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Gene ID: 1193 | CLIC2 Antibody Resource


CLIC2 Antibody Resource
Gene Full Name: 
chloride intracellular channel 2
Uniprot: 
O15247
Protein Name: 
chloride intracellular channel protein 2
Nucleotide: 
XM_005274647
Alias: 
CLIC2b;MRXS32;XAP121;
Ensembl: 
ENSG00000155962
Location: 
Xq28
HPRD: 
02139
NCBI Gene: 
1193
MIM: 
300138

Summary: 
This gene encodes a chloride intracellular channel protein. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. This protein may play a role in inhibiting the function of ryanodine receptor 2. A mutation in this gene is the cause of X-linked mental retardation-32. [provided by RefSeq, Aug 2013]
Function: 
Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.
Subcellular location: 
Cytoplasm. Membrane; Single-pass membrane protein Probable. Note: Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.
PTM: 
Disulfide bond;
Disease: 
Mental retardation, X-linked, syndromic, 32 (MRXS32) [MIM:300886]: A mental retardation syndrome characterized by profound intellectual deficit, delayed psychomotor development beginning in infancy and little or no speech development. Additional features include seizures, large joint contractures, and abnormal positioning of the thumbs. Mental retardation is defined by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP35047_T100 CLIC2 antibody - middle region (ARP35047_T100) Polyclonal Bovine, Dog, Human, Pig, Rabbit, Rat WB 100ug $229 Details
Polyclonal Antibody ARP35046_T100 CLIC2 antibody - C-terminal region (ARP35046_T100) Polyclonal Bovine, Dog, Human, Pig, Rabbit, Rat WB 100ug $229 Details
Protein OPPA00111 CLIC2 Human - Recombinant Human Chloride Intracellular Channel 2 (5ug) 5ug $100 Details

Show all CLIC2 antibodies


Product Images
CLIC2 antibody - C-terminal region (ARP35046_T100) in Human HepG2 cells using Western Blot

Sample Type: Human HepG2

CLIC2 antibody - middle region (ARP35047_T100) in Human Jurkat cells using Western Blot

Sample Type: Human Jurkat


CLIC2 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP35046 Bovine CLIC2 antibody; Bos taurus CLIC2 antibody A2VE46 93.0%
ARP35047 Bovine CLIC2 antibody; Bos taurus CLIC2 antibody A2VE46 93.0%
ARP35046 Cat CLIC2 antibody; Felis catus CLIC2 antibody M3WL94 100.0%
ARP35047 Cat CLIC2 antibody; Felis catus CLIC2 antibody M3WL94 93.0%
ARP35046 Chicken CLIC2 antibody; Gallus gallus CLIC2 antibody Q5ZKI1 86.0%
ARP35046 Chimpanzee CLIC2 antibody; Pan troglodytes CLIC2 antibody H2R4G9 100.0%
ARP35047 Chimpanzee CLIC2 antibody; Pan troglodytes CLIC2 antibody H2R4G9 100.0%
ARP35046 Collared flycatcher CLIC2 antibody; Ficedula albicollis CLIC2 antibody U3KBL4 86.0%
ARP35047 Collared flycatcher CLIC2 antibody; Ficedula albicollis CLIC2 antibody U3KBL4 79.0%
ARP35046 Dog CLIC2 antibody; Canis familiaris CLIC2 antibody J9P6I3 100.0%
ARP35047 Dog CLIC2 antibody; Canis familiaris CLIC2 antibody J9P6I3 93.0%
ARP35046 Domestic duck CLIC2 antibody; Anas platyrhynchos CLIC2 antibody U3HZG6 86.0%
ARP35046 Duckbill platypus CLIC2 antibody; Ornithorhynchus anatinus CLIC2 antibody F7C9U1 100.0%
