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Gene ID: 1420 | CRYGC Antibody Resource


CRYGC Antibody Resource
Gene Full Name: 
crystallin, gamma C
Uniprot: 
P07315
Protein Name: 
gamma-crystallin C
Nucleotide: 
NM_020989
Alias: 
CCL;CRYG3;CTRCT2;
Ensembl: 
ENSG00000163254
Location: 
2q33.3
HPRD: 
00435
NCBI Gene: 
1420
MIM: 
123680

Summary: 
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq, Jul 2008]
Function: 
Crystallins are the dominant structural components of the vertebrate eye lens.
Subcellular location: 
PTM: 
Methylation;
Disease: 
Cataract 2, multiple types (CTRCT2) [MIM:604307]: An opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. CTRCT2 includes Coppock-like cataract, among others. Coppock-like cataract is a congenital pulverulent disk-like opacity involving the embryonic nucleus with many tiny white dots in the lamellar portion of the lens. It is usually bilateral and dominantly inherited. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP52388_P050 CRYGC antibody - middle region (ARP52388_P050) Polyclonal Pig, Rabbit, Rat WB 50ug $289 Details
Polyclonal Antibody ARP52387_P050 CRYGC Antibody (ARP52387_P050) Polyclonal Bovine, Dog, Guinea pig, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details

Show all CRYGC antibodies


Product Images
CRYGC antibody - middle region (ARP52388_P050) in Human OVCAR-3 cells using Western Blot

Sample Type: Human OVCAR-3


CRYGC Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP59760 Bovine CRYGC antibody; Bos taurus CRYGC antibody Q28088 91.0%
ARP65007 Bovine CRYGC antibody; Bos taurus CRYGC antibody Q28088 82.0%
ARP52387 Bovine CRYGC antibody; Bos taurus CRYGC antibody Q28088 79.0%
ARP52388 Bovine CRYGC antibody; Bos taurus CRYGC antibody Q28088 79.0%
ARP52387 Chimpanzee CRYGC antibody; Pan troglodytes CRYGC antibody H2QJB1 100.0%
ARP52388 Chimpanzee CRYGC antibody; Pan troglodytes CRYGC antibody H2QJB1 100.0%
ARP59760 Chimpanzee CRYGC antibody; Pan troglodytes CRYGC antibody H2QJB1 91.0%
ARP52063 Chimpanzee CRYGC antibody; Pan troglodytes CRYGC antibody H2QJB1 79.0%
ARP52388 Dog CRYGC antibody; Canis familiaris CRYGC antibody A3RLE2 93.0%
ARP52387 Dog CRYGC antibody; Canis familiaris CRYGC antibody A3RLE2 79.0%
ARP52388 European domestic ferret CRYGC antibody; Mustela putorius furo CRYGC antibody M3XN42 86.0%
ARP52387 European domestic ferret CRYGC antibody; Mustela putorius furo CRYGC antibody M3XN42 79.0%
ARP59760 Guinea pig CRYGC antibody; Cavia porcellus CRYGC antibody A3RLD9 91.0%
ARP52387 Guinea pig CRYGC antibody; Cavia porcellus CRYGC antibody A3RLD9 86.0%
ARP65008 Guinea pig CRYGC antibody; Cavia porcellus CRYGC antibody A3RLD9 79.0%
ARP52387 Human CRYGC antibody; Homo sapiens CRYGC antibody P07315 100.0%
ARP52388 Human CRYGC antibody; Homo sapiens CRYGC antibody P07315 100.0%
