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Gene ID: 10978 | CLP1 Antibody Resource


CLP1 Antibody Resource
Gene Full Name: 
cleavage and polyadenylation factor I subunit 1
Uniprot: 
Q92989
Protein Name: 
polyribonucleotide 5'-hydroxyl-kinase Clp1
Nucleotide: 
NM_006831
Alias: 
HEAB;hClp1;
Ensembl: 
ENSG00000172409
Location: 
11q12
HPRD: 
16382
NCBI Gene: 
10978
MIM: 
608757

Summary: 
Function: 
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double-stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.
Subcellular location: 
Nucleus .
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP64201_P050 CLP1 antibody - C-terminal region (ARP64201_P050) Human WB 50ug $289 Details
Polyclonal Antibody ARP64202_P050 CLP1 antibody - N-terminal region (ARP64202_P050) Human WB 50ug $289 Details
Polyclonal Antibody OAAB12558 CLP1 antibody - C - terminal region (OAAB12558) Human WB 400ul $289 Details
Polyclonal Antibody OAGA01121 CLP1 antibody (OAGA01121) Polyclonal Human ICC/IF, IHC (Formalin-fixed paraffin-embedded sections), WB 100 ul $340 Details

Show all CLP1 antibodies


Product Images
CLP1 antibody - C-terminal region (ARP64201_P050) in RPMI-8226 cells using Western Blot

Sample Type: RPMI-8226

CLP1 antibody - N-terminal region (ARP64202_P050) in Human HepG2 cells using Western Blot

Sample Type: Human HepG2

CLP1 antibody - C - terminal region (OAAB12558) in HepG2 cells using Western Blot

