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Gene ID: 27235 | COQ2 Antibody Resource


COQ2 Antibody Resource
Gene Full Name: 
coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
Uniprot: 
Q96H96
Protein Name: 
4-hydroxybenzoate polyprenyltransferase, mitochondrial
Nucleotide: 
XM_005262926
Alias: 
MSA1;CL640;COQ10D1;
Ensembl: 
ENSG00000173085
Location: 
4q21.23
HPRD: 
13062
NCBI Gene: 
27235
MIM: 
609825

Summary: 
This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. [provided by RefSeq, Oct 2009]
Function: 
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB.
Subcellular location: 
Mitochondrion membrane; Multi-pass membrane protein Probable.
PTM: 
Disease: 
Coenzyme Q10 deficiency, primary, 1 (COQ10D1) [MIM:607426]: An autosomal recessive disorder with variable manifestations consistent with 5 major phenotypes. The phenotypes include an encephalomyopathic form with seizures and ataxia; a multisystem infantile form with encephalopathy, cardiomyopathy and renal failure; a predominantly cerebellar form with ataxia and cerebellar atrophy; Leigh syndrome with growth retardation; and an isolated myopathic form. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP47180_P050 COQ2 antibody - middle region (ARP47180_P050) Polyclonal Dog, Human, Pig WB 50ug $289 Details

Show all COQ2 antibodies


Product Images
COQ2 antibody - middle region (ARP47180_P050) in Human DU145 cells using Western Blot

Sample Type: Human DU145


COQ2 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP47180 Atlantic salmon COQ2 antibody; Salmo salar COQ2 antibody B5XEL1 79.0%
ARP47180 Cat COQ2 antibody; Felis catus COQ2 antibody M3WL09 93.0%
ARP47180 Chimpanzee COQ2 antibody; Pan troglodytes COQ2 antibody H2QPT4 100.0%
ARP47180 Chinese softshell turtle COQ2 antibody; Pelodiscus sinensis COQ2 antibody K7GEB5 79.0%
ARP47180 Dog COQ2 antibody; Canis familiaris COQ2 antibody E2QT06 93.0%
ARP47180 European domestic ferret COQ2 antibody; Mustela putorius furo COQ2 antibody M3YTC0 93.0%
ARP47180 Fission yeast COQ2 antibody; Schizosaccharomyces pombe COQ2 antibody Q10252 91.0%
ARP47180 Fruit fly COQ2 antibody; Drosophila pseudoobscura pseudoobscura COQ2 antibody Q298G6 93.0%
ARP47180 Fruit fly COQ2 antibody; Drosophila melanogaster COQ2 antibody Q9VHS7 93.0%
ARP47180 Gray short-tailed opossum COQ2 antibody; Monodelphis domestica COQ2 antibody F6RYD9 86.0%
ARP47180 Horse COQ2 antibody; Equus caballus COQ2 antibody F6RDP5 79.0%
ARP47180 Human COQ2 antibody; Homo sapiens COQ2 antibody Q96H96-3 100.0%
ARP47180 Human COQ2 antibody; Homo sapiens COQ2 antibody Q96H96 100.0%
ARP47180 Human COQ2 antibody; Homo sapiens COQ2 antibody E2QRG7 100.0%
ARP47180 Human COQ2 antibody; Homo sapiens COQ2 antibody H0YAI0 100.0%
ARP47180 Hydra COQ2 antibody; Hydra vulgaris COQ2 antibody T2M813 79.0%
ARP47180 Northern pike COQ2 antibody; Esox lucius COQ2 antibody C1BWU8 79.0%
ARP47180 Northern white-cheeked gibbon COQ2 antibody; Nomascus leucogenys COQ2 antibody G1RCR1 100.0%
ARP47180 Pig COQ2 antibody; Sus scrofa COQ2 antibody F1RVD9 86.0%
ARP47180 Rabbit COQ2 antibody; Oryctolagus cuniculus COQ2 antibody G1T0N6 93.0%
ARP47180 Rat COQ2 antibody; Rattus norvegicus COQ2 antibody Q499N4 86.0%
ARP47180 Rat COQ2 antibody; Rattus norvegicus COQ2 antibody G3V698 86.0%
ARP47180 Rhesus macaque COQ2 antibody; Macaca mulatta COQ2 antibody H9F5Z3 100.0%
ARP47180 Small-eared galago COQ2 antibody; Otolemur garnettii COQ2 antibody H0WKB3 86.0%
