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Gene ID: 1215 | CMA1 Antibody Resource


CMA1 Antibody Resource
Gene Full Name: 
chymase 1, mast cell
Uniprot: 
P23946
Protein Name: 
chymase
Nucleotide: 
NM_001836
Alias: 
CYH;MCT1;chymase;
Ensembl: 
ENSG00000092009
Location: 
14q11.2
HPRD: 
00346
NCBI Gene: 
1215
MIM: 
118938

Summary: 
This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases. [provided by RefSeq, Jul 2008]
Function: 
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
Subcellular location: 
Secreted. Cytoplasmic granule. Note: Mast cell granules.
PTM: 
Disulfide bond;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Monoclonal Antibody OASA03098 CMA1 Antibody (OASA03098) Human ELISA, IHC-FFPE, WB 0.1mg $530 Details
Monoclonal Antibody OASA03099 CMA1 Antibody (OASA03099) Human IHC-FFPE 10ug $170 Details
Polyclonal Antibody ARP59991_P050 CMA1 antibody - C-terminal region (ARP59991_P050) Polyclonal Bovine, Dog, Guinea pig, Human WB 50ug $289 Details
Polyclonal Antibody OAAB04730 CMA1 antibody - C-terminal region (OAAB04730) Human WB, ELISA 400ul $289 Details
Polyclonal Antibody OAAB04731 CMA1 antibody - center region (OAAB04731) Human WB, ELISA 400ul $289 Details

Show all CMA1 antibodies


Product Images
CMA1 antibody - C-terminal region (ARP59991_P050) in Human COLO205 cells using Western Blot

Sample Type: Human COLO205


CMA1 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP59991 Cat CMA1 antibody; Felis catus CMA1 antibody M3W4D6 93.0%
ARP59991 Chimpanzee CMA1 antibody; Pan troglodytes CMA1 antibody H2Q838 100.0%
ARP59991 Crab-eating macaque CMA1 antibody; Macaca fascicularis CMA1 antibody P56435 100.0%
ARP59991 Dog CMA1 antibody; Canis familiaris CMA1 antibody P21842 100.0%
ARP59991 European domestic ferret CMA1 antibody; Mustela putorius furo CMA1 antibody M3Y2J4 86.0%
ARP59991 Giant panda CMA1 antibody; Ailuropoda melanoleuca CMA1 antibody G1MBQ5 86.0%
ARP59991 Gray short-tailed opossum CMA1 antibody; Monodelphis domestica CMA1 antibody F6PMW7 79.0%
ARP59991 Gray short-tailed opossum CMA1 antibody; Monodelphis domestica CMA1 antibody F6PN48 79.0%
ARP59991 Guinea pig CMA1 antibody; Cavia porcellus CMA1 antibody A7WPL7 86.0%
ARP59991 Guinea pig CMA1 antibody; Cavia porcellus CMA1 antibody H0VLD0 86.0%
ARP59991 Hamadryas baboon CMA1 antibody; Papio hamadryas CMA1 antibody P52195 100.0%
ARP59991 Human CMA1 antibody; Homo sapiens CMA1 antibody P23946 100.0%
ARP59991 Human CMA1 antibody; Homo sapiens CMA1 antibody Q3SY37 100.0%
ARP59991 Rhesus macaque CMA1 antibody; Macaca mulatta CMA1 antibody F6SA35 100.0%
ARP59991 Rhesus macaque CMA1 antibody; Macaca mulatta CMA1 antibody F6SAJ2 100.0%
ARP59991 Rhesus macaque CMA1 antibody; Macaca mulatta CMA1 antibody F6XM02 100.0%
ARP59991 Sumatran orangutan CMA1 antibody; Pongo abelii CMA1 antibody H2NKX6 100.0%
ARP59991 White-tufted-ear marmoset CMA1 antibody; Callithrix jacchus CMA1 antibody F7GM64 93.0%
