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Gene ID: 10519 | Cib1 Antibody Resource


Cib1 Antibody Resource
Gene Full Name: 
calcium and integrin binding 1 (calmyrin)
Uniprot: 
Q99828
Protein Name: 
calcium and integrin-binding protein 1
Nucleotide: 
NR_102428
Alias: 
CIB;CIBP;KIP1;PRKDCIP;SIP2-28;
Ensembl: 
Location: 
15q25.3-q26
HPRD: 
03800
NCBI Gene: 
10519
MIM: 
602293

Summary: 
This gene encodes a member of the EF-hand domain-containing calcium-binding superfamily. The encoded protein interacts with many other proteins, including the platelet integrin alpha-IIb-beta-3, DNA-dependent protein kinase, presenilin-2, focal adhesion kinase, p21 activated kinase, and protein kinase D. The encoded protein may be involved in cell survival and proliferation, and is associated with several disease states including cancer and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
Function: 
May convert the inactive conformation of integrin alpha-IIb/beta3 to an active form through binding to the integrin cytoplasmic domain. Induces cell migration and spreading mediated through integrin (possibly via focal adhesion complexes). Functions as a negative regulator of stress activated MAP kinase (MAPK) signaling pathways. May play a role in regulation of apoptosis. Interacts with and up-regulates PTK2/FAK1 activity. Down regulates inositol 1,4,5-trisphosphate receptor-dependent calcium signaling. Participates in endomitotic cell cycle, a form of mitosis in which both karyokinesis and cytokinesis are interrupted and is a hallmark of megakaryocyte differentiation.
Subcellular location: 
Membrane; Lipid-anchor. Cytoplasm. Nucleus. Cell projection › filopodium. Apical cell membrane. Note: Localizes to the perinuclear region in the presence of NBR1. Colocalizes with TAS1R2 in apical regions of taste receptor cells.
PTM: 
Lipoprotein;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Monoclonal Antibody OAPA00215 CIB1 Antibody (OAPA00215) Monoclonal ELISA, WB 5ug $100 Details
Protein OPPA01707 CIB1 Human - Recombinant Human Calcium and Integrin Binding 1 (5ug) 5ug $100 Details
Polyclonal Antibody ARP48297_P050 Cib1 Antibody - N-terminal region (ARP48297_P050) Rat; Human WB 50ug $289 Details
Polyclonal Antibody OAAB15410 CIB1 antibody - C - terminal region (OAAB15410) Human WB 400ul $289 Details

Show all Cib1 antibodies


Product Images
Cib1 Antibody - N-terminal region (ARP48297_P050) in Rat Muscle cells using Western Blot

Sample Type: Rat Muscle

CIB1 antibody - C - terminal region (OAAB15410) in NCI-H292 cells using Western Blot

