Search Antibody, Protein, and ELISA Kit Solutions


Gene ID: 63967 | CLSPN Antibody Resource


CLSPN Antibody Resource
Gene Full Name: 
claspin
Uniprot: 
Q9HAW4
Protein Name: 
claspin
Nucleotide: 
XM_005271105
Alias: 
Ensembl: 
ENSG00000092853
Location: 
1p34.2
HPRD: 
09257
NCBI Gene: 
63967
MIM: 
605434

Summary: 
The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Function: 
Required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation. Adapter protein which binds to BRCA1 and the checkpoint kinase CHEK1 and facilitates the ATR-dependent phosphorylation of both proteins. Can also bind specifically to branched DNA structures and may associate with S-phase chromatin following formation of the pre-replication complex (pre-RC). This may indicate a role for this protein as a sensor which monitors the integrity of DNA replication forks.
Subcellular location: 
Nucleus .
PTM: 
Acetylation;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OASA07628 CLSPN Antibody (OASA07628) Human IP, WB 50ug $395 Details
Blocking Peptide OESA09433 CLASPIN BLOCKING PEPTIDE (50ug) Human 50ug $245 Details
Polyclonal Antibody ARP61516_P050 CLSPN Antibody (ARP61516_P050) Polyclonal Human, Pig Not tested 50 ug $125 Details
Polyclonal Antibody ARP61517_P050 CLSPN Antibody (ARP61517_P050) Polyclonal Not tested 50 ug $125 Details

Show all CLSPN antibodies


Product Images
CLSPN Protocols
Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP61517 African elephant CLSPN antibody; Loxodonta africana CLSPN antibody G3T0V2 92.0%
ARP61517 Bovine CLSPN antibody; Bos taurus CLSPN antibody E1BIR1 100.0%
ARP34931 Bovine CLSPN antibody; Bos taurus CLSPN antibody E1BIR1 79.0%
ARP61516 Cat CLSPN antibody; Felis catus CLSPN antibody M3WJN4 85.0%
ARP61517 Cat CLSPN antibody; Felis catus CLSPN antibody M3WJN4 85.0%
ARP34931 Cat CLSPN antibody; Felis catus CLSPN antibody M3WJN4 79.0%
ARP61516 Chimpanzee CLSPN antibody; Pan troglodytes CLSPN antibody H2R4F8 100.0%
ARP61517 Chimpanzee CLSPN antibody; Pan troglodytes CLSPN antibody H2R4F8 100.0%
ARP34931 Chimpanzee CLSPN antibody; Pan troglodytes CLSPN antibody H2R4F8 79.0%
ARP61517 Dog CLSPN antibody; Canis familiaris CLSPN antibody E2QWW0 85.0%
ARP34931 Dog CLSPN antibody; Canis familiaris CLSPN antibody E2QWW0 79.0%
ARP61517 European domestic ferret CLSPN antibody; Mustela putorius furo CLSPN antibody M3YTW0 92.0%
ARP61516 European domestic ferret CLSPN antibody; Mustela putorius furo CLSPN antibody M3YTW0 85.0%
ARP34931 European domestic ferret CLSPN antibody; Mustela putorius furo CLSPN antibody M3YTW0 79.0%
ARP61517 Giant panda CLSPN antibody; Ailuropoda melanoleuca CLSPN antibody G1L1I5 92.0%
ARP61516 Giant panda CLSPN antibody; Ailuropoda melanoleuca CLSPN antibody G1L1I5 85.0%
ARP34931 Giant panda CLSPN antibody; Ailuropoda melanoleuca CLSPN antibody G1L1I5 79.0%
ARP61517 Horse CLSPN antibody; Equus caballus CLSPN antibody F6ZPJ4 92.0%
ARP34931 Horse CLSPN antibody; Equus caballus CLSPN antibody F6ZPJ4 79.0%
ARP61516 Human CLSPN antibody; Homo sapiens CLSPN antibody Q05D30 100.0%
ARP61516 Human CLSPN antibody; Homo sapiens CLSPN antibody Q1RMC5 100.0%
