Search Antibody, Protein, and ELISA Kit Solutions


Gene ID: 10898 | CPSF4 Antibody Resource


CPSF4 Antibody Resource
Gene Full Name: 
cleavage and polyadenylation specific factor 4, 30kDa
Uniprot: 
O95639
Protein Name: 
cleavage and polyadenylation specificity factor subunit 4
Nucleotide: 
NM_006693
Alias: 
NAR;NEB1;CPSF30;
Ensembl: 
ENSG00000160917
Location: 
7q22.1
HPRD: 
04338
NCBI Gene: 
10898
MIM: 
603052

Summary: 
Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Function: 
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
Subcellular location: 
Nucleus.
PTM: 
Phosphoprotein;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP40675_P050 CPSF4 antibody - C-terminal region (ARP40675_P050) Polyclonal Bovine, Dog, Human, Mouse, Pig, Rat WB 50ug $289 Details
Polyclonal Antibody OAAB06214 CPSF4 antibody - center region (OAAB06214) Human WB, ELISA 400ul $289 Details

Show all CPSF4 antibodies


Product Images
CPSF4 antibody - C-terminal region (ARP40675_P050) in Human Jurkat cells using Western Blot

Sample Type: Human Jurkat

CPSF4 antibody - center region (OAAB06214) in Jurkat cells using Western Blot

Sample Type: Jurkat


CPSF4 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP40675 Bovine CPSF4 antibody; Bos taurus CPSF4 antibody O19137 93.0%
ARP40675 Cat CPSF4 antibody; Felis catus CPSF4 antibody M3WLW1 100.0%
ARP40675 Chicken CPSF4 antibody; Gallus gallus CPSF4 antibody E1BV31 79.0%
ARP40675 Chimpanzee CPSF4 antibody; Pan troglodytes CPSF4 antibody H2QV04 93.0%
ARP40675 Chimpanzee CPSF4 antibody; Pan troglodytes CPSF4 antibody K7DTE1 93.0%
ARP40675 Collared flycatcher CPSF4 antibody; Ficedula albicollis CPSF4 antibody U3KH95 79.0%
ARP40675 Dog CPSF4 antibody; Canis familiaris CPSF4 antibody E2RBK7 100.0%
ARP40675 Dog CPSF4 antibody; Canis familiaris CPSF4 antibody J9P398 100.0%
ARP40675 Domestic duck CPSF4 antibody; Anas platyrhynchos CPSF4 antibody U3IH73 79.0%
ARP40675 Duckbill platypus CPSF4 antibody; Ornithorhynchus anatinus CPSF4 antibody F6PXL2 79.0%
ARP40675 European domestic ferret CPSF4 antibody; Mustela putorius furo CPSF4 antibody M3YYJ5 100.0%
ARP40675 Giant panda CPSF4 antibody; Ailuropoda melanoleuca CPSF4 antibody G1LI40 100.0%
ARP40675 Gray short-tailed opossum CPSF4 antibody; Monodelphis domestica CPSF4 antibody F7FVV8 79.0%
ARP40675 Green anole CPSF4 antibody; Anolis carolinensis CPSF4 antibody H9GJF7 79.0%
ARP40675 Horse CPSF4 antibody; Equus caballus CPSF4 antibody F7DCT2 100.0%
ARP40675 Human CPSF4 antibody; Homo sapiens CPSF4 antibody B7Z7B0 100.0%
ARP40675 Human CPSF4 antibody; Homo sapiens CPSF4 antibody C9JEV9 100.0%
ARP40675 Human CPSF4 antibody; Homo sapiens CPSF4 antibody H7C419 100.0%
ARP40675 Human CPSF4 antibody; Homo sapiens CPSF4 antibody O95639-2 100.0%
ARP40675 Human CPSF4 antibody; Homo sapiens CPSF4 antibody O95639-3 100.0%