ARP35047 Duckbill platypus CLIC2 antibody; Ornithorhynchus anatinus CLIC2 antibody F7C9U1 79.0%
ARP35046 European domestic ferret CLIC2 antibody; Mustela putorius furo CLIC2 antibody M3YXG1 100.0%
ARP35047 European domestic ferret CLIC2 antibody; Mustela putorius furo CLIC2 antibody M3YXG1 86.0%
ARP35046 Giant panda CLIC2 antibody; Ailuropoda melanoleuca CLIC2 antibody G1LR78 100.0%
ARP35046 Giant panda CLIC2 antibody; Ailuropoda melanoleuca CLIC2 antibody G1LR82 100.0%
ARP35047 Giant panda CLIC2 antibody; Ailuropoda melanoleuca CLIC2 antibody G1LR78 93.0%
ARP35047 Giant panda CLIC2 antibody; Ailuropoda melanoleuca CLIC2 antibody G1LR82 93.0%
ARP35046 Gray short-tailed opossum CLIC2 antibody; Monodelphis domestica CLIC2 antibody F7FS49 86.0%
ARP35046 Horse CLIC2 antibody; Equus caballus CLIC2 antibody F6UF33 100.0%
ARP35047 Horse CLIC2 antibody; Equus caballus CLIC2 antibody F6UF33 86.0%
ARP35047 Human CLIC2 antibody; Homo sapiens CLIC2 antibody A6PVS0 100.0%
ARP35046 Human CLIC2 antibody; Homo sapiens CLIC2 antibody O15247 100.0%
ARP35047 Human CLIC2 antibody; Homo sapiens CLIC2 antibody O15247 100.0%
ARP35047 Human CLIC2 antibody; Homo sapiens CLIC2 antibody Q86YM0 100.0%
ARP35046 Pig CLIC2 antibody; Sus scrofa CLIC2 antibody F1RZR9 100.0%
ARP35047 Pig CLIC2 antibody; Sus scrofa CLIC2 antibody F1RZR9 86.0%
ARP35046 Rabbit CLIC2 antibody; Oryctolagus cuniculus CLIC2 antibody B7NZR9 100.0%
ARP35047 Rabbit CLIC2 antibody; Oryctolagus cuniculus CLIC2 antibody B7NZR9 93.0%
ARP35046 Rainbow smelt CLIC2 antibody; Osmerus mordax CLIC2 antibody C1BIQ8 79.0%
ARP35046 Rat CLIC2 antibody; Rattus norvegicus CLIC2 antibody Q5M883 100.0%
ARP35047 Rat CLIC2 antibody; Rattus norvegicus CLIC2 antibody Q5M883 93.0%
ARP35046 Rhesus macaque CLIC2 antibody; Macaca mulatta CLIC2 antibody H9F7C4 100.0%
ARP35047 Rhesus macaque CLIC2 antibody; Macaca mulatta CLIC2 antibody H9F7C4 100.0%
ARP35047 Rhesus macaque CLIC2 antibody; Macaca mulatta CLIC2 antibody F6YUR9 100.0%
ARP35046 Rhesus macaque CLIC2 antibody; Macaca mulatta CLIC2 antibody F6YUS9 100.0%
ARP35047 Rhesus macaque CLIC2 antibody; Macaca mulatta CLIC2 antibody F6YUS9 100.0%
ARP35046 Sumatran orangutan CLIC2 antibody; Pongo abelii CLIC2 antibody H2PXC0 100.0%
ARP35047 Sumatran orangutan CLIC2 antibody; Pongo abelii CLIC2 antibody H2PXC0 100.0%
ARP35046 Tasmanian devil CLIC2 antibody; Sarcophilus harrisii CLIC2 antibody G3VH72 79.0%
ARP35046 Thirteen-lined ground squirrel CLIC2 antibody; Spermophilus tridecemlineatus CLIC2 antibody I3N2E0 100.0%
ARP35047 Thirteen-lined ground squirrel CLIC2 antibody; Spermophilus tridecemlineatus CLIC2 antibody I3N2E0 93.0%
ARP35046 White-tufted-ear marmoset CLIC2 antibody; Callithrix jacchus CLIC2 antibody B0KWV1 100.0%
ARP35047 White-tufted-ear marmoset CLIC2 antibody; Callithrix jacchus CLIC2 antibody B0KWV1 100.0%
ARP35046 White-tufted-ear marmoset CLIC2 antibody; Callithrix jacchus CLIC2 antibody F7A862 100.0%
ARP35047 White-tufted-ear marmoset CLIC2 antibody; Callithrix jacchus CLIC2 antibody F7A862 100.0%
ARP35046 White-tufted-ear marmoset CLIC2 antibody; Callithrix jacchus CLIC2 antibody U3DGX6 100.0%
