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Gene ID: 8738 | CRADD Antibody Resource


CRADD Antibody Resource
Gene Full Name: 
CASP2 and RIPK1 domain containing adaptor with death domain
Uniprot: 
P78560
Protein Name: 
death domain-containing protein CRADD
Nucleotide: 
XM_005269211
Alias: 
MRT34;RAIDD;
Ensembl: 
ENSG00000169372
Location: 
12q21.33-q23.1
HPRD: 
04584
NCBI Gene: 
8738
MIM: 
603454

Summary: 
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. [provided by RefSeq, Jul 2008]
Function: 
Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
Subcellular location: 
Cytoplasm. Nucleus.
PTM: 
Disease: 
Mental retardation, autosomal recessive 34 (MRT34) [MIM:614499]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRT34 is a non-syndromic form. Affected individuals have mildly delayed development and significantly impaired cognitive function, precluding independent living and self-care. Speech is rudimentary, but articulate; autism is not present. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OASA08137 CRADD Antibody (OASA08137) Human WB 0.1mg $310 Details
Polyclonal Antibody OASA08138 CRADD Antibody (OASA08138) Human WB 50ug $220 Details
Polyclonal Antibody OASA08139 CRADD antibody - C-terminal region (OASA08139) Human WB 0.1mg $310 Details
Polyclonal Antibody OASA08140 CRADD antibody - C-terminal region (OASA08140) Human WB 50ug $220 Details
Protein OPPA01736 CRADD Human - Recombinant Human Caspase and RIP Adapter with Death Domain (5ug) 5ug $100 Details
Polyclonal Antibody ARP61653_P050 CRADD Antibody (ARP61653_P050) Polyclonal Dog, Guinea pig, Human, Mouse Not tested 50 ug $125 Details
Polyclonal Antibody OAAB14340 CRADD antibody - center region (OAAB14340) Human WB 400ul $289 Details

Show all CRADD antibodies


Product Images
CRADD antibody - center region (OAAB14340) in NCI-H292 cells using Western Blot

Sample Type: NCI-H292

CRADD Antibody (OASA08137) in HeLa (H) or K562 (K) cells using Western Blot

Sample Type: HeLa (H) or K562 (K)

CRADD Antibody (OASA08138) in HeLa (H) or K562 (K) cells using Western Blot

Sample Type: HeLa (H) or K562 (K)


