiorCervicalGanglion54.80030.290Details
BioGPS Gene Atlas207532_atTemporalLobe39.95030.290Details
BioGPS Gene Atlas207532_atTestis23.15030.290Details
BioGPS Gene Atlas207532_atTestisGermCell20.90030.290Details
BioGPS Gene Atlas207532_atTestisIntersitial23.25030.290Details
BioGPS Gene Atlas207532_atTestisLeydigCell29.20030.290Details
BioGPS Gene Atlas207532_atTestisSeminiferousTubule43.00030.290Details
BioGPS Gene Atlas207532_atThalamus31.50030.290Details
BioGPS Gene Atlas207532_atThymus19.80030.290Details
BioGPS Gene Atlas207532_atThyroid26.90030.290Details
BioGPS Gene Atlas207532_atTongue28.20030.290Details
BioGPS Gene Atlas207532_atTonsil26.75030.290Details
BioGPS Gene Atlas207532_atTrachea23.10030.290Details
BioGPS Gene Atlas207532_atTrigeminalGanglion27.35030.290Details
BioGPS Gene Atlas207532_atUterus19.20030.290Details
BioGPS Gene Atlas207532_atUterusCorpus27.10030.290Details
BioGPS Gene Atlas207532_atWholeBlood24.00030.290Details
BioGPS Gene Atlas207532_atWholebrain20.95030.290Details
BioGPS Gene Atlas207532_atcolon22.40030.290Details
BioGPS Gene Atlas207532_atpineal_day28.90030.290Details
BioGPS Gene Atlas207532_atpineal_night25.44030.290Details
BioGPS Gene Atlas207532_atretina36.67530.290Details
BioGPS Gene Atlas207532_atsmall_intestine23.75030.290Details
BioGPS NCI60207532_at7867.6708.610Details
BioGPS NCI60207532_atA1726.2378.610Details
BioGPS NCI60207532_atA20418.4338.610Details
BioGPS NCI60207532_atA3617.5858.610Details
BioGPS NCI60207532_atA4989.3458.610Details
BioGPS NCI60207532_atA5497.5608.610Details
BioGPS NCI60207532_atACC37.7498.610Details
BioGPS NCI60207532_atACHN6.6918.610Details
BioGPS NCI60207532_atALVA3110.8818.610Details
BioGPS NCI60207532_atCAKI17.6918.610Details
BioGPS NCI60207532_atCCRT CEM12.4438.610Details
BioGPS NCI60207532_atCOLO2057.5608.610Details
BioGPS NCI60207532_atDLD17.2488.610Details
BioGPS NCI60207532_atDU1457.2478.610Details
BioGPS NCI60207532_atEKVX6.8718.610Details
BioGPS NCI60207532_atGM1337.1578.610Details
BioGPS NCI60207532_atGM16007.4938.610Details
BioGPS NCI60207532_atGM23137.0108.610Details
BioGPS NCI60207532_atGM23456.6698.610Details
BioGPS NCI60207532_atGM24937.5108.610Details
BioGPS NCI60207532_atGM978.7248.610Details
BioGPS NCI60207532_atHCC29987.6218.610Details
BioGPS NCI60207532_atHCT1167.1978.610Details
BioGPS NCI60207532_atHCT155.4158.610Details
BioGPS NCI60207532_atHEK 293 T-rex14.5898.610Details
BioGPS NCI60207532_atHEK 293T12.0348.610Details
BioGPS NCI60207532_atHEK2937.4208.610Details
BioGPS NCI60207532_atHELA6.8928.610Details
BioGPS NCI60207532_atHEPG26.9558.610Details
BioGPS NCI60207532_atHL6033.9638.610Details
BioGPS NCI60207532_atHOP6212.1538.610Details
BioGPS NCI60207532_atHOP926.7958.610Details