ARP40675 Human CPSF4 antibody; Homo sapiens CPSF4 antibody O95639 100.0%
ARP40675 Mouse CPSF4 antibody; Mus musculus CPSF4 antibody B2LVG5 100.0%
ARP40675 Mouse CPSF4 antibody; Mus musculus CPSF4 antibody B2LVG6 100.0%
ARP40675 Mouse CPSF4 antibody; Mus musculus CPSF4 antibody E0CXT7 100.0%
ARP40675 Mouse CPSF4 antibody; Mus musculus CPSF4 antibody Q8BQZ5 100.0%
ARP40675 Northern white-cheeked gibbon CPSF4 antibody; Nomascus leucogenys CPSF4 antibody G1RJR0 100.0%
ARP40675 Rabbit CPSF4 antibody; Oryctolagus cuniculus CPSF4 antibody G1SHJ8 93.0%
ARP40675 Rat CPSF4 antibody; Rattus norvegicus CPSF4 antibody Q5FVR7 100.0%
ARP40675 Rhesus macaque CPSF4 antibody; Macaca mulatta CPSF4 antibody F6QYI7 100.0%
ARP40675 Rhesus macaque CPSF4 antibody; Macaca mulatta CPSF4 antibody F7BI49 100.0%
ARP40675 Rhesus macaque CPSF4 antibody; Macaca mulatta CPSF4 antibody H9FP23 100.0%
ARP40675 Small-eared galago CPSF4 antibody; Otolemur garnettii CPSF4 antibody H0X3M7 100.0%
ARP40675 Sumatran orangutan CPSF4 antibody; Pongo abelii CPSF4 antibody H2PLJ0 93.0%
ARP40675 Tasmanian devil CPSF4 antibody; Sarcophilus harrisii CPSF4 antibody G3WDI8 79.0%
ARP40675 Thirteen-lined ground squirrel CPSF4 antibody; Spermophilus tridecemlineatus CPSF4 antibody I3LZ23 100.0%
ARP40675 White-tufted-ear marmoset CPSF4 antibody; Callithrix jacchus CPSF4 antibody U3BK11 100.0%
ARP40675 White-tufted-ear marmoset CPSF4 antibody; Callithrix jacchus CPSF4 antibody U3C1K3 100.0%
ARP40675 White-tufted-ear marmoset CPSF4 antibody; Callithrix jacchus CPSF4 antibody U3F879 100.0%
ARP40675 Zebra finch CPSF4 antibody; Taeniopygia guttata CPSF4 antibody H0ZB24 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas206688_s_at721_B_lymphoblasts87.95023.220Details
BioGPS Gene Atlas206688_s_atAdipocyte13.30023.220Details
BioGPS Gene Atlas206688_s_atAdrenalCortex12.30023.220Details
BioGPS Gene Atlas206688_s_atAdrenalgland10.05023.220Details
BioGPS Gene Atlas206688_s_atAmygdala14.40023.220Details
BioGPS Gene Atlas206688_s_atAppendix9.75023.220Details
BioGPS Gene Atlas206688_s_atAtrioventricularNode7.45023.220Details
BioGPS Gene Atlas206688_s_atBDCA4+_DentriticCells49.75023.220Details
BioGPS Gene Atlas206688_s_atBonemarrow11.55023.220Details
BioGPS Gene Atlas206688_s_atBronchialEpithelialCells13.40023.220Details
BioGPS Gene Atlas206688_s_atCD105+_Endothelial106.80023.220Details
BioGPS Gene Atlas206688_s_atCD14+_Monocytes30.85023.220Details
BioGPS Gene Atlas206688_s_atCD19+_BCells(neg._sel.)43.80023.220Details
BioGPS Gene Atlas206688_s_atCD33+_Myeloid28.95023.220Details
BioGPS Gene Atlas206688_s_atCD34+84.35023.220Details
BioGPS Gene Atlas206688_s_atCD4+_Tcells58.55023.220Details
BioGPS Gene Atlas206688_s_atCD56+_NKCells43.55023.220Details
BioGPS Gene Atlas206688_s_atCD71+_EarlyErythroid73.15023.220Details
BioGPS Gene Atlas206688_s_atCD8+_Tcells65.10023.220Details
