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Gene ID: 1369 | CPN1 Antibody Resource


CPN1 Antibody Resource
Gene Full Name: 
carboxypeptidase N, polypeptide 1
Uniprot: 
P15169
Protein Name: 
carboxypeptidase N catalytic chain
Nucleotide: 
NM_001308
Alias: 
CPN;SCPN;
Ensembl: 
ENSG00000120054
Location: 
10q24.2
HPRD: 
09120
NCBI Gene: 
1369
MIM: 
603103

Summary: 
Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008]
Function: 
Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
Subcellular location: 
Secreted › extracellular space.
PTM: 
Disulfide bond;
Disease: 
Carboxypeptidase N deficiency (CPND) [MIM:212070]: Patients affected present some combination of angioedema or chronic urticaria, as well as hay fever or asthma, and have also slightly depressed serum carboxy peptidase N, suggestive of autosomal recessive inheritance of this disorder. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP51940_P050 CPN1 antibody - middle region (ARP51940_P050) Polyclonal Dog, Guinea pig, Horse, Human, Pig, Rabbit WB 50ug $289 Details
Polyclonal Antibody ARP51939_P050 CPN1 antibody - middle region (ARP51939_P050) Polyclonal Dog, Guinea pig, Horse, Human, Pig, Rabbit, Zebrafish IHC, WB 50ug $289 Details
Polyclonal Antibody OAAB04333 CPN1 antibody - N-terminal region (OAAB04333) Human; Mouse WB, ELISA 400ul $289 Details
Polyclonal Antibody OAAB09172 CPN1 antibody - center region (OAAB09172) Human WB, IHC, FC 400ul $289 Details
Polyclonal Antibody OAAF03444 CPN1 Antibody (OAAF03444) Polyclonal Human WB, ELISA 100 ug $289 Details

Show all CPN1 antibodies


Product Images
CPN1 antibody - middle region (ARP51939_P050) in Human Heart cells using Immunohistochemistry

Sample Type: Human Heart

CPN1 antibody - middle region (ARP51939_P050) in Transfected 293T cells using Western Blot

Sample Type: Transfected 293T

CPN1 antibody - middle region (ARP51940_P050) in Transfected 293T cells using Western Blot

Sample Type: Transfected 293T

CPN1 antibody - N-terminal region (OAAB04333) in CPN1 cells using Western Blot

Sample Type: CPN1

CPN1 antibody - N-terminal region (OAAB04333) in K562, CEM, HepG2 and mouse liver cells using Western Blot

Sample Type: K562, CEM, HepG2 and mouse liver

CPN1 antibody - center region (OAAB09172) in 293 cells using Flow Cytometry

Sample Type: 293

CPN1 antibody - center region (OAAB09172) in 293 cells using Western Blot

Sample Type: 293

CPN1 antibody - center region (OAAB09172) in Human Liver cells using Immunohistochemistry

