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Gene ID: 64506 | CPEB1 Antibody Resource


CPEB1 Antibody Resource
Gene Full Name: 
cytoplasmic polyadenylation element binding protein 1
Uniprot: 
Q9BZB8
Protein Name: 
cytoplasmic polyadenylation element-binding protein 1
Nucleotide: 
XM_005272443
Alias: 
CEBP;CPEB;CPE-BP1;
Ensembl: 
ENSG00000214575
Location: 
15q25.2
HPRD: 
09553
NCBI Gene: 
64506
MIM: 
607342

Summary: 
This gene encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function: 
Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation . Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses . Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation . Induces the assembly of stress granules in the absence of stress.
Subcellular location: 
Cytoplasm › P-body. Cytoplasmic granule. Cell junction › synapse. Membrane. Cell junction › synapse › postsynaptic cell membrane › postsynaptic density. Cell projection › dendrite. Note: Also found in stress granules. Recruited to stress granules (SGs) upon arsenite treatment. In dendrites . Localizes in synaptosomes at dendritic synapses of neurons . Strongly enriched in postsynaptic density (PSD) fractions . Transported into dendrites in a microtubule-dependent fashion and colocalizes in mRNA-containing particles with TACC3, dynein and kinesin . Membrane-associated . Colocalizes at excitatory synapses with members of the polyadenylation and translation complex factors (CPSF, APLP1, TACC3, AURKA, SYP, etc.) including CPE-containing RNAs .
PTM: 
Phosphoprotein;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAEB01216 CPEB1 Antibody (OAEB01216) Bovine, Dog, Horse, Human, Pig, Rabbit, Zebrafish WB 0.1mg $289 Details
Polyclonal Antibody OAPB00712 CPEB1 Antibody (OAPB00712) Polyclonal Human; Mouse; Rat ELISA, WB 0.1 mg $300 Details
Polyclonal Antibody OAAB12048 CPEB1 antibody - C - terminal region (OAAB12048) Human WB 400ul $289 Details

Show all CPEB1 antibodies


Product Images
CPEB1 antibody - C - terminal region (OAAB12048) in A2058 cells using Western Blot