ARP61517 Human CLSPN antibody; Homo sapiens CLSPN antibody Q1RMC5 100.0%
ARP61516 Human CLSPN antibody; Homo sapiens CLSPN antibody Q9HAW4-2 100.0%
ARP61517 Human CLSPN antibody; Homo sapiens CLSPN antibody Q9HAW4-2 100.0%
ARP61516 Human CLSPN antibody; Homo sapiens CLSPN antibody Q9HAW4-3 100.0%
ARP61517 Human CLSPN antibody; Homo sapiens CLSPN antibody Q9HAW4-3 100.0%
ARP61516 Human CLSPN antibody; Homo sapiens CLSPN antibody Q9HAW4 100.0%
ARP61517 Human CLSPN antibody; Homo sapiens CLSPN antibody Q9HAW4 100.0%
ARP61516 Human CLSPN antibody; Homo sapiens CLSPN antibody E7ESG2 100.0%
ARP61517 Human CLSPN antibody; Homo sapiens CLSPN antibody E7ESG2 100.0%
ARP34931 Human CLSPN antibody; Homo sapiens CLSPN antibody Q05D30 79.0%
ARP34931 Human CLSPN antibody; Homo sapiens CLSPN antibody Q9HAW4-2 79.0%
ARP34931 Human CLSPN antibody; Homo sapiens CLSPN antibody Q9HAW4-3 79.0%
ARP34931 Human CLSPN antibody; Homo sapiens CLSPN antibody Q9HAW4 79.0%
ARP34931 Human CLSPN antibody; Homo sapiens CLSPN antibody E7ESG2 79.0%
ARP34931 Mouse CLSPN antibody; Mus musculus CLSPN antibody Q80YR7 79.0%
ARP34931 Mouse CLSPN antibody; Mus musculus CLSPN antibody F6S522 79.0%
ARP61517 Northern white-cheeked gibbon CLSPN antibody; Nomascus leucogenys CLSPN antibody G1RJU6 100.0%
ARP61516 Northern white-cheeked gibbon CLSPN antibody; Nomascus leucogenys CLSPN antibody G1RJU6 93.0%
ARP61516 Pig CLSPN antibody; Sus scrofa CLSPN antibody F1SV65 85.0%
ARP61517 Pig CLSPN antibody; Sus scrofa CLSPN antibody F1SV65 85.0%
ARP34931 Pig CLSPN antibody; Sus scrofa CLSPN antibody F1SV65 79.0%
ARP61517 Rabbit CLSPN antibody; Oryctolagus cuniculus CLSPN antibody G1TDL8 85.0%
ARP34931 Rat CLSPN antibody; Rattus norvegicus CLSPN antibody D3ZHC3 79.0%
ARP61517 Rhesus macaque CLSPN antibody; Macaca mulatta CLSPN antibody H9ZC87 100.0%
ARP61516 Rhesus macaque CLSPN antibody; Macaca mulatta CLSPN antibody H9ZC87 93.0%
ARP61516 Rhesus macaque CLSPN antibody; Macaca mulatta CLSPN antibody F7GG77 93.0%
ARP34931 Rhesus macaque CLSPN antibody; Macaca mulatta CLSPN antibody H9ZC87 79.0%
ARP34931 Rhesus macaque CLSPN antibody; Macaca mulatta CLSPN antibody F7GG77 79.0%
ARP61517 Small-eared galago CLSPN antibody; Otolemur garnettii CLSPN antibody H0WPH1 85.0%
ARP34931 Small-eared galago CLSPN antibody; Otolemur garnettii CLSPN antibody H0WPH1 79.0%
ARP61517 Sumatran orangutan CLSPN antibody; Pongo abelii CLSPN antibody H2N808 93.0%
ARP61516 Sumatran orangutan CLSPN antibody; Pongo abelii CLSPN antibody H2N808 86.0%
ARP34931 Sumatran orangutan CLSPN antibody; Pongo abelii CLSPN antibody H2N808 79.0%
ARP34931 Tasmanian devil CLSPN antibody; Sarcophilus harrisii CLSPN antibody G3WXU3 79.0%
ARP31598 Thirteen-lined ground squirrel CLSPN antibody; Spermophilus tridecemlineatus CLSPN antibody I3NCJ6 90.0%
ARP34931 Thirteen-lined ground squirrel CLSPN antibody; Spermophilus tridecemlineatus CLSPN antibody I3NCJ6 79.0%
ARP61517 White-tufted-ear marmoset CLSPN antibody; Callithrix jacchus CLSPN antibody F7I949 93.0%
ARP61517 White-tufted-ear marmoset CLSPN antibody; Callithrix jacchus CLSPN antibody F7I926 93.0%
ARP61517 White-tufted-ear marmoset CLSPN antibody; Callithrix jacchus CLSPN antibody F7I945 93.0%
