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Gene ID: 1187 | CLCNKA Antibody Resource


CLCNKA Antibody Resource
Gene Full Name: 
chloride channel, voltage-sensitive Ka
Uniprot: 
P51800
Protein Name: 
chloride channel protein ClC-Ka
Nucleotide: 
NM_004070
Alias: 
CLCK1;ClC-K1;hClC-Ka;
Ensembl: 
ENSG00000186510
Location: 
1p36
HPRD: 
03608
NCBI Gene: 
1187
MIM: 
602024

Summary: 
This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function: 
Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms.
Subcellular location: 
Membrane; Multi-pass membrane protein.
PTM: 
Disease: 
Bartter syndrome 4B (BS4B) [MIM:613090]: A digenic, recessive disorder characterized by impaired salt reabsorption in the thick ascending loop of Henle with pronounced salt wasting, hypokalemic metabolic alkalosis, and varying degrees of hypercalciuria. Bartter syndrome type 4B is associated with sensorineural deafness. Note: The disease is caused by mutations affecting distinct genetic loci, including the gene represented in this entry. Loss-of-function of both CLCNKA and CLCNKB results in the disease phenotype ().
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP35132_P050 CLCNKA antibody - N-terminal region (ARP35132_P050) Polyclonal Human WB 50ug $289 Details
Polyclonal Antibody ARP37680_P050 CLCNKA Antibody (ARP37680_P050) Polyclonal Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP41454_P050 CLCNKA Antibody (ARP41454_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP41543_P050 CLCNKA Antibody (ARP41543_P050) Polyclonal Dog, Human, Mouse, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB12858 CLCNKA antibody - N - terminal region (OAAB12858) Human WB 400ul $289 Details
Polyclonal Antibody OAAF03485 CLCNKA Antibody (OAAF03485) Polyclonal Human WB, ELISA 100 ug $289 Details

Show all CLCNKA antibodies


Product Images
CLCNKA antibody - N-terminal region (ARP35132_P050) in Human Liver cells using Western Blot

Sample Type: Human Liver

CLCNKA antibody - N - terminal region (OAAB12858) in NCI-H460 cells using Western Blot