Sample Type: Human Liver

CPN1 Antibody (OAAF03444) in RAW264.7 cells using Western Blot

Sample Type: RAW264.7


CPN1 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP51939 Bovine CPN1 antibody; Bos taurus CPN1 antibody G5E5V0 100.0%
ARP51940 Bovine CPN1 antibody; Bos taurus CPN1 antibody G5E5V0 100.0%
ARP51939 Bovine CPN1 antibody; Bos taurus CPN1 antibody Q2KJ83 100.0%
ARP51940 Bovine CPN1 antibody; Bos taurus CPN1 antibody Q2KJ83 100.0%
ARP51939 Cat CPN1 antibody; Felis catus CPN1 antibody M3VV12 100.0%
ARP51940 Cat CPN1 antibody; Felis catus CPN1 antibody M3VV12 100.0%
ARP51939 Chicken CPN1 antibody; Gallus gallus CPN1 antibody E1C7M0 92.0%
ARP51939 Collared flycatcher CPN1 antibody; Ficedula albicollis CPN1 antibody U3K037 92.0%
ARP51939 Dog CPN1 antibody; Canis familiaris CPN1 antibody E2QZ95 100.0%
ARP51940 Dog CPN1 antibody; Canis familiaris CPN1 antibody E2QZ95 100.0%
ARP51939 Dog CPN1 antibody; Canis familiaris CPN1 antibody E2RNG3 100.0%
ARP51940 Dog CPN1 antibody; Canis familiaris CPN1 antibody E2RNG3 100.0%
ARP51939 Dog CPN1 antibody; Canis familiaris CPN1 antibody F6XTZ1 100.0%
ARP51940 Dog CPN1 antibody; Canis familiaris CPN1 antibody F6XTZ1 100.0%
ARP51939 Domestic duck CPN1 antibody; Anas platyrhynchos CPN1 antibody U3IUJ6 92.0%
ARP51939 European domestic ferret CPN1 antibody; Mustela putorius furo CPN1 antibody M3YZW6 100.0%
ARP51940 European domestic ferret CPN1 antibody; Mustela putorius furo CPN1 antibody M3YZW6 100.0%
ARP51940 Giant panda CPN1 antibody; Ailuropoda melanoleuca CPN1 antibody G1LKA1 100.0%
ARP51939 Giant panda CPN1 antibody; Ailuropoda melanoleuca CPN1 antibody G1LKA1 100.0%
ARP51939 Gray short-tailed opossum CPN1 antibody; Monodelphis domestica CPN1 antibody F6T1P4 92.0%
ARP51940 Gray short-tailed opossum CPN1 antibody; Monodelphis domestica CPN1 antibody F6T1P4 79.0%
ARP51939 Green anole CPN1 antibody; Anolis carolinensis CPN1 antibody G1KCP4 85.0%
ARP51939 Horse CPN1 antibody; Equus caballus CPN1 antibody F6WZA8 100.0%
ARP51940 Horse CPN1 antibody; Equus caballus CPN1 antibody F6WZA8 100.0%
ARP51939 Human CPN1 antibody; Homo sapiens CPN1 antibody P15169 100.0%
ARP51940 Human CPN1 antibody; Homo sapiens CPN1 antibody P15169 100.0%
ARP51939 Human CPN1 antibody; Homo sapiens CPN1 antibody B1AP58 100.0%
ARP51940 Human CPN1 antibody; Homo sapiens CPN1 antibody B1AP58 100.0%
ARP51939 Human CPN1 antibody; Homo sapiens CPN1 antibody B1AP59 100.0%
ARP51940 Human CPN1 antibody; Homo sapiens CPN1 antibody B1AP59 100.0%
ARP51939 Mouse CPN1 antibody; Mus musculus CPN1 antibody Q9JJN5 100.0%
ARP51940 Mouse CPN1 antibody; Mus musculus CPN1 antibody Q9JJN5 100.0%
ARP51939 Pig CPN1 antibody; Sus scrofa CPN1 antibody F1S8V7 100.0%
ARP51940 Pig CPN1 antibody; Sus scrofa CPN1 antibody F1S8V7 100.0%
ARP51939 Rabbit CPN1 antibody; Oryctolagus cuniculus CPN1 antibody G1SH58 100.0%
ARP51940 Rabbit CPN1 antibody; Oryctolagus cuniculus CPN1 antibody G1SH58 100.0%
ARP51939 Rat CPN1 antibody; Rattus norvegicus CPN1 antibody Q9EQV8 100.0%
ARP51940 Rat CPN1 antibody; Rattus norvegicus CPN1 antibody Q9EQV8 100.0%
ARP51939 Small-eared galago CPN1 antibody; Otolemur garnettii CPN1 antibody H0WYL4 100.0%
ARP51940 Small-eared galago CPN1 antibody; Otolemur garnettii CPN1 antibody H0WYL4 93.0%
ARP51939 Sumatran orangutan CPN1 antibody; Pongo abelii CPN1 antibody K7ETH1 100.0%
ARP51940 Sumatran orangutan CPN1 antibody; Pongo abelii CPN1 antibody K7ETH1 100.0%
