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Gene ID: 1371 | CPOX Antibody Resource


CPOX Antibody Resource
Gene Full Name: 
coproporphyrinogen oxidase
Uniprot: 
P36551
Protein Name: 
coproporphyrinogen-III oxidase, mitochondrial
Nucleotide: 
XM_005247125
Alias: 
CPO;CPX;HCP;
Ensembl: 
ENSG00000080819
Location: 
3q12
HPRD: 
00417
NCBI Gene: 
1371
MIM: 
612732

Summary: 
The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).[provided by RefSeq, Oct 2009]
Function: 
Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III.
Subcellular location: 
Mitochondrion intermembrane space.
PTM: 
Acetylation;
Disease: 
Hereditary coproporphyria (HCP) [MIM:121300]: A form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. Hereditary coproporphyria is an acute hepatic porphyria characterized by skin photosensitivity, attacks of abdominal pain, neurological disturbances, and psychiatric symptoms. Most attacks are precipitated by drugs, alcohol, caloric deprivation, infections, or endocrine factors. Hereditary coproporphyria is biochemically characterized by overexcretion of coproporphyrin III in the urine and in the feces. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB06338 CPOX antibody - C-terminal region (OAAB06338) Human; Mouse WB, ELISA 400ul $289 Details
Polyclonal Antibody ARP64945_P050 CPOX Antibody (ARP64945_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAGA00375 CPOX antibody (OAGA00375) Polyclonal Human WB 100 ul $340 Details

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CPOX Protocols

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Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP64945 African elephant CPOX antibody; Loxodonta africana CPOX antibody G3SQY5 100.0%
ARP64945 Bovine CPOX antibody; Bos taurus CPOX antibody E1BKY9 93.0%
ARP64945 Cat CPOX antibody; Felis catus CPOX antibody M3WMP6 93.0%
ARP64945 Chicken CPOX antibody; Gallus gallus CPOX antibody F1NR99 92.0%
ARP64945 Chimpanzee CPOX antibody; Pan troglodytes CPOX antibody H2QMZ9 100.0%
ARP64945 Chimpanzee CPOX antibody; Pan troglodytes CPOX antibody K7AUE8 100.0%
ARP64945 Chinese softshell turtle CPOX antibody; Pelodiscus sinensis CPOX antibody K7F7M2 79.0%
ARP64945 Collared flycatcher CPOX antibody; Ficedula albicollis CPOX antibody U3JT99 79.0%
ARP64945 Dog CPOX antibody; Canis familiaris CPOX antibody F1PW12 93.0%
ARP64945 Duckbill platypus CPOX antibody; Ornithorhynchus anatinus CPOX antibody F6TJW1 86.0%
ARP64945 European domestic ferret CPOX antibody; Mustela putorius furo CPOX antibody M3YIL9 93.0%
ARP64945 Giant panda CPOX antibody; Ailuropoda melanoleuca CPOX antibody G1MAI7 93.0%
ARP64945 Gray short-tailed opossum CPOX antibody; Monodelphis domestica CPOX antibody F6XHE8 86.0%
ARP64945 Horse CPOX antibody; Equus caballus CPOX antibody F6X658 100.0%
ARP64945 Human CPOX antibody; Homo sapiens CPOX antibody P36551 100.0%
ARP64945 Mouse CPOX antibody; Mus musculus CPOX antibody P36552 93.0%
ARP64945 Northern white-cheeked gibbon CPOX antibody; Nomascus leucogenys CPOX antibody G1QP66 100.0%
ARP64945 Pig CPOX antibody; Sus scrofa CPOX antibody F1SK95 100.0%
ARP64945 Rabbit CPOX antibody; Oryctolagus cuniculus CPOX antibody G1SJZ8 100.0%
ARP64945 Rat CPOX antibody; Rattus norvegicus CPOX antibody Q3B7D0 93.0%
ARP64945 Rhesus macaque CPOX antibody; Macaca mulatta CPOX antibody F7GNW9 100.0%
