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Gene ID: 1417 | CRYBB3 Antibody Resource


CRYBB3 Antibody Resource
Gene Full Name: 
crystallin, beta B3
Uniprot: 
P26998
Protein Name: 
beta-crystallin B3
Nucleotide: 
NM_004076
Alias: 
CRYB3;CATCN2;CTRCT22;
Ensembl: 
ENSG00000100053
Location: 
22q11.23
HPRD: 
00431
NCBI Gene: 
1417
MIM: 
123630

Summary: 
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B2. Mutations in this gene result in cataract congenital nuclear autosomal recessive type 2. [provided by RefSeq, Feb 2013]
Function: 
Crystallins are the dominant structural components of the vertebrate eye lens.
Subcellular location: 
PTM: 
Acetylation;
Disease: 
Cataract 22 (CTRCT22) [MIM:609741]: An opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. CTRCT22 includes nuclear cataract among others. Nuclear cataracts affect the central nucleus of the eye, and are often not highly visually significant. The density of the opacities varies greatly from fine dots to a dense, white and chalk-like, central cataract. The condition is usually bilateral. Nuclear cataracts are often combined with opacified cortical fibers encircling the nuclear opacity, which are referred to as cortical riders. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP52026_P050 CRYBB3 antibody - middle region (ARP52026_P050) Polyclonal Dog, Guinea pig, Mouse, Rabbit, Sheep, Zebrafish WB 50ug $289 Details
Polyclonal Antibody ARP52025_P050 CRYBB3 Antibody (ARP52025_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep Not tested 50 ug $125 Details
Polyclonal Antibody OAAB14005 CRYBB3 antibody - C - terminal region (OAAB14005) Human WB 400ul $289 Details

Show all CRYBB3 antibodies


Product Images
CRYBB3 antibody - middle region (ARP52026_P050) in Human HT1080 cells using Western Blot

Sample Type: Human HT1080

CRYBB3 antibody - C - terminal region (OAAB14005) in K562 cells using Western Blot

Sample Type: K562


CRYBB3 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP52026 Bovine CRYBB3 antibody; Bos taurus CRYBB3 antibody P19141 93.0%
ARP52025 Bovine CRYBB3 antibody; Bos taurus CRYBB3 antibody P19141 86.0%
ARP52026 Cat CRYBB3 antibody; Felis catus CRYBB3 antibody M3WJG8 100.0%
ARP52061 Chicken CRYBB3 antibody; Gallus gallus CRYBB3 antibody P55165 79.0%
ARP52026 Chimpanzee CRYBB3 antibody; Pan troglodytes CRYBB3 antibody H2QLE3 100.0%
ARP52025 Chimpanzee CRYBB3 antibody; Pan troglodytes CRYBB3 antibody H2QLE3 93.0%
ARP52026 Chinese softshell turtle CRYBB3 antibody; Pelodiscus sinensis CRYBB3 antibody K7GC58 79.0%
ARP52061 Collared flycatcher CRYBB3 antibody; Ficedula albicollis CRYBB3 antibody U3K1V1 86.0%
ARP52025 Dog CRYBB3 antibody; Canis familiaris CRYBB3 antibody E2R7P2 100.0%
ARP52026 Dog CRYBB3 antibody; Canis familiaris CRYBB3 antibody E2R7P2 100.0%
ARP52026 Duckbill platypus CRYBB3 antibody; Ornithorhynchus anatinus CRYBB3 antibody F6Z4S4 86.0%
ARP52026 European domestic ferret CRYBB3 antibody; Mustela putorius furo CRYBB3 antibody M3YQH0 100.0%