ARP61516 White-tufted-ear marmoset CLSPN antibody; Callithrix jacchus CLSPN antibody F7I949 79.0%
ARP61516 White-tufted-ear marmoset CLSPN antibody; Callithrix jacchus CLSPN antibody F7I926 79.0%
ARP61516 White-tufted-ear marmoset CLSPN antibody; Callithrix jacchus CLSPN antibody F7I945 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas219621_at721_B_lymphoblasts10.60012.320Details
BioGPS Gene Atlas219621_atAdipocyte10.50012.320Details
BioGPS Gene Atlas219621_atAdrenalCortex15.70012.320Details
BioGPS Gene Atlas219621_atAdrenalgland10.45012.320Details
BioGPS Gene Atlas219621_atAmygdala10.50012.320Details
BioGPS Gene Atlas219621_atAppendix19.00012.320Details
BioGPS Gene Atlas219621_atAtrioventricularNode11.85012.320Details
BioGPS Gene Atlas219621_atBDCA4+_DentriticCells9.20012.320Details
BioGPS Gene Atlas219621_atBonemarrow12.70012.320Details
BioGPS Gene Atlas219621_atBronchialEpithelialCells9.50012.320Details
BioGPS Gene Atlas219621_atCD105+_Endothelial10.35012.320Details
BioGPS Gene Atlas219621_atCD14+_Monocytes10.70012.320Details
BioGPS Gene Atlas219621_atCD19+_BCells(neg._sel.)10.75012.320Details
BioGPS Gene Atlas219621_atCD33+_Myeloid12.35012.320Details
BioGPS Gene Atlas219621_atCD34+13.05012.320Details
BioGPS Gene Atlas219621_atCD4+_Tcells9.90012.320Details
BioGPS Gene Atlas219621_atCD56+_NKCells11.65012.320Details
BioGPS Gene Atlas219621_atCD71+_EarlyErythroid10.85012.320Details
BioGPS Gene Atlas219621_atCD8+_Tcells7.15012.320Details
BioGPS Gene Atlas219621_atCardiacMyocytes19.30012.320Details
BioGPS Gene Atlas219621_atCaudatenucleus9.90012.320Details
BioGPS Gene Atlas219621_atCerebellum9.25012.320Details
BioGPS Gene Atlas219621_atCerebellumPeduncles15.15012.320Details
BioGPS Gene Atlas219621_atCiliaryGanglion10.20012.320Details
BioGPS Gene Atlas219621_atCingulateCortex14.90012.320Details
BioGPS Gene Atlas219621_atColorectaladenocarcinoma10.45012.320Details
BioGPS Gene Atlas219621_atDorsalRootGanglion14.50012.320Details
BioGPS Gene Atlas219621_atFetalThyroid11.30012.320Details
BioGPS Gene Atlas219621_atFetalbrain10.30012.320Details
BioGPS Gene Atlas219621_atFetalliver10.40012.320Details
BioGPS Gene Atlas219621_atFetallung7.40012.320Details
BioGPS Gene Atlas219621_atGlobusPallidus9.85012.320Details
BioGPS Gene Atlas219621_atHeart20.05012.320Details
BioGPS Gene Atlas219621_atHypothalamus11.05012.320Details
BioGPS Gene Atlas219621_atKidney12.50012.320Details
BioGPS Gene Atlas219621_atLeukemia_chronicMyelogenousK-56210.00012.320Details
BioGPS Gene Atlas219621_atLeukemia_promyelocytic-HL-6010.45012.320Details
BioGPS Gene Atlas219621_atLeukemialymphoblastic(MOLT-4)9.55012.320Details
BioGPS Gene Atlas219621_atLiver18.15012.320Details
BioGPS Gene Atlas219621_atLung11.05012.320Details
BioGPS Gene Atlas219621_atLymphnode10.15012.320Details
BioGPS Gene Atlas219621_atLymphoma_burkitts(Daudi)14.90012.320Details
BioGPS Gene Atlas219621_atLymphoma_burkitts(Raji)17.40012.320Details
BioGPS Gene Atlas219621_atMedullaOblongata17.05012.320Details
BioGPS Gene Atlas219621_atOccipitalLobe9.75012.320Details
BioGPS Gene Atlas219621_atOlfactoryBulb8.20012.320Details