Sample Type: A2058

CPEB1 Antibody (OAEB01216) in Human Brain cells using Western Blot

Sample Type: Human Brain

CPEB1 Antibody (OAPB00712) in rat brain cells using Western Blot

Sample Type: rat brain


CPEB1 Protocols

Publications

Related Gene Trend Categories

Species
Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas219578_s_at721_B_lymphoblasts4.20011.800Details
BioGPS Gene Atlas219578_s_atAdipocyte8.30011.800Details
BioGPS Gene Atlas219578_s_atAdrenalCortex5.15011.800Details
BioGPS Gene Atlas219578_s_atAdrenalgland4.25011.800Details
BioGPS Gene Atlas219578_s_atAmygdala27.40011.800Details
BioGPS Gene Atlas219578_s_atAppendix6.60011.800Details
BioGPS Gene Atlas219578_s_atAtrioventricularNode4.10011.800Details
BioGPS Gene Atlas219578_s_atBDCA4+_DentriticCells4.25011.800Details
BioGPS Gene Atlas219578_s_atBonemarrow4.80011.800Details
BioGPS Gene Atlas219578_s_atBronchialEpithelialCells4.80011.800Details
BioGPS Gene Atlas219578_s_atCD105+_Endothelial4.45011.800Details
BioGPS Gene Atlas219578_s_atCD14+_Monocytes4.90011.800Details
BioGPS Gene Atlas219578_s_atCD19+_BCells(neg._sel.)4.00011.800Details
BioGPS Gene Atlas219578_s_atCD33+_Myeloid5.05011.800Details
BioGPS Gene Atlas219578_s_atCD34+6.00011.800Details
BioGPS Gene Atlas219578_s_atCD4+_Tcells4.70011.800Details
BioGPS Gene Atlas219578_s_atCD56+_NKCells5.10011.800Details
BioGPS Gene Atlas219578_s_atCD71+_EarlyErythroid4.30011.800Details
BioGPS Gene Atlas219578_s_atCD8+_Tcells4.05011.800Details
BioGPS Gene Atlas219578_s_atCardiacMyocytes6.25011.800Details
BioGPS Gene Atlas219578_s_atCaudatenucleus6.00011.800Details
BioGPS Gene Atlas219578_s_atCerebellum20.30011.800Details
BioGPS Gene Atlas219578_s_atCerebellumPeduncles12.20011.800Details
BioGPS Gene Atlas219578_s_atCiliaryGanglion3.70011.800Details
BioGPS Gene Atlas219578_s_atCingulateCortex12.55011.800Details
BioGPS Gene Atlas219578_s_atColorectaladenocarcinoma4.85011.800Details
BioGPS Gene Atlas219578_s_atDorsalRootGanglion10.05011.800Details
BioGPS Gene Atlas219578_s_atFetalThyroid4.70011.800Details
BioGPS Gene Atlas219578_s_atFetalbrain4.80011.800Details
BioGPS Gene Atlas219578_s_atFetalliver4.20011.800Details
BioGPS Gene Atlas219578_s_atFetallung3.95011.800Details
BioGPS Gene Atlas219578_s_atGlobusPallidus4.60011.800Details
BioGPS Gene Atlas219578_s_atHeart6.35011.800Details
BioGPS Gene Atlas219578_s_atHypothalamus36.40011.800Details
BioGPS Gene Atlas219578_s_atKidney3.95011.800Details
BioGPS Gene Atlas219578_s_atLeukemia_chronicMyelogenousK-5628.25011.800Details
BioGPS Gene Atlas219578_s_atLeukemia_promyelocytic-HL-604.20011.800Details
BioGPS Gene Atlas219578_s_atLeukemialymphoblastic(MOLT-4)3.90011.800Details
BioGPS Gene Atlas219578_s_atLiver6.55011.800Details
BioGPS Gene Atlas219578_s_atLung5.50011.800Details
BioGPS Gene Atlas219578_s_atLymphnode4.20011.800Details
BioGPS Gene Atlas219578_s_atLymphoma_burkitts(Daudi)6.15011.800Details
BioGPS Gene Atlas219578_s_atLymphoma_burkitts(Raji)6.75011.800Details
BioGPS Gene Atlas219578_s_atMedullaOblongata26.05011.800Details
BioGPS Gene Atlas219578_s_atOccipitalLobe13.75011.800Details
BioGPS Gene Atlas219578_s_atOlfactoryBulb19.70011.800Details
BioGPS Gene Atlas219578_s_atOvary3.40011.800Details
BioGPS Gene Atlas219578_s_atPancreas3.95011.800Details