ARP64945 Small-eared galago CPOX antibody; Otolemur garnettii CPOX antibody H0WQX8 100.0%
ARP64945 Sumatran orangutan CPOX antibody; Pongo abelii CPOX antibody H2P9X7 100.0%
ARP64945 Tasmanian devil CPOX antibody; Sarcophilus harrisii CPOX antibody G3VGJ4 86.0%
ARP64945 Tasmanian devil CPOX antibody; Sarcophilus harrisii CPOX antibody G3VGJ5 86.0%
ARP64945 Thirteen-lined ground squirrel CPOX antibody; Spermophilus tridecemlineatus CPOX antibody I3MFN0 100.0%
ARP64945 White-tufted-ear marmoset CPOX antibody; Callithrix jacchus CPOX antibody F6ULT5 100.0%
ARP64945 White-tufted-ear marmoset CPOX antibody; Callithrix jacchus CPOX antibody F6VJV7 100.0%
ARP64945 Zebra finch CPOX antibody; Taeniopygia guttata CPOX antibody H0ZT91 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas204172_at721_B_lymphoblasts232.90035.280Details
BioGPS Gene Atlas204172_atAdipocyte10.35035.280Details
BioGPS Gene Atlas204172_atAdrenalCortex13.65035.280Details
BioGPS Gene Atlas204172_atAdrenalgland10.10035.280Details
BioGPS Gene Atlas204172_atAmygdala33.90035.280Details
BioGPS Gene Atlas204172_atAppendix12.95035.280Details
BioGPS Gene Atlas204172_atAtrioventricularNode11.10035.280Details
BioGPS Gene Atlas204172_atBDCA4+_DentriticCells9.70035.280Details
BioGPS Gene Atlas204172_atBonemarrow135.75035.280Details
BioGPS Gene Atlas204172_atBronchialEpithelialCells47.00035.280Details
BioGPS Gene Atlas204172_atCD105+_Endothelial364.40035.280Details
BioGPS Gene Atlas204172_atCD14+_Monocytes11.55035.280Details
BioGPS Gene Atlas204172_atCD19+_BCells(neg._sel.)10.35035.280Details
BioGPS Gene Atlas204172_atCD33+_Myeloid19.65035.280Details
BioGPS Gene Atlas204172_atCD34+64.25035.280Details
BioGPS Gene Atlas204172_atCD4+_Tcells18.20035.280Details
BioGPS Gene Atlas204172_atCD56+_NKCells11.75035.280Details
BioGPS Gene Atlas204172_atCD71+_EarlyErythroid556.20035.280Details
BioGPS Gene Atlas204172_atCD8+_Tcells14.80035.280Details
BioGPS Gene Atlas204172_atCardiacMyocytes19.45035.280Details
BioGPS Gene Atlas204172_atCaudatenucleus18.55035.280Details
BioGPS Gene Atlas204172_atCerebellum8.85035.280Details
BioGPS Gene Atlas204172_atCerebellumPeduncles13.40035.280Details
BioGPS Gene Atlas204172_atCiliaryGanglion8.45035.280Details
BioGPS Gene Atlas204172_atCingulateCortex12.45035.280Details
BioGPS Gene Atlas204172_atColorectaladenocarcinoma12.60035.280Details
BioGPS Gene Atlas204172_atDorsalRootGanglion9.20035.280Details
BioGPS Gene Atlas204172_atFetalThyroid9.85035.280Details
BioGPS Gene Atlas204172_atFetalbrain8.55035.280Details
BioGPS Gene Atlas204172_atFetalliver475.95035.280Details
BioGPS Gene Atlas204172_atFetallung30.70035.280Details
BioGPS Gene Atlas204172_atGlobusPallidus7.00035.280Details
BioGPS Gene Atlas204172_atHeart16.45035.280Details
BioGPS Gene Atlas204172_atHypothalamus37.70035.280Details
BioGPS Gene Atlas204172_atKidney8.35035.280Details
BioGPS Gene Atlas204172_atLeukemia_chronicMyelogenousK-562125.05035.280Details
BioGPS Gene Atlas204172_atLeukemia_promyelocytic-HL-607.05035.280Details
BioGPS Gene Atlas204172_atLeukemialymphoblastic(MOLT-4)13.55035.280Details
BioGPS Gene Atlas204172_atLiver15.65035.280Details
BioGPS Gene Atlas204172_atLung11.65035.280Details
BioGPS Gene Atlas204172_atLymphnode9.15035.280Details
BioGPS Gene Atlas204172_atLymphoma_burkitts(Daudi)11.15035.280Details
BioGPS Gene Atlas204172_atLymphoma_burkitts(Raji)10.70035.280Details
BioGPS Gene Atlas204172_atMedullaOblongata19.50035.280Details