Sample Type: NCI-H460

CLCNKA Antibody (OAAF03485) in HuvEc cells using Western Blot

Sample Type: HuvEc


CLCNKA Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP41454 Chimpanzee CLCNKA antibody; Pan troglodytes CLCNKA antibody H2PY44 100.0%
ARP34916 Chimpanzee CLCNKA antibody; Pan troglodytes CLCNKA antibody H2PY44 93.0%
ARP37680 Chimpanzee CLCNKA antibody; Pan troglodytes CLCNKA antibody H2PY44 93.0%
ARP35132 Chimpanzee CLCNKA antibody; Pan troglodytes CLCNKA antibody H2PY44 92.0%
ARP41543 Chimpanzee CLCNKA antibody; Pan troglodytes CLCNKA antibody H2PY44 86.0%
ARP37680 Human CLCNKA antibody; Homo sapiens CLCNKA antibody P51800-2 100.0%
ARP41543 Human CLCNKA antibody; Homo sapiens CLCNKA antibody P51800-2 100.0%
ARP35132 Human CLCNKA antibody; Homo sapiens CLCNKA antibody P51800-3 100.0%
ARP37680 Human CLCNKA antibody; Homo sapiens CLCNKA antibody P51800-3 100.0%
ARP41454 Human CLCNKA antibody; Homo sapiens CLCNKA antibody P51800-3 100.0%
ARP41543 Human CLCNKA antibody; Homo sapiens CLCNKA antibody P51800-3 100.0%
ARP35132 Human CLCNKA antibody; Homo sapiens CLCNKA antibody P51800 100.0%
ARP37680 Human CLCNKA antibody; Homo sapiens CLCNKA antibody P51800 100.0%
ARP41454 Human CLCNKA antibody; Homo sapiens CLCNKA antibody P51800 100.0%
ARP41543 Human CLCNKA antibody; Homo sapiens CLCNKA antibody P51800 100.0%
ARP35132 Human CLCNKA antibody; Homo sapiens CLCNKA antibody P51800-2 100.0%
ARP34916 Human CLCNKA antibody; Homo sapiens CLCNKA antibody P51800-3 86.0%
ARP34916 Human CLCNKA antibody; Homo sapiens CLCNKA antibody P51800 86.0%
ARP34916 Human CLCNKA antibody; Homo sapiens CLCNKA antibody P51800-2 86.0%
ARP34916 Mouse CLCNKA antibody; Mus musculus CLCNKA antibody Q9WUB7 93.0%
ARP41454 Mouse CLCNKA antibody; Mus musculus CLCNKA antibody Q9WUB7 93.0%
ARP34916 Mouse CLCNKA antibody; Mus musculus CLCNKA antibody A2ADB4 93.0%
ARP41454 Mouse CLCNKA antibody; Mus musculus CLCNKA antibody A2ADB4 93.0%
ARP34917 Mouse CLCNKA antibody; Mus musculus CLCNKA antibody Q9WUB7 86.0%
ARP37680 Mouse CLCNKA antibody; Mus musculus CLCNKA antibody Q9WUB7 86.0%
ARP37680 Mouse CLCNKA antibody; Mus musculus CLCNKA antibody A2ADB4 86.0%
ARP35132 Mouse CLCNKA antibody; Mus musculus CLCNKA antibody Q9WUB7 85.0%
ARP35132 Mouse CLCNKA antibody; Mus musculus CLCNKA antibody A2ADB4 85.0%
ARP41543 Mouse CLCNKA antibody; Mus musculus CLCNKA antibody Q9WUB7 79.0%
ARP34916 Pig CLCNKA antibody; Sus scrofa CLCNKA antibody I3L7A1 93.0%
ARP41454 Pig CLCNKA antibody; Sus scrofa CLCNKA antibody I3L7A1 93.0%
ARP37680 Pig CLCNKA antibody; Sus scrofa CLCNKA antibody I3L7A1 86.0%
ARP35132 Pig CLCNKA antibody; Sus scrofa CLCNKA antibody I3L7A1 85.0%
ARP34916 Rabbit CLCNKA antibody; Oryctolagus cuniculus CLCNKA antibody P51803 93.0%
ARP34917 Rabbit CLCNKA antibody; Oryctolagus cuniculus CLCNKA antibody P51803 93.0%
ARP41454 Rabbit CLCNKA antibody; Oryctolagus cuniculus CLCNKA antibody P51803 93.0%
ARP37680 Rabbit CLCNKA antibody; Oryctolagus cuniculus CLCNKA antibody P51803 79.0%
ARP34916 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody F1LRC4 93.0%
ARP34916 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody Q06393 93.0%
ARP34916 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody Q66HN9 93.0%
ARP37680 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody F1LRC4 86.0%
ARP41454 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody F1LRC4 86.0%
ARP41543 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody F1LRC4 86.0%
ARP34917 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody Q06393 86.0%