CRADD Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP61654 Bovine CRADD antibody; Bos taurus CRADD antibody Q0II52 91.0%
ARP61654 Cat CRADD antibody; Felis catus CRADD antibody M3X5B1 79.0%
ARP61653 Chimpanzee CRADD antibody; Pan troglodytes CRADD antibody H2Q6M0 100.0%
ARP61654 Chimpanzee CRADD antibody; Pan troglodytes CRADD antibody H2Q6M0 100.0%
ARP61653 Dog CRADD antibody; Canis familiaris CRADD antibody J9P8P2 100.0%
ARP61654 Dog CRADD antibody; Canis familiaris CRADD antibody J9P8P2 79.0%
ARP61653 European domestic ferret CRADD antibody; Mustela putorius furo CRADD antibody M3Y7S0 93.0%
ARP61654 European domestic ferret CRADD antibody; Mustela putorius furo CRADD antibody M3Y7S0 79.0%
ARP61653 Giant panda CRADD antibody; Ailuropoda melanoleuca CRADD antibody G1LTB6 93.0%
ARP61653 Giant panda CRADD antibody; Ailuropoda melanoleuca CRADD antibody G1LTB9 93.0%
ARP61654 Giant panda CRADD antibody; Ailuropoda melanoleuca CRADD antibody G1LTB9 79.0%
ARP61653 Gray short-tailed opossum CRADD antibody; Monodelphis domestica CRADD antibody F7AYR8 92.0%
ARP61654 Horse CRADD antibody; Equus caballus CRADD antibody F7BRT5 91.0%
ARP61653 Human CRADD antibody; Homo sapiens CRADD antibody P78560 100.0%
ARP61654 Human CRADD antibody; Homo sapiens CRADD antibody P78560 100.0%
ARP61653 Human CRADD antibody; Homo sapiens CRADD antibody Q53XL1 100.0%
ARP61654 Human CRADD antibody; Homo sapiens CRADD antibody Q53XL1 100.0%
ARP61653 Human CRADD antibody; Homo sapiens CRADD antibody Q8IY43 100.0%
ARP61654 Human CRADD antibody; Homo sapiens CRADD antibody Q8IY43 100.0%
ARP61653 Human CRADD antibody; Homo sapiens CRADD antibody B5BU44 100.0%
ARP61654 Human CRADD antibody; Homo sapiens CRADD antibody B5BU44 100.0%
ARP61654 Human CRADD antibody; Homo sapiens CRADD antibody B7Z2Q5 100.0%
ARP61654 Human CRADD antibody; Homo sapiens CRADD antibody F5H7C2 100.0%
ARP61654 Human CRADD antibody; Homo sapiens CRADD antibody F8VV49 100.0%
ARP61654 Human CRADD antibody; Homo sapiens CRADD antibody F8VVY5 100.0%
ARP61653 Mouse CRADD antibody; Mus musculus CRADD antibody O88843 92.0%
ARP61653 Mouse CRADD antibody; Mus musculus CRADD antibody Q549T4 92.0%
ARP61653 Mouse CRADD antibody; Mus musculus CRADD antibody Q9QWR7 92.0%
ARP61654 Rabbit CRADD antibody; Oryctolagus cuniculus CRADD antibody G1SF24 79.0%
ARP61654 Rat CRADD antibody; Rattus norvegicus CRADD antibody D3ZB14 91.0%
ARP61653 Rhesus macaque CRADD antibody; Macaca mulatta CRADD antibody F7E329 93.0%
ARP61654 Rhesus macaque CRADD antibody; Macaca mulatta CRADD antibody F7E329 93.0%
ARP61653 Rhesus macaque CRADD antibody; Macaca mulatta CRADD antibody I0FHQ0 93.0%
ARP61654 Rhesus macaque CRADD antibody; Macaca mulatta CRADD antibody I0FHQ0 93.0%
ARP61653 Small-eared galago CRADD antibody; Otolemur garnettii CRADD antibody H0XRF8 79.0%
ARP61653 Sumatran orangutan CRADD antibody; Pongo abelii CRADD antibody Q5R6I4 100.0%
ARP61654 Sumatran orangutan CRADD antibody; Pongo abelii CRADD antibody Q5R6I4 100.0%
ARP61653 Tasmanian devil CRADD antibody; Sarcophilus harrisii CRADD antibody G3VLZ3 92.0%
ARP61653 Thirteen-lined ground squirrel CRADD antibody; Spermophilus tridecemlineatus CRADD antibody I3MJ95 93.0%