ARP51939 Tasmanian devil CPN1 antibody; Sarcophilus harrisii CPN1 antibody G3WAE7 92.0%
ARP51940 Tasmanian devil CPN1 antibody; Sarcophilus harrisii CPN1 antibody G3WAE7 79.0%
ARP51939 Thirteen-lined ground squirrel CPN1 antibody; Spermophilus tridecemlineatus CPN1 antibody I3MCF7 100.0%
ARP51940 Thirteen-lined ground squirrel CPN1 antibody; Spermophilus tridecemlineatus CPN1 antibody I3MCF7 100.0%
ARP51940 White-tufted-ear marmoset CPN1 antibody; Callithrix jacchus CPN1 antibody F7ICG5 100.0%
ARP51940 White-tufted-ear marmoset CPN1 antibody; Callithrix jacchus CPN1 antibody F7IEV6 93.0%
ARP51940 White-tufted-ear marmoset CPN1 antibody; Callithrix jacchus CPN1 antibody F7IH82 93.0%
ARP51939 White-tufted-ear marmoset CPN1 antibody; Callithrix jacchus CPN1 antibody F7ICG5 92.0%
ARP51939 White-tufted-ear marmoset CPN1 antibody; Callithrix jacchus CPN1 antibody F7IEV6 92.0%
ARP51939 White-tufted-ear marmoset CPN1 antibody; Callithrix jacchus CPN1 antibody F7IH82 92.0%
ARP51939 Zebra finch CPN1 antibody; Taeniopygia guttata CPN1 antibody H0ZFU2 92.0%
ARP51939 Zebrafish CPN1 antibody; Danio rerio CPN1 antibody Q6NY94 85.0%
ARP51939 Zebrafish CPN1 antibody; Danio rerio CPN1 antibody U3JB00 85.0%
ARP51939 Zebrafish CPN1 antibody; Danio rerio CPN1 antibody A8WGN2 85.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas206256_at721_B_lymphoblasts5.9008.410Details
BioGPS Gene Atlas206256_atAdipocyte4.9508.410Details
BioGPS Gene Atlas206256_atAdrenalCortex5.7508.410Details
BioGPS Gene Atlas206256_atAdrenalgland4.4508.410Details
BioGPS Gene Atlas206256_atAmygdala5.1508.410Details
BioGPS Gene Atlas206256_atAppendix5.7508.410Details
BioGPS Gene Atlas206256_atAtrioventricularNode5.2008.410Details
BioGPS Gene Atlas206256_atBDCA4+_DentriticCells5.2008.410Details
BioGPS Gene Atlas206256_atBonemarrow5.1508.410Details
BioGPS Gene Atlas206256_atBronchialEpithelialCells4.8008.410Details
BioGPS Gene Atlas206256_atCD105+_Endothelial4.9008.410Details
BioGPS Gene Atlas206256_atCD14+_Monocytes5.1008.410Details
BioGPS Gene Atlas206256_atCD19+_BCells(neg._sel.)5.2008.410Details
BioGPS Gene Atlas206256_atCD33+_Myeloid6.1508.410Details
BioGPS Gene Atlas206256_atCD34+6.1008.410Details
BioGPS Gene Atlas206256_atCD4+_Tcells5.2508.410Details
BioGPS Gene Atlas206256_atCD56+_NKCells5.6008.410Details
BioGPS Gene Atlas206256_atCD71+_EarlyErythroid4.7508.410Details
BioGPS Gene Atlas206256_atCD8+_Tcells4.7008.410Details
BioGPS Gene Atlas206256_atCardiacMyocytes7.4008.410Details
BioGPS Gene Atlas206256_atCaudatenucleus4.9508.410Details
BioGPS Gene Atlas206256_atCerebellum4.1508.410Details
BioGPS Gene Atlas206256_atCerebellumPeduncles7.4008.410Details
BioGPS Gene Atlas206256_atCiliaryGanglion3.8008.410Details
BioGPS Gene Atlas206256_atCingulateCortex11.9508.410Details
BioGPS Gene Atlas206256_atColorectaladenocarcinoma4.9508.410Details
BioGPS Gene Atlas206256_atDorsalRootGanglion5.4008.410Details
BioGPS Gene Atlas206256_atFetalThyroid5.1508.410Details
BioGPS Gene Atlas206256_atFetalbrain5.4008.410Details
BioGPS Gene Atlas206256_atFetalliver47.0508.410Details
BioGPS Gene Atlas206256_atFetallung4.9508.410Details
BioGPS Gene Atlas206256_atGlobusPallidus3.9008.410Details
BioGPS Gene Atlas206256_atHeart7.2008.410Details
BioGPS Gene Atlas206256_atHypothalamus5.5008.410Details
BioGPS Gene Atlas206256_atKidney4.3008.410Details
BioGPS Gene Atlas206256_atLeukemia_chronicMyelogenousK-5624.7008.410Details
BioGPS Gene Atlas206256_atLeukemia_promyelocytic-HL-604.5008.410Details