Sample Type: NCI-H292


Cib1 Protocols

Publications

Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP52491 Atlantic salmon Cib1 antibody; Salmo salar Cib1 antibody B9EN53 83.0%
ARP52491 Atlantic salmon Cib1 antibody; Salmo salar Cib1 antibody B9EN88 83.0%
ARP52491 Atlantic salmon Cib1 antibody; Salmo salar Cib1 antibody B9ENZ6 83.0%
ARP48297 Bovine Cib1 antibody; Bos taurus Cib1 antibody Q17QE5 100.0%
ARP48297 Chimpanzee Cib1 antibody; Pan troglodytes Cib1 antibody H2QA31 100.0%
ARP48297 Dog Cib1 antibody; Canis familiaris Cib1 antibody E2RRH5 100.0%
ARP48297 European domestic ferret Cib1 antibody; Mustela putorius furo Cib1 antibody M3YWB3 93.0%
ARP48297 Horse Cib1 antibody; Equus caballus Cib1 antibody F7CUM5 93.0%
ARP48297 Human Cib1 antibody; Homo sapiens Cib1 antibody Q99828 100.0%
ARP48297 Mouse Cib1 antibody; Mus musculus Cib1 antibody Q8C2K4 100.0%
ARP48297 Mouse Cib1 antibody; Mus musculus Cib1 antibody Q9Z0F4 100.0%
ARP48297 Pig Cib1 antibody; Sus scrofa Cib1 antibody F1SJX5 100.0%
ARP48297 Rat Cib1 antibody; Rattus norvegicus Cib1 antibody Q9R010 100.0%
ARP48297 Rhesus macaque Cib1 antibody; Macaca mulatta Cib1 antibody F7FRX2 100.0%
ARP48297 Rhesus macaque Cib1 antibody; Macaca mulatta Cib1 antibody G7MVY1 100.0%
ARP52491 Sablefish Cib1 antibody; Anoplopoma fimbria Cib1 antibody C3KGT4 83.0%
ARP52491 Sablefish Cib1 antibody; Anoplopoma fimbria Cib1 antibody C3KIP8 83.0%
ARP52491 Sablefish Cib1 antibody; Anoplopoma fimbria Cib1 antibody C3KJ83 83.0%
ARP48297 Sheep Cib1 antibody; Ovis aries Cib1 antibody B1A8Z2 100.0%
ARP48297 Small-eared galago Cib1 antibody; Otolemur garnettii Cib1 antibody H0X0M6 93.0%
ARP52491 Spotted green pufferfish Cib1 antibody; Tetraodon nigroviridis Cib1 antibody Q4S7D6 92.0%
ARP48297 Sumatran orangutan Cib1 antibody; Pongo abelii Cib1 antibody H2NP66 100.0%
ARP52491 Tasmanian devil Cib1 antibody; Sarcophilus harrisii Cib1 antibody G3WC54 83.0%
ARP48297 Thirteen-lined ground squirrel Cib1 antibody; Spermophilus tridecemlineatus Cib1 antibody I3MEN3 100.0%
ARP48297 White-tufted-ear marmoset Cib1 antibody; Callithrix jacchus Cib1 antibody U3D650 100.0%
ARP48297 White-tufted-ear marmoset Cib1 antibody; Callithrix jacchus Cib1 antibody U3CRP8 93.0%
ARP52491 Zebrafish Cib1 antibody; Danio rerio Cib1 antibody Q567I6 83.0%
ARP52491 Zebrafish Cib1 antibody; Danio rerio Cib1 antibody F1Q5E1 83.0%
ARP52491 Zebrafish Cib1 antibody; Danio rerio Cib1 antibody F1QAZ0 83.0%
ARP52491 Zebrafish Cib1 antibody; Danio rerio Cib1 antibody F1QCE4 83.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas201953_at721_B_lymphoblasts325.400249.890Details
BioGPS Gene Atlas201953_atAdipocyte200.050249.890Details
BioGPS Gene Atlas201953_atAdrenalCortex384.050249.890Details
BioGPS Gene Atlas201953_atAdrenalgland386.800249.890Details
BioGPS Gene Atlas201953_atAmygdala52.650249.890Details
BioGPS Gene Atlas201953_atAppendix44.700249.890Details
BioGPS Gene Atlas201953_atAtrioventricularNode22.250249.890Details
BioGPS Gene Atlas201953_atBDCA4+_DentriticCells329.400249.890Details
BioGPS Gene Atlas201953_atBonemarrow155.300249.890Details
BioGPS Gene Atlas201953_atBronchialEpithelialCells565.450249.890Details
BioGPS Gene Atlas201953_atCD105+_Endothelial258.300249.890Details
BioGPS Gene Atlas201953_atCD14+_Monocytes545.400249.890Details
BioGPS Gene Atlas201953_atCD19+_BCells(neg._sel.)761.450249.890Details