BioGPS Gene Atlas206688_s_atCardiacMyocytes13.20023.220Details
BioGPS Gene Atlas206688_s_atCaudatenucleus11.35023.220Details
BioGPS Gene Atlas206688_s_atCerebellum9.40023.220Details
BioGPS Gene Atlas206688_s_atCerebellumPeduncles14.90023.220Details
BioGPS Gene Atlas206688_s_atCiliaryGanglion5.60023.220Details
BioGPS Gene Atlas206688_s_atCingulateCortex17.55023.220Details
BioGPS Gene Atlas206688_s_atColorectaladenocarcinoma63.30023.220Details
BioGPS Gene Atlas206688_s_atDorsalRootGanglion4.45023.220Details
BioGPS Gene Atlas206688_s_atFetalThyroid13.30023.220Details
BioGPS Gene Atlas206688_s_atFetalbrain14.00023.220Details
BioGPS Gene Atlas206688_s_atFetalliver8.35023.220Details
BioGPS Gene Atlas206688_s_atFetallung15.35023.220Details
BioGPS Gene Atlas206688_s_atGlobusPallidus9.60023.220Details
BioGPS Gene Atlas206688_s_atHeart32.80023.220Details
BioGPS Gene Atlas206688_s_atHypothalamus26.40023.220Details
BioGPS Gene Atlas206688_s_atKidney7.95023.220Details
BioGPS Gene Atlas206688_s_atLeukemia_chronicMyelogenousK-56231.10023.220Details
BioGPS Gene Atlas206688_s_atLeukemia_promyelocytic-HL-6029.70023.220Details
BioGPS Gene Atlas206688_s_atLeukemialymphoblastic(MOLT-4)78.15023.220Details
BioGPS Gene Atlas206688_s_atLiver21.25023.220Details
BioGPS Gene Atlas206688_s_atLung15.00023.220Details
BioGPS Gene Atlas206688_s_atLymphnode18.95023.220Details
BioGPS Gene Atlas206688_s_atLymphoma_burkitts(Daudi)64.75023.220Details
BioGPS Gene Atlas206688_s_atLymphoma_burkitts(Raji)50.20023.220Details
BioGPS Gene Atlas206688_s_atMedullaOblongata11.15023.220Details
BioGPS Gene Atlas206688_s_atOccipitalLobe10.85023.220Details
BioGPS Gene Atlas206688_s_atOlfactoryBulb9.40023.220Details
BioGPS Gene Atlas206688_s_atOvary7.15023.220Details
BioGPS Gene Atlas206688_s_atPancreas18.10023.220Details
BioGPS Gene Atlas206688_s_atPancreaticIslet25.55023.220Details
BioGPS Gene Atlas206688_s_atParietalLobe11.15023.220Details
BioGPS Gene Atlas206688_s_atPituitary15.25023.220Details
BioGPS Gene Atlas206688_s_atPlacenta17.10023.220Details
BioGPS Gene Atlas206688_s_atPons11.85023.220Details
BioGPS Gene Atlas206688_s_atPrefrontalCortex19.30023.220Details
BioGPS Gene Atlas206688_s_atProstate25.25023.220Details
BioGPS Gene Atlas206688_s_atSalivarygland7.60023.220Details
BioGPS Gene Atlas206688_s_atSkeletalMuscle7.70023.220Details
BioGPS Gene Atlas206688_s_atSkin5.50023.220Details
BioGPS Gene Atlas206688_s_atSmoothMuscle19.25023.220Details
BioGPS Gene Atlas206688_s_atSpinalcord16.05023.220Details
BioGPS Gene Atlas206688_s_atSubthalamicNucleus13.85023.220Details
BioGPS Gene Atlas206688_s_atSuperiorCervicalGanglion11.15023.220Details
BioGPS Gene Atlas206688_s_atTemporalLobe13.25023.220Details
BioGPS Gene Atlas206688_s_atTestis35.95023.220Details
BioGPS Gene Atlas206688_s_atTestisGermCell42.50023.220Details
BioGPS Gene Atlas206688_s_atTestisIntersitial12.10023.220Details
