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Gene ID: 23529 | CLCF1 Antibody Resource


CLCF1 Antibody Resource
Gene Full Name: 
cardiotrophin-like cytokine factor 1
Uniprot: 
Q9UBD9
Protein Name: 
cardiotrophin-like cytokine factor 1
Nucleotide: 
XM_005273858
Alias: 
CLC;NR6;BSF3;NNT1;BSF-3;CISS2;NNT-1;
Ensembl: 
ENSG00000175505
Location: 
11q13.3
HPRD: 
09643
NCBI Gene: 
23529
MIM: 
607672

Summary: 
This gene is a member of the glycoprotein (gp)130 cytokine family and encodes cardiotrophin-like cytokine factor 1 (CLCF1). CLCF1 forms a heterodimer complex with cytokine receptor-like factor 1 (CRLF1). This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex, and activates the Jak-STAT signaling cascade. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. CLCF1 is a potent neurotrophic factor, B-cell stimulatory agent and neuroendocrine modulator of pituitary corticotroph function. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]
Function: 
Cytokine with B-cell stimulating capability. Binds to and activates the ILST/gp130 receptor.
Subcellular location: 
Secreted.
PTM: 
Glycoprotein;
Disease: 
Cold-induced sweating syndrome 2 (CISS2) [MIM:610313]: An autosomal recessive disorder characterized by profuse sweating induced by cool surroundings (temperatures of 7 to 18 degrees Celsius). Patients manifest, in the neonatal period, orofacial weakness with impaired sucking and swallowing, resulting in poor feeding. Affected infants show a tendency to startle, with contractions of the facial muscles in response to tactile stimuli or during crying, trismus, abundant salivation, and opisthotonus. These features are referred to as Crisponi syndrome and can result in early death in infancy. Patients who survive into childhood have hyperhidrosis, mainly of the upper body, in response to cold temperatures, and sweat very little with heat. Additional abnormalities include a high-arched palate, nasal voice, depressed nasal bridge, inability to fully extend the elbows and kyphoscoliosis. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP54917_P050 CLCF1 Antibody (ARP54917_P050) Polyclonal Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP54918_P050 CLCF1 Antibody (ARP54918_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB14312 CLCF1 antibody - N - terminal region (OAAB14312) Human WB 400ul $289 Details
Polyclonal Antibody OAGA00740 CLCF1 antibody (OAGA00740) Polyclonal Human ICC/IF, WB 100 ul $340 Details

Show all CLCF1 antibodies


Product Images
CLCF1 antibody - N - terminal region (OAAB14312) in A549 cells using Western Blot

Sample Type: A549


CLCF1 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP54918 Bovine CLCF1 antibody; Bos taurus CLCF1 antibody G3MXT9 93.0%
ARP54917 Cat CLCF1 antibody; Felis catus CLCF1 antibody M3WRH3 100.0%
ARP54918 Cat CLCF1 antibody; Felis catus CLCF1 antibody M3WRH3 100.0%
ARP54918 Chicken CLCF1 antibody; Gallus gallus CLCF1 antibody R4GIQ8 86.0%
ARP54917 Chimpanzee CLCF1 antibody; Pan troglodytes CLCF1 antibody K7CZW6 100.0%
ARP54918 Chimpanzee CLCF1 antibody; Pan troglodytes CLCF1 antibody K7CZW6 100.0%
ARP54918 Chinese softshell turtle CLCF1 antibody; Pelodiscus sinensis CLCF1 antibody K7GJA7 90.0%