ARP59760 Human CRYGC antibody; Homo sapiens CRYGC antibody P07315 91.0%
ARP52063 Human CRYGC antibody; Homo sapiens CRYGC antibody P07315 79.0%
ARP59760 Mouse CRYGC antibody; Mus musculus CRYGC antibody Q61597 91.0%
ARP59760 Mouse CRYGC antibody; Mus musculus CRYGC antibody A3RLD4 91.0%
ARP59760 Mouse CRYGC antibody; Mus musculus CRYGC antibody A3RLD5 91.0%
ARP52387 Mouse CRYGC antibody; Mus musculus CRYGC antibody Q61597 86.0%
ARP52387 Mouse CRYGC antibody; Mus musculus CRYGC antibody A3RLD4 86.0%
ARP52387 Mouse CRYGC antibody; Mus musculus CRYGC antibody A3RLD5 86.0%
ARP59760 Rabbit CRYGC antibody; Oryctolagus cuniculus CRYGC antibody G1TU07 91.0%
ARP52387 Rabbit CRYGC antibody; Oryctolagus cuniculus CRYGC antibody G1TU07 86.0%
ARP52388 Rabbit CRYGC antibody; Oryctolagus cuniculus CRYGC antibody G1TU07 86.0%
ARP65008 Rabbit CRYGC antibody; Oryctolagus cuniculus CRYGC antibody G1TU07 79.0%
ARP59760 Rat CRYGC antibody; Rattus norvegicus CRYGC antibody P02529 91.0%
ARP52387 Rat CRYGC antibody; Rattus norvegicus CRYGC antibody F1LQX2 79.0%
ARP52387 Rat CRYGC antibody; Rattus norvegicus CRYGC antibody P02529 79.0%
ARP52388 Rat CRYGC antibody; Rattus norvegicus CRYGC antibody P02529 79.0%
ARP52387 Rhesus macaque CRYGC antibody; Macaca mulatta CRYGC antibody A3RLD8 100.0%
ARP52388 Rhesus macaque CRYGC antibody; Macaca mulatta CRYGC antibody A3RLD8 93.0%
ARP59760 Rhesus macaque CRYGC antibody; Macaca mulatta CRYGC antibody A3RLD8 91.0%
ARP52063 Rhesus macaque CRYGC antibody; Macaca mulatta CRYGC antibody A3RLD8 79.0%
ARP52387 Small-eared galago CRYGC antibody; Otolemur garnettii CRYGC antibody H0XC23 86.0%
ARP52388 Small-eared galago CRYGC antibody; Otolemur garnettii CRYGC antibody H0XC23 86.0%
ARP65008 Small-eared galago CRYGC antibody; Otolemur garnettii CRYGC antibody H0XC23 85.0%
ARP52387 Sumatran orangutan CRYGC antibody; Pongo abelii CRYGC antibody H2P8F7 100.0%
ARP52388 Sumatran orangutan CRYGC antibody; Pongo abelii CRYGC antibody H2P8F7 93.0%
ARP59760 Sumatran orangutan CRYGC antibody; Pongo abelii CRYGC antibody H2P8F7 91.0%
ARP52063 Sumatran orangutan CRYGC antibody; Pongo abelii CRYGC antibody H2P8F7 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas207531_at721_B_lymphoblasts7.6506.810Details
BioGPS Gene Atlas207531_atAdipocyte6.5006.810Details
BioGPS Gene Atlas207531_atAdrenalCortex7.1506.810Details
BioGPS Gene Atlas207531_atAdrenalgland5.9006.810Details
BioGPS Gene Atlas207531_atAmygdala6.7506.810Details
BioGPS Gene Atlas207531_atAppendix7.0506.810Details
BioGPS Gene Atlas207531_atAtrioventricularNode5.9006.810Details
BioGPS Gene Atlas207531_atBDCA4+_DentriticCells6.9006.810Details
BioGPS Gene Atlas207531_atBonemarrow7.0506.810Details
BioGPS Gene Atlas207531_atBronchialEpithelialCells6.3006.810Details