BioGPS Gene Atlas206688_s_atTestisLeydigCell10.70023.220Details
BioGPS Gene Atlas206688_s_atTestisSeminiferousTubule12.95023.220Details
BioGPS Gene Atlas206688_s_atThalamus18.80023.220Details
BioGPS Gene Atlas206688_s_atThymus17.90023.220Details
BioGPS Gene Atlas206688_s_atThyroid20.25023.220Details
BioGPS Gene Atlas206688_s_atTongue8.95023.220Details
BioGPS Gene Atlas206688_s_atTonsil13.20023.220Details
BioGPS Gene Atlas206688_s_atTrachea8.70023.220Details
BioGPS Gene Atlas206688_s_atTrigeminalGanglion30.60023.220Details
BioGPS Gene Atlas206688_s_atUterus10.05023.220Details
BioGPS Gene Atlas206688_s_atUterusCorpus12.20023.220Details
BioGPS Gene Atlas206688_s_atWholeBlood15.20023.220Details
BioGPS Gene Atlas206688_s_atWholebrain23.50023.220Details
BioGPS Gene Atlas206688_s_atcolon9.55023.220Details
BioGPS Gene Atlas206688_s_atpineal_day16.88023.220Details
BioGPS Gene Atlas206688_s_atpineal_night16.18023.220Details
BioGPS Gene Atlas206688_s_atretina15.62523.220Details
BioGPS Gene Atlas206688_s_atsmall_intestine8.70023.220Details
BioGPS NCI60206688_s_at786234.118256.340Details
BioGPS NCI60206688_s_atA172306.464256.340Details
BioGPS NCI60206688_s_atA204129.674256.340Details
BioGPS NCI60206688_s_atA361251.204256.340Details
BioGPS NCI60206688_s_atA498193.693256.340Details
BioGPS NCI60206688_s_atA549142.537256.340Details
BioGPS NCI60206688_s_atACC3342.882256.340Details
BioGPS NCI60206688_s_atACHN530.650256.340Details
BioGPS NCI60206688_s_atALVA31256.029256.340Details
BioGPS NCI60206688_s_atCAKI1116.729256.340Details
BioGPS NCI60206688_s_atCCRT CEM119.753256.340Details
BioGPS NCI60206688_s_atCOLO20587.155256.340Details
BioGPS NCI60206688_s_atDLD1316.079256.340Details
BioGPS NCI60206688_s_atDU145261.701256.340Details
BioGPS NCI60206688_s_atEKVX153.140256.340Details
BioGPS NCI60206688_s_atGM13331.251256.340Details
BioGPS NCI60206688_s_atGM1600162.127256.340Details
BioGPS NCI60206688_s_atGM2313124.062256.340Details
BioGPS NCI60206688_s_atGM2345188.866256.340Details
BioGPS NCI60206688_s_atGM2493122.422256.340Details
BioGPS NCI60206688_s_atGM97125.386256.340Details
BioGPS NCI60206688_s_atHCC2998278.978256.340Details
BioGPS NCI60206688_s_atHCT116403.784256.340Details
BioGPS NCI60206688_s_atHCT15188.754256.340Details
BioGPS NCI60206688_s_atHEK 293 T-rex247.333256.340Details
BioGPS NCI60206688_s_atHEK 293T397.421256.340Details
BioGPS NCI60206688_s_atHEK293286.736256.340Details
BioGPS NCI60206688_s_atHELA270.199256.340Details
BioGPS NCI60206688_s_atHEPG2204.596256.340Details
BioGPS NCI60206688_s_atHL60267.211256.340Details
BioGPS NCI60206688_s_atHOP62355.671256.340Details
BioGPS NCI60206688_s_atHOP92142.361256.340Details
BioGPS NCI60206688_s_atHS578T165.010256.340Details
BioGPS NCI60206688_s_atHSG183.618256.340Details
BioGPS NCI60206688_s_atHT1080361.813256.340Details
BioGPS NCI60206688_s_atHT29264.871256.340Details