ARP54918 Collared flycatcher CLCF1 antibody; Ficedula albicollis CLCF1 antibody U3KCL8 86.0%
ARP54917 Dog CLCF1 antibody; Canis familiaris CLCF1 antibody J9NXH8 100.0%
ARP54918 Dog CLCF1 antibody; Canis familiaris CLCF1 antibody J9NXH8 100.0%
ARP54917 Dog CLCF1 antibody; Canis familiaris CLCF1 antibody F1PDE0 100.0%
ARP54918 Dog CLCF1 antibody; Canis familiaris CLCF1 antibody F1PDE0 100.0%
ARP54918 Duckbill platypus CLCF1 antibody; Ornithorhynchus anatinus CLCF1 antibody F7DJ87 92.0%
ARP54917 European domestic ferret CLCF1 antibody; Mustela putorius furo CLCF1 antibody M3XXF3 100.0%
ARP54918 European domestic ferret CLCF1 antibody; Mustela putorius furo CLCF1 antibody M3XXF3 100.0%
ARP54917 Giant panda CLCF1 antibody; Ailuropoda melanoleuca CLCF1 antibody G1L1L5 100.0%
ARP54918 Giant panda CLCF1 antibody; Ailuropoda melanoleuca CLCF1 antibody G1L1L5 100.0%
ARP54917 Horse CLCF1 antibody; Equus caballus CLCF1 antibody F7B420 100.0%
ARP54918 Horse CLCF1 antibody; Equus caballus CLCF1 antibody F7B420 100.0%
ARP54917 Human CLCF1 antibody; Homo sapiens CLCF1 antibody Q9UBD9-2 100.0%
ARP54918 Human CLCF1 antibody; Homo sapiens CLCF1 antibody Q9UBD9-2 100.0%
ARP54917 Human CLCF1 antibody; Homo sapiens CLCF1 antibody Q9UBD9 100.0%
ARP54918 Human CLCF1 antibody; Homo sapiens CLCF1 antibody Q9UBD9 100.0%
ARP54917 Mouse CLCF1 antibody; Mus musculus CLCF1 antibody Q3TC09 100.0%
ARP54918 Mouse CLCF1 antibody; Mus musculus CLCF1 antibody Q3TC09 100.0%
ARP54917 Mouse CLCF1 antibody; Mus musculus CLCF1 antibody Q3TM06 100.0%
ARP54918 Mouse CLCF1 antibody; Mus musculus CLCF1 antibody Q3TM06 100.0%
ARP54917 Mouse CLCF1 antibody; Mus musculus CLCF1 antibody Q9QZM3 100.0%
ARP54918 Mouse CLCF1 antibody; Mus musculus CLCF1 antibody Q9QZM3 100.0%
ARP54918 Pig CLCF1 antibody; Sus scrofa CLCF1 antibody F1RUX6 100.0%
ARP54917 Pig CLCF1 antibody; Sus scrofa CLCF1 antibody F1RUX6 93.0%
ARP54917 Rabbit CLCF1 antibody; Oryctolagus cuniculus CLCF1 antibody G1SKR8 100.0%
ARP54918 Rabbit CLCF1 antibody; Oryctolagus cuniculus CLCF1 antibody G1SKR8 100.0%
ARP54917 Rat CLCF1 antibody; Rattus norvegicus CLCF1 antibody Q4KMB8 100.0%
ARP54918 Rat CLCF1 antibody; Rattus norvegicus CLCF1 antibody Q4KMB8 100.0%
ARP54918 Rat CLCF1 antibody; Rattus norvegicus CLCF1 antibody Q6UPE2 100.0%
ARP54917 Rat CLCF1 antibody; Rattus norvegicus CLCF1 antibody F7EKG3 100.0%
ARP54918 Rat CLCF1 antibody; Rattus norvegicus CLCF1 antibody F7EKG3 100.0%
ARP54917 Rat CLCF1 antibody; Rattus norvegicus CLCF1 antibody Q6UPE2 93.0%
ARP54917 Rhesus macaque CLCF1 antibody; Macaca mulatta CLCF1 antibody F7GWR7 100.0%
ARP54918 Rhesus macaque CLCF1 antibody; Macaca mulatta CLCF1 antibody F7GWR7 100.0%
ARP54917 Small-eared galago CLCF1 antibody; Otolemur garnettii CLCF1 antibody H0X355 100.0%
ARP54918 Small-eared galago CLCF1 antibody; Otolemur garnettii CLCF1 antibody H0X355 100.0%
ARP54918 Sumatran orangutan CLCF1 antibody; Pongo abelii CLCF1 antibody K7ET15 100.0%
ARP54917 Tasmanian devil CLCF1 antibody; Sarcophilus harrisii CLCF1 antibody G3VRA2 100.0%
ARP54918 Tasmanian devil CLCF1 antibody; Sarcophilus harrisii CLCF1 antibody G3VRA2 92.0%
ARP54917 Thirteen-lined ground squirrel CLCF1 antibody; Spermophilus tridecemlineatus CLCF1 antibody I3MQ74 100.0%