ARP52025 European domestic ferret CRYBB3 antibody; Mustela putorius furo CRYBB3 antibody M3YQH0 93.0%
ARP52026 European seabass CRYBB3 antibody; Dicentrarchus labrax CRYBB3 antibody E6ZG41 79.0%
ARP52026 Giant panda CRYBB3 antibody; Ailuropoda melanoleuca CRYBB3 antibody G1MHV2 100.0%
ARP52025 Giant panda CRYBB3 antibody; Ailuropoda melanoleuca CRYBB3 antibody G1MHV2 86.0%
ARP52025 Gray short-tailed opossum CRYBB3 antibody; Monodelphis domestica CRYBB3 antibody F7AUT2 79.0%
ARP52025 Guinea pig CRYBB3 antibody; Cavia porcellus CRYBB3 antibody A4L9L5 100.0%
ARP52026 Guinea pig CRYBB3 antibody; Cavia porcellus CRYBB3 antibody A4L9L5 79.0%
ARP52026 Horse CRYBB3 antibody; Equus caballus CRYBB3 antibody F6V3E8 100.0%
ARP52025 Horse CRYBB3 antibody; Equus caballus CRYBB3 antibody F6V3E8 85.0%
ARP52025 Human CRYBB3 antibody; Homo sapiens CRYBB3 antibody P26998 100.0%
ARP52026 Human CRYBB3 antibody; Homo sapiens CRYBB3 antibody P26998 100.0%
ARP52025 Human CRYBB3 antibody; Homo sapiens CRYBB3 antibody B1AHR5 100.0%
ARP52025 Katanga lion CRYBB3 antibody; Panthera leo bleyenberghi CRYBB3 antibody C6GYW6 100.0%
ARP52026 Mouse CRYBB3 antibody; Mus musculus CRYBB3 antibody Q8BPQ8 100.0%
ARP52025 Mouse CRYBB3 antibody; Mus musculus CRYBB3 antibody Q9JJU9 100.0%
ARP52026 Mouse CRYBB3 antibody; Mus musculus CRYBB3 antibody Q9JJU9 100.0%
ARP52025 Mouse CRYBB3 antibody; Mus musculus CRYBB3 antibody D3YYW5 100.0%
ARP52025 Mouse CRYBB3 antibody; Mus musculus CRYBB3 antibody D3Z1U1 100.0%
ARP52025 Mouse CRYBB3 antibody; Mus musculus CRYBB3 antibody D3Z2L5 100.0%
ARP52025 Pig CRYBB3 antibody; Sus scrofa CRYBB3 antibody F2Z4Y7 93.0%
ARP52026 Pig CRYBB3 antibody; Sus scrofa CRYBB3 antibody F2Z4Y7 93.0%
ARP52026 Rabbit CRYBB3 antibody; Oryctolagus cuniculus CRYBB3 antibody G1SSH3 100.0%
ARP52025 Rabbit CRYBB3 antibody; Oryctolagus cuniculus CRYBB3 antibody G1SSH3 93.0%
ARP52026 Rat CRYBB3 antibody; Rattus norvegicus CRYBB3 antibody P02524 100.0%
ARP52025 Rat CRYBB3 antibody; Rattus norvegicus CRYBB3 antibody P02524 93.0%
ARP52025 Sheep CRYBB3 antibody; Ovis aries CRYBB3 antibody Q52NW3 93.0%
ARP52026 Sheep CRYBB3 antibody; Ovis aries CRYBB3 antibody Q52NW3 93.0%
ARP52025 Small-eared galago CRYBB3 antibody; Otolemur garnettii CRYBB3 antibody H0WN00 100.0%
ARP52026 Small-eared galago CRYBB3 antibody; Otolemur garnettii CRYBB3 antibody H0WN00 100.0%
ARP52026 Tasmanian devil CRYBB3 antibody; Sarcophilus harrisii CRYBB3 antibody G3VVW5 86.0%
ARP52025 Tasmanian devil CRYBB3 antibody; Sarcophilus harrisii CRYBB3 antibody G3VVW5 79.0%
ARP52025 Thirteen-lined ground squirrel CRYBB3 antibody; Spermophilus tridecemlineatus CRYBB3 antibody I3MIE4 100.0%
ARP52026 Thirteen-lined ground squirrel CRYBB3 antibody; Spermophilus tridecemlineatus CRYBB3 antibody I3MIE4 100.0%
ARP52026 White-tufted-ear marmoset CRYBB3 antibody; Callithrix jacchus CRYBB3 antibody F7IHF5 100.0%
ARP52025 White-tufted-ear marmoset CRYBB3 antibody; Callithrix jacchus CRYBB3 antibody F7IHF5 92.0%