BioGPS Gene Atlas206256_atLeukemialymphoblastic(MOLT-4)4.6008.410Details
BioGPS Gene Atlas206256_atLiver180.3508.410Details
BioGPS Gene Atlas206256_atLung5.6508.410Details
BioGPS Gene Atlas206256_atLymphnode4.3008.410Details
BioGPS Gene Atlas206256_atLymphoma_burkitts(Daudi)11.8508.410Details
BioGPS Gene Atlas206256_atLymphoma_burkitts(Raji)7.1008.410Details
BioGPS Gene Atlas206256_atMedullaOblongata4.7008.410Details
BioGPS Gene Atlas206256_atOccipitalLobe4.6008.410Details
BioGPS Gene Atlas206256_atOlfactoryBulb4.0508.410Details
BioGPS Gene Atlas206256_atOvary3.4508.410Details
BioGPS Gene Atlas206256_atPancreas4.0008.410Details
BioGPS Gene Atlas206256_atPancreaticIslet6.1008.410Details
BioGPS Gene Atlas206256_atParietalLobe5.5508.410Details
BioGPS Gene Atlas206256_atPituitary7.4008.410Details
BioGPS Gene Atlas206256_atPlacenta5.0508.410Details
BioGPS Gene Atlas206256_atPons8.5008.410Details
BioGPS Gene Atlas206256_atPrefrontalCortex6.1008.410Details
BioGPS Gene Atlas206256_atProstate5.8508.410Details
BioGPS Gene Atlas206256_atSalivarygland4.1508.410Details
BioGPS Gene Atlas206256_atSkeletalMuscle26.7008.410Details
BioGPS Gene Atlas206256_atSkin8.7508.410Details
BioGPS Gene Atlas206256_atSmoothMuscle5.7508.410Details
BioGPS Gene Atlas206256_atSpinalcord5.4508.410Details
BioGPS Gene Atlas206256_atSubthalamicNucleus4.8008.410Details
BioGPS Gene Atlas206256_atSuperiorCervicalGanglion6.5008.410Details
BioGPS Gene Atlas206256_atTemporalLobe7.2508.410Details
BioGPS Gene Atlas206256_atTestis4.4508.410Details
BioGPS Gene Atlas206256_atTestisGermCell4.1008.410Details
BioGPS Gene Atlas206256_atTestisIntersitial4.6508.410Details
BioGPS Gene Atlas206256_atTestisLeydigCell6.8008.410Details
BioGPS Gene Atlas206256_atTestisSeminiferousTubule6.3508.410Details
BioGPS Gene Atlas206256_atThalamus5.2508.410Details
BioGPS Gene Atlas206256_atThymus4.7008.410Details
BioGPS Gene Atlas206256_atThyroid6.2508.410Details
BioGPS Gene Atlas206256_atTongue10.2008.410Details
BioGPS Gene Atlas206256_atTonsil5.0008.410Details
BioGPS Gene Atlas206256_atTrachea6.2508.410Details
BioGPS Gene Atlas206256_atTrigeminalGanglion9.1008.410Details
BioGPS Gene Atlas206256_atUterus4.1008.410Details
BioGPS Gene Atlas206256_atUterusCorpus9.5508.410Details
BioGPS Gene Atlas206256_atWholeBlood5.4508.410Details
BioGPS Gene Atlas206256_atWholebrain5.2008.410Details
BioGPS Gene Atlas206256_atcolon5.0008.410Details
BioGPS Gene Atlas206256_atpineal_day6.0208.410Details
BioGPS Gene Atlas206256_atpineal_night5.8808.410Details
BioGPS Gene Atlas206256_atretina6.0258.410Details
BioGPS Gene Atlas206256_atsmall_intestine4.7008.410Details
BioGPS NCI60206256_at7864.89067.100Details
BioGPS NCI60206256_atA1724.64067.100Details
BioGPS NCI60206256_atA2044.75967.100Details
BioGPS NCI60206256_atA36137.82267.100Details
BioGPS NCI60206256_atA4984.78767.100Details
BioGPS NCI60206256_atA5494.85067.100Details
BioGPS NCI60206256_atACC34.99967.100Details
BioGPS NCI60206256_atACHN4.60667.100Details
BioGPS NCI60206256_atALVA315.18367.100Details
BioGPS NCI60206256_atCAKI14.90367.100Details
BioGPS NCI60206256_atCCRT CEM5.77167.100Details
BioGPS NCI60206256_atCOLO2054.87767.100Details
BioGPS NCI60206256_atDLD14.74467.100Details
BioGPS NCI60206256_atDU1454.50667.100Details
BioGPS NCI60206256_atEKVX4.55267.100Details
BioGPS NCI60206256_atGM1334.90467.100Details
BioGPS NCI60206256_atGM16004.96067.100Details
BioGPS NCI60206256_atGM23134.85367.100Details