ARP35047 White-tufted-ear marmoset CLIC2 antibody; Callithrix jacchus CLIC2 antibody U3DGX6 100.0%
ARP35046 Zebra finch CLIC2 antibody; Taeniopygia guttata CLIC2 antibody H0Z3C3 86.0%
ARP35047 Zebra finch CLIC2 antibody; Taeniopygia guttata CLIC2 antibody H0Z3C3 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas213415_at721_B_lymphoblasts9.70012.340Details
BioGPS Gene Atlas213415_atAdipocyte7.85012.340Details
BioGPS Gene Atlas213415_atAdrenalCortex8.45012.340Details
BioGPS Gene Atlas213415_atAdrenalgland7.00012.340Details
BioGPS Gene Atlas213415_atAmygdala7.65012.340Details
BioGPS Gene Atlas213415_atAppendix13.30012.340Details
BioGPS Gene Atlas213415_atAtrioventricularNode6.35012.340Details
BioGPS Gene Atlas213415_atBDCA4+_DentriticCells11.70012.340Details
BioGPS Gene Atlas213415_atBonemarrow9.65012.340Details
BioGPS Gene Atlas213415_atBronchialEpithelialCells7.70012.340Details
BioGPS Gene Atlas213415_atCD105+_Endothelial8.05012.340Details
BioGPS Gene Atlas213415_atCD14+_Monocytes8.65012.340Details
BioGPS Gene Atlas213415_atCD19+_BCells(neg._sel.)7.65012.340Details
BioGPS Gene Atlas213415_atCD33+_Myeloid9.75012.340Details
BioGPS Gene Atlas213415_atCD34+15.70012.340Details
BioGPS Gene Atlas213415_atCD4+_Tcells7.35012.340Details
BioGPS Gene Atlas213415_atCD56+_NKCells8.65012.340Details
BioGPS Gene Atlas213415_atCD71+_EarlyErythroid279.10012.340Details
BioGPS Gene Atlas213415_atCD8+_Tcells6.50012.340Details
BioGPS Gene Atlas213415_atCardiacMyocytes10.65012.340Details
BioGPS Gene Atlas213415_atCaudatenucleus6.95012.340Details
BioGPS Gene Atlas213415_atCerebellum6.40012.340Details
BioGPS Gene Atlas213415_atCerebellumPeduncles8.95012.340Details
BioGPS Gene Atlas213415_atCiliaryGanglion5.95012.340Details
BioGPS Gene Atlas213415_atCingulateCortex7.90012.340Details
BioGPS Gene Atlas213415_atColorectaladenocarcinoma7.65012.340Details
BioGPS Gene Atlas213415_atDorsalRootGanglion6.20012.340Details
BioGPS Gene Atlas213415_atFetalThyroid10.75012.340Details
BioGPS Gene Atlas213415_atFetalbrain7.55012.340Details
BioGPS Gene Atlas213415_atFetalliver13.15012.340Details
BioGPS Gene Atlas213415_atFetallung9.75012.340Details
BioGPS Gene Atlas213415_atGlobusPallidus5.80012.340Details
BioGPS Gene Atlas213415_atHeart11.10012.340Details
BioGPS Gene Atlas213415_atHypothalamus7.65012.340Details
BioGPS Gene Atlas213415_atKidney6.55012.340Details
BioGPS Gene Atlas213415_atLeukemia_chronicMyelogenousK-56249.20012.340Details
BioGPS Gene Atlas213415_atLeukemia_promyelocytic-HL-606.65012.340Details
BioGPS Gene Atlas213415_atLeukemialymphoblastic(MOLT-4)5.80012.340Details
BioGPS Gene Atlas213415_atLiver11.30012.340Details
BioGPS Gene Atlas213415_atLung8.70012.340Details
BioGPS Gene Atlas213415_atLymphnode14.30012.340Details
BioGPS Gene Atlas213415_atLymphoma_burkitts(Daudi)10.15012.340Details
BioGPS Gene Atlas213415_atLymphoma_burkitts(Raji)11.30012.340Details
BioGPS Gene Atlas213415_atMedullaOblongata6.85012.340Details
BioGPS Gene Atlas213415_atOccipitalLobe6.70012.340Details
BioGPS Gene Atlas213415_atOlfactoryBulb6.10012.340Details
BioGPS Gene Atlas213415_atOvary5.70012.340Details
BioGPS Gene Atlas213415_atPancreas6.35012.340Details
