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Gene ID: 26253 | CLEC4E Antibody Resource


CLEC4E Antibody Resource
Gene Full Name: 
C-type lectin domain family 4, member E
Uniprot: 
Q9ULY5
Protein Name: 
C-type lectin domain family 4 member E
Nucleotide: 
NM_014358
Alias: 
MINCLE;CLECSF9;
Ensembl: 
ENSG00000166523
Location: 
12p13.31
HPRD: 
13075
NCBI Gene: 
26253
MIM: 
609962

Summary: 
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]
Function: 
C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
Subcellular location: 
Membrane; Single-pass type II membrane protein Probable.
PTM: 
Disulfide bond;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Monoclonal Antibody OAPA00364 CLEC4E Antibody (OAPA00364) Monoclonal Human ELISA, IF, WB 5ug $100 Details
Polyclonal Antibody ARP47015_P050 CLEC4E Antibody (ARP47015_P050) Polyclonal Bovine, Human Not tested 50 ug $125 Details

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Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP47015 Bovine CLEC4E antibody; Bos taurus CLEC4E antibody E1BHM0 83.0%
ARP47015 Cat CLEC4E antibody; Felis catus CLEC4E antibody M3WHV1 85.0%
ARP47015 Chimpanzee CLEC4E antibody; Pan troglodytes CLEC4E antibody H2Q5D5 100.0%
ARP47015 Guinea pig CLEC4E antibody; Cavia porcellus CLEC4E antibody H0VD62 82.0%
ARP47015 Human CLEC4E antibody; Homo sapiens CLEC4E antibody F5H5X7 100.0%
ARP47015 Human CLEC4E antibody; Homo sapiens CLEC4E antibody Q9ULY5 100.0%
ARP47015 Rhesus macaque CLEC4E antibody; Macaca mulatta CLEC4E antibody F6S592 93.0%
ARP47015 Sumatran orangutan CLEC4E antibody; Pongo abelii CLEC4E antibody H2NGE6 100.0%
ARP47015 White-tufted-ear marmoset CLEC4E antibody; Callithrix jacchus CLEC4E antibody F7I1U1 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas219859_at721_B_lymphoblasts7.1507.410Details
BioGPS Gene Atlas219859_atAdipocyte5.9007.410Details
BioGPS Gene Atlas219859_atAdrenalCortex6.9507.410Details
BioGPS Gene Atlas219859_atAdrenalgland5.0507.410Details
BioGPS Gene Atlas219859_atAmygdala6.2507.410Details
BioGPS Gene Atlas219859_atAppendix32.9507.410Details
BioGPS Gene Atlas219859_atAtrioventricularNode5.9007.410Details
BioGPS Gene Atlas219859_atBDCA4+_DentriticCells6.2507.410Details
BioGPS Gene Atlas219859_atBonemarrow5.8007.410Details
BioGPS Gene Atlas219859_atBronchialEpithelialCells5.7507.410Details
BioGPS Gene Atlas219859_atCD105+_Endothelial5.9507.410Details
BioGPS Gene Atlas219859_atCD14+_Monocytes7.1507.410Details
BioGPS Gene Atlas219859_atCD19+_BCells(neg._sel.)6.4007.410Details
BioGPS Gene Atlas219859_atCD33+_Myeloid7.7507.410Details
BioGPS Gene Atlas219859_atCD34+7.6507.410Details
BioGPS Gene Atlas219859_atCD4+_Tcells6.6007.410Details
BioGPS Gene Atlas219859_atCD56+_NKCells7.2507.410Details
BioGPS Gene Atlas219859_atCD71+_EarlyErythroid5.7007.410Details
BioGPS Gene Atlas219859_atCD8+_Tcells5.8507.410Details
BioGPS Gene Atlas219859_atCardiacMyocytes7.5507.410Details
BioGPS Gene Atlas219859_atCaudatenucleus5.3007.410Details
BioGPS Gene Atlas219859_atCerebellum4.8007.410Details
BioGPS Gene Atlas219859_atCerebellumPeduncles6.7507.410Details
BioGPS Gene Atlas219859_atCiliaryGanglion7.9007.410Details
BioGPS Gene Atlas219859_atCingulateCortex6.3007.410Details
BioGPS Gene Atlas219859_atColorectaladenocarcinoma6.0007.410Details
BioGPS Gene Atlas219859_atDorsalRootGanglion16.8007.410Details
BioGPS Gene Atlas219859_atFetalThyroid5.8507.410Details
BioGPS Gene Atlas219859_atFetalbrain5.9507.410Details
BioGPS Gene Atlas219859_atFetalliver5.1507.410Details
BioGPS Gene Atlas219859_atFetallung5.0007.410Details