BioGPS Gene Atlas219621_atOvary8.20012.320Details
BioGPS Gene Atlas219621_atPancreas9.40012.320Details
BioGPS Gene Atlas219621_atPancreaticIslet11.85012.320Details
BioGPS Gene Atlas219621_atParietalLobe13.80012.320Details
BioGPS Gene Atlas219621_atPituitary14.75012.320Details
BioGPS Gene Atlas219621_atPlacenta10.30012.320Details
BioGPS Gene Atlas219621_atPons24.70012.320Details
BioGPS Gene Atlas219621_atPrefrontalCortex12.45012.320Details
BioGPS Gene Atlas219621_atProstate12.10012.320Details
BioGPS Gene Atlas219621_atSalivarygland9.70012.320Details
BioGPS Gene Atlas219621_atSkeletalMuscle32.75012.320Details
BioGPS Gene Atlas219621_atSkin13.15012.320Details
BioGPS Gene Atlas219621_atSmoothMuscle7.55012.320Details
BioGPS Gene Atlas219621_atSpinalcord19.40012.320Details
BioGPS Gene Atlas219621_atSubthalamicNucleus11.35012.320Details
BioGPS Gene Atlas219621_atSuperiorCervicalGanglion21.55012.320Details
BioGPS Gene Atlas219621_atTemporalLobe16.85012.320Details
BioGPS Gene Atlas219621_atTestis9.35012.320Details
BioGPS Gene Atlas219621_atTestisGermCell8.80012.320Details
BioGPS Gene Atlas219621_atTestisIntersitial9.45012.320Details
BioGPS Gene Atlas219621_atTestisLeydigCell12.20012.320Details
BioGPS Gene Atlas219621_atTestisSeminiferousTubule9.35012.320Details
BioGPS Gene Atlas219621_atThalamus12.25012.320Details
BioGPS Gene Atlas219621_atThymus7.55012.320Details
BioGPS Gene Atlas219621_atThyroid11.80012.320Details
BioGPS Gene Atlas219621_atTongue15.00012.320Details
BioGPS Gene Atlas219621_atTonsil11.00012.320Details
BioGPS Gene Atlas219621_atTrachea9.00012.320Details
BioGPS Gene Atlas219621_atTrigeminalGanglion19.25012.320Details
BioGPS Gene Atlas219621_atUterus6.90012.320Details
BioGPS Gene Atlas219621_atUterusCorpus15.35012.320Details
BioGPS Gene Atlas219621_atWholeBlood10.85012.320Details
BioGPS Gene Atlas219621_atWholebrain8.20012.320Details
BioGPS Gene Atlas219621_atcolon10.75012.320Details
BioGPS Gene Atlas219621_atpineal_day12.52012.320Details
BioGPS Gene Atlas219621_atpineal_night12.28012.320Details
BioGPS Gene Atlas219621_atretina12.42512.320Details
BioGPS Gene Atlas219621_atsmall_intestine10.20012.320Details
BioGPS NCI60219621_at7868.5658.620Details
BioGPS NCI60219621_atA1726.8678.620Details
BioGPS NCI60219621_atA2047.9118.620Details
BioGPS NCI60219621_atA3618.1688.620Details
BioGPS NCI60219621_atA4987.8648.620Details
BioGPS NCI60219621_atA5498.3668.620Details
BioGPS NCI60219621_atACC39.8038.620Details
BioGPS NCI60219621_atACHN6.9768.620Details
BioGPS NCI60219621_atALVA3110.3048.620Details
BioGPS NCI60219621_atCAKI18.9348.620Details
BioGPS NCI60219621_atCCRT CEM18.0398.620Details
BioGPS NCI60219621_atCOLO2058.1288.620Details
BioGPS NCI60219621_atDLD17.7548.620Details
BioGPS NCI60219621_atDU1457.2788.620Details
BioGPS NCI60219621_atEKVX7.1398.620Details
BioGPS NCI60219621_atGM1338.4788.620Details
BioGPS NCI60219621_atGM16009.6998.620Details
BioGPS NCI60219621_atGM23138.6908.620Details
BioGPS NCI60219621_atGM23457.8588.620Details
BioGPS NCI60219621_atGM249312.3098.620Details
BioGPS NCI60219621_atGM9715.5928.620Details
BioGPS NCI60219621_atHCC29986.4638.620Details
BioGPS NCI60219621_atHCT1168.0748.620Details
