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Gene ID: 57094 | CPA6 Antibody Resource


CPA6 Antibody Resource
Gene Full Name: 
carboxypeptidase A6
Uniprot: 
Q8N4T0
Protein Name: 
carboxypeptidase A6
Nucleotide: 
NM_020361
Alias: 
CPAH;ETL5;FEB11;
Ensembl: 
ENSG00000165078
Location: 
8q13.2
HPRD: 
09891
NCBI Gene: 
57094
MIM: 
609562

Summary: 
The protein encoded by this gene belongs to the family of carboxypeptidases, which catalyze the release of C-terminal amino acid, and have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Polymorphic variants and a reciprocal translocation t(6;8)(q26;q13) involving this gene, have been associated with Duane retraction syndrome.[provided by RefSeq, Sep 2010]
Function: 
May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II.
Subcellular location: 
Secreted › extracellular space › extracellular matrix .
PTM: 
Cleavage on pair of basic residues;
Disease: 
A chromosomal aberration involving CPA6 was found in a patient with Duane retraction syndrome. Translocation t(6;8)(q26;q13).Epilepsy, familial temporal lobe, 5 (ETL5) [MIM:614417]: A focal form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe. Seizures are usually accompanied by sensory symptoms, most often auditory in nature. Note: The disease is caused by mutations affecting the gene represented in this entry. Febrile seizures, familial, 11 (FEB11) [MIM:614418]: Seizures associated with febrile episodes in childhood without any evidence of intracranial infection or defined pathologic or traumatic cause. It is a common condition, affecting 2-5% of children aged 3 months to 5 years. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP57397_P050 CPA6 antibody - middle region (ARP57397_P050) Polyclonal Bovine, Horse, Mouse, Pig, Rabbit, Rat WB 50ug $289 Details
Polyclonal Antibody ARP57396_P050 CPA6 Antibody (ARP57396_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details
Polyclonal Antibody OAAB07573 CPA6 antibody - center region (OAAB07573) Human WB 400ul $289 Details

Show all CPA6 antibodies


Product Images
CPA6 antibody - middle region (ARP57397_P050) in Human 721_B cells using Western Blot