BioGPS NCI60207532_atHS578T7.3308.610Details
BioGPS NCI60207532_atHSG5.8898.610Details
BioGPS NCI60207532_atHT10807.3118.610Details
BioGPS NCI60207532_atHT298.3038.610Details
BioGPS NCI60207532_atIGROV17.3208.610Details
BioGPS NCI60207532_atIOSE806.9338.610Details
BioGPS NCI60207532_atJURKAT7.4468.610Details
BioGPS NCI60207532_atK56211.9248.610Details
BioGPS NCI60207532_atKM127.9448.610Details
BioGPS NCI60207532_atLN185.9478.610Details
BioGPS NCI60207532_atLNCAP7.4948.610Details
BioGPS NCI60207532_atLOX IMVI7.4828.610Details
BioGPS NCI60207532_atM147.4538.610Details
BioGPS NCI60207532_atMALME 3M8.9048.610Details
BioGPS NCI60207532_atMCF76.3578.610Details
BioGPS NCI60207532_atMD MB2317.8008.610Details
BioGPS NCI60207532_atMDA MB43511.8928.610Details
BioGPS NCI60207532_atMOLT48.4338.610Details
BioGPS NCI60207532_atNCI 4607.8958.610Details
BioGPS NCI60207532_atNCI H2267.7568.610Details
BioGPS NCI60207532_atNCI H237.5928.610Details
BioGPS NCI60207532_atNCI H322M8.8708.610Details
BioGPS NCI60207532_atNCVADR RES6.9058.610Details
BioGPS NCI60207532_atOVCAR38.5808.610Details
BioGPS NCI60207532_atOVCAR413.7378.610Details
BioGPS NCI60207532_atOVCAR57.1298.610Details
BioGPS NCI60207532_atOVCAR86.5808.610Details
BioGPS NCI60207532_atPANC17.5958.610Details
BioGPS NCI60207532_atRL77.8938.610Details
BioGPS NCI60207532_atRPMI 82268.0218.610Details
BioGPS NCI60207532_atRS118469.6758.610Details
BioGPS NCI60207532_atRXF3937.4558.610Details
BioGPS NCI60207532_atSAOS27.5988.610Details
BioGPS NCI60207532_atSF2687.4458.610Details
BioGPS NCI60207532_atSF2957.0338.610Details
BioGPS NCI60207532_atSF53911.9788.610Details
BioGPS NCI60207532_atSHSYSY+RA7.1048.610Details
BioGPS NCI60207532_atSHSYSY-RA7.2938.610Details
BioGPS NCI60207532_atSKMEL27.4408.610Details
BioGPS NCI60207532_atSKMEL287.5128.610Details
BioGPS NCI60207532_atSKMEL56.7838.610Details
BioGPS NCI60207532_atSKOV37.8798.610Details
BioGPS NCI60207532_atSN12C6.7718.610Details
BioGPS NCI60207532_atSNB196.9218.610Details
BioGPS NCI60207532_atSNB7510.8058.610Details
BioGPS NCI60207532_atSR9.0688.610Details
BioGPS NCI60207532_atSW6208.3178.610Details
BioGPS NCI60207532_atT247.7138.610Details
BioGPS NCI60207532_atT3M47.9098.610Details
BioGPS NCI60207532_atTK107.4248.610Details
BioGPS NCI60207532_atU1186.4818.610Details
BioGPS NCI60207532_atU1386.2298.610Details
BioGPS NCI60207532_atU20S7.1798.610Details
BioGPS NCI60207532_atU25111.1938.610Details
BioGPS NCI60207532_atU876.6298.610Details
BioGPS NCI60207532_atUACC2577.0258.610Details
BioGPS NCI60207532_atUACC627.5618.610Details
BioGPS NCI60207532_atUO316.5228.610Details
BioGPS NCI60207532_atZR75_18.2648.610Details
BioGPS NCI60207532_atastrocytes7.4828.610Details
BioGPS NCI60207532_athuh-710.4758.610Details