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Gene ID: 1259 | CNGA1 Antibody Resource


CNGA1 Antibody Resource
Gene Full Name: 
cyclic nucleotide gated channel alpha 1
Uniprot: 
P29973
Protein Name: 
cGMP-gated cation channel alpha-1
Nucleotide: 
NM_000087
Alias: 
CNCG;CNG1;RP49;CNCG1;CNG-1;RCNC1;RCNCa;RCNCalpha;
Ensembl: 
ENSG00000198515
Location: 
4p12
HPRD: 
00445
NCBI Gene: 
1259
MIM: 
123825

Summary: 
The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Function: 
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors.
Subcellular location: 
Membrane; Multi-pass membrane protein.
PTM: 
Glycoprotein;
Disease: 
Retinitis pigmentosa 49 (RP49) [MIM:613756]: A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP34918_P050 CNGA1 Antibody (ARP34918_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details
Polyclonal Antibody OAAF03481 CNGA1 Antibody (OAAF03481) Polyclonal Human, Mouse, Rat WB, ELISA 100 ug $229 Details

Show all CNGA1 antibodies


Product Images
CNGA1 Antibody (OAAF03481) in HepG2, K562 cells using Western Blot

Sample Type: HepG2, K562


CNGA1 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP34918 Hipposideros larvatus CNGA1 antibody G9BLQ9 93.0%
ARP34918 Rhinolophus pearsonii CNGA1 antibody G9BLR0 93.0%
ARP34918 Nyctalus plancyi CNGA1 antibody G9BLS4 93.0%
ARP34918 Nyctalus plancyi CNGA1 antibody G9BLQ3 93.0%
ARP34918 Chaerephon plicatus CNGA1 antibody G9BLQ4 93.0%
ARP34918 Nyctalus plancyi CNGA1 antibody G9BLQ5 93.0%
ARP34918 African elephant CNGA1 antibody; Loxodonta africana CNGA1 antibody G3TCG9 93.0%
ARP34918 African elephant CNGA1 antibody; Loxodonta africana CNGA1 antibody G3U4X0 93.0%
ARP34918 Black-bearded tomb bat CNGA1 antibody; Taphozous melanopogon CNGA1 antibody G9BLR7 93.0%
ARP34918 Bovine CNGA1 antibody; Bos taurus CNGA1 antibody Q00194 86.0%
ARP34918 Cat CNGA1 antibody; Felis catus CNGA1 antibody M3WAV3 93.0%
ARP34918 Chimpanzee CNGA1 antibody; Pan troglodytes CNGA1 antibody H2QPF2 100.0%
ARP34918 Chinese softshell turtle CNGA1 antibody; Pelodiscus sinensis CNGA1 antibody K7FWR1 86.0%
ARP34918 Chinese water myotis CNGA1 antibody; Myotis laniger CNGA1 antibody G9BLQ8 93.0%
ARP34918 Chinese water myotis CNGA1 antibody; Myotis laniger CNGA1 antibody G9BLQ6 93.0%
ARP34918 Collared flycatcher CNGA1 antibody; Ficedula albicollis CNGA1 antibody U3JK97 82.0%
ARP34918 David's myotis CNGA1 antibody; Myotis davidii CNGA1 antibody G9BLS6 93.0%
ARP34918 Dog CNGA1 antibody; Canis familiaris CNGA1 antibody Q28279 93.0%
ARP34918 Dog CNGA1 antibody; Canis familiaris CNGA1 antibody F1Q3U8 93.0%
ARP34918 Duckbill platypus CNGA1 antibody; Ornithorhynchus anatinus CNGA1 antibody F6SPJ8 86.0%
ARP34918 European domestic ferret CNGA1 antibody; Mustela putorius furo CNGA1 antibody M3Y1L9 93.0%
ARP53904 European domestic ferret CNGA1 antibody; Mustela putorius furo CNGA1 antibody M3Y1L9 79.0%
ARP34918 Giant panda CNGA1 antibody; Ailuropoda melanoleuca CNGA1 antibody D2H5N6 93.0%
ARP34918 Gray short-tailed opossum CNGA1 antibody; Monodelphis domestica CNGA1 antibody F7EUQ9 93.0%
