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Gene ID: 1340 | COX6B1 Antibody Resource


COX6B1 Antibody Resource
Gene Full Name: 
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
Uniprot: 
P14854
Protein Name: 
cytochrome c oxidase subunit 6B1
Nucleotide: 
NM_001863
Alias: 
COXG;COX6B;COXVIb1;
Ensembl: 
ENSG00000126267
Location: 
19q13.1
HPRD: 
00493
NCBI Gene: 
1340
MIM: 
124089

Summary: 
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively. [provided by RefSeq, Jan 2010]
Function: 
Connects the two COX monomers into the physiological dimeric form .
Subcellular location: 
Mitochondrion intermembrane space.
PTM: 
Acetylation;
Disease: 
Mitochondrial complex IV deficiency (MT-C4D) [MIM:220110]: A disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs. Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness, exercise intolerance, developmental delay, delayed motor development and mental retardation. Some affected individuals manifest a fatal hypertrophic cardiomyopathy resulting in neonatal death. A subset of patients manifest Leigh syndrome. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP66777_P050 COX6B1 Antibody - N-terminal region (ARP66777_P050) Human WB 50ug $289 Details
Polyclonal Antibody OAAB08597 COX6B1 antibody - C - terminal region (OAAB08597) Human WB, IHC 400ul $289 Details
Polyclonal Antibody OAGA00657 COX6B1 antibody (OAGA00657) Polyclonal Human ICC/IF, IHC (Formalin-fixed paraffin-embedded sections), WB 100 ul $340 Details

Show all COX6B1 antibodies


Product Images
COX6B1 Antibody - N-terminal region (ARP66777_P050) in Human OVCAR-3 cells using Western Blot

Sample Type: Human OVCAR-3

COX6B1 antibody - C - terminal region (OAAB08597) in Human cells using Western Blot

Sample Type: Human

COX6B1 antibody - C - terminal region (OAAB08597) in Human Kidney cells using Immunohistochemistry