BioGPS Gene Atlas213415_atPancreaticIslet10.90012.340Details
BioGPS Gene Atlas213415_atParietalLobe8.40012.340Details
BioGPS Gene Atlas213415_atPituitary9.20012.340Details
BioGPS Gene Atlas213415_atPlacenta7.85012.340Details
BioGPS Gene Atlas213415_atPons7.85012.340Details
BioGPS Gene Atlas213415_atPrefrontalCortex9.25012.340Details
BioGPS Gene Atlas213415_atProstate8.90012.340Details
BioGPS Gene Atlas213415_atSalivarygland6.90012.340Details
BioGPS Gene Atlas213415_atSkeletalMuscle11.15012.340Details
BioGPS Gene Atlas213415_atSkin6.40012.340Details
BioGPS Gene Atlas213415_atSmoothMuscle8.85012.340Details
BioGPS Gene Atlas213415_atSpinalcord8.10012.340Details
BioGPS Gene Atlas213415_atSubthalamicNucleus7.15012.340Details
BioGPS Gene Atlas213415_atSuperiorCervicalGanglion9.65012.340Details
BioGPS Gene Atlas213415_atTemporalLobe7.25012.340Details
BioGPS Gene Atlas213415_atTestis6.55012.340Details
BioGPS Gene Atlas213415_atTestisGermCell6.20012.340Details
BioGPS Gene Atlas213415_atTestisIntersitial6.55012.340Details
BioGPS Gene Atlas213415_atTestisLeydigCell7.80012.340Details
BioGPS Gene Atlas213415_atTestisSeminiferousTubule6.70012.340Details
BioGPS Gene Atlas213415_atThalamus7.90012.340Details
BioGPS Gene Atlas213415_atThymus5.90012.340Details
BioGPS Gene Atlas213415_atThyroid33.15012.340Details
BioGPS Gene Atlas213415_atTongue11.15012.340Details
BioGPS Gene Atlas213415_atTonsil9.90012.340Details
BioGPS Gene Atlas213415_atTrachea6.60012.340Details
BioGPS Gene Atlas213415_atTrigeminalGanglion10.50012.340Details
BioGPS Gene Atlas213415_atUterus10.90012.340Details
BioGPS Gene Atlas213415_atUterusCorpus8.25012.340Details
BioGPS Gene Atlas213415_atWholeBlood8.05012.340Details
BioGPS Gene Atlas213415_atWholebrain6.50012.340Details
BioGPS Gene Atlas213415_atcolon8.05012.340Details
BioGPS Gene Atlas213415_atpineal_day9.78012.340Details
BioGPS Gene Atlas213415_atpineal_night9.30012.340Details
BioGPS Gene Atlas213415_atretina9.30012.340Details
BioGPS Gene Atlas213415_atsmall_intestine8.25012.340Details
BioGPS NCI60213415_at7865.72025.490Details
BioGPS NCI60213415_atA17237.03325.490Details
BioGPS NCI60213415_atA2045.52125.490Details
BioGPS NCI60213415_atA3615.59825.490Details
BioGPS NCI60213415_atA4985.42225.490Details
BioGPS NCI60213415_atA5495.63625.490Details
BioGPS NCI60213415_atACC35.93625.490Details
BioGPS NCI60213415_atACHN4.98925.490Details
BioGPS NCI60213415_atALVA316.31425.490Details
BioGPS NCI60213415_atCAKI15.84825.490Details
BioGPS NCI60213415_atCCRT CEM7.47225.490Details
BioGPS NCI60213415_atCOLO2055.53225.490Details
BioGPS NCI60213415_atDLD15.29925.490Details
BioGPS NCI60213415_atDU1455.12125.490Details
BioGPS NCI60213415_atEKVX5.15825.490Details
BioGPS NCI60213415_atGM133201.14525.490Details
BioGPS NCI60213415_atGM16005.89025.490Details
BioGPS NCI60213415_atGM231310.04725.490Details
BioGPS NCI60213415_atGM23455.58125.490Details
BioGPS NCI60213415_atGM24937.57425.490Details
BioGPS NCI60213415_atGM976.54025.490Details
BioGPS NCI60213415_atHCC29984.73625.490Details
BioGPS NCI60213415_atHCT1165.48225.490Details
BioGPS NCI60213415_atHCT154.98825.490Details
BioGPS NCI60213415_atHEK 293 T-rex5.77925.490Details