Sample Type: HepG2


CLP1 Protocols

Publications

Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP64202 African clawed frog CLP1 antibody; Xenopus laevis CLP1 antibody Q6NS21 83.0%
ARP64202 Black flying fox CLP1 antibody; Pteropus alecto CLP1 antibody L5L280 100.0%
ARP64202 Bovine CLP1 antibody; Bos taurus CLP1 antibody A2VE01 100.0%
ARP64202 Brandt's bat CLP1 antibody; Myotis brandtii CLP1 antibody S7NRC4 93.0%
ARP64202 Cat CLP1 antibody; Felis catus CLP1 antibody M3W686 100.0%
ARP64202 Chicken CLP1 antibody; Gallus gallus CLP1 antibody Q5ZJL4 86.0%
ARP64202 Chicken CLP1 antibody; Gallus gallus CLP1 antibody F1NA64 86.0%
ARP64202 Chinese softshell turtle CLP1 antibody; Pelodiscus sinensis CLP1 antibody K7FCX5 79.0%
ARP64202 Chinese tree shrew CLP1 antibody; Tupaia chinensis CLP1 antibody L9J8N7 100.0%
ARP64202 Collared flycatcher CLP1 antibody; Ficedula albicollis CLP1 antibody U3K9D2 86.0%
ARP64202 Crab-eating macaque CLP1 antibody; Macaca fascicularis CLP1 antibody Q4R7R3 100.0%
ARP64202 David's myotis CLP1 antibody; Myotis davidii CLP1 antibody L5LCM5 100.0%
ARP64202 Dog CLP1 antibody; Canis familiaris CLP1 antibody E2R321 100.0%
ARP64202 European domestic ferret CLP1 antibody; Mustela putorius furo CLP1 antibody M3XMG6 100.0%
ARP64202 Giant panda CLP1 antibody; Ailuropoda melanoleuca CLP1 antibody G1M7K5 100.0%
ARP64202 Green sea-turtle CLP1 antibody; Chelonia mydas CLP1 antibody M7B671 86.0%
ARP64202 Horse CLP1 antibody; Equus caballus CLP1 antibody F7BH56 100.0%
ARP64202 Human CLP1 antibody; Homo sapiens CLP1 antibody Q92989-2 100.0%
ARP64202 Human CLP1 antibody; Homo sapiens CLP1 antibody Q92989 100.0%
ARP64202 Human CLP1 antibody; Homo sapiens CLP1 antibody E9PJM4 100.0%
ARP64202 Human CLP1 antibody; Homo sapiens CLP1 antibody E9PL17 100.0%
ARP64202 Mouse CLP1 antibody; Mus musculus CLP1 antibody Q3TEC7 100.0%
ARP64202 Mouse CLP1 antibody; Mus musculus CLP1 antibody Q3ULZ9 100.0%
ARP64202 Mouse CLP1 antibody; Mus musculus CLP1 antibody Q99LI9 100.0%
ARP64202 Pig CLP1 antibody; Sus scrofa CLP1 antibody F2Z5N4 100.0%
ARP64202 Rabbit CLP1 antibody; Oryctolagus cuniculus CLP1 antibody G1SS89 100.0%
ARP64202 Rat CLP1 antibody; Rattus norvegicus CLP1 antibody Q5PQL4 100.0%
ARP64202 Rhesus macaque CLP1 antibody; Macaca mulatta CLP1 antibody F6QNV8 100.0%
ARP64202 Sea lamprey CLP1 antibody; Petromyzon marinus CLP1 antibody S4RQB7 85.0%
ARP64202 Small-eared galago CLP1 antibody; Otolemur garnettii CLP1 antibody H0WQ20 100.0%
ARP64202 Southern platyfish CLP1 antibody; Xiphophorus maculatus CLP1 antibody M4A5R1 79.0%
ARP64202 Tasmanian devil CLP1 antibody; Sarcophilus harrisii CLP1 antibody G3WST1 93.0%
ARP64202 Thirteen-lined ground squirrel CLP1 antibody; Spermophilus tridecemlineatus CLP1 antibody I3N8Y4 100.0%
ARP64202 timber rattlesnake CLP1 antibody; Crotalus horridus CLP1 antibody T1DLU9 79.0%
ARP64202 Vampire bat CLP1 antibody; Desmodus rotundus CLP1 antibody K9J0T0 100.0%
ARP64202 West Indian ocean coelacanth CLP1 antibody; Latimeria chalumnae CLP1 antibody H3A1M6 79.0%
ARP64202 Western clawed frog CLP1 antibody; Xenopus tropicalis CLP1 antibody Q66JK4 79.0%
ARP64202 White-tufted-ear marmoset CLP1 antibody; Callithrix jacchus CLP1 antibody U3B8Z5 100.0%