ARP34918 great roundleaf bat CNGA1 antibody; Hipposideros armiger CNGA1 antibody G9BLR3 93.0%
ARP34918 great roundleaf bat CNGA1 antibody; Hipposideros armiger CNGA1 antibody G9BLR6 93.0%
ARP34918 Greater bamboo bat CNGA1 antibody; Tylonycteris robustula CNGA1 antibody G9BLS2 93.0%
ARP34918 Horse CNGA1 antibody; Equus caballus CNGA1 antibody F6TI96 93.0%
ARP34918 Human CNGA1 antibody; Homo sapiens CNGA1 antibody P29973-2 100.0%
ARP34918 Human CNGA1 antibody; Homo sapiens CNGA1 antibody P29973 100.0%
ARP34918 Indian short-nosed fruit bat CNGA1 antibody; Cynopterus sphinx CNGA1 antibody G9BLQ2 93.0%
ARP34918 Japanese long-fingered bat CNGA1 antibody; Miniopterus fuliginosus CNGA1 antibody G9BLR1 93.0%
ARP34918 Japanese long-fingered bat CNGA1 antibody; Miniopterus fuliginosus CNGA1 antibody G9BLQ1 93.0%
ARP34918 Least horseshoe bat CNGA1 antibody; Rhinolophus pusillus CNGA1 antibody G9BLR5 93.0%
ARP34918 Least horseshoe bat CNGA1 antibody; Rhinolophus pusillus CNGA1 antibody G9BLS8 93.0%
ARP34918 Leschenault's rousette CNGA1 antibody; Rousettus leschenaultii CNGA1 antibody G9BLR4 93.0%
ARP34918 Leschenault's rousette CNGA1 antibody; Rousettus leschenaultii CNGA1 antibody G9BLS9 93.0%
ARP34918 Lesser bamboo bat CNGA1 antibody; Tylonycteris pachypus CNGA1 antibody G9BLS3 93.0%
ARP34918 Lesser dawn bat CNGA1 antibody; Eonycteris spelaea CNGA1 antibody G9BLS5 93.0%
ARP34918 Marshall's horseshoe bat CNGA1 antibody; Rhinolophus marshalli CNGA1 antibody G9BLT0 93.0%
ARP34918 Mouse CNGA1 antibody; Mus musculus CNGA1 antibody P29974 93.0%
ARP34918 Northern white-cheeked gibbon CNGA1 antibody; Nomascus leucogenys CNGA1 antibody G1S6E7 100.0%
ARP34918 Pig CNGA1 antibody; Sus scrofa CNGA1 antibody F1S3S4 86.0%
ARP34918 Pomona leaf-nosed bat CNGA1 antibody; Hipposideros pomona CNGA1 antibody G9BLR2 100.0%
ARP34918 Pomona leaf-nosed bat CNGA1 antibody; Hipposideros pomona CNGA1 antibody G9BLS7 100.0%
ARP34918 Rat CNGA1 antibody; Rattus norvegicus CNGA1 antibody Q62927 93.0%
ARP34918 Rat CNGA1 antibody; Rattus norvegicus CNGA1 antibody F1LQN0 93.0%
ARP34918 Rickett's big-footed bat CNGA1 antibody; Myotis ricketti CNGA1 antibody G9BLQ7 93.0%
ARP34918 Small-eared galago CNGA1 antibody; Otolemur garnettii CNGA1 antibody H0XSM4 93.0%
ARP36374 Striped bass CNGA1 antibody; Morone saxatilis CNGA1 antibody Q3I0N0 83.0%
ARP34918 Sumatran orangutan CNGA1 antibody; Pongo abelii CNGA1 antibody H2PD87 100.0%
ARP34918 Tasmanian devil CNGA1 antibody; Sarcophilus harrisii CNGA1 antibody G3VDU3 100.0%
ARP34918 Thirteen-lined ground squirrel CNGA1 antibody; Spermophilus tridecemlineatus CNGA1 antibody I3LYA9 93.0%
ARP35050 Thirteen-lined ground squirrel CNGA1 antibody; Spermophilus tridecemlineatus CNGA1 antibody I3LYA9 85.0%
ARP34918 Western clawed frog CNGA1 antibody; Xenopus tropicalis CNGA1 antibody L7N492 90.0%
ARP34918 White-tufted-ear marmoset CNGA1 antibody; Callithrix jacchus CNGA1 antibody F7I8Y1 100.0%
ARP34918 White-tufted-ear marmoset CNGA1 antibody; Callithrix jacchus CNGA1 antibody F7I8Y4 100.0%