ARP54918 Thirteen-lined ground squirrel CLCF1 antibody; Spermophilus tridecemlineatus CLCF1 antibody I3MQ74 100.0%
ARP54918 White-tufted-ear marmoset CLCF1 antibody; Callithrix jacchus CLCF1 antibody F6VY17 100.0%
ARP54918 White-tufted-ear marmoset CLCF1 antibody; Callithrix jacchus CLCF1 antibody F7EZD5 100.0%
ARP54917 White-tufted-ear marmoset CLCF1 antibody; Callithrix jacchus CLCF1 antibody F6VY17 93.0%
ARP54917 White-tufted-ear marmoset CLCF1 antibody; Callithrix jacchus CLCF1 antibody F7EZD5 93.0%
ARP54918 Zebra finch CLCF1 antibody; Taeniopygia guttata CLCF1 antibody H0Z6S9 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas219500_at721_B_lymphoblasts10.2009.190Details
BioGPS Gene Atlas219500_atAdipocyte8.0009.190Details
BioGPS Gene Atlas219500_atAdrenalCortex11.9509.190Details
BioGPS Gene Atlas219500_atAdrenalgland6.6509.190Details
BioGPS Gene Atlas219500_atAmygdala6.7509.190Details
BioGPS Gene Atlas219500_atAppendix12.7009.190Details
BioGPS Gene Atlas219500_atAtrioventricularNode9.9009.190Details
BioGPS Gene Atlas219500_atBDCA4+_DentriticCells8.5009.190Details
BioGPS Gene Atlas219500_atBonemarrow8.1009.190Details
BioGPS Gene Atlas219500_atBronchialEpithelialCells7.7009.190Details
BioGPS Gene Atlas219500_atCD105+_Endothelial10.6009.190Details
BioGPS Gene Atlas219500_atCD14+_Monocytes8.8009.190Details
BioGPS Gene Atlas219500_atCD19+_BCells(neg._sel.)24.0009.190Details
BioGPS Gene Atlas219500_atCD33+_Myeloid10.5009.190Details
BioGPS Gene Atlas219500_atCD34+10.6509.190Details
BioGPS Gene Atlas219500_atCD4+_Tcells8.9509.190Details
BioGPS Gene Atlas219500_atCD56+_NKCells9.8509.190Details
BioGPS Gene Atlas219500_atCD71+_EarlyErythroid7.7009.190Details
BioGPS Gene Atlas219500_atCD8+_Tcells9.0509.190Details
BioGPS Gene Atlas219500_atCardiacMyocytes9.8509.190Details
BioGPS Gene Atlas219500_atCaudatenucleus7.2509.190Details
BioGPS Gene Atlas219500_atCerebellum7.4509.190Details
BioGPS Gene Atlas219500_atCerebellumPeduncles18.2509.190Details
BioGPS Gene Atlas219500_atCiliaryGanglion7.0009.190Details
BioGPS Gene Atlas219500_atCingulateCortex9.0009.190Details
BioGPS Gene Atlas219500_atColorectaladenocarcinoma9.6009.190Details
BioGPS Gene Atlas219500_atDorsalRootGanglion7.7509.190Details
BioGPS Gene Atlas219500_atFetalThyroid9.1509.190Details
BioGPS Gene Atlas219500_atFetalbrain7.7009.190Details
BioGPS Gene Atlas219500_atFetalliver7.0009.190Details
BioGPS Gene Atlas219500_atFetallung6.0509.190Details
BioGPS Gene Atlas219500_atGlobusPallidus6.5509.190Details
BioGPS Gene Atlas219500_atHeart13.7009.190Details
BioGPS Gene Atlas219500_atHypothalamus8.9509.190Details
BioGPS Gene Atlas219500_atKidney6.5509.190Details
BioGPS Gene Atlas219500_atLeukemia_chronicMyelogenousK-5627.9509.190Details
BioGPS Gene Atlas219500_atLeukemia_promyelocytic-HL-606.9509.190Details
BioGPS Gene Atlas219500_atLeukemialymphoblastic(MOLT-4)6.3009.190Details
BioGPS Gene Atlas219500_atLiver11.0009.190Details
BioGPS Gene Atlas219500_atLung8.4009.190Details
BioGPS Gene Atlas219500_atLymphnode6.4509.190Details
BioGPS Gene Atlas219500_atLymphoma_burkitts(Daudi)10.4509.190Details
BioGPS Gene Atlas219500_atLymphoma_burkitts(Raji)12.7509.190Details
BioGPS Gene Atlas219500_atMedullaOblongata7.5009.190Details
BioGPS Gene Atlas219500_atOccipitalLobe7.2509.190Details