ARP64202 White-tufted-ear marmoset CLP1 antibody; Callithrix jacchus CLP1 antibody F6VRZ5 100.0%
ARP64202 Zebra finch CLP1 antibody; Taeniopygia guttata CLP1 antibody H0Z9F0 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas204370_at721_B_lymphoblasts41.9009.210Details
BioGPS Gene Atlas204370_atAdipocyte8.3009.210Details
BioGPS Gene Atlas204370_atAdrenalCortex6.5009.210Details
BioGPS Gene Atlas204370_atAdrenalgland5.2009.210Details
BioGPS Gene Atlas204370_atAmygdala5.2509.210Details
BioGPS Gene Atlas204370_atAppendix13.4509.210Details
BioGPS Gene Atlas204370_atAtrioventricularNode5.3009.210Details
BioGPS Gene Atlas204370_atBDCA4+_DentriticCells44.5509.210Details
BioGPS Gene Atlas204370_atBonemarrow7.9509.210Details
BioGPS Gene Atlas204370_atBronchialEpithelialCells28.2509.210Details
BioGPS Gene Atlas204370_atCD105+_Endothelial14.4009.210Details
BioGPS Gene Atlas204370_atCD14+_Monocytes9.9009.210Details
BioGPS Gene Atlas204370_atCD19+_BCells(neg._sel.)15.6009.210Details
BioGPS Gene Atlas204370_atCD33+_Myeloid8.2009.210Details
BioGPS Gene Atlas204370_atCD34+12.9009.210Details
BioGPS Gene Atlas204370_atCD4+_Tcells6.8509.210Details
BioGPS Gene Atlas204370_atCD56+_NKCells32.8009.210Details
BioGPS Gene Atlas204370_atCD71+_EarlyErythroid5.9009.210Details
BioGPS Gene Atlas204370_atCD8+_Tcells6.4509.210Details
BioGPS Gene Atlas204370_atCardiacMyocytes8.0509.210Details
BioGPS Gene Atlas204370_atCaudatenucleus5.1009.210Details
BioGPS Gene Atlas204370_atCerebellum5.0009.210Details
BioGPS Gene Atlas204370_atCerebellumPeduncles7.0009.210Details
BioGPS Gene Atlas204370_atCiliaryGanglion4.4509.210Details
BioGPS Gene Atlas204370_atCingulateCortex6.2509.210Details
BioGPS Gene Atlas204370_atColorectaladenocarcinoma10.9009.210Details
BioGPS Gene Atlas204370_atDorsalRootGanglion4.8009.210Details
BioGPS Gene Atlas204370_atFetalThyroid5.9509.210Details
BioGPS Gene Atlas204370_atFetalbrain6.2009.210Details
BioGPS Gene Atlas204370_atFetalliver9.6009.210Details
BioGPS Gene Atlas204370_atFetallung5.3509.210Details
BioGPS Gene Atlas204370_atGlobusPallidus4.4509.210Details
BioGPS Gene Atlas204370_atHeart7.9009.210Details
BioGPS Gene Atlas204370_atHypothalamus6.9509.210Details
BioGPS Gene Atlas204370_atKidney5.0009.210Details
BioGPS Gene Atlas204370_atLeukemia_chronicMyelogenousK-56219.1509.210Details
BioGPS Gene Atlas204370_atLeukemia_promyelocytic-HL-608.6009.210Details
BioGPS Gene Atlas204370_atLeukemialymphoblastic(MOLT-4)14.9009.210Details
BioGPS Gene Atlas204370_atLiver8.2509.210Details
BioGPS Gene Atlas204370_atLung10.4009.210Details
BioGPS Gene Atlas204370_atLymphnode5.5009.210Details
BioGPS Gene Atlas204370_atLymphoma_burkitts(Daudi)12.7009.210Details
BioGPS Gene Atlas204370_atLymphoma_burkitts(Raji)9.6509.210Details
BioGPS Gene Atlas204370_atMedullaOblongata7.1009.210Details
BioGPS Gene Atlas204370_atOccipitalLobe5.3009.210Details
BioGPS Gene Atlas204370_atOlfactoryBulb5.9509.210Details
BioGPS Gene Atlas204370_atOvary5.1509.210Details
BioGPS Gene Atlas204370_atPancreas5.0509.210Details
BioGPS Gene Atlas204370_atPancreaticIslet7.1509.210Details
BioGPS Gene Atlas204370_atParietalLobe6.3509.210Details