Sample Type: Human 721_B

CPA6 antibody - center region (OAAB07573) in NCI-H460 cells using Western Blot

Sample Type: NCI-H460


CPA6 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP57397 African clawed frog CPA6 antibody; Xenopus laevis CPA6 antibody Q8AVS2 86.0%
ARP57396 African clawed frog CPA6 antibody; Xenopus laevis CPA6 antibody Q8AVS2 79.0%
ARP57396 African elephant CPA6 antibody; Loxodonta africana CPA6 antibody G3T765 100.0%
ARP57397 African elephant CPA6 antibody; Loxodonta africana CPA6 antibody G3T765 100.0%
ARP57396 Cat CPA6 antibody; Felis catus CPA6 antibody M3W7E0 100.0%
ARP57397 Cat CPA6 antibody; Felis catus CPA6 antibody M3W7E0 93.0%
ARP41981 Cat CPA6 antibody; Felis catus CPA6 antibody M3W7E0 83.0%
ARP57396 Chicken CPA6 antibody; Gallus gallus CPA6 antibody F1N8X0 100.0%
ARP57397 Chicken CPA6 antibody; Gallus gallus CPA6 antibody F1N8X0 100.0%
ARP57396 Chimpanzee CPA6 antibody; Pan troglodytes CPA6 antibody H2QW97 100.0%
ARP57397 Chimpanzee CPA6 antibody; Pan troglodytes CPA6 antibody H2QW97 100.0%
ARP57396 Chinese softshell turtle CPA6 antibody; Pelodiscus sinensis CPA6 antibody K7GFN9 100.0%
ARP57397 Chinese softshell turtle CPA6 antibody; Pelodiscus sinensis CPA6 antibody K7GFN9 100.0%
ARP57396 Collared flycatcher CPA6 antibody; Ficedula albicollis CPA6 antibody U3JS40 100.0%
ARP57397 Collared flycatcher CPA6 antibody; Ficedula albicollis CPA6 antibody U3JS40 100.0%
ARP57396 Common turkey CPA6 antibody; Meleagris gallopavo CPA6 antibody G1NFQ6 100.0%
ARP57397 Common turkey CPA6 antibody; Meleagris gallopavo CPA6 antibody G1NFQ6 100.0%
ARP57396 Dog CPA6 antibody; Canis familiaris CPA6 antibody F1Q4J2 100.0%
ARP57397 Dog CPA6 antibody; Canis familiaris CPA6 antibody F1Q4J2 93.0%
ARP41981 Dog CPA6 antibody; Canis familiaris CPA6 antibody F1Q4J2 83.0%
ARP57397 Domestic duck CPA6 antibody; Anas platyrhynchos CPA6 antibody U3I5D8 100.0%
ARP57396 Domestic duck CPA6 antibody; Anas platyrhynchos CPA6 antibody U3I5D8 93.0%
ARP57396 Duckbill platypus CPA6 antibody; Ornithorhynchus anatinus CPA6 antibody F7E698 100.0%
ARP57397 Duckbill platypus CPA6 antibody; Ornithorhynchus anatinus CPA6 antibody F7E698 100.0%
ARP57396 European domestic ferret CPA6 antibody; Mustela putorius furo CPA6 antibody M3XU74 100.0%
ARP57397 European domestic ferret CPA6 antibody; Mustela putorius furo CPA6 antibody M3XU74 93.0%
ARP41981 European domestic ferret CPA6 antibody; Mustela putorius furo CPA6 antibody M3XU74 83.0%
ARP57396 European seabass CPA6 antibody; Dicentrarchus labrax CPA6 antibody E6ZIP5 100.0%
ARP57397 European seabass CPA6 antibody; Dicentrarchus labrax CPA6 antibody E6ZIP5 100.0%
ARP57396 Gray short-tailed opossum CPA6 antibody; Monodelphis domestica CPA6 antibody F7EVA7 100.0%
ARP57397 Gray short-tailed opossum CPA6 antibody; Monodelphis domestica CPA6 antibody F7EVA7 100.0%
ARP57396 Green anole CPA6 antibody; Anolis carolinensis CPA6 antibody G1KSF0 100.0%
ARP57397 Green anole CPA6 antibody; Anolis carolinensis CPA6 antibody G1KSF0 100.0%
ARP57396 Horse CPA6 antibody; Equus caballus CPA6 antibody F6ZC58 100.0%
ARP57396 Horse CPA6 antibody; Equus caballus CPA6 antibody F6TB63 100.0%
ARP57397 Horse CPA6 antibody; Equus caballus CPA6 antibody F6ZC58 93.0%
ARP57397 Horse CPA6 antibody; Equus caballus CPA6 antibody F6TB63 93.0%
ARP41981 Horse CPA6 antibody; Equus caballus CPA6 antibody F6TB63 83.0%
ARP41981 Horse CPA6 antibody; Equus caballus CPA6 antibody F6ZC58 83.0%
ARP57397 Human CPA6 antibody; Homo sapiens CPA6 antibody Q8N4T0-3 100.0%
ARP57396 Human CPA6 antibody; Homo sapiens CPA6 antibody Q8N4T0 100.0%