ARP47180 Sumatran orangutan COQ2 antibody; Pongo abelii COQ2 antibody H2PDS8 100.0%
ARP47180 Sumatran orangutan COQ2 antibody; Pongo abelii COQ2 antibody K7ET43 100.0%
ARP47180 Tasmanian devil COQ2 antibody; Sarcophilus harrisii COQ2 antibody G3VVR4 86.0%
ARP47180 Thirteen-lined ground squirrel COQ2 antibody; Spermophilus tridecemlineatus COQ2 antibody I3MAN3 93.0%
ARP47180 Western clawed frog COQ2 antibody; Xenopus tropicalis COQ2 antibody F6X1L9 79.0%
ARP47180 White-tufted-ear marmoset COQ2 antibody; Callithrix jacchus COQ2 antibody F7FLN6 93.0%
ARP47180 Yellowfever mosquito COQ2 antibody; Aedes aegypti COQ2 antibody Q16QL3 79.0%
ARP47180 Zebrafish COQ2 antibody; Danio rerio COQ2 antibody A3KNW5 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas213379_at721_B_lymphoblasts154.70036.520Details
BioGPS Gene Atlas213379_atAdipocyte30.95036.520Details
BioGPS Gene Atlas213379_atAdrenalCortex27.30036.520Details
BioGPS Gene Atlas213379_atAdrenalgland44.95036.520Details
BioGPS Gene Atlas213379_atAmygdala10.50036.520Details
BioGPS Gene Atlas213379_atAppendix12.05036.520Details
BioGPS Gene Atlas213379_atAtrioventricularNode12.45036.520Details
BioGPS Gene Atlas213379_atBDCA4+_DentriticCells66.95036.520Details
BioGPS Gene Atlas213379_atBonemarrow25.75036.520Details
BioGPS Gene Atlas213379_atBronchialEpithelialCells68.65036.520Details
BioGPS Gene Atlas213379_atCD105+_Endothelial275.60036.520Details
BioGPS Gene Atlas213379_atCD14+_Monocytes332.45036.520Details
BioGPS Gene Atlas213379_atCD19+_BCells(neg._sel.)42.45036.520Details
BioGPS Gene Atlas213379_atCD33+_Myeloid300.20036.520Details
BioGPS Gene Atlas213379_atCD34+212.45036.520Details
BioGPS Gene Atlas213379_atCD4+_Tcells14.00036.520Details
BioGPS Gene Atlas213379_atCD56+_NKCells49.35036.520Details
BioGPS Gene Atlas213379_atCD71+_EarlyErythroid79.35036.520Details
BioGPS Gene Atlas213379_atCD8+_Tcells12.00036.520Details
BioGPS Gene Atlas213379_atCardiacMyocytes28.95036.520Details
BioGPS Gene Atlas213379_atCaudatenucleus12.50036.520Details
BioGPS Gene Atlas213379_atCerebellum10.55036.520Details
BioGPS Gene Atlas213379_atCerebellumPeduncles14.90036.520Details
BioGPS Gene Atlas213379_atCiliaryGanglion10.30036.520Details
BioGPS Gene Atlas213379_atCingulateCortex9.60036.520Details
BioGPS Gene Atlas213379_atColorectaladenocarcinoma41.85036.520Details
BioGPS Gene Atlas213379_atDorsalRootGanglion13.20036.520Details
BioGPS Gene Atlas213379_atFetalThyroid20.60036.520Details
BioGPS Gene Atlas213379_atFetalbrain13.00036.520Details
BioGPS Gene Atlas213379_atFetalliver37.80036.520Details
BioGPS Gene Atlas213379_atFetallung11.65036.520Details
BioGPS Gene Atlas213379_atGlobusPallidus10.30036.520Details
BioGPS Gene Atlas213379_atHeart24.30036.520Details
BioGPS Gene Atlas213379_atHypothalamus13.15036.520Details
BioGPS Gene Atlas213379_atKidney12.15036.520Details
BioGPS Gene Atlas213379_atLeukemia_chronicMyelogenousK-56212.00036.520Details
BioGPS Gene Atlas213379_atLeukemia_promyelocytic-HL-6035.30036.520Details
BioGPS Gene Atlas213379_atLeukemialymphoblastic(MOLT-4)12.00036.520Details
BioGPS Gene Atlas213379_atLiver15.45036.520Details
BioGPS Gene Atlas213379_atLung15.05036.520Details
BioGPS Gene Atlas213379_atLymphnode15.45036.520Details
BioGPS Gene Atlas213379_atLymphoma_burkitts(Daudi)47.95036.520Details
BioGPS Gene Atlas213379_atLymphoma_burkitts(Raji)19.85036.520Details