BioGPS Gene Atlas201953_atCD33+_Myeloid281.400249.890Details
BioGPS Gene Atlas201953_atCD34+204.350249.890Details
BioGPS Gene Atlas201953_atCD4+_Tcells679.650249.890Details
BioGPS Gene Atlas201953_atCD56+_NKCells616.250249.890Details
BioGPS Gene Atlas201953_atCD71+_EarlyErythroid73.900249.890Details
BioGPS Gene Atlas201953_atCD8+_Tcells539.750249.890Details
BioGPS Gene Atlas201953_atCardiacMyocytes165.400249.890Details
BioGPS Gene Atlas201953_atCaudatenucleus41.200249.890Details
BioGPS Gene Atlas201953_atCerebellum22.950249.890Details
BioGPS Gene Atlas201953_atCerebellumPeduncles27.250249.890Details
BioGPS Gene Atlas201953_atCiliaryGanglion28.900249.890Details
BioGPS Gene Atlas201953_atCingulateCortex39.050249.890Details
BioGPS Gene Atlas201953_atColorectaladenocarcinoma169.600249.890Details
BioGPS Gene Atlas201953_atDorsalRootGanglion17.050249.890Details
BioGPS Gene Atlas201953_atFetalThyroid261.000249.890Details
BioGPS Gene Atlas201953_atFetalbrain17.750249.890Details
BioGPS Gene Atlas201953_atFetalliver46.900249.890Details
BioGPS Gene Atlas201953_atFetallung187.800249.890Details
BioGPS Gene Atlas201953_atGlobusPallidus19.800249.890Details
BioGPS Gene Atlas201953_atHeart1257.400249.890Details
BioGPS Gene Atlas201953_atHypothalamus89.500249.890Details
BioGPS Gene Atlas201953_atKidney349.250249.890Details
BioGPS Gene Atlas201953_atLeukemia_chronicMyelogenousK-56289.050249.890Details
BioGPS Gene Atlas201953_atLeukemia_promyelocytic-HL-60123.150249.890Details
BioGPS Gene Atlas201953_atLeukemialymphoblastic(MOLT-4)189.500249.890Details
BioGPS Gene Atlas201953_atLiver1080.100249.890Details
BioGPS Gene Atlas201953_atLung1037.550249.890Details
BioGPS Gene Atlas201953_atLymphnode289.050249.890Details
BioGPS Gene Atlas201953_atLymphoma_burkitts(Daudi)52.650249.890Details
BioGPS Gene Atlas201953_atLymphoma_burkitts(Raji)154.650249.890Details
BioGPS Gene Atlas201953_atMedullaOblongata47.300249.890Details
BioGPS Gene Atlas201953_atOccipitalLobe52.450249.890Details
BioGPS Gene Atlas201953_atOlfactoryBulb46.550249.890Details
BioGPS Gene Atlas201953_atOvary28.200249.890Details
BioGPS Gene Atlas201953_atPancreas206.650249.890Details
BioGPS Gene Atlas201953_atPancreaticIslet706.750249.890Details
BioGPS Gene Atlas201953_atParietalLobe42.800249.890Details
BioGPS Gene Atlas201953_atPituitary128.550249.890Details
BioGPS Gene Atlas201953_atPlacenta93.700249.890Details
BioGPS Gene Atlas201953_atPons39.550249.890Details
BioGPS Gene Atlas201953_atPrefrontalCortex110.350249.890Details
BioGPS Gene Atlas201953_atProstate1512.550249.890Details
BioGPS Gene Atlas201953_atSalivarygland136.800249.890Details
BioGPS Gene Atlas201953_atSkeletalMuscle33.150249.890Details
BioGPS Gene Atlas201953_atSkin32.600249.890Details
BioGPS Gene Atlas201953_atSmoothMuscle251.650249.890Details
BioGPS Gene Atlas201953_atSpinalcord109.550249.890Details
BioGPS Gene Atlas201953_atSubthalamicNucleus38.450249.890Details
BioGPS Gene Atlas201953_atSuperiorCervicalGanglion30.350249.890Details
BioGPS Gene Atlas201953_atTemporalLobe42.100249.890Details
BioGPS Gene Atlas201953_atTestis375.400249.890Details
BioGPS Gene Atlas201953_atTestisGermCell403.900249.890Details
BioGPS Gene Atlas201953_atTestisIntersitial395.000249.890Details
BioGPS Gene Atlas201953_atTestisLeydigCell364.700249.890Details
BioGPS Gene Atlas201953_atTestisSeminiferousTubule302.500249.890Details