ARP59991 White-tufted-ear marmoset CMA1 antibody; Callithrix jacchus CMA1 antibody F7GM81 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas214533_at721_B_lymphoblasts6.1505.140Details
BioGPS Gene Atlas214533_atAdipocyte4.9005.140Details
BioGPS Gene Atlas214533_atAdrenalCortex6.7005.140Details
BioGPS Gene Atlas214533_atAdrenalgland4.4505.140Details
BioGPS Gene Atlas214533_atAmygdala5.1005.140Details
BioGPS Gene Atlas214533_atAppendix5.2505.140Details
BioGPS Gene Atlas214533_atAtrioventricularNode4.3505.140Details
BioGPS Gene Atlas214533_atBDCA4+_DentriticCells5.2005.140Details
BioGPS Gene Atlas214533_atBonemarrow5.5005.140Details
BioGPS Gene Atlas214533_atBronchialEpithelialCells4.8005.140Details
BioGPS Gene Atlas214533_atCD105+_Endothelial5.0005.140Details
BioGPS Gene Atlas214533_atCD14+_Monocytes5.4005.140Details
BioGPS Gene Atlas214533_atCD19+_BCells(neg._sel.)5.3005.140Details
BioGPS Gene Atlas214533_atCD33+_Myeloid6.3005.140Details
BioGPS Gene Atlas214533_atCD34+6.3005.140Details
BioGPS Gene Atlas214533_atCD4+_Tcells5.2005.140Details
BioGPS Gene Atlas214533_atCD56+_NKCells5.8505.140Details
BioGPS Gene Atlas214533_atCD71+_EarlyErythroid4.7005.140Details
BioGPS Gene Atlas214533_atCD8+_Tcells4.6505.140Details
BioGPS Gene Atlas214533_atCardiacMyocytes6.9505.140Details
BioGPS Gene Atlas214533_atCaudatenucleus4.5005.140Details
BioGPS Gene Atlas214533_atCerebellum4.1005.140Details
BioGPS Gene Atlas214533_atCerebellumPeduncles5.7005.140Details
BioGPS Gene Atlas214533_atCiliaryGanglion3.7505.140Details
BioGPS Gene Atlas214533_atCingulateCortex5.3005.140Details
BioGPS Gene Atlas214533_atColorectaladenocarcinoma5.0005.140Details
BioGPS Gene Atlas214533_atDorsalRootGanglion4.2505.140Details
BioGPS Gene Atlas214533_atFetalThyroid4.9005.140Details
BioGPS Gene Atlas214533_atFetalbrain4.8005.140Details
BioGPS Gene Atlas214533_atFetalliver4.4005.140Details
BioGPS Gene Atlas214533_atFetallung4.0005.140Details
BioGPS Gene Atlas214533_atGlobusPallidus4.0505.140Details
BioGPS Gene Atlas214533_atHeart6.8505.140Details
BioGPS Gene Atlas214533_atHypothalamus5.4505.140Details
BioGPS Gene Atlas214533_atKidney4.3505.140Details
BioGPS Gene Atlas214533_atLeukemia_chronicMyelogenousK-5624.5005.140Details
BioGPS Gene Atlas214533_atLeukemia_promyelocytic-HL-604.4505.140Details
BioGPS Gene Atlas214533_atLeukemialymphoblastic(MOLT-4)3.9505.140Details
BioGPS Gene Atlas214533_atLiver6.8505.140Details
BioGPS Gene Atlas214533_atLung5.4005.140Details
BioGPS Gene Atlas214533_atLymphnode4.2505.140Details
BioGPS Gene Atlas214533_atLymphoma_burkitts(Daudi)6.5005.140Details
BioGPS Gene Atlas214533_atLymphoma_burkitts(Raji)7.5005.140Details
BioGPS Gene Atlas214533_atMedullaOblongata4.5005.140Details
BioGPS Gene Atlas214533_atOccipitalLobe4.5505.140Details
BioGPS Gene Atlas214533_atOlfactoryBulb3.9005.140Details
BioGPS Gene Atlas214533_atOvary3.4005.140Details
BioGPS Gene Atlas214533_atPancreas4.1005.140Details
BioGPS Gene Atlas214533_atPancreaticIslet5.3005.140Details
BioGPS Gene Atlas214533_atParietalLobe5.6005.140Details