BioGPS Gene Atlas219578_s_atPancreaticIslet6.70011.800Details
BioGPS Gene Atlas219578_s_atParietalLobe13.55011.800Details
BioGPS Gene Atlas219578_s_atPituitary55.35011.800Details
BioGPS Gene Atlas219578_s_atPlacenta5.05011.800Details
BioGPS Gene Atlas219578_s_atPons7.95011.800Details
BioGPS Gene Atlas219578_s_atPrefrontalCortex76.30011.800Details
BioGPS Gene Atlas219578_s_atProstate5.85011.800Details
BioGPS Gene Atlas219578_s_atSalivarygland3.25011.800Details
BioGPS Gene Atlas219578_s_atSkeletalMuscle5.65011.800Details
BioGPS Gene Atlas219578_s_atSkin3.85011.800Details
BioGPS Gene Atlas219578_s_atSmoothMuscle5.95011.800Details
BioGPS Gene Atlas219578_s_atSpinalcord14.20011.800Details
BioGPS Gene Atlas219578_s_atSubthalamicNucleus7.75011.800Details
BioGPS Gene Atlas219578_s_atSuperiorCervicalGanglion5.60011.800Details
BioGPS Gene Atlas219578_s_atTemporalLobe9.45011.800Details
BioGPS Gene Atlas219578_s_atTestis144.35011.800Details
BioGPS Gene Atlas219578_s_atTestisGermCell27.30011.800Details
BioGPS Gene Atlas219578_s_atTestisIntersitial9.05011.800Details
BioGPS Gene Atlas219578_s_atTestisLeydigCell6.35011.800Details
BioGPS Gene Atlas219578_s_atTestisSeminiferousTubule43.55011.800Details
BioGPS Gene Atlas219578_s_atThalamus7.70011.800Details
BioGPS Gene Atlas219578_s_atThymus3.85011.800Details
BioGPS Gene Atlas219578_s_atThyroid6.00011.800Details
BioGPS Gene Atlas219578_s_atTongue4.90011.800Details
BioGPS Gene Atlas219578_s_atTonsil4.80011.800Details
BioGPS Gene Atlas219578_s_atTrachea4.10011.800Details
BioGPS Gene Atlas219578_s_atTrigeminalGanglion5.45011.800Details
BioGPS Gene Atlas219578_s_atUterus4.85011.800Details
BioGPS Gene Atlas219578_s_atUterusCorpus4.40011.800Details
BioGPS Gene Atlas219578_s_atWholeBlood5.30011.800Details
BioGPS Gene Atlas219578_s_atWholebrain68.85011.800Details
BioGPS Gene Atlas219578_s_atcolon4.70011.800Details
BioGPS Gene Atlas219578_s_atpineal_day6.00011.800Details
BioGPS Gene Atlas219578_s_atpineal_night5.80011.800Details
BioGPS Gene Atlas219578_s_atretina24.37511.800Details
BioGPS Gene Atlas219578_s_atsmall_intestine4.65011.800Details
BioGPS NCI60219578_s_at78621.15685.750Details
BioGPS NCI60219578_s_atA172450.14585.750Details
BioGPS NCI60219578_s_atA2049.28485.750Details
BioGPS NCI60219578_s_atA361204.76285.750Details
BioGPS NCI60219578_s_atA49848.54285.750Details
BioGPS NCI60219578_s_atA54911.49485.750Details
BioGPS NCI60219578_s_atACC39.71585.750Details
BioGPS NCI60219578_s_atACHN10.03085.750Details
BioGPS NCI60219578_s_atALVA319.75285.750Details
BioGPS NCI60219578_s_atCAKI115.93385.750Details
BioGPS NCI60219578_s_atCCRT CEM9.89685.750Details
BioGPS NCI60219578_s_atCOLO2059.43885.750Details
BioGPS NCI60219578_s_atDLD19.35685.750Details
BioGPS NCI60219578_s_atDU1459.15085.750Details
BioGPS NCI60219578_s_atEKVX8.33685.750Details
BioGPS NCI60219578_s_atGM13314.93685.750Details
BioGPS NCI60219578_s_atGM160029.82585.750Details
BioGPS NCI60219578_s_atGM231310.24385.750Details
BioGPS NCI60219578_s_atGM23459.92885.750Details
BioGPS NCI60219578_s_atGM249346.01785.750Details
BioGPS NCI60219578_s_atGM9741.67985.750Details
BioGPS NCI60219578_s_atHCC29986.30385.750Details
BioGPS NCI60219578_s_atHCT1168.53985.750Details
BioGPS NCI60219578_s_atHCT158.12885.750Details
BioGPS NCI60219578_s_atHEK 293 T-rex23.73985.750Details