BioGPS Gene Atlas213379_atMedullaOblongata14.85036.520Details
BioGPS Gene Atlas213379_atOccipitalLobe12.20036.520Details
BioGPS Gene Atlas213379_atOlfactoryBulb10.35036.520Details
BioGPS Gene Atlas213379_atOvary12.75036.520Details
BioGPS Gene Atlas213379_atPancreas12.10036.520Details
BioGPS Gene Atlas213379_atPancreaticIslet20.30036.520Details
BioGPS Gene Atlas213379_atParietalLobe16.50036.520Details
BioGPS Gene Atlas213379_atPituitary10.50036.520Details
BioGPS Gene Atlas213379_atPlacenta17.50036.520Details
BioGPS Gene Atlas213379_atPons25.95036.520Details
BioGPS Gene Atlas213379_atPrefrontalCortex9.35036.520Details
BioGPS Gene Atlas213379_atProstate18.20036.520Details
BioGPS Gene Atlas213379_atSalivarygland14.00036.520Details
BioGPS Gene Atlas213379_atSkeletalMuscle47.55036.520Details
BioGPS Gene Atlas213379_atSkin11.15036.520Details
BioGPS Gene Atlas213379_atSmoothMuscle17.30036.520Details
BioGPS Gene Atlas213379_atSpinalcord13.80036.520Details
BioGPS Gene Atlas213379_atSubthalamicNucleus9.35036.520Details
BioGPS Gene Atlas213379_atSuperiorCervicalGanglion43.75036.520Details
BioGPS Gene Atlas213379_atTemporalLobe18.95036.520Details
BioGPS Gene Atlas213379_atTestis12.30036.520Details
BioGPS Gene Atlas213379_atTestisGermCell10.70036.520Details
BioGPS Gene Atlas213379_atTestisIntersitial12.00036.520Details
BioGPS Gene Atlas213379_atTestisLeydigCell11.65036.520Details
BioGPS Gene Atlas213379_atTestisSeminiferousTubule19.10036.520Details
BioGPS Gene Atlas213379_atThalamus12.40036.520Details
BioGPS Gene Atlas213379_atThymus9.20036.520Details
BioGPS Gene Atlas213379_atThyroid31.30036.520Details
BioGPS Gene Atlas213379_atTongue25.35036.520Details
BioGPS Gene Atlas213379_atTonsil14.20036.520Details
BioGPS Gene Atlas213379_atTrachea11.40036.520Details
BioGPS Gene Atlas213379_atTrigeminalGanglion19.95036.520Details
BioGPS Gene Atlas213379_atUterus13.85036.520Details
BioGPS Gene Atlas213379_atUterusCorpus12.55036.520Details
BioGPS Gene Atlas213379_atWholeBlood33.90036.520Details
BioGPS Gene Atlas213379_atWholebrain16.25036.520Details
BioGPS Gene Atlas213379_atcolon86.85036.520Details
BioGPS Gene Atlas213379_atpineal_day40.42036.520Details
BioGPS Gene Atlas213379_atpineal_night30.10036.520Details
BioGPS Gene Atlas213379_atretina18.22536.520Details
BioGPS Gene Atlas213379_atsmall_intestine61.95036.520Details
BioGPS NCI60213379_at786911.094466.400Details
BioGPS NCI60213379_atA172233.019466.400Details
BioGPS NCI60213379_atA204950.481466.400Details
BioGPS NCI60213379_atA361130.954466.400Details
BioGPS NCI60213379_atA498305.737466.400Details
BioGPS NCI60213379_atA549536.197466.400Details
BioGPS NCI60213379_atACC3363.289466.400Details
BioGPS NCI60213379_atACHN248.497466.400Details
BioGPS NCI60213379_atALVA311209.823466.400Details
BioGPS NCI60213379_atCAKI1547.111466.400Details
BioGPS NCI60213379_atCCRT CEM122.850466.400Details
BioGPS NCI60213379_atCOLO205613.553466.400Details
BioGPS NCI60213379_atDLD1320.020466.400Details
BioGPS NCI60213379_atDU145497.400466.400Details
BioGPS NCI60213379_atEKVX1037.115466.400Details
BioGPS NCI60213379_atGM133499.759466.400Details
BioGPS NCI60213379_atGM1600422.508466.400Details
BioGPS NCI60213379_atGM2313702.980466.400Details
BioGPS NCI60213379_atGM2345239.646466.400Details
BioGPS NCI60213379_atGM2493333.080466.400Details
BioGPS NCI60213379_atGM97457.980466.400Details
BioGPS NCI60213379_atHCC2998247.258466.400Details
BioGPS NCI60213379_atHCT1161046.169466.400Details