Sample Type: Human Kidney


COX6B1 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP66777 African clawed frog COX6B1 antibody; Xenopus laevis COX6B1 antibody Q6NTR9 79.0%
ARP66777 African clawed frog COX6B1 antibody; Xenopus laevis COX6B1 antibody A2RVB6 79.0%
ARP66777 Bovine COX6B1 antibody; Bos taurus COX6B1 antibody P00429 100.0%
ARP66777 Bovine COX6B1 antibody; Bos taurus COX6B1 antibody F1N2E5 93.0%
ARP66777 Chimpanzee COX6B1 antibody; Pan troglodytes COX6B1 antibody K7CTL6 100.0%
ARP66777 Chinese softshell turtle COX6B1 antibody; Pelodiscus sinensis COX6B1 antibody K7FAT9 100.0%
ARP66777 Crab-eating macaque COX6B1 antibody; Macaca fascicularis COX6B1 antibody Q4R374 100.0%
ARP66777 Duckbill platypus COX6B1 antibody; Ornithorhynchus anatinus COX6B1 antibody F6R2G8 100.0%
ARP66777 European domestic ferret COX6B1 antibody; Mustela putorius furo COX6B1 antibody M3Y4F3 100.0%
ARP66777 Giant panda COX6B1 antibody; Ailuropoda melanoleuca COX6B1 antibody E5L4Y6 100.0%
ARP66777 Gray short-tailed opossum COX6B1 antibody; Monodelphis domestica COX6B1 antibody F6RS65 100.0%
ARP66777 Honeybee COX6B1 antibody; Apis mellifera COX6B1 antibody H9KLW7 79.0%
ARP66777 Horse COX6B1 antibody; Equus caballus COX6B1 antibody F6SD71 100.0%
ARP66777 Human COX6B1 antibody; Homo sapiens COX6B1 antibody K7EQD3 100.0%
ARP66777 Human COX6B1 antibody; Homo sapiens COX6B1 antibody P14854 100.0%
ARP66777 Leschenault's rousette COX6B1 antibody; Rousettus leschenaultii COX6B1 antibody D7NY83 100.0%
ARP66777 Lesser asiatic yellow bat COX6B1 antibody; Scotophilus kuhlii COX6B1 antibody D7NY80 100.0%
ARP66777 Mouse COX6B1 antibody; Mus musculus COX6B1 antibody P56391 93.0%
ARP66777 Parasitic wasp COX6B1 antibody; Nasonia vitripennis COX6B1 antibody K7IXT2 86.0%
ARP52704 Parasitic wasp COX6B1 antibody; Nasonia vitripennis COX6B1 antibody K7IXT2 85.0%
ARP66777 Philippine tarsier COX6B1 antibody; Tarsius syrichta COX6B1 antibody Q7YRK6 100.0%
ARP66777 Rat COX6B1 antibody; Rattus norvegicus COX6B1 antibody D3ZD09 93.0%
ARP66777 Rhesus macaque COX6B1 antibody; Macaca mulatta COX6B1 antibody Q53CG4 100.0%
ARP66777 Schreibers's long-fingered bat COX6B1 antibody; Miniopterus schreibersii COX6B1 antibody D7NY81 100.0%
ARP66777 Small-eared galago COX6B1 antibody; Otolemur garnettii COX6B1 antibody H0WPA2 100.0%
ARP66777 Sumatran orangutan COX6B1 antibody; Pongo abelii COX6B1 antibody Q5RCT0 100.0%
ARP66777 Tasmanian devil COX6B1 antibody; Sarcophilus harrisii COX6B1 antibody G3W4Y6 100.0%
ARP66777 Thirteen-lined ground squirrel COX6B1 antibody; Spermophilus tridecemlineatus COX6B1 antibody I3N6P0 100.0%
ARP66777 Western clawed frog COX6B1 antibody; Xenopus tropicalis COX6B1 antibody Q6DEQ9 79.0%
ARP66777 White-tufted-ear marmoset COX6B1 antibody; Callithrix jacchus COX6B1 antibody U3BCZ9 100.0%
ARP66777 White-tufted-ear marmoset COX6B1 antibody; Callithrix jacchus COX6B1 antibody F7DGE7 100.0%
ARP66777 White-tufted-ear marmoset COX6B1 antibody; Callithrix jacchus COX6B1 antibody F7DXQ1 100.0%
ARP66777 Zebrafish COX6B1 antibody; Danio rerio COX6B1 antibody Q6DH63 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas201441_at721_B_lymphoblasts2132.150732.390Details
BioGPS Gene Atlas201441_atAdipocyte811.200732.390Details