BioGPS NCI60219578_s_atHEK 293T9.43885.750Details
BioGPS NCI60219578_s_atHEK29369.29785.750Details
BioGPS NCI60219578_s_atHELA9.68485.750Details
BioGPS NCI60219578_s_atHEPG28.42885.750Details
BioGPS NCI60219578_s_atHL609.53085.750Details
BioGPS NCI60219578_s_atHOP6250.10085.750Details
BioGPS NCI60219578_s_atHOP929.14185.750Details
BioGPS NCI60219578_s_atHS578T9.33585.750Details
BioGPS NCI60219578_s_atHSG9.24985.750Details
BioGPS NCI60219578_s_atHT10809.43385.750Details
BioGPS NCI60219578_s_atHT299.21485.750Details
BioGPS NCI60219578_s_atIGROV18.98485.750Details
BioGPS NCI60219578_s_atIOSE809.52785.750Details
BioGPS NCI60219578_s_atJURKAT9.44585.750Details
BioGPS NCI60219578_s_atK56242.62285.750Details
BioGPS NCI60219578_s_atKM129.63885.750Details
BioGPS NCI60219578_s_atLN187.87185.750Details
BioGPS NCI60219578_s_atLNCAP9.26085.750Details
BioGPS NCI60219578_s_atLOX IMVI9.29285.750Details
BioGPS NCI60219578_s_atM1483.05685.750Details
BioGPS NCI60219578_s_atMALME 3M195.43285.750Details
BioGPS NCI60219578_s_atMCF78.28785.750Details
BioGPS NCI60219578_s_atMD MB2319.51685.750Details
BioGPS NCI60219578_s_atMDA MB43511.74885.750Details
BioGPS NCI60219578_s_atMOLT48.96885.750Details
BioGPS NCI60219578_s_atNCI 4609.65585.750Details
BioGPS NCI60219578_s_atNCI H22694.38285.750Details
BioGPS NCI60219578_s_atNCI H23106.43385.750Details
BioGPS NCI60219578_s_atNCI H322M9.48585.750Details
BioGPS NCI60219578_s_atNCVADR RES78.86685.750Details
BioGPS NCI60219578_s_atOVCAR39.66985.750Details
BioGPS NCI60219578_s_atOVCAR48.42185.750Details
BioGPS NCI60219578_s_atOVCAR59.35085.750Details
BioGPS NCI60219578_s_atOVCAR838.17885.750Details
BioGPS NCI60219578_s_atPANC167.17585.750Details
BioGPS NCI60219578_s_atRL79.44185.750Details
BioGPS NCI60219578_s_atRPMI 82269.54385.750Details
BioGPS NCI60219578_s_atRS118469.03485.750Details
BioGPS NCI60219578_s_atRXF39344.66985.750Details
BioGPS NCI60219578_s_atSAOS29.57685.750Details
BioGPS NCI60219578_s_atSF2689.46685.750Details
BioGPS NCI60219578_s_atSF2959.35385.750Details
BioGPS NCI60219578_s_atSF539115.35285.750Details
BioGPS NCI60219578_s_atSHSYSY+RA9.34485.750Details
BioGPS NCI60219578_s_atSHSYSY-RA9.38685.750Details
BioGPS NCI60219578_s_atSKMEL287.63185.750Details
BioGPS NCI60219578_s_atSKMEL28126.74385.750Details
BioGPS NCI60219578_s_atSKMEL585.06785.750Details
BioGPS NCI60219578_s_atSKOV39.58685.750Details
BioGPS NCI60219578_s_atSN12C9.24385.750Details
BioGPS NCI60219578_s_atSNB199.31785.750Details
BioGPS NCI60219578_s_atSNB7514.37385.750Details
BioGPS NCI60219578_s_atSR9.55985.750Details
BioGPS NCI60219578_s_atSW6209.47585.750Details
BioGPS NCI60219578_s_atT249.53085.750Details
BioGPS NCI60219578_s_atT3M49.64485.750Details
BioGPS NCI60219578_s_atTK1016.38985.750Details
BioGPS NCI60219578_s_atU118553.27985.750Details
BioGPS NCI60219578_s_atU138496.24185.750Details
BioGPS NCI60219578_s_atU20S50.98285.750Details
BioGPS NCI60219578_s_atU2519.20185.750Details
BioGPS NCI60219578_s_atU871474.24385.750Details
BioGPS NCI60219578_s_atUACC257532.46985.750Details
BioGPS NCI60219578_s_atUACC629.39585.750Details
BioGPS NCI60219578_s_atUO318.12085.750Details
BioGPS NCI60219578_s_atZR75_18.81085.750Details
BioGPS NCI60219578_s_atastrocytes9.30385.750Details
BioGPS NCI60219578_s_athuh-79.79385.750Details