BioGPS Gene Atlas207531_atCD105+_Endothelial6.6006.810Details
BioGPS Gene Atlas207531_atCD14+_Monocytes6.9006.810Details
BioGPS Gene Atlas207531_atCD19+_BCells(neg._sel.)6.9006.810Details
BioGPS Gene Atlas207531_atCD33+_Myeloid8.1506.810Details
BioGPS Gene Atlas207531_atCD34+8.1006.810Details
BioGPS Gene Atlas207531_atCD4+_Tcells6.9506.810Details
BioGPS Gene Atlas207531_atCD56+_NKCells7.6006.810Details
BioGPS Gene Atlas207531_atCD71+_EarlyErythroid6.1506.810Details
BioGPS Gene Atlas207531_atCD8+_Tcells6.1006.810Details
BioGPS Gene Atlas207531_atCardiacMyocytes8.9506.810Details
BioGPS Gene Atlas207531_atCaudatenucleus5.9506.810Details
BioGPS Gene Atlas207531_atCerebellum5.4006.810Details
BioGPS Gene Atlas207531_atCerebellumPeduncles8.1506.810Details
BioGPS Gene Atlas207531_atCiliaryGanglion5.5506.810Details
BioGPS Gene Atlas207531_atCingulateCortex6.8006.810Details
BioGPS Gene Atlas207531_atColorectaladenocarcinoma6.5006.810Details
BioGPS Gene Atlas207531_atDorsalRootGanglion5.1506.810Details
BioGPS Gene Atlas207531_atFetalThyroid6.4006.810Details
BioGPS Gene Atlas207531_atFetalbrain6.5006.810Details
BioGPS Gene Atlas207531_atFetalliver5.9006.810Details
BioGPS Gene Atlas207531_atFetallung5.2506.810Details
BioGPS Gene Atlas207531_atGlobusPallidus6.9506.810Details
BioGPS Gene Atlas207531_atHeart9.1506.810Details
BioGPS Gene Atlas207531_atHypothalamus6.9506.810Details
BioGPS Gene Atlas207531_atKidney5.8006.810Details
BioGPS Gene Atlas207531_atLeukemia_chronicMyelogenousK-5625.9006.810Details
BioGPS Gene Atlas207531_atLeukemia_promyelocytic-HL-605.8006.810Details
BioGPS Gene Atlas207531_atLeukemialymphoblastic(MOLT-4)5.5506.810Details
BioGPS Gene Atlas207531_atLiver9.4006.810Details
BioGPS Gene Atlas207531_atLung7.1506.810Details
BioGPS Gene Atlas207531_atLymphnode5.5506.810Details
BioGPS Gene Atlas207531_atLymphoma_burkitts(Daudi)8.5506.810Details
BioGPS Gene Atlas207531_atLymphoma_burkitts(Raji)9.6506.810Details
BioGPS Gene Atlas207531_atMedullaOblongata6.0506.810Details
BioGPS Gene Atlas207531_atOccipitalLobe5.9006.810Details
BioGPS Gene Atlas207531_atOlfactoryBulb5.1506.810Details
BioGPS Gene Atlas207531_atOvary4.8006.810Details
BioGPS Gene Atlas207531_atPancreas5.5006.810Details
BioGPS Gene Atlas207531_atPancreaticIslet7.2006.810Details
BioGPS Gene Atlas207531_atParietalLobe7.3506.810Details
BioGPS Gene Atlas207531_atPituitary7.7506.810Details
BioGPS Gene Atlas207531_atPlacenta6.5006.810Details
BioGPS Gene Atlas207531_atPons6.6506.810Details
BioGPS Gene Atlas207531_atPrefrontalCortex8.0006.810Details
BioGPS Gene Atlas207531_atProstate7.5006.810Details
BioGPS Gene Atlas207531_atSalivarygland5.3006.810Details
BioGPS Gene Atlas207531_atSkeletalMuscle9.6506.810Details
BioGPS Gene Atlas207531_atSkin6.4006.810Details