BioGPS NCI60206256_atGM23454.84867.100Details
BioGPS NCI60206256_atGM24934.95767.100Details
BioGPS NCI60206256_atGM975.28467.100Details
BioGPS NCI60206256_atHCC29984.25567.100Details
BioGPS NCI60206256_atHCT1164.82267.100Details
BioGPS NCI60206256_atHCT154.60667.100Details
BioGPS NCI60206256_atHEK 293 T-rex4.94267.100Details
BioGPS NCI60206256_atHEK 293T4.79267.100Details
BioGPS NCI60206256_atHEK2934.80367.100Details
BioGPS NCI60206256_atHELA4.45367.100Details
BioGPS NCI60206256_atHEPG2279.51067.100Details
BioGPS NCI60206256_atHL605.10967.100Details
BioGPS NCI60206256_atHOP624.80767.100Details
BioGPS NCI60206256_atHOP924.57167.100Details
BioGPS NCI60206256_atHS578T4.75267.100Details
BioGPS NCI60206256_atHSG4.68367.100Details
BioGPS NCI60206256_atHT10804.77967.100Details
BioGPS NCI60206256_atHT295.17767.100Details
BioGPS NCI60206256_atIGROV14.75667.100Details
BioGPS NCI60206256_atIOSE804.75967.100Details
BioGPS NCI60206256_atJURKAT4.78667.100Details
BioGPS NCI60206256_atK5625.18667.100Details
BioGPS NCI60206256_atKM124.93267.100Details
BioGPS NCI60206256_atLN184.53567.100Details
BioGPS NCI60206256_atLNCAP4.79067.100Details
BioGPS NCI60206256_atLOX IMVI4.77867.100Details
BioGPS NCI60206256_atM141541.86767.100Details
BioGPS NCI60206256_atMALME 3M90.93367.100Details
BioGPS NCI60206256_atMCF74.62967.100Details
BioGPS NCI60206256_atMD MB2314.91667.100Details
BioGPS NCI60206256_atMDA MB435932.55267.100Details
BioGPS NCI60206256_atMOLT44.99667.100Details
BioGPS NCI60206256_atNCI 4604.89467.100Details
BioGPS NCI60206256_atNCI H2264.86967.100Details
BioGPS NCI60206256_atNCI H234.76367.100Details
BioGPS NCI60206256_atNCI H322M4.78167.100Details
BioGPS NCI60206256_atNCVADR RES4.64967.100Details
BioGPS NCI60206256_atOVCAR34.93167.100Details
BioGPS NCI60206256_atOVCAR44.77767.100Details
BioGPS NCI60206256_atOVCAR54.70167.100Details
BioGPS NCI60206256_atOVCAR84.37667.100Details
BioGPS NCI60206256_atPANC14.88767.100Details
BioGPS NCI60206256_atRL74.85467.100Details
BioGPS NCI60206256_atRPMI 82264.87467.100Details
BioGPS NCI60206256_atRS118464.93567.100Details
BioGPS NCI60206256_atRXF3934.77667.100Details
BioGPS NCI60206256_atSAOS24.85967.100Details
BioGPS NCI60206256_atSF2684.78867.100Details
BioGPS NCI60206256_atSF2954.69767.100Details
BioGPS NCI60206256_atSF5394.46267.100Details
BioGPS NCI60206256_atSHSYSY+RA4.59167.100Details
BioGPS NCI60206256_atSHSYSY-RA4.75967.100Details
BioGPS NCI60206256_atSKMEL2113.55967.100Details
BioGPS NCI60206256_atSKMEL281992.63667.100Details
BioGPS NCI60206256_atSKMEL51011.99367.100Details
BioGPS NCI60206256_atSKOV34.88467.100Details
BioGPS NCI60206256_atSN12C4.76767.100Details
BioGPS NCI60206256_atSNB194.47367.100Details
BioGPS NCI60206256_atSNB754.71067.100Details
BioGPS NCI60206256_atSR4.90367.100Details
BioGPS NCI60206256_atSW6204.78967.100Details
BioGPS NCI60206256_atT244.98167.100Details
BioGPS NCI60206256_atT3M44.92867.100Details
BioGPS NCI60206256_atTK104.76667.100Details
BioGPS NCI60206256_atU1184.80167.100Details
BioGPS NCI60206256_atU1384.82667.100Details
BioGPS NCI60206256_atU20S5.07267.100Details
BioGPS NCI60206256_atU2514.69967.100Details
BioGPS NCI60206256_atU874.78367.100Details
BioGPS NCI60206256_atUACC257231.68667.100Details
BioGPS NCI60206256_atUACC62529.43067.100Details
BioGPS NCI60206256_atUO314.56667.100Details
BioGPS NCI60206256_atZR75_14.88067.100Details
BioGPS NCI60206256_atastrocytes5.14167.100Details
BioGPS NCI60206256_athuh-710.89567.100Details