BioGPS Gene Atlas219859_atGlobusPallidus4.8007.410Details
BioGPS Gene Atlas219859_atHeart7.6007.410Details
BioGPS Gene Atlas219859_atHypothalamus6.5007.410Details
BioGPS Gene Atlas219859_atKidney4.7507.410Details
BioGPS Gene Atlas219859_atLeukemia_chronicMyelogenousK-5625.3507.410Details
BioGPS Gene Atlas219859_atLeukemia_promyelocytic-HL-605.2007.410Details
BioGPS Gene Atlas219859_atLeukemialymphoblastic(MOLT-4)4.5507.410Details
BioGPS Gene Atlas219859_atLiver8.8507.410Details
BioGPS Gene Atlas219859_atLung6.6007.410Details
BioGPS Gene Atlas219859_atLymphnode5.0507.410Details
BioGPS Gene Atlas219859_atLymphoma_burkitts(Daudi)7.5007.410Details
BioGPS Gene Atlas219859_atLymphoma_burkitts(Raji)8.3507.410Details
BioGPS Gene Atlas219859_atMedullaOblongata5.4507.410Details
BioGPS Gene Atlas219859_atOccipitalLobe5.3007.410Details
BioGPS Gene Atlas219859_atOlfactoryBulb4.7007.410Details
BioGPS Gene Atlas219859_atOvary6.7507.410Details
BioGPS Gene Atlas219859_atPancreas4.8507.410Details
BioGPS Gene Atlas219859_atPancreaticIslet6.3507.410Details
BioGPS Gene Atlas219859_atParietalLobe6.3507.410Details
BioGPS Gene Atlas219859_atPituitary6.9507.410Details
BioGPS Gene Atlas219859_atPlacenta6.0507.410Details
BioGPS Gene Atlas219859_atPons5.9007.410Details
BioGPS Gene Atlas219859_atPrefrontalCortex7.3007.410Details
BioGPS Gene Atlas219859_atProstate7.0507.410Details
BioGPS Gene Atlas219859_atSalivarygland5.3507.410Details
BioGPS Gene Atlas219859_atSkeletalMuscle8.1507.410Details
BioGPS Gene Atlas219859_atSkin7.1507.410Details
BioGPS Gene Atlas219859_atSmoothMuscle6.7507.410Details
BioGPS Gene Atlas219859_atSpinalcord6.3507.410Details
BioGPS Gene Atlas219859_atSubthalamicNucleus5.5007.410Details
BioGPS Gene Atlas219859_atSuperiorCervicalGanglion49.7007.410Details
BioGPS Gene Atlas219859_atTemporalLobe5.6507.410Details
BioGPS Gene Atlas219859_atTestis5.3007.410Details
BioGPS Gene Atlas219859_atTestisGermCell5.1007.410Details
BioGPS Gene Atlas219859_atTestisIntersitial5.2507.410Details
BioGPS Gene Atlas219859_atTestisLeydigCell6.9007.410Details
BioGPS Gene Atlas219859_atTestisSeminiferousTubule5.1507.410Details
BioGPS Gene Atlas219859_atThalamus6.0507.410Details
BioGPS Gene Atlas219859_atThymus4.7507.410Details
BioGPS Gene Atlas219859_atThyroid7.4007.410Details
BioGPS Gene Atlas219859_atTongue9.0507.410Details
BioGPS Gene Atlas219859_atTonsil5.8507.410Details
BioGPS Gene Atlas219859_atTrachea4.9507.410Details
BioGPS Gene Atlas219859_atTrigeminalGanglion19.6007.410Details
BioGPS Gene Atlas219859_atUterus4.9007.410Details
BioGPS Gene Atlas219859_atUterusCorpus5.6507.410Details
BioGPS Gene Atlas219859_atWholeBlood14.0507.410Details
BioGPS Gene Atlas219859_atWholebrain5.1507.410Details
BioGPS Gene Atlas219859_atcolon6.0007.410Details
BioGPS Gene Atlas219859_atpineal_day7.3007.410Details
BioGPS Gene Atlas219859_atpineal_night7.0807.410Details
BioGPS Gene Atlas219859_atretina7.4507.410Details
BioGPS Gene Atlas219859_atsmall_intestine5.8007.410Details
BioGPS NCI60219859_at7864.8694.690Details
BioGPS NCI60219859_atA1724.4674.690Details
BioGPS NCI60219859_atA2044.5494.690Details
BioGPS NCI60219859_atA3614.6274.690Details
BioGPS NCI60219859_atA4984.5804.690Details
BioGPS NCI60219859_atA5494.6664.690Details
BioGPS NCI60219859_atACC34.7854.690Details
BioGPS NCI60219859_atACHN4.4054.690Details
BioGPS NCI60219859_atALVA315.2894.690Details
BioGPS NCI60219859_atCAKI14.7084.690Details
BioGPS NCI60219859_atCCRT CEM6.0994.690Details
BioGPS NCI60219859_atCOLO2054.5714.690Details
BioGPS NCI60219859_atDLD14.4934.690Details