ARP57397 Human CPA6 antibody; Homo sapiens CPA6 antibody Q8N4T0 100.0%
ARP57396 Mouse CPA6 antibody; Mus musculus CPA6 antibody Q0VDR2 100.0%
ARP57397 Mouse CPA6 antibody; Mus musculus CPA6 antibody Q0VDR2 100.0%
ARP57396 Mouse CPA6 antibody; Mus musculus CPA6 antibody Q5U901-2 100.0%
ARP57397 Mouse CPA6 antibody; Mus musculus CPA6 antibody Q5U901-2 100.0%
ARP57396 Mouse CPA6 antibody; Mus musculus CPA6 antibody Q5U901 100.0%
ARP57397 Mouse CPA6 antibody; Mus musculus CPA6 antibody Q5U901 100.0%
ARP57396 Northern white-cheeked gibbon CPA6 antibody; Nomascus leucogenys CPA6 antibody G1RJR3 100.0%
ARP57397 Northern white-cheeked gibbon CPA6 antibody; Nomascus leucogenys CPA6 antibody G1RJR3 100.0%
ARP57396 Pig CPA6 antibody; Sus scrofa CPA6 antibody K7GM46 100.0%
ARP57396 Pig CPA6 antibody; Sus scrofa CPA6 antibody F1RU03 100.0%
ARP57397 Pig CPA6 antibody; Sus scrofa CPA6 antibody K7GM46 92.0%
ARP57397 Pig CPA6 antibody; Sus scrofa CPA6 antibody F1RU03 92.0%
ARP41981 Pig CPA6 antibody; Sus scrofa CPA6 antibody K7GM46 83.0%
ARP41981 Pig CPA6 antibody; Sus scrofa CPA6 antibody F1RU03 83.0%
ARP57396 Rabbit CPA6 antibody; Oryctolagus cuniculus CPA6 antibody G1SNY7 100.0%
ARP57397 Rabbit CPA6 antibody; Oryctolagus cuniculus CPA6 antibody G1SNY7 93.0%
ARP57397 Rat CPA6 antibody; Rattus norvegicus CPA6 antibody F1M4P0 93.0%
ARP57397 Rhesus macaque CPA6 antibody; Macaca mulatta CPA6 antibody F6VMK8 100.0%
ARP57396 Rhesus macaque CPA6 antibody; Macaca mulatta CPA6 antibody F6VMP4 100.0%
ARP57397 Rhesus macaque CPA6 antibody; Macaca mulatta CPA6 antibody F6VMP4 100.0%
ARP57396 Small-eared galago CPA6 antibody; Otolemur garnettii CPA6 antibody H0WTT9 100.0%
ARP57397 Small-eared galago CPA6 antibody; Otolemur garnettii CPA6 antibody H0WTT9 100.0%
ARP57396 Spotted green pufferfish CPA6 antibody; Tetraodon nigroviridis CPA6 antibody H3CXM3 93.0%
ARP57397 Spotted green pufferfish CPA6 antibody; Tetraodon nigroviridis CPA6 antibody H3CXM3 93.0%
ARP41981 Spotted green pufferfish CPA6 antibody; Tetraodon nigroviridis CPA6 antibody H3CXM3 83.0%
ARP57396 Sumatran orangutan CPA6 antibody; Pongo abelii CPA6 antibody H2PQI2 100.0%
ARP57397 Sumatran orangutan CPA6 antibody; Pongo abelii CPA6 antibody H2PQI2 100.0%
ARP57397 Tasmanian devil CPA6 antibody; Sarcophilus harrisii CPA6 antibody G3WKZ2 100.0%
ARP57396 Tasmanian devil CPA6 antibody; Sarcophilus harrisii CPA6 antibody G3WKZ2 93.0%
ARP57397 Western clawed frog CPA6 antibody; Xenopus tropicalis CPA6 antibody B0BM52 86.0%
ARP57397 Western clawed frog CPA6 antibody; Xenopus tropicalis CPA6 antibody F6R9Z7 86.0%
ARP57397 Western clawed frog CPA6 antibody; Xenopus tropicalis CPA6 antibody F6SG10 86.0%
ARP57396 Western clawed frog CPA6 antibody; Xenopus tropicalis CPA6 antibody B0BM52 79.0%
ARP57396 Western clawed frog CPA6 antibody; Xenopus tropicalis CPA6 antibody F6R9Z7 79.0%
ARP57396 Western clawed frog CPA6 antibody; Xenopus tropicalis CPA6 antibody F6SG10 79.0%
ARP57396 White-tufted-ear marmoset CPA6 antibody; Callithrix jacchus CPA6 antibody F7IF65 100.0%
ARP57397 White-tufted-ear marmoset CPA6 antibody; Callithrix jacchus CPA6 antibody F7IF65 100.0%
ARP57397 White-tufted-ear marmoset CPA6 antibody; Callithrix jacchus CPA6 antibody F7IHG9 100.0%
ARP57396 Zebra finch CPA6 antibody; Taeniopygia guttata CPA6 antibody H0ZMC2 100.0%
ARP57397 Zebra finch CPA6 antibody; Taeniopygia guttata CPA6 antibody H0ZMC2 100.0%
ARP57396 Zebrafish CPA6 antibody; Danio rerio CPA6 antibody E7F2H8 100.0%
ARP57397 Zebrafish CPA6 antibody; Danio rerio CPA6 antibody E7F2H8 100.0%

Tissue & Cell Line Gene Expression Data