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Gene ID: 149461 | CLDN19 Antibody Resource


CLDN19 Antibody Resource
Gene Full Name: 
claudin 19
Uniprot: 
Q8N6F1
Protein Name: 
claudin-19
Nucleotide: 
NM_001185117
Alias: 
HOMG5;
Ensembl: 
ENSG00000164007
Location: 
1p34.2
HPRD: 
10834
NCBI Gene: 
149461
MIM: 
610036

Summary: 
The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010]
Function: 
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity .
Subcellular location: 
Cell junction › tight junction. Cell membrane; Multi-pass membrane protein.
PTM: 
Disease: 
Hypomagnesemia 5 (HOMG5) [MIM:248190]: A progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. The renal phenotype is virtually undistinguishable from that of patients with HOMG3. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP33619_P050 CLDN19 antibody - C-terminal region (ARP33619_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Mouse, Pig, Rabbit WB 50ug $289 Details
Polyclonal Antibody ARP33620_P050 CLDN19 Antibody (ARP33620_P050) Polyclonal Dog, Guinea pig, Human, Mouse, Pig, Rabbit Not tested 50 ug $50 Details
Polyclonal Antibody OAAF03502 CLDN19 Antibody (OAAF03502) Polyclonal Human WB, ELISA 100 ug $289 Details

Show all CLDN19 antibodies


Product Images
CLDN19 antibody - C-terminal region (ARP33619_P050) in Transfected 293T cells using Western Blot

Sample Type: Transfected 293T

CLDN19 Antibody (OAAF03502) in HepG2, Jurkat cells using Western Blot

Sample Type: HepG2, Jurkat


CLDN19 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP33619 Bovine CLDN19 antibody; Bos taurus CLDN19 antibody A7MBD3 86.0%
ARP33619 Cat CLDN19 antibody; Felis catus CLDN19 antibody M3WGH6 100.0%
ARP33620 Chimpanzee CLDN19 antibody; Pan troglodytes CLDN19 antibody H2PYT7 100.0%
ARP33619 Dog CLDN19 antibody; Canis familiaris CLDN19 antibody E2R1A2 100.0%
ARP33620 Dog CLDN19 antibody; Canis familiaris CLDN19 antibody E2R1A2 92.0%
ARP33619 European domestic ferret CLDN19 antibody; Mustela putorius furo CLDN19 antibody M3YR56 100.0%
ARP33620 European domestic ferret CLDN19 antibody; Mustela putorius furo CLDN19 antibody M3YR56 92.0%
ARP33619 Giant panda CLDN19 antibody; Ailuropoda melanoleuca CLDN19 antibody G1L607 100.0%
ARP33620 Giant panda CLDN19 antibody; Ailuropoda melanoleuca CLDN19 antibody G1L607 85.0%
ARP33619 Horse CLDN19 antibody; Equus caballus CLDN19 antibody F6RGA7 93.0%
ARP33619 Human CLDN19 antibody; Homo sapiens CLDN19 antibody Q8N6F1-2 100.0%
ARP33619 Human CLDN19 antibody; Homo sapiens CLDN19 antibody Q8N6F1 100.0%
ARP33620 Human CLDN19 antibody; Homo sapiens CLDN19 antibody Q8N6F1 100.0%
ARP33619 Little brown bat CLDN19 antibody; Myotis lucifugus CLDN19 antibody G1PN70 93.0%
ARP33620 Mouse CLDN19 antibody; Mus musculus CLDN19 antibody Q9ET38 92.0%
ARP33619 Mouse CLDN19 antibody; Mus musculus CLDN19 antibody Q9ET38-2 79.0%
ARP33619 Mouse CLDN19 antibody; Mus musculus CLDN19 antibody Q9ET38 79.0%
ARP33619 Mouse CLDN19 antibody; Mus musculus CLDN19 antibody Q3UNX6 79.0%
ARP33619 Pig CLDN19 antibody; Sus scrofa CLDN19 antibody C3VMW5 100.0%
ARP33620 Pig CLDN19 antibody; Sus scrofa CLDN19 antibody C3VMW5 85.0%
ARP33619 Rabbit CLDN19 antibody; Oryctolagus cuniculus CLDN19 antibody G1U697 100.0%
ARP33620 Rabbit CLDN19 antibody; Oryctolagus cuniculus CLDN19 antibody G1U697 100.0%
ARP33619 Rat CLDN19 antibody; Rattus norvegicus CLDN19 antibody Q5QT56-2 79.0%
ARP33619 Rat CLDN19 antibody; Rattus norvegicus CLDN19 antibody Q5QT56 79.0%
ARP33619 Rhesus macaque CLDN19 antibody; Macaca mulatta CLDN19 antibody F6YYW5 100.0%
ARP33620 Rhesus macaque CLDN19 antibody; Macaca mulatta CLDN19 antibody F6YYW5 100.0%
ARP33620 Small-eared galago CLDN19 antibody; Otolemur garnettii CLDN19 antibody H0XHE2 100.0%
ARP33619 Small-eared galago CLDN19 antibody; Otolemur garnettii CLDN19 antibody H0XHE2 93.0%
ARP33619 Thirteen-lined ground squirrel CLDN19 antibody; Spermophilus tridecemlineatus CLDN19 antibody I3LW02 93.0%
ARP33620 Thirteen-lined ground squirrel CLDN19 antibody; Spermophilus tridecemlineatus CLDN19 antibody I3LW02 92.0%
ARP33620 White-tufted-ear marmoset CLDN19 antibody; Callithrix jacchus CLDN19 antibody F7HRA4 100.0%
ARP33619 White-tufted-ear marmoset CLDN19 antibody; Callithrix jacchus CLDN19 antibody F7HRA4 93.0%

Tissue & Cell Line Gene Expression Data