ARP37680 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody Q06393 86.0%
ARP41454 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody Q06393 86.0%
ARP41543 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody Q06393 86.0%
ARP34917 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody Q66HN9 86.0%
ARP37680 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody Q66HN9 86.0%
ARP41454 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody Q66HN9 86.0%
ARP41543 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody Q66HN9 86.0%
ARP35132 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody F1LRC4 85.0%
ARP35132 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody Q06393 85.0%
ARP35132 Rat CLCNKA antibody; Rattus norvegicus CLCNKA antibody Q66HN9 85.0%
ARP41454 Rhesus macaque CLCNKA antibody; Macaca mulatta CLCNKA antibody F7E038 100.0%
ARP41543 Rhesus macaque CLCNKA antibody; Macaca mulatta CLCNKA antibody F7E038 93.0%
ARP41543 Sumatran orangutan CLCNKA antibody; Pongo abelii CLCNKA antibody H2N8Y2 93.0%
ARP41543 White-tufted-ear marmoset CLCNKA antibody; Callithrix jacchus CLCNKA antibody H9KW34 86.0%
ARP41454 Zebra finch CLCNKA antibody; Taeniopygia guttata CLCNKA antibody H0YUX1 92.0%
ARP41454 Zebra finch CLCNKA antibody; Taeniopygia guttata CLCNKA antibody H0YUX6 92.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas207047_s_at721_B_lymphoblasts7.85013.080Details
BioGPS Gene Atlas207047_s_atAdipocyte7.15013.080Details
BioGPS Gene Atlas207047_s_atAdrenalCortex9.05013.080Details
BioGPS Gene Atlas207047_s_atAdrenalgland6.40013.080Details
BioGPS Gene Atlas207047_s_atAmygdala7.55013.080Details
BioGPS Gene Atlas207047_s_atAppendix9.05013.080Details
BioGPS Gene Atlas207047_s_atAtrioventricularNode6.55013.080Details
BioGPS Gene Atlas207047_s_atBDCA4+_DentriticCells7.00013.080Details
BioGPS Gene Atlas207047_s_atBonemarrow8.10013.080Details
BioGPS Gene Atlas207047_s_atBronchialEpithelialCells6.90013.080Details
BioGPS Gene Atlas207047_s_atCD105+_Endothelial7.40013.080Details
BioGPS Gene Atlas207047_s_atCD14+_Monocytes7.90013.080Details
BioGPS Gene Atlas207047_s_atCD19+_BCells(neg._sel.)7.55013.080Details
BioGPS Gene Atlas207047_s_atCD33+_Myeloid9.10013.080Details
BioGPS Gene Atlas207047_s_atCD34+8.70013.080Details
BioGPS Gene Atlas207047_s_atCD4+_Tcells7.75013.080Details
BioGPS Gene Atlas207047_s_atCD56+_NKCells8.20013.080Details
BioGPS Gene Atlas207047_s_atCD71+_EarlyErythroid7.35013.080Details
BioGPS Gene Atlas207047_s_atCD8+_Tcells6.80013.080Details
BioGPS Gene Atlas207047_s_atCardiacMyocytes12.85013.080Details
BioGPS Gene Atlas207047_s_atCaudatenucleus6.45013.080Details
BioGPS Gene Atlas207047_s_atCerebellum6.80013.080Details
BioGPS Gene Atlas207047_s_atCerebellumPeduncles10.50013.080Details
BioGPS Gene Atlas207047_s_atCiliaryGanglion6.10013.080Details
BioGPS Gene Atlas207047_s_atCingulateCortex8.05013.080Details
BioGPS Gene Atlas207047_s_atColorectaladenocarcinoma7.60013.080Details
BioGPS Gene Atlas207047_s_atDorsalRootGanglion6.00013.080Details
BioGPS Gene Atlas207047_s_atFetalThyroid8.60013.080Details
BioGPS Gene Atlas207047_s_atFetalbrain7.35013.080Details
BioGPS Gene Atlas207047_s_atFetalliver6.75013.080Details
BioGPS Gene Atlas207047_s_atFetallung5.65013.080Details
BioGPS Gene Atlas207047_s_atGlobusPallidus5.75013.080Details
BioGPS Gene Atlas207047_s_atHeart18.45013.080Details
BioGPS Gene Atlas207047_s_atHypothalamus7.95013.080Details
BioGPS Gene Atlas207047_s_atKidney381.15013.080Details
BioGPS Gene Atlas207047_s_atLeukemia_chronicMyelogenousK-5626.60013.080Details