ARP34918 Zebra finch CNGA1 antibody; Taeniopygia guttata CNGA1 antibody H0ZCV5 82.0%
ARP34918 Zebrafish CNGA1 antibody; Danio rerio CNGA1 antibody E7FE78 91.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas206417_at721_B_lymphoblasts6.0005.610Details
BioGPS Gene Atlas206417_atAdipocyte5.2005.610Details
BioGPS Gene Atlas206417_atAdrenalCortex5.9005.610Details
BioGPS Gene Atlas206417_atAdrenalgland4.5005.610Details
BioGPS Gene Atlas206417_atAmygdala5.3505.610Details
BioGPS Gene Atlas206417_atAppendix7.3505.610Details
BioGPS Gene Atlas206417_atAtrioventricularNode5.8505.610Details
BioGPS Gene Atlas206417_atBDCA4+_DentriticCells5.3505.610Details
BioGPS Gene Atlas206417_atBonemarrow5.3005.610Details
BioGPS Gene Atlas206417_atBronchialEpithelialCells5.1005.610Details
BioGPS Gene Atlas206417_atCD105+_Endothelial4.9505.610Details
BioGPS Gene Atlas206417_atCD14+_Monocytes5.4505.610Details
BioGPS Gene Atlas206417_atCD19+_BCells(neg._sel.)5.3505.610Details
BioGPS Gene Atlas206417_atCD33+_Myeloid6.2505.610Details
BioGPS Gene Atlas206417_atCD34+6.1005.610Details
BioGPS Gene Atlas206417_atCD4+_Tcells5.3005.610Details
BioGPS Gene Atlas206417_atCD56+_NKCells5.8505.610Details
BioGPS Gene Atlas206417_atCD71+_EarlyErythroid4.8505.610Details
BioGPS Gene Atlas206417_atCD8+_Tcells4.8005.610Details
BioGPS Gene Atlas206417_atCardiacMyocytes6.9505.610Details
BioGPS Gene Atlas206417_atCaudatenucleus4.7005.610Details
BioGPS Gene Atlas206417_atCerebellum4.3005.610Details
BioGPS Gene Atlas206417_atCerebellumPeduncles6.0505.610Details
BioGPS Gene Atlas206417_atCiliaryGanglion3.9005.610Details
BioGPS Gene Atlas206417_atCingulateCortex5.4505.610Details
BioGPS Gene Atlas206417_atColorectaladenocarcinoma5.1505.610Details
BioGPS Gene Atlas206417_atDorsalRootGanglion4.4005.610Details
BioGPS Gene Atlas206417_atFetalThyroid5.1005.610Details
BioGPS Gene Atlas206417_atFetalbrain5.1505.610Details
BioGPS Gene Atlas206417_atFetalliver7.7005.610Details
BioGPS Gene Atlas206417_atFetallung4.3005.610Details
BioGPS Gene Atlas206417_atGlobusPallidus3.9505.610Details
BioGPS Gene Atlas206417_atHeart7.3505.610Details
BioGPS Gene Atlas206417_atHypothalamus5.6505.610Details
BioGPS Gene Atlas206417_atKidney5.1005.610Details
BioGPS Gene Atlas206417_atLeukemia_chronicMyelogenousK-5624.8005.610Details
BioGPS Gene Atlas206417_atLeukemia_promyelocytic-HL-604.5505.610Details
BioGPS Gene Atlas206417_atLeukemialymphoblastic(MOLT-4)4.0505.610Details
BioGPS Gene Atlas206417_atLiver7.6005.610Details
BioGPS Gene Atlas206417_atLung5.7005.610Details
BioGPS Gene Atlas206417_atLymphnode4.5005.610Details
BioGPS Gene Atlas206417_atLymphoma_burkitts(Daudi)6.7505.610Details
BioGPS Gene Atlas206417_atLymphoma_burkitts(Raji)7.5005.610Details
BioGPS Gene Atlas206417_atMedullaOblongata5.2505.610Details
BioGPS Gene Atlas206417_atOccipitalLobe4.6505.610Details
BioGPS Gene Atlas206417_atOlfactoryBulb7.0005.610Details
BioGPS Gene Atlas206417_atOvary3.7005.610Details
BioGPS Gene Atlas206417_atPancreas4.4505.610Details
BioGPS Gene Atlas206417_atPancreaticIslet5.7005.610Details