ARP52026 Zebrafish CRYBB3 antibody; Danio rerio CRYBB3 antibody Q52JI3 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas207685_at721_B_lymphoblasts4.5003.680Details
BioGPS Gene Atlas207685_atAdipocyte3.6003.680Details
BioGPS Gene Atlas207685_atAdrenalCortex3.8003.680Details
BioGPS Gene Atlas207685_atAdrenalgland3.0503.680Details
BioGPS Gene Atlas207685_atAmygdala3.8003.680Details
BioGPS Gene Atlas207685_atAppendix3.7503.680Details
BioGPS Gene Atlas207685_atAtrioventricularNode2.8003.680Details
BioGPS Gene Atlas207685_atBDCA4+_DentriticCells4.1003.680Details
BioGPS Gene Atlas207685_atBonemarrow3.5503.680Details
BioGPS Gene Atlas207685_atBronchialEpithelialCells3.5503.680Details
BioGPS Gene Atlas207685_atCD105+_Endothelial3.7003.680Details
BioGPS Gene Atlas207685_atCD14+_Monocytes3.9003.680Details
BioGPS Gene Atlas207685_atCD19+_BCells(neg._sel.)3.9003.680Details
BioGPS Gene Atlas207685_atCD33+_Myeloid4.7003.680Details
BioGPS Gene Atlas207685_atCD34+5.9003.680Details
BioGPS Gene Atlas207685_atCD4+_Tcells3.9503.680Details
BioGPS Gene Atlas207685_atCD56+_NKCells4.3503.680Details
BioGPS Gene Atlas207685_atCD71+_EarlyErythroid3.4503.680Details
BioGPS Gene Atlas207685_atCD8+_Tcells3.5003.680Details
BioGPS Gene Atlas207685_atCardiacMyocytes4.5503.680Details
BioGPS Gene Atlas207685_atCaudatenucleus3.2503.680Details
BioGPS Gene Atlas207685_atCerebellum2.9503.680Details
BioGPS Gene Atlas207685_atCerebellumPeduncles4.1003.680Details
BioGPS Gene Atlas207685_atCiliaryGanglion2.6003.680Details
BioGPS Gene Atlas207685_atCingulateCortex3.7003.680Details
BioGPS Gene Atlas207685_atColorectaladenocarcinoma3.6503.680Details
BioGPS Gene Atlas207685_atDorsalRootGanglion2.8003.680Details
BioGPS Gene Atlas207685_atFetalThyroid3.5003.680Details
BioGPS Gene Atlas207685_atFetalbrain3.6503.680Details
BioGPS Gene Atlas207685_atFetalliver3.1503.680Details
BioGPS Gene Atlas207685_atFetallung3.0503.680Details
BioGPS Gene Atlas207685_atGlobusPallidus2.7003.680Details
BioGPS Gene Atlas207685_atHeart4.6503.680Details
BioGPS Gene Atlas207685_atHypothalamus3.9503.680Details
BioGPS Gene Atlas207685_atKidney2.9503.680Details
BioGPS Gene Atlas207685_atLeukemia_chronicMyelogenousK-5623.2503.680Details
BioGPS Gene Atlas207685_atLeukemia_promyelocytic-HL-603.2003.680Details
BioGPS Gene Atlas207685_atLeukemialymphoblastic(MOLT-4)2.9003.680Details
BioGPS Gene Atlas207685_atLiver4.7503.680Details
BioGPS Gene Atlas207685_atLung4.0003.680Details
BioGPS Gene Atlas207685_atLymphnode3.1503.680Details
BioGPS Gene Atlas207685_atLymphoma_burkitts(Daudi)4.6003.680Details
BioGPS Gene Atlas207685_atLymphoma_burkitts(Raji)5.0503.680Details
BioGPS Gene Atlas207685_atMedullaOblongata3.3503.680Details
BioGPS Gene Atlas207685_atOccipitalLobe3.2503.680Details
BioGPS Gene Atlas207685_atOlfactoryBulb2.8503.680Details
BioGPS Gene Atlas207685_atOvary2.4003.680Details
BioGPS Gene Atlas207685_atPancreas2.9003.680Details
BioGPS Gene Atlas207685_atPancreaticIslet3.9003.680Details
BioGPS Gene Atlas207685_atParietalLobe3.8003.680Details