BioGPS NCI60219621_atHCT156.1988.620Details
BioGPS NCI60219621_atHEK 293 T-rex9.8498.620Details
BioGPS NCI60219621_atHEK 293T7.5618.620Details
BioGPS NCI60219621_atHEK2937.7798.620Details
BioGPS NCI60219621_atHELA6.7978.620Details
BioGPS NCI60219621_atHEPG28.4728.620Details
BioGPS NCI60219621_atHL6016.7378.620Details
BioGPS NCI60219621_atHOP628.0098.620Details
BioGPS NCI60219621_atHOP927.4538.620Details
BioGPS NCI60219621_atHS578T7.8058.620Details
BioGPS NCI60219621_atHSG7.3358.620Details
BioGPS NCI60219621_atHT10807.7558.620Details
BioGPS NCI60219621_atHT2910.3098.620Details
BioGPS NCI60219621_atIGROV17.7948.620Details
BioGPS NCI60219621_atIOSE807.9288.620Details
BioGPS NCI60219621_atJURKAT10.2448.620Details
BioGPS NCI60219621_atK56215.9088.620Details
BioGPS NCI60219621_atKM129.0698.620Details
BioGPS NCI60219621_atLN186.1518.620Details
BioGPS NCI60219621_atLNCAP8.0358.620Details
BioGPS NCI60219621_atLOX IMVI7.8898.620Details
BioGPS NCI60219621_atM147.6598.620Details
BioGPS NCI60219621_atMALME 3M12.3788.620Details
BioGPS NCI60219621_atMCF77.4038.620Details
BioGPS NCI60219621_atMD MB23115.2158.620Details
BioGPS NCI60219621_atMDA MB43510.7828.620Details
BioGPS NCI60219621_atMOLT49.0178.620Details
BioGPS NCI60219621_atNCI 4608.6688.620Details
BioGPS NCI60219621_atNCI H2269.4668.620Details
BioGPS NCI60219621_atNCI H237.9528.620Details
BioGPS NCI60219621_atNCI H322M7.8458.620Details
BioGPS NCI60219621_atNCVADR RES6.7748.620Details
BioGPS NCI60219621_atOVCAR39.3868.620Details
BioGPS NCI60219621_atOVCAR47.8278.620Details
BioGPS NCI60219621_atOVCAR57.5108.620Details
BioGPS NCI60219621_atOVCAR86.8048.620Details
BioGPS NCI60219621_atPANC18.3938.620Details
BioGPS NCI60219621_atRL78.6248.620Details
BioGPS NCI60219621_atRPMI 82268.5718.620Details
BioGPS NCI60219621_atRS1184612.0738.620Details
BioGPS NCI60219621_atRXF3937.9898.620Details
BioGPS NCI60219621_atSAOS28.1158.620Details
BioGPS NCI60219621_atSF2687.8518.620Details
BioGPS NCI60219621_atSF2957.3748.620Details
BioGPS NCI60219621_atSF5396.9598.620Details
BioGPS NCI60219621_atSHSYSY+RA6.6578.620Details
BioGPS NCI60219621_atSHSYSY-RA7.7268.620Details
BioGPS NCI60219621_atSKMEL27.7018.620Details
BioGPS NCI60219621_atSKMEL288.0278.620Details
BioGPS NCI60219621_atSKMEL57.0418.620Details
BioGPS NCI60219621_atSKOV38.8288.620Details
BioGPS NCI60219621_atSN12C7.6148.620Details
BioGPS NCI60219621_atSNB196.7428.620Details
BioGPS NCI60219621_atSNB757.6458.620Details
BioGPS NCI60219621_atSR10.3418.620Details
BioGPS NCI60219621_atSW6208.4898.620Details
BioGPS NCI60219621_atT248.4658.620Details
BioGPS NCI60219621_atT3M49.8548.620Details
BioGPS NCI60219621_atTK1013.8918.620Details
BioGPS NCI60219621_atU1186.6438.620Details
BioGPS NCI60219621_atU1386.0298.620Details
BioGPS NCI60219621_atU20S7.4268.620Details
BioGPS NCI60219621_atU2517.6438.620Details
BioGPS NCI60219621_atU876.3788.620Details
BioGPS NCI60219621_atUACC2577.4068.620Details
BioGPS NCI60219621_atUACC628.3918.620Details
BioGPS NCI60219621_atUO316.9168.620Details
BioGPS NCI60219621_atZR75_110.2838.620Details
BioGPS NCI60219621_atastrocytes7.8868.620Details
BioGPS NCI60219621_athuh-78.5378.620Details