BioGPS Gene Atlas201441_atAdrenalCortex371.500732.390Details
BioGPS Gene Atlas201441_atAdrenalgland444.400732.390Details
BioGPS Gene Atlas201441_atAmygdala542.800732.390Details
BioGPS Gene Atlas201441_atAppendix196.150732.390Details
BioGPS Gene Atlas201441_atAtrioventricularNode48.600732.390Details
BioGPS Gene Atlas201441_atBDCA4+_DentriticCells1478.200732.390Details
BioGPS Gene Atlas201441_atBonemarrow620.900732.390Details
BioGPS Gene Atlas201441_atBronchialEpithelialCells1152.750732.390Details
BioGPS Gene Atlas201441_atCD105+_Endothelial1075.550732.390Details
BioGPS Gene Atlas201441_atCD14+_Monocytes1475.650732.390Details
BioGPS Gene Atlas201441_atCD19+_BCells(neg._sel.)1032.850732.390Details
BioGPS Gene Atlas201441_atCD33+_Myeloid1046.200732.390Details
BioGPS Gene Atlas201441_atCD34+1530.200732.390Details
BioGPS Gene Atlas201441_atCD4+_Tcells828.200732.390Details
BioGPS Gene Atlas201441_atCD56+_NKCells1088.400732.390Details
BioGPS Gene Atlas201441_atCD71+_EarlyErythroid1202.400732.390Details
BioGPS Gene Atlas201441_atCD8+_Tcells853.600732.390Details
BioGPS Gene Atlas201441_atCardiacMyocytes482.550732.390Details
BioGPS Gene Atlas201441_atCaudatenucleus512.400732.390Details
BioGPS Gene Atlas201441_atCerebellum473.050732.390Details
BioGPS Gene Atlas201441_atCerebellumPeduncles890.050732.390Details
BioGPS Gene Atlas201441_atCiliaryGanglion92.300732.390Details
BioGPS Gene Atlas201441_atCingulateCortex777.800732.390Details
BioGPS Gene Atlas201441_atColorectaladenocarcinoma311.900732.390Details
BioGPS Gene Atlas201441_atDorsalRootGanglion108.600732.390Details
BioGPS Gene Atlas201441_atFetalThyroid826.200732.390Details
BioGPS Gene Atlas201441_atFetalbrain409.900732.390Details
BioGPS Gene Atlas201441_atFetalliver349.650732.390Details
BioGPS Gene Atlas201441_atFetallung514.200732.390Details
BioGPS Gene Atlas201441_atGlobusPallidus395.050732.390Details
BioGPS Gene Atlas201441_atHeart3568.650732.390Details
BioGPS Gene Atlas201441_atHypothalamus1078.950732.390Details
BioGPS Gene Atlas201441_atKidney623.800732.390Details
BioGPS Gene Atlas201441_atLeukemia_chronicMyelogenousK-5621274.500732.390Details
BioGPS Gene Atlas201441_atLeukemia_promyelocytic-HL-60863.400732.390Details
BioGPS Gene Atlas201441_atLeukemialymphoblastic(MOLT-4)719.400732.390Details
BioGPS Gene Atlas201441_atLiver627.750732.390Details
BioGPS Gene Atlas201441_atLung621.200732.390Details
BioGPS Gene Atlas201441_atLymphnode420.500732.390Details
BioGPS Gene Atlas201441_atLymphoma_burkitts(Daudi)1261.950732.390Details
BioGPS Gene Atlas201441_atLymphoma_burkitts(Raji)742.200732.390Details
BioGPS Gene Atlas201441_atMedullaOblongata634.700732.390Details
BioGPS Gene Atlas201441_atOccipitalLobe674.900732.390Details
BioGPS Gene Atlas201441_atOlfactoryBulb360.000732.390Details
BioGPS Gene Atlas201441_atOvary204.900732.390Details
BioGPS Gene Atlas201441_atPancreas481.650732.390Details
BioGPS Gene Atlas201441_atPancreaticIslet518.700732.390Details
BioGPS Gene Atlas201441_atParietalLobe643.450732.390Details
BioGPS Gene Atlas201441_atPituitary605.800732.390Details
BioGPS Gene Atlas201441_atPlacenta417.300732.390Details
BioGPS Gene Atlas201441_atPons524.750732.390Details
BioGPS Gene Atlas201441_atPrefrontalCortex1194.900732.390Details