BioGPS Gene Atlas207047_s_atLeukemia_promyelocytic-HL-606.60013.080Details
BioGPS Gene Atlas207047_s_atLeukemialymphoblastic(MOLT-4)5.75013.080Details
BioGPS Gene Atlas207047_s_atLiver15.25013.080Details
BioGPS Gene Atlas207047_s_atLung8.85013.080Details
BioGPS Gene Atlas207047_s_atLymphnode6.20013.080Details
BioGPS Gene Atlas207047_s_atLymphoma_burkitts(Daudi)9.90013.080Details
BioGPS Gene Atlas207047_s_atLymphoma_burkitts(Raji)12.70013.080Details
BioGPS Gene Atlas207047_s_atMedullaOblongata6.70013.080Details
BioGPS Gene Atlas207047_s_atOccipitalLobe6.75013.080Details
BioGPS Gene Atlas207047_s_atOlfactoryBulb5.95013.080Details
BioGPS Gene Atlas207047_s_atOvary5.65013.080Details
BioGPS Gene Atlas207047_s_atPancreas6.25013.080Details
BioGPS Gene Atlas207047_s_atPancreaticIslet8.30013.080Details
BioGPS Gene Atlas207047_s_atParietalLobe8.55013.080Details
BioGPS Gene Atlas207047_s_atPituitary11.50013.080Details
BioGPS Gene Atlas207047_s_atPlacenta7.30013.080Details
BioGPS Gene Atlas207047_s_atPons7.55013.080Details
BioGPS Gene Atlas207047_s_atPrefrontalCortex9.15013.080Details
BioGPS Gene Atlas207047_s_atProstate8.90013.080Details
BioGPS Gene Atlas207047_s_atSalivarygland6.50013.080Details
BioGPS Gene Atlas207047_s_atSkeletalMuscle11.90013.080Details
BioGPS Gene Atlas207047_s_atSkin6.70013.080Details
BioGPS Gene Atlas207047_s_atSmoothMuscle8.20013.080Details
BioGPS Gene Atlas207047_s_atSpinalcord7.85013.080Details
BioGPS Gene Atlas207047_s_atSubthalamicNucleus7.35013.080Details
BioGPS Gene Atlas207047_s_atSuperiorCervicalGanglion9.70013.080Details
BioGPS Gene Atlas207047_s_atTemporalLobe7.50013.080Details
BioGPS Gene Atlas207047_s_atTestis6.50013.080Details
BioGPS Gene Atlas207047_s_atTestisGermCell8.65013.080Details
BioGPS Gene Atlas207047_s_atTestisIntersitial6.60013.080Details
BioGPS Gene Atlas207047_s_atTestisLeydigCell7.85013.080Details
BioGPS Gene Atlas207047_s_atTestisSeminiferousTubule6.70013.080Details
BioGPS Gene Atlas207047_s_atThalamus7.65013.080Details
BioGPS Gene Atlas207047_s_atThymus5.55013.080Details
BioGPS Gene Atlas207047_s_atThyroid44.90013.080Details
BioGPS Gene Atlas207047_s_atTongue8.45013.080Details
BioGPS Gene Atlas207047_s_atTonsil7.55013.080Details
BioGPS Gene Atlas207047_s_atTrachea6.15013.080Details
BioGPS Gene Atlas207047_s_atTrigeminalGanglion9.45013.080Details
BioGPS Gene Atlas207047_s_atUterus6.10013.080Details
BioGPS Gene Atlas207047_s_atUterusCorpus14.80013.080Details
BioGPS Gene Atlas207047_s_atWholeBlood9.55013.080Details
BioGPS Gene Atlas207047_s_atWholebrain5.95013.080Details
BioGPS Gene Atlas207047_s_atcolon7.55013.080Details
BioGPS Gene Atlas207047_s_atpineal_day15.64013.080Details
BioGPS Gene Atlas207047_s_atpineal_night13.78013.080Details
BioGPS Gene Atlas207047_s_atretina9.10013.080Details
BioGPS Gene Atlas207047_s_atsmall_intestine7.15013.080Details
BioGPS NCI60207047_s_at7867.0407.120Details
BioGPS NCI60207047_s_atA1726.4157.120Details
BioGPS NCI60207047_s_atA2046.9337.120Details
BioGPS NCI60207047_s_atA3617.4087.120Details
BioGPS NCI60207047_s_atA4986.8987.120Details
BioGPS NCI60207047_s_atA5496.9587.120Details
BioGPS NCI60207047_s_atACC38.4097.120Details
BioGPS NCI60207047_s_atACHN6.0357.120Details
BioGPS NCI60207047_s_atALVA317.6137.120Details
BioGPS NCI60207047_s_atCAKI17.7937.120Details
BioGPS NCI60207047_s_atCCRT CEM10.2567.120Details
BioGPS NCI60207047_s_atCOLO2056.9927.120Details
BioGPS NCI60207047_s_atDLD16.7527.120Details
BioGPS NCI60207047_s_atDU1456.5237.120Details
BioGPS NCI60207047_s_atEKVX6.5127.120Details
BioGPS NCI60207047_s_atGM1337.4107.120Details
BioGPS NCI60207047_s_atGM16007.2597.120Details