BioGPS Gene Atlas214533_atPituitary5.8505.140Details
BioGPS Gene Atlas214533_atPlacenta5.1005.140Details
BioGPS Gene Atlas214533_atPons4.8505.140Details
BioGPS Gene Atlas214533_atPrefrontalCortex6.1005.140Details
BioGPS Gene Atlas214533_atProstate5.8505.140Details
BioGPS Gene Atlas214533_atSalivarygland4.0505.140Details
BioGPS Gene Atlas214533_atSkeletalMuscle7.2005.140Details
BioGPS Gene Atlas214533_atSkin4.4505.140Details
BioGPS Gene Atlas214533_atSmoothMuscle5.6005.140Details
BioGPS Gene Atlas214533_atSpinalcord5.3505.140Details
BioGPS Gene Atlas214533_atSubthalamicNucleus4.7505.140Details
BioGPS Gene Atlas214533_atSuperiorCervicalGanglion6.2005.140Details
BioGPS Gene Atlas214533_atTemporalLobe4.7505.140Details
BioGPS Gene Atlas214533_atTestis4.2505.140Details
BioGPS Gene Atlas214533_atTestisGermCell4.0505.140Details
BioGPS Gene Atlas214533_atTestisIntersitial4.1505.140Details
BioGPS Gene Atlas214533_atTestisLeydigCell5.1005.140Details
BioGPS Gene Atlas214533_atTestisSeminiferousTubule4.2005.140Details
BioGPS Gene Atlas214533_atThalamus5.1005.140Details
BioGPS Gene Atlas214533_atThymus3.8505.140Details
BioGPS Gene Atlas214533_atThyroid6.1505.140Details
BioGPS Gene Atlas214533_atTongue5.1005.140Details
BioGPS Gene Atlas214533_atTonsil4.9005.140Details
BioGPS Gene Atlas214533_atTrachea4.1005.140Details
BioGPS Gene Atlas214533_atTrigeminalGanglion5.9505.140Details
BioGPS Gene Atlas214533_atUterus4.0005.140Details
BioGPS Gene Atlas214533_atUterusCorpus5.1505.140Details
BioGPS Gene Atlas214533_atWholeBlood5.3505.140Details
BioGPS Gene Atlas214533_atWholebrain4.1005.140Details
BioGPS Gene Atlas214533_atcolon5.0505.140Details
BioGPS Gene Atlas214533_atpineal_day6.1405.140Details
BioGPS Gene Atlas214533_atpineal_night6.0405.140Details
BioGPS Gene Atlas214533_atretina6.0005.140Details
BioGPS Gene Atlas214533_atsmall_intestine4.7505.140Details
BioGPS NCI60214533_at7865.2295.050Details
BioGPS NCI60214533_atA1724.7315.050Details
BioGPS NCI60214533_atA2044.9795.050Details
BioGPS NCI60214533_atA3615.1005.050Details
BioGPS NCI60214533_atA4985.0125.050Details
BioGPS NCI60214533_atA5495.1685.050Details
BioGPS NCI60214533_atACC35.3105.050Details
BioGPS NCI60214533_atACHN4.5535.050Details
BioGPS NCI60214533_atALVA315.4825.050Details
BioGPS NCI60214533_atCAKI15.3175.050Details
BioGPS NCI60214533_atCCRT CEM6.2865.050Details
BioGPS NCI60214533_atCOLO2055.0815.050Details
BioGPS NCI60214533_atDLD14.8935.050Details
BioGPS NCI60214533_atDU1454.8485.050Details
BioGPS NCI60214533_atEKVX4.7535.050Details
BioGPS NCI60214533_atGM1335.1645.050Details
BioGPS NCI60214533_atGM16005.3385.050Details
BioGPS NCI60214533_atGM23135.1355.050Details
BioGPS NCI60214533_atGM23455.0425.050Details
BioGPS NCI60214533_atGM24935.4605.050Details
BioGPS NCI60214533_atGM975.8295.050Details
BioGPS NCI60214533_atHCC29984.5175.050Details
BioGPS NCI60214533_atHCT1165.0295.050Details
BioGPS NCI60214533_atHCT154.6475.050Details
BioGPS NCI60214533_atHEK 293 T-rex5.2685.050Details
BioGPS NCI60214533_atHEK 293T4.9815.050Details