ARP61654 White-tufted-ear marmoset CRADD antibody; Callithrix jacchus CRADD antibody F6V4Y0 100.0%
ARP61654 White-tufted-ear marmoset CRADD antibody; Callithrix jacchus CRADD antibody F6Z7A2 100.0%
ARP61654 White-tufted-ear marmoset CRADD antibody; Callithrix jacchus CRADD antibody F7IH85 100.0%
ARP61653 White-tufted-ear marmoset CRADD antibody; Callithrix jacchus CRADD antibody F7IH85 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas209833_at721_B_lymphoblasts4.8505.170Details
BioGPS Gene Atlas209833_atAdipocyte4.1005.170Details
BioGPS Gene Atlas209833_atAdrenalCortex4.1505.170Details
BioGPS Gene Atlas209833_atAdrenalgland3.3505.170Details
BioGPS Gene Atlas209833_atAmygdala4.2005.170Details
BioGPS Gene Atlas209833_atAppendix5.1005.170Details
BioGPS Gene Atlas209833_atAtrioventricularNode7.1005.170Details
BioGPS Gene Atlas209833_atBDCA4+_DentriticCells8.8005.170Details
BioGPS Gene Atlas209833_atBonemarrow3.9005.170Details
BioGPS Gene Atlas209833_atBronchialEpithelialCells4.0005.170Details
BioGPS Gene Atlas209833_atCD105+_Endothelial13.5005.170Details
BioGPS Gene Atlas209833_atCD14+_Monocytes10.0005.170Details
BioGPS Gene Atlas209833_atCD19+_BCells(neg._sel.)5.6005.170Details
BioGPS Gene Atlas209833_atCD33+_Myeloid5.2005.170Details
BioGPS Gene Atlas209833_atCD34+10.6005.170Details
BioGPS Gene Atlas209833_atCD4+_Tcells4.2505.170Details
BioGPS Gene Atlas209833_atCD56+_NKCells8.0505.170Details
BioGPS Gene Atlas209833_atCD71+_EarlyErythroid26.4505.170Details
BioGPS Gene Atlas209833_atCD8+_Tcells3.9005.170Details
BioGPS Gene Atlas209833_atCardiacMyocytes4.9005.170Details
BioGPS Gene Atlas209833_atCaudatenucleus4.6505.170Details
BioGPS Gene Atlas209833_atCerebellum3.2505.170Details
BioGPS Gene Atlas209833_atCerebellumPeduncles4.5005.170Details
BioGPS Gene Atlas209833_atCiliaryGanglion2.8005.170Details
BioGPS Gene Atlas209833_atCingulateCortex4.0005.170Details
BioGPS Gene Atlas209833_atColorectaladenocarcinoma3.4005.170Details
BioGPS Gene Atlas209833_atDorsalRootGanglion3.0505.170Details
BioGPS Gene Atlas209833_atFetalThyroid3.8505.170Details
BioGPS Gene Atlas209833_atFetalbrain4.0005.170Details
BioGPS Gene Atlas209833_atFetalliver4.0005.170Details
BioGPS Gene Atlas209833_atFetallung3.2005.170Details
BioGPS Gene Atlas209833_atGlobusPallidus2.9005.170Details
BioGPS Gene Atlas209833_atHeart6.7505.170Details
BioGPS Gene Atlas209833_atHypothalamus4.6005.170Details
BioGPS Gene Atlas209833_atKidney3.8005.170Details
BioGPS Gene Atlas209833_atLeukemia_chronicMyelogenousK-56220.6505.170Details
BioGPS Gene Atlas209833_atLeukemia_promyelocytic-HL-603.7505.170Details
BioGPS Gene Atlas209833_atLeukemialymphoblastic(MOLT-4)3.3505.170Details
BioGPS Gene Atlas209833_atLiver5.1505.170Details
BioGPS Gene Atlas209833_atLung5.4005.170Details
BioGPS Gene Atlas209833_atLymphnode3.8505.170Details
BioGPS Gene Atlas209833_atLymphoma_burkitts(Daudi)7.3505.170Details
BioGPS Gene Atlas209833_atLymphoma_burkitts(Raji)5.5005.170Details
BioGPS Gene Atlas209833_atMedullaOblongata3.7005.170Details
BioGPS Gene Atlas209833_atOccipitalLobe3.6005.170Details
BioGPS Gene Atlas209833_atOlfactoryBulb3.2005.170Details
BioGPS Gene Atlas209833_atOvary2.8505.170Details