BioGPS NCI60213415_atHEK 293T5.45525.490Details
BioGPS NCI60213415_atHEK2935.42825.490Details
BioGPS NCI60213415_atHELA4.98525.490Details
BioGPS NCI60213415_atHEPG25.53225.490Details
BioGPS NCI60213415_atHL605.98325.490Details
BioGPS NCI60213415_atHOP62187.24025.490Details
BioGPS NCI60213415_atHOP925.18525.490Details
BioGPS NCI60213415_atHS578T5.44525.490Details
BioGPS NCI60213415_atHSG5.14525.490Details
BioGPS NCI60213415_atHT10805.30625.490Details
BioGPS NCI60213415_atHT296.10325.490Details
BioGPS NCI60213415_atIGROV15.34925.490Details
BioGPS NCI60213415_atIOSE805.48725.490Details
BioGPS NCI60213415_atJURKAT5.45625.490Details
BioGPS NCI60213415_atK562435.00225.490Details
BioGPS NCI60213415_atKM125.84325.490Details
BioGPS NCI60213415_atLN185.30425.490Details
BioGPS NCI60213415_atLNCAP5.53625.490Details
BioGPS NCI60213415_atLOX IMVI5.46025.490Details
BioGPS NCI60213415_atM145.42825.490Details
BioGPS NCI60213415_atMALME 3M6.00925.490Details
BioGPS NCI60213415_atMCF75.20425.490Details
BioGPS NCI60213415_atMD MB2315.58725.490Details
BioGPS NCI60213415_atMDA MB4356.16225.490Details
BioGPS NCI60213415_atMOLT45.80725.490Details
BioGPS NCI60213415_atNCI 4605.67125.490Details
BioGPS NCI60213415_atNCI H2265.80225.490Details
BioGPS NCI60213415_atNCI H235.45025.490Details
BioGPS NCI60213415_atNCI H322M5.41725.490Details
BioGPS NCI60213415_atNCVADR RES50.55525.490Details
BioGPS NCI60213415_atOVCAR35.87225.490Details
BioGPS NCI60213415_atOVCAR45.44025.490Details
BioGPS NCI60213415_atOVCAR55.27925.490Details
BioGPS NCI60213415_atOVCAR839.89525.490Details
BioGPS NCI60213415_atPANC15.65225.490Details
BioGPS NCI60213415_atRL75.65225.490Details
BioGPS NCI60213415_atRPMI 8226512.46925.490Details
BioGPS NCI60213415_atRS118465.94225.490Details
BioGPS NCI60213415_atRXF3935.53425.490Details
BioGPS NCI60213415_atSAOS25.60225.490Details
BioGPS NCI60213415_atSF2685.42425.490Details
BioGPS NCI60213415_atSF2955.23025.490Details
BioGPS NCI60213415_atSF5395.20925.490Details
BioGPS NCI60213415_atSHSYSY+RA5.12225.490Details
BioGPS NCI60213415_atSHSYSY-RA5.45125.490Details
BioGPS NCI60213415_atSKMEL25.47025.490Details
BioGPS NCI60213415_atSKMEL285.58525.490Details
BioGPS NCI60213415_atSKMEL55.07525.490Details
BioGPS NCI60213415_atSKOV35.79425.490Details
BioGPS NCI60213415_atSN12C5.41125.490Details
BioGPS NCI60213415_atSNB194.98125.490Details
BioGPS NCI60213415_atSNB755.34925.490Details
BioGPS NCI60213415_atSR5.70825.490Details
BioGPS NCI60213415_atSW6205.63725.490Details
BioGPS NCI60213415_atT245.65725.490Details
BioGPS NCI60213415_atT3M45.82225.490Details
BioGPS NCI60213415_atTK105.38525.490Details
BioGPS NCI60213415_atU11813.34125.490Details
BioGPS NCI60213415_atU138341.98825.490Details
BioGPS NCI60213415_atU20S6.17225.490Details
BioGPS NCI60213415_atU2515.32725.490Details
BioGPS NCI60213415_atU875.59625.490Details
BioGPS NCI60213415_atUACC2575.27825.490Details
BioGPS NCI60213415_atUACC625.61225.490Details
BioGPS NCI60213415_atUO315.18825.490Details
BioGPS NCI60213415_atZR75_15.74725.490Details
BioGPS NCI60213415_atastrocytes5.56625.490Details
BioGPS NCI60213415_athuh-76.23825.490Details