BioGPS Gene Atlas201441_atProstate636.250732.390Details
BioGPS Gene Atlas201441_atSalivarygland445.900732.390Details
BioGPS Gene Atlas201441_atSkeletalMuscle1088.100732.390Details
BioGPS Gene Atlas201441_atSkin97.150732.390Details
BioGPS Gene Atlas201441_atSmoothMuscle885.500732.390Details
BioGPS Gene Atlas201441_atSpinalcord618.200732.390Details
BioGPS Gene Atlas201441_atSubthalamicNucleus578.600732.390Details
BioGPS Gene Atlas201441_atSuperiorCervicalGanglion21.900732.390Details
BioGPS Gene Atlas201441_atTemporalLobe882.250732.390Details
BioGPS Gene Atlas201441_atTestis411.350732.390Details
BioGPS Gene Atlas201441_atTestisGermCell321.950732.390Details
BioGPS Gene Atlas201441_atTestisIntersitial265.200732.390Details
BioGPS Gene Atlas201441_atTestisLeydigCell192.200732.390Details
BioGPS Gene Atlas201441_atTestisSeminiferousTubule191.250732.390Details
BioGPS Gene Atlas201441_atThalamus1022.200732.390Details
BioGPS Gene Atlas201441_atThymus788.550732.390Details
BioGPS Gene Atlas201441_atThyroid562.000732.390Details
BioGPS Gene Atlas201441_atTongue830.850732.390Details
BioGPS Gene Atlas201441_atTonsil622.900732.390Details
BioGPS Gene Atlas201441_atTrachea315.250732.390Details
BioGPS Gene Atlas201441_atTrigeminalGanglion91.850732.390Details
BioGPS Gene Atlas201441_atUterus222.200732.390Details
BioGPS Gene Atlas201441_atUterusCorpus240.500732.390Details
BioGPS Gene Atlas201441_atWholeBlood1194.800732.390Details
BioGPS Gene Atlas201441_atWholebrain1376.200732.390Details
BioGPS Gene Atlas201441_atcolon999.550732.390Details
BioGPS Gene Atlas201441_atpineal_day1116.500732.390Details
BioGPS Gene Atlas201441_atpineal_night893.020732.390Details
BioGPS Gene Atlas201441_atretina706.200732.390Details
BioGPS Gene Atlas201441_atsmall_intestine973.100732.390Details
BioGPS NCI60201441_at7863215.8364216.600Details
BioGPS NCI60201441_atA1722663.3184216.600Details
BioGPS NCI60201441_atA2044354.1974216.600Details
BioGPS NCI60201441_atA3617400.0084216.600Details
BioGPS NCI60201441_atA4984074.6934216.600Details
BioGPS NCI60201441_atA5497770.4054216.600Details
BioGPS NCI60201441_atACC32671.6804216.600Details
BioGPS NCI60201441_atACHN3140.6134216.600Details
BioGPS NCI60201441_atALVA315148.6954216.600Details
BioGPS NCI60201441_atCAKI14410.5384216.600Details
BioGPS NCI60201441_atCCRT CEM1891.1774216.600Details
BioGPS NCI60201441_atCOLO2056805.1924216.600Details
BioGPS NCI60201441_atDLD14513.7974216.600Details
BioGPS NCI60201441_atDU1454408.2704216.600Details
BioGPS NCI60201441_atEKVX5917.6084216.600Details
BioGPS NCI60201441_atGM1332434.1044216.600Details
BioGPS NCI60201441_atGM16002885.6854216.600Details
BioGPS NCI60201441_atGM23132388.3284216.600Details
BioGPS NCI60201441_atGM23453542.5734216.600Details
BioGPS NCI60201441_atGM24932962.7834216.600Details
BioGPS NCI60201441_atGM973016.5804216.600Details
BioGPS NCI60201441_atHCC29984451.7364216.600Details
BioGPS NCI60201441_atHCT1167350.2824216.600Details
BioGPS NCI60201441_atHCT156709.0994216.600Details
BioGPS NCI60201441_atHEK 293 T-rex6744.4174216.600Details
BioGPS NCI60201441_atHEK 293T3066.1204216.600Details
BioGPS NCI60201441_atHEK2935501.1734216.600Details
BioGPS NCI60201441_atHELA6343.6354216.600Details
BioGPS NCI60201441_atHEPG24917.9474216.600Details