BioGPS Gene Atlas204172_atOccipitalLobe17.55035.280Details
BioGPS Gene Atlas204172_atOlfactoryBulb7.05035.280Details
BioGPS Gene Atlas204172_atOvary6.60035.280Details
BioGPS Gene Atlas204172_atPancreas8.25035.280Details
BioGPS Gene Atlas204172_atPancreaticIslet10.10035.280Details
BioGPS Gene Atlas204172_atParietalLobe13.50035.280Details
BioGPS Gene Atlas204172_atPituitary10.65035.280Details
BioGPS Gene Atlas204172_atPlacenta14.45035.280Details
BioGPS Gene Atlas204172_atPons10.35035.280Details
BioGPS Gene Atlas204172_atPrefrontalCortex37.35035.280Details
BioGPS Gene Atlas204172_atProstate19.05035.280Details
BioGPS Gene Atlas204172_atSalivarygland9.60035.280Details
BioGPS Gene Atlas204172_atSkeletalMuscle13.90035.280Details
BioGPS Gene Atlas204172_atSkin9.90035.280Details
BioGPS Gene Atlas204172_atSmoothMuscle13.85035.280Details
BioGPS Gene Atlas204172_atSpinalcord36.25035.280Details
BioGPS Gene Atlas204172_atSubthalamicNucleus10.25035.280Details
BioGPS Gene Atlas204172_atSuperiorCervicalGanglion14.95035.280Details
BioGPS Gene Atlas204172_atTemporalLobe10.55035.280Details
BioGPS Gene Atlas204172_atTestis6.95035.280Details
BioGPS Gene Atlas204172_atTestisGermCell6.80035.280Details
BioGPS Gene Atlas204172_atTestisIntersitial8.60035.280Details
BioGPS Gene Atlas204172_atTestisLeydigCell10.30035.280Details
BioGPS Gene Atlas204172_atTestisSeminiferousTubule8.10035.280Details
BioGPS Gene Atlas204172_atThalamus11.90035.280Details
BioGPS Gene Atlas204172_atThymus17.85035.280Details
BioGPS Gene Atlas204172_atThyroid13.45035.280Details
BioGPS Gene Atlas204172_atTongue11.55035.280Details
BioGPS Gene Atlas204172_atTonsil10.40035.280Details
BioGPS Gene Atlas204172_atTrachea8.40035.280Details
BioGPS Gene Atlas204172_atTrigeminalGanglion12.75035.280Details
BioGPS Gene Atlas204172_atUterus11.60035.280Details
BioGPS Gene Atlas204172_atUterusCorpus10.90035.280Details
BioGPS Gene Atlas204172_atWholeBlood13.20035.280Details
BioGPS Gene Atlas204172_atWholebrain36.95035.280Details
BioGPS Gene Atlas204172_atcolon10.80035.280Details
BioGPS Gene Atlas204172_atpineal_day11.72035.280Details
BioGPS Gene Atlas204172_atpineal_night11.72035.280Details
BioGPS Gene Atlas204172_atretina20.25035.280Details
BioGPS Gene Atlas204172_atsmall_intestine11.55035.280Details
BioGPS NCI60204172_at786638.581412.800Details
BioGPS NCI60204172_atA172190.539412.800Details
BioGPS NCI60204172_atA20488.793412.800Details
BioGPS NCI60204172_atA361258.977412.800Details
BioGPS NCI60204172_atA498257.271412.800Details
BioGPS NCI60204172_atA549313.522412.800Details
BioGPS NCI60204172_atACC3127.670412.800Details
BioGPS NCI60204172_atACHN192.709412.800Details
BioGPS NCI60204172_atALVA31350.421412.800Details
BioGPS NCI60204172_atCAKI1237.662412.800Details
BioGPS NCI60204172_atCCRT CEM245.454412.800Details
BioGPS NCI60204172_atCOLO205276.779412.800Details
BioGPS NCI60204172_atDLD11122.930412.800Details
BioGPS NCI60204172_atDU145192.256412.800Details
BioGPS NCI60204172_atEKVX192.885412.800Details
BioGPS NCI60204172_atGM133746.717412.800Details
BioGPS NCI60204172_atGM1600359.874412.800Details
BioGPS NCI60204172_atGM2313244.422412.800Details
BioGPS NCI60204172_atGM23451486.273412.800Details
BioGPS NCI60204172_atGM2493390.869412.800Details
BioGPS NCI60204172_atGM97335.814412.800Details
BioGPS NCI60204172_atHCC2998175.089412.800Details
BioGPS NCI60204172_atHCT1163466.339412.800Details