BioGPS Gene Atlas207531_atSmoothMuscle7.4506.810Details
BioGPS Gene Atlas207531_atSpinalcord7.0506.810Details
BioGPS Gene Atlas207531_atSubthalamicNucleus6.1506.810Details
BioGPS Gene Atlas207531_atSuperiorCervicalGanglion9.6506.810Details
BioGPS Gene Atlas207531_atTemporalLobe6.4506.810Details
BioGPS Gene Atlas207531_atTestis5.6006.810Details
BioGPS Gene Atlas207531_atTestisGermCell5.3506.810Details
BioGPS Gene Atlas207531_atTestisIntersitial5.7006.810Details
BioGPS Gene Atlas207531_atTestisLeydigCell6.5006.810Details
BioGPS Gene Atlas207531_atTestisSeminiferousTubule5.6506.810Details
BioGPS Gene Atlas207531_atThalamus6.8006.810Details
BioGPS Gene Atlas207531_atThymus5.0506.810Details
BioGPS Gene Atlas207531_atThyroid8.0006.810Details
BioGPS Gene Atlas207531_atTongue7.0006.810Details
BioGPS Gene Atlas207531_atTonsil7.5506.810Details
BioGPS Gene Atlas207531_atTrachea5.5006.810Details
BioGPS Gene Atlas207531_atTrigeminalGanglion6.7506.810Details
BioGPS Gene Atlas207531_atUterus5.3006.810Details
BioGPS Gene Atlas207531_atUterusCorpus7.8006.810Details
BioGPS Gene Atlas207531_atWholeBlood7.1006.810Details
BioGPS Gene Atlas207531_atWholebrain5.4506.810Details
BioGPS Gene Atlas207531_atcolon6.6006.810Details
BioGPS Gene Atlas207531_atpineal_day8.0206.810Details
BioGPS Gene Atlas207531_atpineal_night7.8806.810Details
BioGPS Gene Atlas207531_atretina7.9256.810Details
BioGPS Gene Atlas207531_atsmall_intestine6.2506.810Details
BioGPS NCI60207531_at7866.8436.680Details
BioGPS NCI60207531_atA1726.2096.680Details
BioGPS NCI60207531_atA2046.6136.680Details
BioGPS NCI60207531_atA3616.7006.680Details
BioGPS NCI60207531_atA4986.5856.680Details
BioGPS NCI60207531_atA5496.7706.680Details
BioGPS NCI60207531_atACC37.0226.680Details
BioGPS NCI60207531_atACHN6.2166.680Details
BioGPS NCI60207531_atALVA317.1546.680Details
BioGPS NCI60207531_atCAKI16.9456.680Details
BioGPS NCI60207531_atCCRT CEM10.0286.680Details
BioGPS NCI60207531_atCOLO2056.6966.680Details
BioGPS NCI60207531_atDLD16.4976.680Details
BioGPS NCI60207531_atDU1456.3506.680Details
BioGPS NCI60207531_atEKVX6.1116.680Details
BioGPS NCI60207531_atGM1336.7936.680Details
BioGPS NCI60207531_atGM16006.9416.680Details
BioGPS NCI60207531_atGM23136.7336.680Details
BioGPS NCI60207531_atGM23456.6576.680Details
BioGPS NCI60207531_atGM24937.0476.680Details
BioGPS NCI60207531_atGM977.5116.680Details
BioGPS NCI60207531_atHCC29985.8966.680Details
BioGPS NCI60207531_atHCT1166.6206.680Details
BioGPS NCI60207531_atHCT155.9306.680Details
BioGPS NCI60207531_atHEK 293 T-rex7.1506.680Details
BioGPS NCI60207531_atHEK 293T6.5956.680Details
BioGPS NCI60207531_atHEK2936.6016.680Details
BioGPS NCI60207531_atHELA6.1736.680Details
BioGPS NCI60207531_atHEPG26.6016.680Details
BioGPS NCI60207531_atHL607.7006.680Details
BioGPS NCI60207531_atHOP626.6206.680Details