BioGPS NCI60207047_s_atGM23137.1027.120Details
BioGPS NCI60207047_s_atGM23456.9317.120Details
BioGPS NCI60207047_s_atGM24937.2777.120Details
BioGPS NCI60207047_s_atGM9710.7337.120Details
BioGPS NCI60207047_s_atHCC29985.7017.120Details
BioGPS NCI60207047_s_atHCT1167.0627.120Details
BioGPS NCI60207047_s_atHCT156.1617.120Details
BioGPS NCI60207047_s_atHEK 293 T-rex7.8937.120Details
BioGPS NCI60207047_s_atHEK 293T6.9667.120Details
BioGPS NCI60207047_s_atHEK2936.9937.120Details
BioGPS NCI60207047_s_atHELA6.1377.120Details
BioGPS NCI60207047_s_atHEPG26.9117.120Details
BioGPS NCI60207047_s_atHL607.8857.120Details
BioGPS NCI60207047_s_atHOP627.0217.120Details
BioGPS NCI60207047_s_atHOP926.4927.120Details
BioGPS NCI60207047_s_atHS578T6.7437.120Details
BioGPS NCI60207047_s_atHSG6.5247.120Details
BioGPS NCI60207047_s_atHT10806.7497.120Details
BioGPS NCI60207047_s_atHT298.6587.120Details
BioGPS NCI60207047_s_atIGROV16.7887.120Details
BioGPS NCI60207047_s_atIOSE806.7827.120Details
BioGPS NCI60207047_s_atJURKAT6.9327.120Details
BioGPS NCI60207047_s_atK5628.7997.120Details
BioGPS NCI60207047_s_atKM127.8437.120Details
BioGPS NCI60207047_s_atLN186.3257.120Details
BioGPS NCI60207047_s_atLNCAP7.0347.120Details
BioGPS NCI60207047_s_atLOX IMVI6.9257.120Details
BioGPS NCI60207047_s_atM146.8507.120Details
BioGPS NCI60207047_s_atMALME 3M8.4517.120Details
BioGPS NCI60207047_s_atMCF76.5187.120Details
BioGPS NCI60207047_s_atMD MB2317.2597.120Details
BioGPS NCI60207047_s_atMDA MB4357.4887.120Details
BioGPS NCI60207047_s_atMOLT47.3087.120Details
BioGPS NCI60207047_s_atNCI 4607.1917.120Details
BioGPS NCI60207047_s_atNCI H2267.4787.120Details
BioGPS NCI60207047_s_atNCI H236.9767.120Details
BioGPS NCI60207047_s_atNCI H322M6.8657.120Details
BioGPS NCI60207047_s_atNCVADR RES6.3647.120Details
BioGPS NCI60207047_s_atOVCAR37.4877.120Details
BioGPS NCI60207047_s_atOVCAR46.9037.120Details
BioGPS NCI60207047_s_atOVCAR56.6777.120Details
BioGPS NCI60207047_s_atOVCAR86.1477.120Details
BioGPS NCI60207047_s_atPANC17.0657.120Details
BioGPS NCI60207047_s_atRL77.1267.120Details
BioGPS NCI60207047_s_atRPMI 82267.1567.120Details
BioGPS NCI60207047_s_atRS118468.0017.120Details
BioGPS NCI60207047_s_atRXF3936.8327.120Details
BioGPS NCI60207047_s_atSAOS27.0857.120Details
BioGPS NCI60207047_s_atSF2686.8947.120Details
BioGPS NCI60207047_s_atSF2956.5687.120Details
BioGPS NCI60207047_s_atSF5396.1247.120Details
BioGPS NCI60207047_s_atSHSYSY+RA6.5467.120Details
BioGPS NCI60207047_s_atSHSYSY-RA6.7537.120Details
BioGPS NCI60207047_s_atSKMEL26.8767.120Details
BioGPS NCI60207047_s_atSKMEL286.9747.120Details
BioGPS NCI60207047_s_atSKMEL56.2667.120Details
BioGPS NCI60207047_s_atSKOV37.1037.120Details
BioGPS NCI60207047_s_atSN12C6.8267.120Details
BioGPS NCI60207047_s_atSNB196.2147.120Details
BioGPS NCI60207047_s_atSNB756.8067.120Details
BioGPS NCI60207047_s_atSR7.5967.120Details
BioGPS NCI60207047_s_atSW6207.3727.120Details
BioGPS NCI60207047_s_atT247.2987.120Details
BioGPS NCI60207047_s_atT3M47.8557.120Details
BioGPS NCI60207047_s_atTK106.8727.120Details
BioGPS NCI60207047_s_atU1186.6577.120Details
BioGPS NCI60207047_s_atU1386.2917.120Details
BioGPS NCI60207047_s_atU20S9.6437.120Details
BioGPS NCI60207047_s_atU2516.7227.120Details
BioGPS NCI60207047_s_atU876.4407.120Details
BioGPS NCI60207047_s_atUACC2576.6587.120Details
BioGPS NCI60207047_s_atUACC627.2277.120Details
BioGPS NCI60207047_s_atUO316.4847.120Details
BioGPS NCI60207047_s_atZR75_17.7097.120Details
BioGPS NCI60207047_s_atastrocytes7.1497.120Details
BioGPS NCI60207047_s_athuh-77.5387.120Details