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Gene ID: 134147 | CMBL Antibody Resource


CMBL Antibody Resource
Gene Full Name: 
carboxymethylenebutenolidase homolog (Pseudomonas)
Uniprot: 
Q96DG6
Protein Name: 
carboxymethylenebutenolidase homolog
Nucleotide: 
NM_138809
Alias: 
JS-1;
Ensembl: 
Location: 
5p15.2
HPRD: 
14055
NCBI Gene: 
134147
MIM: 
613379

Summary: 
CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010]
Function: 
Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin.
Subcellular location: 
Cytoplasm › cytosol .
PTM: 
Acetylation;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB03291 CMBL antibody - C-terminal region (OAAB03291) Human; Mouse WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP52654_P050 CMBL Antibody (ARP52654_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP52655_P050 CMBL Antibody (ARP52655_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details

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Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP52655 African clawed frog CMBL antibody; Xenopus laevis CMBL antibody Q5XH09 91.0%
ARP52654 African clawed frog CMBL antibody; Xenopus laevis CMBL antibody Q5XH09 86.0%
ARP52654 Bovine CMBL antibody; Bos taurus CMBL antibody Q3T141 100.0%
ARP52654 Bovine CMBL antibody; Bos taurus CMBL antibody F1N2I5 100.0%
ARP52655 Bovine CMBL antibody; Bos taurus CMBL antibody F1N2I5 100.0%
ARP52655 Cat CMBL antibody; Felis catus CMBL antibody M3X3U3 100.0%
ARP52654 Cat CMBL antibody; Felis catus CMBL antibody M3X3U3 86.0%
ARP52655 Channel catfish CMBL antibody; Ictalurus punctatus CMBL antibody E3TF52 79.0%
ARP52654 Chimpanzee CMBL antibody; Pan troglodytes CMBL antibody K7CFW7 100.0%
ARP52655 Chimpanzee CMBL antibody; Pan troglodytes CMBL antibody K7CFW7 100.0%
ARP52654 Chimpanzee CMBL antibody; Pan troglodytes CMBL antibody H2QQM8 100.0%
ARP52655 Chimpanzee CMBL antibody; Pan troglodytes CMBL antibody H2QQM8 100.0%
ARP52655 Dog CMBL antibody; Canis familiaris CMBL antibody E2RF91 100.0%
ARP52654 Dog CMBL antibody; Canis familiaris CMBL antibody E2RF91 93.0%
ARP52655 Duckbill platypus CMBL antibody; Ornithorhynchus anatinus CMBL antibody F6Z9U4 93.0%
ARP52654 Duckbill platypus CMBL antibody; Ornithorhynchus anatinus CMBL antibody F6Z9U4 79.0%
ARP52654 European domestic ferret CMBL antibody; Mustela putorius furo CMBL antibody M3YII9 100.0%
ARP52655 European domestic ferret CMBL antibody; Mustela putorius furo CMBL antibody M3YII9 100.0%
ARP52655 European seabass CMBL antibody; Dicentrarchus labrax CMBL antibody E6ZIK3 93.0%
ARP52654 Giant panda CMBL antibody; Ailuropoda melanoleuca CMBL antibody D2H9W7 100.0%
ARP52655 Giant panda CMBL antibody; Ailuropoda melanoleuca CMBL antibody D2H9W7 100.0%
ARP52655 Gray short-tailed opossum CMBL antibody; Monodelphis domestica CMBL antibody F7GD97 86.0%
ARP52654 Horse CMBL antibody; Equus caballus CMBL antibody F6UL42 100.0%
ARP52655 Horse CMBL antibody; Equus caballus CMBL antibody F6UL42 100.0%
ARP52654 Human CMBL antibody; Homo sapiens CMBL antibody Q96DG6 100.0%
ARP52655 Human CMBL antibody; Homo sapiens CMBL antibody Q96DG6 100.0%
ARP52654 Mouse CMBL antibody; Mus musculus CMBL antibody E0CXH4 100.0%
ARP52654 Mouse CMBL antibody; Mus musculus CMBL antibody E0CXT6 100.0%
ARP52654 Mouse CMBL antibody; Mus musculus CMBL antibody Q8R1G2 100.0%
ARP52655 Mouse CMBL antibody; Mus musculus CMBL antibody Q8R1G2 100.0%
ARP52655 Northern pike CMBL antibody; Esox lucius CMBL antibody C1BWH0 86.0%
ARP52655 Pig CMBL antibody; Sus scrofa CMBL antibody I3L8S3 100.0%
ARP52655 Rabbit CMBL antibody; Oryctolagus cuniculus CMBL antibody G1SQA1 100.0%
ARP52654 Rabbit CMBL antibody; Oryctolagus cuniculus CMBL antibody G1SQA1 93.0%
ARP52654 Rat CMBL antibody; Rattus norvegicus CMBL antibody Q7TP52 100.0%
ARP52655 Rat CMBL antibody; Rattus norvegicus CMBL antibody Q7TP52 100.0%
ARP52654 Rhesus macaque CMBL antibody; Macaca mulatta CMBL antibody F7GKB9 100.0%
ARP52655 Rhesus macaque CMBL antibody; Macaca mulatta CMBL antibody F7GKB9 100.0%
ARP52654 Small-eared galago CMBL antibody; Otolemur garnettii CMBL antibody H0XGD9 100.0%
ARP52655 Small-eared galago CMBL antibody; Otolemur garnettii CMBL antibody H0XGD9 100.0%
ARP52655 Spotted green pufferfish CMBL antibody; Tetraodon nigroviridis CMBL antibody Q4SMY3 79.0%
ARP52654 Sumatran orangutan CMBL antibody; Pongo abelii CMBL antibody Q5RBU3 100.0%
ARP52655 Sumatran orangutan CMBL antibody; Pongo abelii CMBL antibody Q5RBU3 100.0%
ARP52654 Tasmanian devil CMBL antibody; Sarcophilus harrisii CMBL antibody G3VEG2 79.0%
ARP52654 Thirteen-lined ground squirrel CMBL antibody; Spermophilus tridecemlineatus CMBL antibody I3MZW6 100.0%
ARP52655 Thirteen-lined ground squirrel CMBL antibody; Spermophilus tridecemlineatus CMBL antibody I3MZW6 93.0%
ARP52655 Western clawed frog CMBL antibody; Xenopus tropicalis CMBL antibody Q6P7K0 91.0%
ARP52654 Western clawed frog CMBL antibody; Xenopus tropicalis CMBL antibody Q6P7K0 86.0%
ARP52654 White-tufted-ear marmoset CMBL antibody; Callithrix jacchus CMBL antibody U3DFD0 100.0%
ARP52655 White-tufted-ear marmoset CMBL antibody; Callithrix jacchus CMBL antibody U3DFD0 100.0%
ARP52655 Zebrafish CMBL antibody; Danio rerio CMBL antibody A7MBU9 100.0%

Tissue & Cell Line Gene Expression Data