BioGPS NCI60207531_atHOP926.3306.680Details
BioGPS NCI60207531_atHS578T6.5126.680Details
BioGPS NCI60207531_atHSG6.4116.680Details
BioGPS NCI60207531_atHT10806.5546.680Details
BioGPS NCI60207531_atHT297.2096.680Details
BioGPS NCI60207531_atIGROV16.5536.680Details
BioGPS NCI60207531_atIOSE806.5656.680Details
BioGPS NCI60207531_atJURKAT6.5966.680Details
BioGPS NCI60207531_atK5627.9676.680Details
BioGPS NCI60207531_atKM126.9786.680Details
BioGPS NCI60207531_atLN186.1576.680Details
BioGPS NCI60207531_atLNCAP6.6316.680Details
BioGPS NCI60207531_atLOX IMVI6.5936.680Details
BioGPS NCI60207531_atM146.5216.680Details
BioGPS NCI60207531_atMALME 3M7.7146.680Details
BioGPS NCI60207531_atMCF76.3486.680Details
BioGPS NCI60207531_atMD MB2316.8546.680Details
BioGPS NCI60207531_atMDA MB4357.2286.680Details
BioGPS NCI60207531_atMOLT46.9116.680Details
BioGPS NCI60207531_atNCI 4606.9586.680Details
BioGPS NCI60207531_atNCI H2266.8256.680Details
BioGPS NCI60207531_atNCI H236.6206.680Details
BioGPS NCI60207531_atNCI H322M6.5916.680Details
BioGPS NCI60207531_atNCVADR RES6.1456.680Details
BioGPS NCI60207531_atOVCAR36.9946.680Details
BioGPS NCI60207531_atOVCAR46.5776.680Details
BioGPS NCI60207531_atOVCAR56.4556.680Details
BioGPS NCI60207531_atOVCAR85.8916.680Details
BioGPS NCI60207531_atPANC16.8866.680Details
BioGPS NCI60207531_atRL76.7696.680Details
BioGPS NCI60207531_atRPMI 82266.7586.680Details
BioGPS NCI60207531_atRS118467.0476.680Details
BioGPS NCI60207531_atRXF3936.5746.680Details
BioGPS NCI60207531_atSAOS26.7326.680Details
BioGPS NCI60207531_atSF2686.5936.680Details
BioGPS NCI60207531_atSF2956.4986.680Details
BioGPS NCI60207531_atSF5396.2016.680Details
BioGPS NCI60207531_atSHSYSY+RA6.4296.680Details
BioGPS NCI60207531_atSHSYSY-RA6.5436.680Details
BioGPS NCI60207531_atSKMEL26.5616.680Details
BioGPS NCI60207531_atSKMEL286.6306.680Details
BioGPS NCI60207531_atSKMEL56.3026.680Details
BioGPS NCI60207531_atSKOV36.8336.680Details
BioGPS NCI60207531_atSN12C6.5236.680Details
BioGPS NCI60207531_atSNB195.9486.680Details
BioGPS NCI60207531_atSNB756.5356.680Details
BioGPS NCI60207531_atSR6.7476.680Details
BioGPS NCI60207531_atSW6206.7316.680Details
BioGPS NCI60207531_atT246.8156.680Details
BioGPS NCI60207531_atT3M47.2966.680Details
BioGPS NCI60207531_atTK106.5906.680Details
BioGPS NCI60207531_atU1186.4036.680Details
BioGPS NCI60207531_atU1386.1526.680Details
BioGPS NCI60207531_atU20S6.4106.680Details
BioGPS NCI60207531_atU2516.4496.680Details
BioGPS NCI60207531_atU876.3596.680Details
BioGPS NCI60207531_atUACC2576.4336.680Details
BioGPS NCI60207531_atUACC626.7346.680Details
BioGPS NCI60207531_atUO316.3456.680Details
BioGPS NCI60207531_atZR75_17.2276.680Details
BioGPS NCI60207531_atastrocytes6.7116.680Details
BioGPS NCI60207531_athuh-76.8436.680Details