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Gene ID: 84701 | COX4I2 Antibody Resource


COX4I2 Antibody Resource
Gene Full Name: 
cytochrome c oxidase subunit IV isoform 2 (lung)
Uniprot: 
Q96KJ9
Protein Name: 
cytochrome c oxidase subunit 4 isoform 2, mitochondrial
Nucleotide: 
XM_005260581
Alias: 
COX4;COX4B;COX4-2;COX4L2;COXIV-2;dJ857M17.2;
Ensembl: 
ENSG00000131055
Location: 
20q11.21
HPRD: 
12143
NCBI Gene: 
84701
MIM: 
607976

Summary: 
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008]
Function: 
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Subcellular location: 
Mitochondrion inner membrane.
PTM: 
Disulfide bond;
Disease: 
Exocrine pancreatic insufficiency dyserythropoietic anemia and calvarial hyperostosis (EPIDACH) [MIM:612714]: Patients present with pancreatic insufficiency, intestinal malabsorption, failure to thrive, and anemia soon after birth. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAEB01486 COX4I2 Antibody (OAEB01486) Bovine, Dog, Mouse, Rabbit WB 0.1mg $289 Details
Polyclonal Antibody ARP50090_P050 COX4I2 Antibody (ARP50090_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAF02931 COX4I2 Antibody (OAAF02931) Polyclonal Human, Mouse, Rat WB, IF, ELISA 100 ug $229 Details

Show all COX4I2 antibodies


Product Images
COX4I2 Antibody (OAAF02931) in COS7 cells using Immunofluorescence

Sample Type: COS7

COX4I2 Antibody (OAAF02931) in K562 cells using Western Blot

Sample Type: K562

COX4I2 Antibody (OAEB01486) in Humankeletal Muscle cells using Western Blot

Sample Type: Humankeletal Muscle


COX4I2 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP50090 Bovine COX4I2 antibody; Bos taurus COX4I2 antibody E1B8K7 92.0%
ARP50090 Cat COX4I2 antibody; Felis catus COX4I2 antibody M3WL40 85.0%
ARP50090 Chimpanzee COX4I2 antibody; Pan troglodytes COX4I2 antibody H2QK52 93.0%
ARP50090 Dog COX4I2 antibody; Canis familiaris COX4I2 antibody E2RB66 92.0%
ARP50090 European domestic ferret COX4I2 antibody; Mustela putorius furo COX4I2 antibody M3Z2I1 92.0%
ARP50090 Giant panda COX4I2 antibody; Ailuropoda melanoleuca COX4I2 antibody G1M528 92.0%
ARP50090 Horse COX4I2 antibody; Equus caballus COX4I2 antibody F7DTN7 85.0%
ARP50090 Human COX4I2 antibody; Homo sapiens COX4I2 antibody H6SG14 100.0%
ARP50090 Human COX4I2 antibody; Homo sapiens COX4I2 antibody Q96KJ9 100.0%
ARP50090 Indian short-nosed fruit bat COX4I2 antibody; Cynopterus sphinx COX4I2 antibody D7NY65 85.0%
ARP50090 Rabbit COX4I2 antibody; Oryctolagus cuniculus COX4I2 antibody G1U187 85.0%
ARP50090 Rhesus macaque COX4I2 antibody; Macaca mulatta COX4I2 antibody F7E0N8 86.0%
ARP50090 Small-eared galago COX4I2 antibody; Otolemur garnettii COX4I2 antibody H0X2C1 92.0%
ARP50090 Sumatran orangutan COX4I2 antibody; Pongo abelii COX4I2 antibody K7EW10 93.0%
ARP50090 White-tufted-ear marmoset COX4I2 antibody; Callithrix jacchus COX4I2 antibody F7IT30 93.0%
ARP50090 White-tufted-ear marmoset COX4I2 antibody; Callithrix jacchus COX4I2 antibody U3ES81 93.0%

Tissue & Cell Line Gene Expression Data