BioGPS NCI60213379_atHCT15216.892466.400Details
BioGPS NCI60213379_atHEK 293 T-rex362.119466.400Details
BioGPS NCI60213379_atHEK 293T497.089466.400Details
BioGPS NCI60213379_atHEK293590.461466.400Details
BioGPS NCI60213379_atHELA548.053466.400Details
BioGPS NCI60213379_atHEPG2247.510466.400Details
BioGPS NCI60213379_atHL60179.728466.400Details
BioGPS NCI60213379_atHOP62180.159466.400Details
BioGPS NCI60213379_atHOP92415.139466.400Details
BioGPS NCI60213379_atHS578T309.625466.400Details
BioGPS NCI60213379_atHSG400.777466.400Details
BioGPS NCI60213379_atHT1080124.775466.400Details
BioGPS NCI60213379_atHT29842.513466.400Details
BioGPS NCI60213379_atIGROV1355.580466.400Details
BioGPS NCI60213379_atIOSE80375.907466.400Details
BioGPS NCI60213379_atJURKAT203.343466.400Details
BioGPS NCI60213379_atK562165.179466.400Details
BioGPS NCI60213379_atKM12797.170466.400Details
BioGPS NCI60213379_atLN18613.511466.400Details
BioGPS NCI60213379_atLNCAP178.007466.400Details
BioGPS NCI60213379_atLOX IMVI167.615466.400Details
BioGPS NCI60213379_atM14290.168466.400Details
BioGPS NCI60213379_atMALME 3M159.674466.400Details
BioGPS NCI60213379_atMCF7519.440466.400Details
BioGPS NCI60213379_atMD MB231776.293466.400Details
BioGPS NCI60213379_atMDA MB435401.830466.400Details
BioGPS NCI60213379_atMOLT4132.439466.400Details
BioGPS NCI60213379_atNCI 460517.290466.400Details
BioGPS NCI60213379_atNCI H226347.695466.400Details
BioGPS NCI60213379_atNCI H23658.895466.400Details
BioGPS NCI60213379_atNCI H322M444.265466.400Details
BioGPS NCI60213379_atNCVADR RES1108.247466.400Details
BioGPS NCI60213379_atOVCAR3441.979466.400Details
BioGPS NCI60213379_atOVCAR4269.467466.400Details
BioGPS NCI60213379_atOVCAR51088.871466.400Details
BioGPS NCI60213379_atOVCAR8845.695466.400Details
BioGPS NCI60213379_atPANC1305.342466.400Details
BioGPS NCI60213379_atRL7160.343466.400Details
BioGPS NCI60213379_atRPMI 8226132.735466.400Details
BioGPS NCI60213379_atRS11846285.642466.400Details
BioGPS NCI60213379_atRXF393294.344466.400Details
BioGPS NCI60213379_atSAOS2339.452466.400Details
BioGPS NCI60213379_atSF268365.562466.400Details
BioGPS NCI60213379_atSF295909.751466.400Details
BioGPS NCI60213379_atSF539205.673466.400Details
BioGPS NCI60213379_atSHSYSY+RA57.971466.400Details
BioGPS NCI60213379_atSHSYSY-RA54.046466.400Details
BioGPS NCI60213379_atSKMEL2421.236466.400Details
BioGPS NCI60213379_atSKMEL28109.830466.400Details
BioGPS NCI60213379_atSKMEL565.070466.400Details
BioGPS NCI60213379_atSKOV31507.367466.400Details
BioGPS NCI60213379_atSN12C580.709466.400Details
BioGPS NCI60213379_atSNB19545.318466.400Details
BioGPS NCI60213379_atSNB75205.017466.400Details
BioGPS NCI60213379_atSR147.516466.400Details
BioGPS NCI60213379_atSW620382.545466.400Details
BioGPS NCI60213379_atT24661.643466.400Details
BioGPS NCI60213379_atT3M4121.606466.400Details
BioGPS NCI60213379_atTK10261.780466.400Details
BioGPS NCI60213379_atU118875.990466.400Details
BioGPS NCI60213379_atU138628.529466.400Details
BioGPS NCI60213379_atU20S215.100466.400Details
BioGPS NCI60213379_atU251616.279466.400Details
BioGPS NCI60213379_atU871915.994466.400Details
BioGPS NCI60213379_atUACC257153.554466.400Details
BioGPS NCI60213379_atUACC6274.204466.400Details
BioGPS NCI60213379_atUO31682.138466.400Details
BioGPS NCI60213379_atZR75_1274.753466.400Details
BioGPS NCI60213379_atastrocytes112.419466.400Details
BioGPS NCI60213379_athuh-7337.714466.400Details