BioGPS NCI60204172_atHCT15462.004412.800Details
BioGPS NCI60204172_atHEK 293 T-rex311.066412.800Details
BioGPS NCI60204172_atHEK 293T403.245412.800Details
BioGPS NCI60204172_atHEK293539.292412.800Details
BioGPS NCI60204172_atHELA36.451412.800Details
BioGPS NCI60204172_atHEPG2218.290412.800Details
BioGPS NCI60204172_atHL6011.341412.800Details
BioGPS NCI60204172_atHOP62951.363412.800Details
BioGPS NCI60204172_atHOP92269.422412.800Details
BioGPS NCI60204172_atHS578T530.050412.800Details
BioGPS NCI60204172_atHSG72.127412.800Details
BioGPS NCI60204172_atHT1080230.612412.800Details
BioGPS NCI60204172_atHT29316.078412.800Details
BioGPS NCI60204172_atIGROV1207.201412.800Details
BioGPS NCI60204172_atIOSE80238.998412.800Details
BioGPS NCI60204172_atJURKAT254.438412.800Details
BioGPS NCI60204172_atK562322.400412.800Details
BioGPS NCI60204172_atKM12400.033412.800Details
BioGPS NCI60204172_atLN18199.354412.800Details
BioGPS NCI60204172_atLNCAP130.321412.800Details
BioGPS NCI60204172_atLOX IMVI285.816412.800Details
BioGPS NCI60204172_atM14576.654412.800Details
BioGPS NCI60204172_atMALME 3M521.496412.800Details
BioGPS NCI60204172_atMCF7123.844412.800Details
BioGPS NCI60204172_atMD MB2311680.405412.800Details
BioGPS NCI60204172_atMDA MB4351044.885412.800Details
BioGPS NCI60204172_atMOLT4205.067412.800Details
BioGPS NCI60204172_atNCI 460144.838412.800Details
BioGPS NCI60204172_atNCI H226111.841412.800Details
BioGPS NCI60204172_atNCI H23184.434412.800Details
BioGPS NCI60204172_atNCI H322M132.772412.800Details
BioGPS NCI60204172_atNCVADR RES182.344412.800Details
BioGPS NCI60204172_atOVCAR3362.103412.800Details
BioGPS NCI60204172_atOVCAR4383.551412.800Details
BioGPS NCI60204172_atOVCAR5295.225412.800Details
BioGPS NCI60204172_atOVCAR8204.284412.800Details
BioGPS NCI60204172_atPANC1111.407412.800Details
BioGPS NCI60204172_atRL789.996412.800Details
BioGPS NCI60204172_atRPMI 8226166.698412.800Details
BioGPS NCI60204172_atRS11846244.615412.800Details
BioGPS NCI60204172_atRXF393323.490412.800Details
BioGPS NCI60204172_atSAOS236.435412.800Details
BioGPS NCI60204172_atSF268239.085412.800Details
BioGPS NCI60204172_atSF2951803.660412.800Details
BioGPS NCI60204172_atSF539320.149412.800Details
BioGPS NCI60204172_atSHSYSY+RA164.796412.800Details
BioGPS NCI60204172_atSHSYSY-RA135.103412.800Details
BioGPS NCI60204172_atSKMEL21017.860412.800Details
BioGPS NCI60204172_atSKMEL28246.420412.800Details
BioGPS NCI60204172_atSKMEL5816.180412.800Details
BioGPS NCI60204172_atSKOV3495.333412.800Details
BioGPS NCI60204172_atSN12C213.431412.800Details
BioGPS NCI60204172_atSNB19255.381412.800Details
BioGPS NCI60204172_atSNB75244.088412.800Details
BioGPS NCI60204172_atSR40.416412.800Details
BioGPS NCI60204172_atSW620404.401412.800Details
BioGPS NCI60204172_atT24249.060412.800Details
BioGPS NCI60204172_atT3M4286.709412.800Details
BioGPS NCI60204172_atTK10382.655412.800Details
BioGPS NCI60204172_atU118489.205412.800Details
BioGPS NCI60204172_atU138484.736412.800Details
BioGPS NCI60204172_atU20S388.531412.800Details
BioGPS NCI60204172_atU251167.941412.800Details
BioGPS NCI60204172_atU87274.632412.800Details
BioGPS NCI60204172_atUACC257515.361412.800Details
BioGPS NCI60204172_atUACC62318.526412.800Details
BioGPS NCI60204172_atUO31573.146412.800Details
BioGPS NCI60204172_atZR75_1154.992412.800Details
BioGPS NCI60204172_atastrocytes106.515412.800Details
BioGPS NCI60204172_athuh-7612.628412.800Details