BioGPS NCI60206688_s_atIGROV1230.386256.340Details
BioGPS NCI60206688_s_atIOSE80139.228256.340Details
BioGPS NCI60206688_s_atJURKAT351.201256.340Details
BioGPS NCI60206688_s_atK562244.498256.340Details
BioGPS NCI60206688_s_atKM12203.139256.340Details
BioGPS NCI60206688_s_atLN18533.246256.340Details
BioGPS NCI60206688_s_atLNCAP123.669256.340Details
BioGPS NCI60206688_s_atLOX IMVI269.457256.340Details
BioGPS NCI60206688_s_atM14257.615256.340Details
BioGPS NCI60206688_s_atMALME 3M231.812256.340Details
BioGPS NCI60206688_s_atMCF7418.521256.340Details
BioGPS NCI60206688_s_atMD MB231264.474256.340Details
BioGPS NCI60206688_s_atMDA MB435289.117256.340Details
BioGPS NCI60206688_s_atMOLT4656.057256.340Details
BioGPS NCI60206688_s_atNCI 460174.765256.340Details
BioGPS NCI60206688_s_atNCI H226221.881256.340Details
BioGPS NCI60206688_s_atNCI H23288.505256.340Details
BioGPS NCI60206688_s_atNCI H322M54.331256.340Details
BioGPS NCI60206688_s_atNCVADR RES93.431256.340Details
BioGPS NCI60206688_s_atOVCAR3177.340256.340Details
BioGPS NCI60206688_s_atOVCAR4477.762256.340Details
BioGPS NCI60206688_s_atOVCAR5168.862256.340Details
BioGPS NCI60206688_s_atOVCAR8259.668256.340Details
BioGPS NCI60206688_s_atPANC1181.577256.340Details
BioGPS NCI60206688_s_atRL7690.960256.340Details
BioGPS NCI60206688_s_atRPMI 8226208.438256.340Details
BioGPS NCI60206688_s_atRS11846658.586256.340Details
BioGPS NCI60206688_s_atRXF393157.408256.340Details
BioGPS NCI60206688_s_atSAOS2370.398256.340Details
BioGPS NCI60206688_s_atSF268353.234256.340Details
BioGPS NCI60206688_s_atSF295277.456256.340Details
BioGPS NCI60206688_s_atSF539179.886256.340Details
BioGPS NCI60206688_s_atSHSYSY+RA367.934256.340Details
BioGPS NCI60206688_s_atSHSYSY-RA511.978256.340Details
BioGPS NCI60206688_s_atSKMEL2236.809256.340Details
BioGPS NCI60206688_s_atSKMEL2894.330256.340Details
BioGPS NCI60206688_s_atSKMEL5310.894256.340Details
BioGPS NCI60206688_s_atSKOV332.122256.340Details
BioGPS NCI60206688_s_atSN12C148.466256.340Details
BioGPS NCI60206688_s_atSNB19218.738256.340Details
BioGPS NCI60206688_s_atSNB7598.594256.340Details
BioGPS NCI60206688_s_atSR299.044256.340Details
BioGPS NCI60206688_s_atSW620367.346256.340Details
BioGPS NCI60206688_s_atT24188.304256.340Details
BioGPS NCI60206688_s_atT3M4228.277256.340Details
BioGPS NCI60206688_s_atTK10313.730256.340Details
BioGPS NCI60206688_s_atU118170.121256.340Details
BioGPS NCI60206688_s_atU138238.385256.340Details
BioGPS NCI60206688_s_atU20S261.255256.340Details
BioGPS NCI60206688_s_atU251230.813256.340Details
BioGPS NCI60206688_s_atU87244.324256.340Details
BioGPS NCI60206688_s_atUACC257203.514256.340Details
BioGPS NCI60206688_s_atUACC62175.040256.340Details
BioGPS NCI60206688_s_atUO31345.382256.340Details
BioGPS NCI60206688_s_atZR75_197.908256.340Details
BioGPS NCI60206688_s_atastrocytes214.655256.340Details
BioGPS NCI60206688_s_athuh-7292.332256.340Details