BioGPS NCI60201441_atHL603732.8044216.600Details
BioGPS NCI60201441_atHOP624197.5574216.600Details
BioGPS NCI60201441_atHOP925004.0034216.600Details
BioGPS NCI60201441_atHS578T2201.7604216.600Details
BioGPS NCI60201441_atHSG4947.1054216.600Details
BioGPS NCI60201441_atHT10805171.3954216.600Details
BioGPS NCI60201441_atHT294353.1814216.600Details
BioGPS NCI60201441_atIGROV14484.1374216.600Details
BioGPS NCI60201441_atIOSE803020.7484216.600Details
BioGPS NCI60201441_atJURKAT3195.3044216.600Details
BioGPS NCI60201441_atK5625124.6444216.600Details
BioGPS NCI60201441_atKM126425.8254216.600Details
BioGPS NCI60201441_atLN183801.4354216.600Details
BioGPS NCI60201441_atLNCAP4757.7904216.600Details
BioGPS NCI60201441_atLOX IMVI4375.2394216.600Details
BioGPS NCI60201441_atM144683.2904216.600Details
BioGPS NCI60201441_atMALME 3M1572.5394216.600Details
BioGPS NCI60201441_atMCF75900.7674216.600Details
BioGPS NCI60201441_atMD MB2314009.5714216.600Details
BioGPS NCI60201441_atMDA MB4358026.0904216.600Details
BioGPS NCI60201441_atMOLT46046.6824216.600Details
BioGPS NCI60201441_atNCI 4604359.9064216.600Details
BioGPS NCI60201441_atNCI H2264055.7394216.600Details
BioGPS NCI60201441_atNCI H232738.4964216.600Details
BioGPS NCI60201441_atNCI H322M3461.0024216.600Details
BioGPS NCI60201441_atNCVADR RES1900.8224216.600Details
BioGPS NCI60201441_atOVCAR33585.3274216.600Details
BioGPS NCI60201441_atOVCAR47916.6694216.600Details
BioGPS NCI60201441_atOVCAR53173.4224216.600Details
BioGPS NCI60201441_atOVCAR81915.8364216.600Details
BioGPS NCI60201441_atPANC17715.3814216.600Details
BioGPS NCI60201441_atRL74649.5924216.600Details
BioGPS NCI60201441_atRPMI 82263856.9164216.600Details
BioGPS NCI60201441_atRS118464899.7414216.600Details
BioGPS NCI60201441_atRXF3934065.9764216.600Details
BioGPS NCI60201441_atSAOS22450.3734216.600Details
BioGPS NCI60201441_atSF2682336.0934216.600Details
BioGPS NCI60201441_atSF2954126.6894216.600Details
BioGPS NCI60201441_atSF5395267.8024216.600Details
BioGPS NCI60201441_atSHSYSY+RA4273.7034216.600Details
BioGPS NCI60201441_atSHSYSY-RA3385.5944216.600Details
BioGPS NCI60201441_atSKMEL24089.1464216.600Details
BioGPS NCI60201441_atSKMEL285255.4574216.600Details
BioGPS NCI60201441_atSKMEL55565.5584216.600Details
BioGPS NCI60201441_atSKOV35099.0234216.600Details
BioGPS NCI60201441_atSN12C4607.3144216.600Details
BioGPS NCI60201441_atSNB197061.3284216.600Details
BioGPS NCI60201441_atSNB752376.9154216.600Details
BioGPS NCI60201441_atSR3818.3944216.600Details
BioGPS NCI60201441_atSW6205051.9104216.600Details
BioGPS NCI60201441_atT242752.4364216.600Details
BioGPS NCI60201441_atT3M42247.4314216.600Details
BioGPS NCI60201441_atTK103669.8824216.600Details
BioGPS NCI60201441_atU1184461.9204216.600Details
BioGPS NCI60201441_atU1383130.3784216.600Details
BioGPS NCI60201441_atU20S2163.9304216.600Details
BioGPS NCI60201441_atU2512832.0364216.600Details
BioGPS NCI60201441_atU874042.4234216.600Details
BioGPS NCI60201441_atUACC2573893.0054216.600Details
BioGPS NCI60201441_atUACC625709.4974216.600Details
BioGPS NCI60201441_atUO312229.0614216.600Details
BioGPS NCI60201441_atZR75_15331.6374216.600Details
BioGPS NCI60201441_atastrocytes1860.0654216.600Details
BioGPS NCI60201441_athuh-73482.2644216.600Details