BioGPS Gene Atlas209833_atPancreas3.1005.170Details
BioGPS Gene Atlas209833_atPancreaticIslet4.9505.170Details
BioGPS Gene Atlas209833_atParietalLobe4.0505.170Details
BioGPS Gene Atlas209833_atPituitary6.0005.170Details
BioGPS Gene Atlas209833_atPlacenta4.3005.170Details
BioGPS Gene Atlas209833_atPons3.6505.170Details
BioGPS Gene Atlas209833_atPrefrontalCortex4.1505.170Details
BioGPS Gene Atlas209833_atProstate4.7005.170Details
BioGPS Gene Atlas209833_atSalivarygland3.1505.170Details
BioGPS Gene Atlas209833_atSkeletalMuscle4.5505.170Details
BioGPS Gene Atlas209833_atSkin3.1005.170Details
BioGPS Gene Atlas209833_atSmoothMuscle4.4505.170Details
BioGPS Gene Atlas209833_atSpinalcord4.7505.170Details
BioGPS Gene Atlas209833_atSubthalamicNucleus3.6505.170Details
BioGPS Gene Atlas209833_atSuperiorCervicalGanglion4.6505.170Details
BioGPS Gene Atlas209833_atTemporalLobe3.5005.170Details
BioGPS Gene Atlas209833_atTestis4.0005.170Details
BioGPS Gene Atlas209833_atTestisGermCell3.5005.170Details
BioGPS Gene Atlas209833_atTestisIntersitial10.3005.170Details
BioGPS Gene Atlas209833_atTestisLeydigCell4.3005.170Details
BioGPS Gene Atlas209833_atTestisSeminiferousTubule3.6505.170Details
BioGPS Gene Atlas209833_atThalamus4.0005.170Details
BioGPS Gene Atlas209833_atThymus3.1005.170Details
BioGPS Gene Atlas209833_atThyroid4.9505.170Details
BioGPS Gene Atlas209833_atTongue3.8505.170Details
BioGPS Gene Atlas209833_atTonsil3.8005.170Details
BioGPS Gene Atlas209833_atTrachea3.4005.170Details
BioGPS Gene Atlas209833_atTrigeminalGanglion3.8505.170Details
BioGPS Gene Atlas209833_atUterus4.1005.170Details
BioGPS Gene Atlas209833_atUterusCorpus5.0505.170Details
BioGPS Gene Atlas209833_atWholeBlood4.3005.170Details
BioGPS Gene Atlas209833_atWholebrain3.6505.170Details
BioGPS Gene Atlas209833_atcolon4.3505.170Details
BioGPS Gene Atlas209833_atpineal_day5.6405.170Details
BioGPS Gene Atlas209833_atpineal_night5.4205.170Details
BioGPS Gene Atlas209833_atretina5.6505.170Details
BioGPS Gene Atlas209833_atsmall_intestine5.7505.170Details
BioGPS NCI60209833_at78623.22531.820Details
BioGPS NCI60209833_atA17245.61131.820Details
BioGPS NCI60209833_atA20424.06331.820Details
BioGPS NCI60209833_atA36124.21231.820Details
BioGPS NCI60209833_atA49819.36331.820Details
BioGPS NCI60209833_atA54925.06531.820Details
BioGPS NCI60209833_atACC325.05731.820Details
BioGPS NCI60209833_atACHN23.82731.820Details
BioGPS NCI60209833_atALVA3125.16431.820Details
BioGPS NCI60209833_atCAKI140.92831.820Details
BioGPS NCI60209833_atCCRT CEM26.24831.820Details
BioGPS NCI60209833_atCOLO20524.71031.820Details
BioGPS NCI60209833_atDLD124.25231.820Details
BioGPS NCI60209833_atDU14523.58831.820Details
BioGPS NCI60209833_atEKVX24.28731.820Details
BioGPS NCI60209833_atGM13327.47031.820Details
BioGPS NCI60209833_atGM160025.54231.820Details
BioGPS NCI60209833_atGM231324.97231.820Details
BioGPS NCI60209833_atGM234524.86731.820Details
BioGPS NCI60209833_atGM249325.16531.820Details
BioGPS NCI60209833_atGM9751.88231.820Details
BioGPS NCI60209833_atHCC299827.62831.820Details
BioGPS NCI60209833_atHCT116106.08531.820Details
BioGPS NCI60209833_atHCT1531.83531.820Details
BioGPS NCI60209833_atHEK 293 T-rex28.11131.820Details