BioGPS Gene Atlas219500_atOlfactoryBulb7.3509.190Details
BioGPS Gene Atlas219500_atOvary7.6009.190Details
BioGPS Gene Atlas219500_atPancreas6.6009.190Details
BioGPS Gene Atlas219500_atPancreaticIslet8.5009.190Details
BioGPS Gene Atlas219500_atParietalLobe8.4009.190Details
BioGPS Gene Atlas219500_atPituitary9.2009.190Details
BioGPS Gene Atlas219500_atPlacenta7.0509.190Details
BioGPS Gene Atlas219500_atPons7.8009.190Details
BioGPS Gene Atlas219500_atPrefrontalCortex9.4509.190Details
BioGPS Gene Atlas219500_atProstate9.0509.190Details
BioGPS Gene Atlas219500_atSalivarygland8.6009.190Details
BioGPS Gene Atlas219500_atSkeletalMuscle13.2009.190Details
BioGPS Gene Atlas219500_atSkin6.9009.190Details
BioGPS Gene Atlas219500_atSmoothMuscle9.2009.190Details
BioGPS Gene Atlas219500_atSpinalcord8.6009.190Details
BioGPS Gene Atlas219500_atSubthalamicNucleus7.5009.190Details
BioGPS Gene Atlas219500_atSuperiorCervicalGanglion11.2509.190Details
BioGPS Gene Atlas219500_atTemporalLobe7.9509.190Details
BioGPS Gene Atlas219500_atTestis6.7509.190Details
BioGPS Gene Atlas219500_atTestisGermCell6.7509.190Details
BioGPS Gene Atlas219500_atTestisIntersitial7.8509.190Details
BioGPS Gene Atlas219500_atTestisLeydigCell8.0509.190Details
BioGPS Gene Atlas219500_atTestisSeminiferousTubule10.8509.190Details
BioGPS Gene Atlas219500_atThalamus8.3009.190Details
BioGPS Gene Atlas219500_atThymus5.3509.190Details
BioGPS Gene Atlas219500_atThyroid9.0009.190Details
BioGPS Gene Atlas219500_atTongue10.3509.190Details
BioGPS Gene Atlas219500_atTonsil8.1009.190Details
BioGPS Gene Atlas219500_atTrachea8.1009.190Details
BioGPS Gene Atlas219500_atTrigeminalGanglion11.8509.190Details
BioGPS Gene Atlas219500_atUterus6.4009.190Details
BioGPS Gene Atlas219500_atUterusCorpus23.0009.190Details
BioGPS Gene Atlas219500_atWholeBlood10.4009.190Details
BioGPS Gene Atlas219500_atWholebrain4.9509.190Details
BioGPS Gene Atlas219500_atcolon8.0509.190Details
BioGPS Gene Atlas219500_atpineal_day10.6009.190Details
BioGPS Gene Atlas219500_atpineal_night11.5209.190Details
BioGPS Gene Atlas219500_atretina10.3759.190Details
BioGPS Gene Atlas219500_atsmall_intestine7.3509.190Details
BioGPS NCI60219500_at78626.07929.260Details
BioGPS NCI60219500_atA17217.26529.260Details
BioGPS NCI60219500_atA20425.34229.260Details
BioGPS NCI60219500_atA36125.50729.260Details
BioGPS NCI60219500_atA49825.50229.260Details
BioGPS NCI60219500_atA54927.91029.260Details
BioGPS NCI60219500_atACC332.19829.260Details
BioGPS NCI60219500_atACHN37.86329.260Details
BioGPS NCI60219500_atALVA3125.74829.260Details
BioGPS NCI60219500_atCAKI129.44829.260Details
BioGPS NCI60219500_atCCRT CEM27.76329.260Details
BioGPS NCI60219500_atCOLO20525.54829.260Details
BioGPS NCI60219500_atDLD125.01529.260Details
BioGPS NCI60219500_atDU14553.20529.260Details
BioGPS NCI60219500_atEKVX131.03429.260Details
BioGPS NCI60219500_atGM13319.11629.260Details
BioGPS NCI60219500_atGM160027.32329.260Details
BioGPS NCI60219500_atGM231330.60929.260Details
BioGPS NCI60219500_atGM234525.61629.260Details
BioGPS NCI60219500_atGM249337.44229.260Details
BioGPS NCI60219500_atGM9784.86129.260Details
BioGPS NCI60219500_atHCC299815.93429.260Details
BioGPS NCI60219500_atHCT11625.25929.260Details
BioGPS NCI60219500_atHCT1515.40229.260Details