BioGPS Gene Atlas206417_atParietalLobe5.9005.610Details
BioGPS Gene Atlas206417_atPituitary6.1505.610Details
BioGPS Gene Atlas206417_atPlacenta5.2005.610Details
BioGPS Gene Atlas206417_atPons5.0505.610Details
BioGPS Gene Atlas206417_atPrefrontalCortex6.4005.610Details
BioGPS Gene Atlas206417_atProstate6.0005.610Details
BioGPS Gene Atlas206417_atSalivarygland4.2505.610Details
BioGPS Gene Atlas206417_atSkeletalMuscle7.9005.610Details
BioGPS Gene Atlas206417_atSkin7.0505.610Details
BioGPS Gene Atlas206417_atSmoothMuscle5.9005.610Details
BioGPS Gene Atlas206417_atSpinalcord5.6505.610Details
BioGPS Gene Atlas206417_atSubthalamicNucleus5.0505.610Details
BioGPS Gene Atlas206417_atSuperiorCervicalGanglion8.4505.610Details
BioGPS Gene Atlas206417_atTemporalLobe6.0505.610Details
BioGPS Gene Atlas206417_atTestis4.5505.610Details
BioGPS Gene Atlas206417_atTestisGermCell4.3505.610Details
BioGPS Gene Atlas206417_atTestisIntersitial4.4005.610Details
BioGPS Gene Atlas206417_atTestisLeydigCell5.6505.610Details
BioGPS Gene Atlas206417_atTestisSeminiferousTubule4.7505.610Details
BioGPS Gene Atlas206417_atThalamus5.3505.610Details
BioGPS Gene Atlas206417_atThymus4.0505.610Details
BioGPS Gene Atlas206417_atThyroid6.4005.610Details
BioGPS Gene Atlas206417_atTongue5.5505.610Details
BioGPS Gene Atlas206417_atTonsil5.1005.610Details
BioGPS Gene Atlas206417_atTrachea4.3505.610Details
BioGPS Gene Atlas206417_atTrigeminalGanglion5.8005.610Details
BioGPS Gene Atlas206417_atUterus4.3005.610Details
BioGPS Gene Atlas206417_atUterusCorpus11.6505.610Details
BioGPS Gene Atlas206417_atWholeBlood5.6005.610Details
BioGPS Gene Atlas206417_atWholebrain4.3505.610Details
BioGPS Gene Atlas206417_atcolon5.2005.610Details
BioGPS Gene Atlas206417_atpineal_day6.3205.610Details
BioGPS Gene Atlas206417_atpineal_night6.1005.610Details
BioGPS Gene Atlas206417_atretina7.4755.610Details
BioGPS Gene Atlas206417_atsmall_intestine4.9005.610Details
BioGPS NCI60206417_at7865.3985.250Details
BioGPS NCI60206417_atA1724.9735.250Details
BioGPS NCI60206417_atA2045.1885.250Details
BioGPS NCI60206417_atA3615.2945.250Details
BioGPS NCI60206417_atA4985.2175.250Details
BioGPS NCI60206417_atA5495.3535.250Details
BioGPS NCI60206417_atACC35.6575.250Details
BioGPS NCI60206417_atACHN4.9265.250Details
BioGPS NCI60206417_atALVA315.8075.250Details
BioGPS NCI60206417_atCAKI15.4775.250Details
BioGPS NCI60206417_atCCRT CEM5.9715.250Details
BioGPS NCI60206417_atCOLO2055.3035.250Details
BioGPS NCI60206417_atDLD15.1435.250Details
BioGPS NCI60206417_atDU1455.0185.250Details
BioGPS NCI60206417_atEKVX4.9115.250Details
BioGPS NCI60206417_atGM1335.3675.250Details
BioGPS NCI60206417_atGM16005.4995.250Details
BioGPS NCI60206417_atGM23135.3335.250Details
BioGPS NCI60206417_atGM23455.2495.250Details
BioGPS NCI60206417_atGM24935.5555.250Details
BioGPS NCI60206417_atGM975.9235.250Details
BioGPS NCI60206417_atHCC29984.7435.250Details
BioGPS NCI60206417_atHCT1165.2675.250Details
BioGPS NCI60206417_atHCT154.8645.250Details
BioGPS NCI60206417_atHEK 293 T-rex5.3855.250Details