BioGPS Gene Atlas207685_atPituitary4.2503.680Details
BioGPS Gene Atlas207685_atPlacenta3.7503.680Details
BioGPS Gene Atlas207685_atPons3.4503.680Details
BioGPS Gene Atlas207685_atPrefrontalCortex4.5003.680Details
BioGPS Gene Atlas207685_atProstate4.2503.680Details
BioGPS Gene Atlas207685_atSalivarygland2.9003.680Details
BioGPS Gene Atlas207685_atSkeletalMuscle4.2003.680Details
BioGPS Gene Atlas207685_atSkin2.8003.680Details
BioGPS Gene Atlas207685_atSmoothMuscle4.1503.680Details
BioGPS Gene Atlas207685_atSpinalcord3.9003.680Details
BioGPS Gene Atlas207685_atSubthalamicNucleus3.3003.680Details
BioGPS Gene Atlas207685_atSuperiorCervicalGanglion4.1003.680Details
BioGPS Gene Atlas207685_atTemporalLobe3.3003.680Details
BioGPS Gene Atlas207685_atTestis3.1003.680Details
BioGPS Gene Atlas207685_atTestisGermCell3.0003.680Details
BioGPS Gene Atlas207685_atTestisIntersitial3.0503.680Details
BioGPS Gene Atlas207685_atTestisLeydigCell3.5503.680Details
BioGPS Gene Atlas207685_atTestisSeminiferousTubule3.1003.680Details
BioGPS Gene Atlas207685_atThalamus3.7003.680Details
BioGPS Gene Atlas207685_atThymus2.9003.680Details
BioGPS Gene Atlas207685_atThyroid4.5503.680Details
BioGPS Gene Atlas207685_atTongue3.5503.680Details
BioGPS Gene Atlas207685_atTonsil3.5003.680Details
BioGPS Gene Atlas207685_atTrachea3.0003.680Details
BioGPS Gene Atlas207685_atTrigeminalGanglion3.6003.680Details
BioGPS Gene Atlas207685_atUterus2.9503.680Details
BioGPS Gene Atlas207685_atUterusCorpus3.2503.680Details
BioGPS Gene Atlas207685_atWholeBlood4.0003.680Details
BioGPS Gene Atlas207685_atWholebrain3.1003.680Details
BioGPS Gene Atlas207685_atcolon3.6003.680Details
BioGPS Gene Atlas207685_atpineal_day4.5403.680Details
BioGPS Gene Atlas207685_atpineal_night4.4803.680Details
BioGPS Gene Atlas207685_atretina4.3753.680Details
BioGPS Gene Atlas207685_atsmall_intestine3.5003.680Details
BioGPS NCI60207685_at7863.9023.810Details
BioGPS NCI60207685_atA1723.6553.810Details
BioGPS NCI60207685_atA2043.7633.810Details
BioGPS NCI60207685_atA3613.8313.810Details
BioGPS NCI60207685_atA4983.8083.810Details
BioGPS NCI60207685_atA5493.8663.810Details
BioGPS NCI60207685_atACC33.9573.810Details
BioGPS NCI60207685_atACHN3.6133.810Details
BioGPS NCI60207685_atALVA314.0073.810Details
BioGPS NCI60207685_atCAKI13.9253.810Details
BioGPS NCI60207685_atCCRT CEM4.3043.810Details
BioGPS NCI60207685_atCOLO2053.8233.810Details
BioGPS NCI60207685_atDLD13.7643.810Details
BioGPS NCI60207685_atDU1453.6943.810Details
BioGPS NCI60207685_atEKVX3.7313.810Details
BioGPS NCI60207685_atGM1333.8933.810Details
BioGPS NCI60207685_atGM16003.9243.810Details
BioGPS NCI60207685_atGM23133.8653.810Details
BioGPS NCI60207685_atGM23453.8103.810Details
BioGPS NCI60207685_atGM24933.9293.810Details
BioGPS NCI60207685_atGM974.1883.810Details
BioGPS NCI60207685_atHCC29983.5183.810Details
BioGPS NCI60207685_atHCT1163.7953.810Details
BioGPS NCI60207685_atHCT153.6343.810Details
BioGPS NCI60207685_atHEK 293 T-rex3.8613.810Details
BioGPS NCI60207685_atHEK 293T3.7883.810Details