BioGPS NCI60219500_atHEK 293 T-rex28.63329.260Details
BioGPS NCI60219500_atHEK 293T18.18929.260Details
BioGPS NCI60219500_atHEK29320.78729.260Details
BioGPS NCI60219500_atHELA21.47629.260Details
BioGPS NCI60219500_atHEPG216.28529.260Details
BioGPS NCI60219500_atHL6018.74229.260Details
BioGPS NCI60219500_atHOP6232.05229.260Details
BioGPS NCI60219500_atHOP9265.01129.260Details
BioGPS NCI60219500_atHS578T25.05329.260Details
BioGPS NCI60219500_atHSG29.57829.260Details
BioGPS NCI60219500_atHT108017.91529.260Details
BioGPS NCI60219500_atHT2926.91829.260Details
BioGPS NCI60219500_atIGROV136.73429.260Details
BioGPS NCI60219500_atIOSE8025.51129.260Details
BioGPS NCI60219500_atJURKAT20.40129.260Details
BioGPS NCI60219500_atK56226.85729.260Details
BioGPS NCI60219500_atKM1228.18929.260Details
BioGPS NCI60219500_atLN1816.74729.260Details
BioGPS NCI60219500_atLNCAP24.86729.260Details
BioGPS NCI60219500_atLOX IMVI25.35129.260Details
BioGPS NCI60219500_atM1416.71929.260Details
BioGPS NCI60219500_atMALME 3M25.91829.260Details
BioGPS NCI60219500_atMCF716.04729.260Details
BioGPS NCI60219500_atMD MB23133.46429.260Details
BioGPS NCI60219500_atMDA MB43525.77729.260Details
BioGPS NCI60219500_atMOLT425.64229.260Details
BioGPS NCI60219500_atNCI 46025.24029.260Details
BioGPS NCI60219500_atNCI H22632.83729.260Details
BioGPS NCI60219500_atNCI H2333.85829.260Details
BioGPS NCI60219500_atNCI H322M22.25329.260Details
BioGPS NCI60219500_atNCVADR RES25.12129.260Details
BioGPS NCI60219500_atOVCAR346.47729.260Details
BioGPS NCI60219500_atOVCAR425.29229.260Details
BioGPS NCI60219500_atOVCAR523.78829.260Details
BioGPS NCI60219500_atOVCAR871.24629.260Details
BioGPS NCI60219500_atPANC124.90429.260Details
BioGPS NCI60219500_atRL725.12229.260Details
BioGPS NCI60219500_atRPMI 822625.04529.260Details
BioGPS NCI60219500_atRS1184626.46429.260Details
BioGPS NCI60219500_atRXF39341.08029.260Details
BioGPS NCI60219500_atSAOS225.13229.260Details
BioGPS NCI60219500_atSF26833.93729.260Details
BioGPS NCI60219500_atSF29525.03629.260Details
BioGPS NCI60219500_atSF53927.03629.260Details
BioGPS NCI60219500_atSHSYSY+RA18.05129.260Details
BioGPS NCI60219500_atSHSYSY-RA17.00929.260Details
BioGPS NCI60219500_atSKMEL213.38829.260Details
BioGPS NCI60219500_atSKMEL2825.35229.260Details
BioGPS NCI60219500_atSKMEL516.95929.260Details
BioGPS NCI60219500_atSKOV326.21129.260Details
BioGPS NCI60219500_atSN12C16.00829.260Details
BioGPS NCI60219500_atSNB1925.31229.260Details
BioGPS NCI60219500_atSNB7534.88729.260Details
BioGPS NCI60219500_atSR18.45429.260Details
BioGPS NCI60219500_atSW62025.58329.260Details
BioGPS NCI60219500_atT2426.02829.260Details
BioGPS NCI60219500_atT3M425.74229.260Details
BioGPS NCI60219500_atTK1039.00429.260Details
BioGPS NCI60219500_atU11831.85529.260Details
BioGPS NCI60219500_atU13852.36129.260Details
BioGPS NCI60219500_atU20S20.96129.260Details
BioGPS NCI60219500_atU25125.31629.260Details
BioGPS NCI60219500_atU8757.71829.260Details
BioGPS NCI60219500_atUACC25724.77029.260Details
BioGPS NCI60219500_atUACC6216.48629.260Details
BioGPS NCI60219500_atUO3130.02129.260Details
BioGPS NCI60219500_atZR75_125.13329.260Details
BioGPS NCI60219500_atastrocytes37.76129.260Details
BioGPS NCI60219500_athuh-725.73229.260Details