BioGPS NCI60214533_atHEK2934.9955.050Details
BioGPS NCI60214533_atHELA4.6825.050Details
BioGPS NCI60214533_atHEPG25.0215.050Details
BioGPS NCI60214533_atHL605.4235.050Details
BioGPS NCI60214533_atHOP625.0205.050Details
BioGPS NCI60214533_atHOP924.8075.050Details
BioGPS NCI60214533_atHS578T4.9115.050Details
BioGPS NCI60214533_atHSG4.8035.050Details
BioGPS NCI60214533_atHT10804.9235.050Details
BioGPS NCI60214533_atHT295.5615.050Details
BioGPS NCI60214533_atIGROV14.9425.050Details
BioGPS NCI60214533_atIOSE804.9785.050Details
BioGPS NCI60214533_atJURKAT5.0115.050Details
BioGPS NCI60214533_atK5625.6855.050Details
BioGPS NCI60214533_atKM125.2865.050Details
BioGPS NCI60214533_atLN184.6615.050Details
BioGPS NCI60214533_atLNCAP5.0295.050Details
BioGPS NCI60214533_atLOX IMVI5.0145.050Details
BioGPS NCI60214533_atM144.9775.050Details
BioGPS NCI60214533_atMALME 3M5.5815.050Details
BioGPS NCI60214533_atMCF74.8255.050Details
BioGPS NCI60214533_atMD MB2315.1255.050Details
BioGPS NCI60214533_atMDA MB4355.5605.050Details
BioGPS NCI60214533_atMOLT45.2325.050Details
BioGPS NCI60214533_atNCI 4605.1605.050Details
BioGPS NCI60214533_atNCI H2265.2215.050Details
BioGPS NCI60214533_atNCI H235.0095.050Details
BioGPS NCI60214533_atNCI H322M4.9925.050Details
BioGPS NCI60214533_atNCVADR RES4.6595.050Details
BioGPS NCI60214533_atOVCAR35.3515.050Details
BioGPS NCI60214533_atOVCAR44.9995.050Details
BioGPS NCI60214533_atOVCAR54.9015.050Details
BioGPS NCI60214533_atOVCAR84.6355.050Details
BioGPS NCI60214533_atPANC15.1135.050Details
BioGPS NCI60214533_atRL75.1695.050Details
BioGPS NCI60214533_atRPMI 82265.1805.050Details
BioGPS NCI60214533_atRS118465.4095.050Details
BioGPS NCI60214533_atRXF3934.9955.050Details
BioGPS NCI60214533_atSAOS25.0815.050Details
BioGPS NCI60214533_atSF2685.0105.050Details
BioGPS NCI60214533_atSF2954.8825.050Details
BioGPS NCI60214533_atSF5394.6615.050Details
BioGPS NCI60214533_atSHSYSY+RA4.7925.050Details
BioGPS NCI60214533_atSHSYSY-RA4.9155.050Details
BioGPS NCI60214533_atSKMEL24.9955.050Details
BioGPS NCI60214533_atSKMEL285.0265.050Details
BioGPS NCI60214533_atSKMEL54.7315.050Details
BioGPS NCI60214533_atSKOV35.2905.050Details
BioGPS NCI60214533_atSN12C4.9635.050Details
BioGPS NCI60214533_atSNB194.6375.050Details
BioGPS NCI60214533_atSNB754.9405.050Details
BioGPS NCI60214533_atSR5.2355.050Details
BioGPS NCI60214533_atSW6205.1015.050Details
BioGPS NCI60214533_atT245.1695.050Details
BioGPS NCI60214533_atT3M45.2695.050Details
BioGPS NCI60214533_atTK104.9875.050Details
BioGPS NCI60214533_atU1184.8595.050Details
BioGPS NCI60214533_atU1384.6415.050Details
BioGPS NCI60214533_atU20S4.8615.050Details
BioGPS NCI60214533_atU2514.8965.050Details
BioGPS NCI60214533_atU874.8325.050Details
BioGPS NCI60214533_atUACC2574.8825.050Details
BioGPS NCI60214533_atUACC625.1265.050Details
BioGPS NCI60214533_atUO314.8045.050Details
BioGPS NCI60214533_atZR75_15.2365.050Details
BioGPS NCI60214533_atastrocytes5.0445.050Details
BioGPS NCI60214533_athuh-75.2715.050Details