BioGPS NCI60207685_atHEK2933.7773.810Details
BioGPS NCI60207685_atHELA3.6783.810Details
BioGPS NCI60207685_atHEPG23.7863.810Details
BioGPS NCI60207685_atHL603.8753.810Details
BioGPS NCI60207685_atHOP623.8073.810Details
BioGPS NCI60207685_atHOP923.7153.810Details
BioGPS NCI60207685_atHS578T3.7543.810Details
BioGPS NCI60207685_atHSG3.7253.810Details
BioGPS NCI60207685_atHT10803.7813.810Details
BioGPS NCI60207685_atHT294.0233.810Details
BioGPS NCI60207685_atIGROV13.7693.810Details
BioGPS NCI60207685_atIOSE803.7783.810Details
BioGPS NCI60207685_atJURKAT3.7913.810Details
BioGPS NCI60207685_atK5624.0153.810Details
BioGPS NCI60207685_atKM123.9443.810Details
BioGPS NCI60207685_atLN183.6203.810Details
BioGPS NCI60207685_atLNCAP3.7983.810Details
BioGPS NCI60207685_atLOX IMVI3.7923.810Details
BioGPS NCI60207685_atM143.7603.810Details
BioGPS NCI60207685_atMALME 3M4.0103.810Details
BioGPS NCI60207685_atMCF73.6963.810Details
BioGPS NCI60207685_atMD MB2313.8423.810Details
BioGPS NCI60207685_atMDA MB4354.0063.810Details
BioGPS NCI60207685_atMOLT43.8673.810Details
BioGPS NCI60207685_atNCI 4603.8873.810Details
BioGPS NCI60207685_atNCI H2263.8813.810Details
BioGPS NCI60207685_atNCI H233.7973.810Details
BioGPS NCI60207685_atNCI H322M3.8103.810Details
BioGPS NCI60207685_atNCVADR RES3.6623.810Details
BioGPS NCI60207685_atOVCAR33.9563.810Details
BioGPS NCI60207685_atOVCAR43.7873.810Details
BioGPS NCI60207685_atOVCAR53.7593.810Details
BioGPS NCI60207685_atOVCAR83.6073.810Details
BioGPS NCI60207685_atPANC13.8303.810Details
BioGPS NCI60207685_atRL73.8523.810Details
BioGPS NCI60207685_atRPMI 82263.8413.810Details
BioGPS NCI60207685_atRS118463.9653.810Details
BioGPS NCI60207685_atRXF3933.7793.810Details
BioGPS NCI60207685_atSAOS23.8443.810Details
BioGPS NCI60207685_atSF2683.8043.810Details
BioGPS NCI60207685_atSF2953.7493.810Details
BioGPS NCI60207685_atSF5393.6723.810Details
BioGPS NCI60207685_atSHSYSY+RA3.7153.810Details
BioGPS NCI60207685_atSHSYSY-RA3.7653.810Details
BioGPS NCI60207685_atSKMEL23.7893.810Details
BioGPS NCI60207685_atSKMEL283.8023.810Details
BioGPS NCI60207685_atSKMEL53.7253.810Details
BioGPS NCI60207685_atSKOV33.9213.810Details
BioGPS NCI60207685_atSN12C3.7733.810Details
BioGPS NCI60207685_atSNB193.6833.810Details
BioGPS NCI60207685_atSNB753.7893.810Details
BioGPS NCI60207685_atSR3.8463.810Details
BioGPS NCI60207685_atSW6203.8293.810Details
BioGPS NCI60207685_atT243.8953.810Details
BioGPS NCI60207685_atT3M43.9463.810Details
BioGPS NCI60207685_atTK103.7843.810Details
BioGPS NCI60207685_atU1183.7273.810Details
BioGPS NCI60207685_atU1383.6313.810Details
BioGPS NCI60207685_atU20S3.6963.810Details
BioGPS NCI60207685_atU2513.7653.810Details
BioGPS NCI60207685_atU873.7233.810Details
BioGPS NCI60207685_atUACC2573.7403.810Details
BioGPS NCI60207685_atUACC623.8363.810Details
BioGPS NCI60207685_atUO313.6983.810Details
BioGPS NCI60207685_atZR75_13.8903.810Details
BioGPS NCI60207685_atastrocytes3.8013.810Details
BioGPS NCI60207685_athuh-73.8943.810Details