BioGPS NCI60209833_atHEK 293T24.56431.820Details
BioGPS NCI60209833_atHEK29323.21431.820Details
BioGPS NCI60209833_atHELA23.94131.820Details
BioGPS NCI60209833_atHEPG242.16831.820Details
BioGPS NCI60209833_atHL6032.65231.820Details
BioGPS NCI60209833_atHOP6224.81531.820Details
BioGPS NCI60209833_atHOP9223.98731.820Details
BioGPS NCI60209833_atHS578T24.12531.820Details
BioGPS NCI60209833_atHSG31.69531.820Details
BioGPS NCI60209833_atHT108036.05231.820Details
BioGPS NCI60209833_atHT2922.12131.820Details
BioGPS NCI60209833_atIGROV124.17231.820Details
BioGPS NCI60209833_atIOSE8024.88731.820Details
BioGPS NCI60209833_atJURKAT24.72131.820Details
BioGPS NCI60209833_atK56225.65031.820Details
BioGPS NCI60209833_atKM1225.53631.820Details
BioGPS NCI60209833_atLN1828.26431.820Details
BioGPS NCI60209833_atLNCAP82.13831.820Details
BioGPS NCI60209833_atLOX IMVI156.22731.820Details
BioGPS NCI60209833_atM1429.14131.820Details
BioGPS NCI60209833_atMALME 3M25.27331.820Details
BioGPS NCI60209833_atMCF723.81931.820Details
BioGPS NCI60209833_atMD MB23124.44331.820Details
BioGPS NCI60209833_atMDA MB43525.23631.820Details
BioGPS NCI60209833_atMOLT425.12631.820Details
BioGPS NCI60209833_atNCI 46026.80331.820Details
BioGPS NCI60209833_atNCI H22624.63831.820Details
BioGPS NCI60209833_atNCI H2321.53231.820Details
BioGPS NCI60209833_atNCI H322M24.43931.820Details
BioGPS NCI60209833_atNCVADR RES12.41931.820Details
BioGPS NCI60209833_atOVCAR325.38631.820Details
BioGPS NCI60209833_atOVCAR418.86731.820Details
BioGPS NCI60209833_atOVCAR518.81331.820Details
BioGPS NCI60209833_atOVCAR88.49131.820Details
BioGPS NCI60209833_atPANC124.57331.820Details
BioGPS NCI60209833_atRL725.07031.820Details
BioGPS NCI60209833_atRPMI 822625.19531.820Details
BioGPS NCI60209833_atRS1184625.38831.820Details
BioGPS NCI60209833_atRXF39321.37131.820Details
BioGPS NCI60209833_atSAOS225.07431.820Details
BioGPS NCI60209833_atSF26824.59931.820Details
BioGPS NCI60209833_atSF29526.66631.820Details
BioGPS NCI60209833_atSF53924.39331.820Details
BioGPS NCI60209833_atSHSYSY+RA41.23631.820Details
BioGPS NCI60209833_atSHSYSY-RA24.39331.820Details
BioGPS NCI60209833_atSKMEL273.70431.820Details
BioGPS NCI60209833_atSKMEL2824.34131.820Details
BioGPS NCI60209833_atSKMEL533.25431.820Details
BioGPS NCI60209833_atSKOV331.19331.820Details
BioGPS NCI60209833_atSN12C22.26631.820Details
BioGPS NCI60209833_atSNB1924.06931.820Details
BioGPS NCI60209833_atSNB7524.24631.820Details
BioGPS NCI60209833_atSR144.82131.820Details
BioGPS NCI60209833_atSW62033.23631.820Details
BioGPS NCI60209833_atT2425.06031.820Details
BioGPS NCI60209833_atT3M417.17831.820Details
BioGPS NCI60209833_atTK1024.53131.820Details
BioGPS NCI60209833_atU11824.41931.820Details
BioGPS NCI60209833_atU13854.50931.820Details
BioGPS NCI60209833_atU20S24.45631.820Details
BioGPS NCI60209833_atU25183.40231.820Details
BioGPS NCI60209833_atU8724.10031.820Details
BioGPS NCI60209833_atUACC25721.94931.820Details
BioGPS NCI60209833_atUACC6228.31131.820Details
BioGPS NCI60209833_atUO3123.87031.820Details
BioGPS NCI60209833_atZR75_125.14031.820Details
BioGPS NCI60209833_atastrocytes20.94431.820Details
BioGPS NCI60209833_athuh-723.93231.820Details