BioGPS NCI60206417_atHEK 293T5.1805.250Details
BioGPS NCI60206417_atHEK2935.2185.250Details
BioGPS NCI60206417_atHELA4.8035.250Details
BioGPS NCI60206417_atHEPG25.2245.250Details
BioGPS NCI60206417_atHL605.6145.250Details
BioGPS NCI60206417_atHOP625.1845.250Details
BioGPS NCI60206417_atHOP925.0605.250Details
BioGPS NCI60206417_atHS578T5.1365.250Details
BioGPS NCI60206417_atHSG5.1345.250Details
BioGPS NCI60206417_atHT10805.1125.250Details
BioGPS NCI60206417_atHT295.6705.250Details
BioGPS NCI60206417_atIGROV15.1925.250Details
BioGPS NCI60206417_atIOSE805.1795.250Details
BioGPS NCI60206417_atJURKAT5.2225.250Details
BioGPS NCI60206417_atK5625.6505.250Details
BioGPS NCI60206417_atKM125.6055.250Details
BioGPS NCI60206417_atLN184.7955.250Details
BioGPS NCI60206417_atLNCAP5.2375.250Details
BioGPS NCI60206417_atLOX IMVI5.2375.250Details
BioGPS NCI60206417_atM145.1795.250Details
BioGPS NCI60206417_atMALME 3M5.6115.250Details
BioGPS NCI60206417_atMCF75.0105.250Details
BioGPS NCI60206417_atMD MB2315.3465.250Details
BioGPS NCI60206417_atMDA MB4355.6605.250Details
BioGPS NCI60206417_atMOLT45.4545.250Details
BioGPS NCI60206417_atNCI 4605.3875.250Details
BioGPS NCI60206417_atNCI H2265.3805.250Details
BioGPS NCI60206417_atNCI H235.2265.250Details
BioGPS NCI60206417_atNCI H322M5.2195.250Details
BioGPS NCI60206417_atNCVADR RES4.9375.250Details
BioGPS NCI60206417_atOVCAR35.5295.250Details
BioGPS NCI60206417_atOVCAR45.2205.250Details
BioGPS NCI60206417_atOVCAR55.1185.250Details
BioGPS NCI60206417_atOVCAR84.8155.250Details
BioGPS NCI60206417_atPANC15.3275.250Details
BioGPS NCI60206417_atRL75.3345.250Details
BioGPS NCI60206417_atRPMI 82265.3185.250Details
BioGPS NCI60206417_atRS118465.5535.250Details
BioGPS NCI60206417_atRXF3935.2015.250Details
BioGPS NCI60206417_atSAOS25.2805.250Details
BioGPS NCI60206417_atSF2685.1745.250Details
BioGPS NCI60206417_atSF2955.1455.250Details
BioGPS NCI60206417_atSF5394.9295.250Details
BioGPS NCI60206417_atSHSYSY+RA5.0905.250Details
BioGPS NCI60206417_atSHSYSY-RA5.1345.250Details
BioGPS NCI60206417_atSKMEL25.2225.250Details
BioGPS NCI60206417_atSKMEL285.2545.250Details
BioGPS NCI60206417_atSKMEL55.0785.250Details
BioGPS NCI60206417_atSKOV35.4675.250Details
BioGPS NCI60206417_atSN12C5.1735.250Details
BioGPS NCI60206417_atSNB195.0525.250Details
BioGPS NCI60206417_atSNB755.1555.250Details
BioGPS NCI60206417_atSR5.3765.250Details
BioGPS NCI60206417_atSW6205.3035.250Details
BioGPS NCI60206417_atT245.3085.250Details
BioGPS NCI60206417_atT3M45.4835.250Details
BioGPS NCI60206417_atTK105.1835.250Details
BioGPS NCI60206417_atU1185.0525.250Details
BioGPS NCI60206417_atU1384.8225.250Details
BioGPS NCI60206417_atU20S5.1325.250Details
BioGPS NCI60206417_atU2515.1295.250Details
BioGPS NCI60206417_atU875.0175.250Details
BioGPS NCI60206417_atUACC2575.0555.250Details
BioGPS NCI60206417_atUACC625.3235.250Details
BioGPS NCI60206417_atUO315.0035.250Details
BioGPS NCI60206417_atZR75_15.4315.250Details
BioGPS NCI60206417_atastrocytes5.3265.250Details
BioGPS NCI60206417_athuh-75.6065.250Details