BioGPS Gene Atlas204370_atPituitary7.3509.210Details
BioGPS Gene Atlas204370_atPlacenta26.6509.210Details
BioGPS Gene Atlas204370_atPons5.9509.210Details
BioGPS Gene Atlas204370_atPrefrontalCortex7.7009.210Details
BioGPS Gene Atlas204370_atProstate7.2509.210Details
BioGPS Gene Atlas204370_atSalivarygland4.9009.210Details
BioGPS Gene Atlas204370_atSkeletalMuscle7.2509.210Details
BioGPS Gene Atlas204370_atSkin4.7509.210Details
BioGPS Gene Atlas204370_atSmoothMuscle10.3009.210Details
BioGPS Gene Atlas204370_atSpinalcord6.5509.210Details
BioGPS Gene Atlas204370_atSubthalamicNucleus5.0009.210Details
BioGPS Gene Atlas204370_atSuperiorCervicalGanglion7.9009.210Details
BioGPS Gene Atlas204370_atTemporalLobe5.4009.210Details
BioGPS Gene Atlas204370_atTestis7.1009.210Details
BioGPS Gene Atlas204370_atTestisGermCell5.9509.210Details
BioGPS Gene Atlas204370_atTestisIntersitial5.6509.210Details
BioGPS Gene Atlas204370_atTestisLeydigCell8.5509.210Details
BioGPS Gene Atlas204370_atTestisSeminiferousTubule6.1509.210Details
BioGPS Gene Atlas204370_atThalamus5.7509.210Details
BioGPS Gene Atlas204370_atThymus6.4009.210Details
BioGPS Gene Atlas204370_atThyroid6.6509.210Details
BioGPS Gene Atlas204370_atTongue6.0509.210Details
BioGPS Gene Atlas204370_atTonsil9.5009.210Details
BioGPS Gene Atlas204370_atTrachea5.2509.210Details
BioGPS Gene Atlas204370_atTrigeminalGanglion8.7009.210Details
BioGPS Gene Atlas204370_atUterus6.3509.210Details
BioGPS Gene Atlas204370_atUterusCorpus7.3009.210Details
BioGPS Gene Atlas204370_atWholeBlood27.0009.210Details
BioGPS Gene Atlas204370_atWholebrain5.1009.210Details
BioGPS Gene Atlas204370_atcolon6.1509.210Details
BioGPS Gene Atlas204370_atpineal_day7.1009.210Details
BioGPS Gene Atlas204370_atpineal_night6.9609.210Details
BioGPS Gene Atlas204370_atretina7.6759.210Details
BioGPS Gene Atlas204370_atsmall_intestine5.4509.210Details
BioGPS NCI60204370_at786140.614258.980Details
BioGPS NCI60204370_atA172187.979258.980Details
BioGPS NCI60204370_atA20489.699258.980Details
BioGPS NCI60204370_atA361158.820258.980Details
BioGPS NCI60204370_atA49854.942258.980Details
BioGPS NCI60204370_atA549283.832258.980Details
BioGPS NCI60204370_atACC3129.755258.980Details
BioGPS NCI60204370_atACHN218.795258.980Details
BioGPS NCI60204370_atALVA31199.639258.980Details
BioGPS NCI60204370_atCAKI1186.926258.980Details
BioGPS NCI60204370_atCCRT CEM10.642258.980Details
BioGPS NCI60204370_atCOLO205221.350258.980Details
BioGPS NCI60204370_atDLD1223.458258.980Details
BioGPS NCI60204370_atDU145234.737258.980Details
BioGPS NCI60204370_atEKVX92.730258.980Details
BioGPS NCI60204370_atGM133189.970258.980Details
BioGPS NCI60204370_atGM1600171.427258.980Details
BioGPS NCI60204370_atGM2313214.248258.980Details
BioGPS NCI60204370_atGM2345125.705258.980Details
BioGPS NCI60204370_atGM2493277.622258.980Details
BioGPS NCI60204370_atGM97115.971258.980Details
BioGPS NCI60204370_atHCC2998360.300258.980Details
BioGPS NCI60204370_atHCT116549.735258.980Details
BioGPS NCI60204370_atHCT15370.661258.980Details
BioGPS NCI60204370_atHEK 293 T-rex135.610258.980Details
BioGPS NCI60204370_atHEK 293T402.989258.980Details
BioGPS NCI60204370_atHEK293110.197258.980Details