BioGPS NCI60219859_atDU1454.2964.690Details
BioGPS NCI60219859_atEKVX4.4764.690Details
BioGPS NCI60219859_atGM1334.8174.690Details
BioGPS NCI60219859_atGM16005.1004.690Details
BioGPS NCI60219859_atGM23134.8284.690Details
BioGPS NCI60219859_atGM23454.6094.690Details
BioGPS NCI60219859_atGM24935.1574.690Details
BioGPS NCI60219859_atGM975.9744.690Details
BioGPS NCI60219859_atHCC29984.3334.690Details
BioGPS NCI60219859_atHCT1164.5664.690Details
BioGPS NCI60219859_atHCT154.2244.690Details
BioGPS NCI60219859_atHEK 293 T-rex4.9604.690Details
BioGPS NCI60219859_atHEK 293T4.6144.690Details
BioGPS NCI60219859_atHEK2934.6974.690Details
BioGPS NCI60219859_atHELA4.2614.690Details
BioGPS NCI60219859_atHEPG24.5924.690Details
BioGPS NCI60219859_atHL604.8704.690Details
BioGPS NCI60219859_atHOP624.6144.690Details
BioGPS NCI60219859_atHOP924.4874.690Details
BioGPS NCI60219859_atHS578T4.5634.690Details
BioGPS NCI60219859_atHSG4.4594.690Details
BioGPS NCI60219859_atHT10804.4924.690Details
BioGPS NCI60219859_atHT294.9334.690Details
BioGPS NCI60219859_atIGROV14.5354.690Details
BioGPS NCI60219859_atIOSE804.5754.690Details
BioGPS NCI60219859_atJURKAT4.5904.690Details
BioGPS NCI60219859_atK5624.7884.690Details
BioGPS NCI60219859_atKM124.7204.690Details
BioGPS NCI60219859_atLN184.4784.690Details
BioGPS NCI60219859_atLNCAP4.5804.690Details
BioGPS NCI60219859_atLOX IMVI4.5824.690Details
BioGPS NCI60219859_atM144.5804.690Details
BioGPS NCI60219859_atMALME 3M4.7794.690Details
BioGPS NCI60219859_atMCF74.4964.690Details
BioGPS NCI60219859_atMD MB2314.6234.690Details
BioGPS NCI60219859_atMDA MB4354.7734.690Details
BioGPS NCI60219859_atMOLT44.9784.690Details
BioGPS NCI60219859_atNCI 4604.6854.690Details
BioGPS NCI60219859_atNCI H2264.6754.690Details
BioGPS NCI60219859_atNCI H234.5944.690Details
BioGPS NCI60219859_atNCI H322M4.5754.690Details
BioGPS NCI60219859_atNCVADR RES4.4854.690Details
BioGPS NCI60219859_atOVCAR34.7444.690Details
BioGPS NCI60219859_atOVCAR44.5554.690Details
BioGPS NCI60219859_atOVCAR54.5344.690Details
BioGPS NCI60219859_atOVCAR84.4344.690Details
BioGPS NCI60219859_atPANC14.6484.690Details
BioGPS NCI60219859_atRL74.6604.690Details
BioGPS NCI60219859_atRPMI 82264.6444.690Details
BioGPS NCI60219859_atRS118464.7394.690Details
BioGPS NCI60219859_atRXF3934.5934.690Details
BioGPS NCI60219859_atSAOS24.6294.690Details
BioGPS NCI60219859_atSF2684.5804.690Details
BioGPS NCI60219859_atSF2954.5344.690Details
BioGPS NCI60219859_atSF5394.4044.690Details
BioGPS NCI60219859_atSHSYSY+RA4.3174.690Details
BioGPS NCI60219859_atSHSYSY-RA4.4844.690Details
BioGPS NCI60219859_atSKMEL24.5964.690Details
BioGPS NCI60219859_atSKMEL284.6084.690Details
BioGPS NCI60219859_atSKMEL54.3054.690Details
BioGPS NCI60219859_atSKOV34.7214.690Details
BioGPS NCI60219859_atSN12C4.5884.690Details
BioGPS NCI60219859_atSNB194.4544.690Details
BioGPS NCI60219859_atSNB754.5064.690Details
BioGPS NCI60219859_atSR4.6674.690Details
BioGPS NCI60219859_atSW6204.5984.690Details
BioGPS NCI60219859_atT244.6464.690Details
BioGPS NCI60219859_atT3M44.7444.690Details
BioGPS NCI60219859_atTK104.5444.690Details
BioGPS NCI60219859_atU1184.5584.690Details
BioGPS NCI60219859_atU1384.4514.690Details
BioGPS NCI60219859_atU20S4.5354.690Details
BioGPS NCI60219859_atU2514.4854.690Details
BioGPS NCI60219859_atU874.5254.690Details
BioGPS NCI60219859_atUACC2574.3914.690Details
BioGPS NCI60219859_atUACC624.6394.690Details
BioGPS NCI60219859_atUO319.5064.690Details
BioGPS NCI60219859_atZR75_14.6654.690Details
BioGPS NCI60219859_atastrocytes4.6494.690Details
BioGPS NCI60219859_athuh-74.9074.690Details