BioGPS NCI60204370_atHELA355.761258.980Details
BioGPS NCI60204370_atHEPG2357.504258.980Details
BioGPS NCI60204370_atHL60128.508258.980Details
BioGPS NCI60204370_atHOP62167.288258.980Details
BioGPS NCI60204370_atHOP92180.896258.980Details
BioGPS NCI60204370_atHS578T200.672258.980Details
BioGPS NCI60204370_atHSG248.429258.980Details
BioGPS NCI60204370_atHT1080709.384258.980Details
BioGPS NCI60204370_atHT29284.815258.980Details
BioGPS NCI60204370_atIGROV1143.696258.980Details
BioGPS NCI60204370_atIOSE80264.899258.980Details
BioGPS NCI60204370_atJURKAT152.179258.980Details
BioGPS NCI60204370_atK562339.384258.980Details
BioGPS NCI60204370_atKM12155.313258.980Details
BioGPS NCI60204370_atLN18431.531258.980Details
BioGPS NCI60204370_atLNCAP84.648258.980Details
BioGPS NCI60204370_atLOX IMVI499.124258.980Details
BioGPS NCI60204370_atM14204.139258.980Details
BioGPS NCI60204370_atMALME 3M74.078258.980Details
BioGPS NCI60204370_atMCF7142.231258.980Details
BioGPS NCI60204370_atMD MB231245.492258.980Details
BioGPS NCI60204370_atMDA MB435240.293258.980Details
BioGPS NCI60204370_atMOLT4250.324258.980Details
BioGPS NCI60204370_atNCI 46047.308258.980Details
BioGPS NCI60204370_atNCI H226421.637258.980Details
BioGPS NCI60204370_atNCI H2370.934258.980Details
BioGPS NCI60204370_atNCI H322M267.511258.980Details
BioGPS NCI60204370_atNCVADR RES400.484258.980Details
BioGPS NCI60204370_atOVCAR3179.776258.980Details
BioGPS NCI60204370_atOVCAR4279.032258.980Details
BioGPS NCI60204370_atOVCAR5290.631258.980Details
BioGPS NCI60204370_atOVCAR8374.271258.980Details
BioGPS NCI60204370_atPANC1130.308258.980Details
BioGPS NCI60204370_atRL7248.766258.980Details
BioGPS NCI60204370_atRPMI 8226272.193258.980Details
BioGPS NCI60204370_atRS11846332.541258.980Details
BioGPS NCI60204370_atRXF393142.231258.980Details
BioGPS NCI60204370_atSAOS235.456258.980Details
BioGPS NCI60204370_atSF268193.980258.980Details
BioGPS NCI60204370_atSF29565.797258.980Details
BioGPS NCI60204370_atSF539115.312258.980Details
BioGPS NCI60204370_atSHSYSY+RA253.220258.980Details
BioGPS NCI60204370_atSHSYSY-RA181.737258.980Details
BioGPS NCI60204370_atSKMEL258.140258.980Details
BioGPS NCI60204370_atSKMEL2846.600258.980Details
BioGPS NCI60204370_atSKMEL5182.846258.980Details
BioGPS NCI60204370_atSKOV3153.303258.980Details
BioGPS NCI60204370_atSN12C293.467258.980Details
BioGPS NCI60204370_atSNB19148.037258.980Details
BioGPS NCI60204370_atSNB7559.814258.980Details
BioGPS NCI60204370_atSR390.082258.980Details
BioGPS NCI60204370_atSW620384.969258.980Details
BioGPS NCI60204370_atT24436.317258.980Details
BioGPS NCI60204370_atT3M4141.480258.980Details
BioGPS NCI60204370_atTK10128.723258.980Details
BioGPS NCI60204370_atU118299.359258.980Details
BioGPS NCI60204370_atU138263.198258.980Details
BioGPS NCI60204370_atU20S629.987258.980Details
BioGPS NCI60204370_atU251114.149258.980Details
BioGPS NCI60204370_atU87346.546258.980Details
BioGPS NCI60204370_atUACC257120.665258.980Details
BioGPS NCI60204370_atUACC62103.276258.980Details
BioGPS NCI60204370_atUO31544.316258.980Details
BioGPS NCI60204370_atZR75_1465.897258.980Details
BioGPS NCI60204370_atastrocytes167.534258.980Details
BioGPS NCI60204370_athuh-71361.781258.980Details