BioGPS Gene Atlas201953_atThalamus65.450249.890Details
BioGPS Gene Atlas201953_atThymus290.150249.890Details
BioGPS Gene Atlas201953_atThyroid708.500249.890Details
BioGPS Gene Atlas201953_atTongue58.250249.890Details
BioGPS Gene Atlas201953_atTonsil277.450249.890Details
BioGPS Gene Atlas201953_atTrachea327.900249.890Details
BioGPS Gene Atlas201953_atTrigeminalGanglion32.050249.890Details
BioGPS Gene Atlas201953_atUterus122.200249.890Details
BioGPS Gene Atlas201953_atUterusCorpus42.350249.890Details
BioGPS Gene Atlas201953_atWholeBlood348.350249.890Details
BioGPS Gene Atlas201953_atWholebrain142.700249.890Details
BioGPS Gene Atlas201953_atcolon535.650249.890Details
BioGPS Gene Atlas201953_atpineal_day98.420249.890Details
BioGPS Gene Atlas201953_atpineal_night135.920249.890Details
BioGPS Gene Atlas201953_atretina206.800249.890Details
BioGPS Gene Atlas201953_atsmall_intestine325.400249.890Details
BioGPS NCI60201953_at7862154.657946.590Details
BioGPS NCI60201953_atA172745.905946.590Details
BioGPS NCI60201953_atA204286.151946.590Details
BioGPS NCI60201953_atA361503.995946.590Details
BioGPS NCI60201953_atA4983597.973946.590Details
BioGPS NCI60201953_atA5492074.167946.590Details
BioGPS NCI60201953_atACC32038.465946.590Details
BioGPS NCI60201953_atACHN1188.314946.590Details
BioGPS NCI60201953_atALVA31889.106946.590Details
BioGPS NCI60201953_atCAKI1965.724946.590Details
BioGPS NCI60201953_atCCRT CEM322.360946.590Details
BioGPS NCI60201953_atCOLO2051618.200946.590Details
BioGPS NCI60201953_atDLD1562.315946.590Details
BioGPS NCI60201953_atDU1452029.570946.590Details
BioGPS NCI60201953_atEKVX1261.920946.590Details
BioGPS NCI60201953_atGM133795.167946.590Details
BioGPS NCI60201953_atGM1600571.487946.590Details
BioGPS NCI60201953_atGM2313769.085946.590Details
BioGPS NCI60201953_atGM2345639.419946.590Details
BioGPS NCI60201953_atGM24931031.389946.590Details
BioGPS NCI60201953_atGM97869.069946.590Details
BioGPS NCI60201953_atHCC2998988.258946.590Details
BioGPS NCI60201953_atHCT1161051.714946.590Details
BioGPS NCI60201953_atHCT151077.502946.590Details
BioGPS NCI60201953_atHEK 293 T-rex559.352946.590Details
BioGPS NCI60201953_atHEK 293T283.339946.590Details
BioGPS NCI60201953_atHEK293515.433946.590Details
BioGPS NCI60201953_atHELA1194.881946.590Details
BioGPS NCI60201953_atHEPG2979.354946.590Details
BioGPS NCI60201953_atHL60379.815946.590Details
BioGPS NCI60201953_atHOP621142.231946.590Details
BioGPS NCI60201953_atHOP92791.974946.590Details
BioGPS NCI60201953_atHS578T449.786946.590Details
BioGPS NCI60201953_atHSG1495.959946.590Details
BioGPS NCI60201953_atHT1080262.552946.590Details
BioGPS NCI60201953_atHT291124.205946.590Details
BioGPS NCI60201953_atIGROV12084.762946.590Details
BioGPS NCI60201953_atIOSE80641.394946.590Details
BioGPS NCI60201953_atJURKAT1362.766946.590Details
BioGPS NCI60201953_atK562709.352946.590Details
BioGPS NCI60201953_atKM121619.269946.590Details
BioGPS NCI60201953_atLN18617.049946.590Details
BioGPS NCI60201953_atLNCAP1615.772946.590Details
BioGPS NCI60201953_atLOX IMVI1311.090946.590Details
BioGPS NCI60201953_atM141138.250946.590Details
BioGPS NCI60201953_atMALME 3M390.824946.590Details
BioGPS NCI60201953_atMCF71622.444946.590Details
BioGPS NCI60201953_atMD MB231705.403946.590Details
BioGPS NCI60201953_atMDA MB4351094.694946.590Details
BioGPS NCI60201953_atMOLT41122.471946.590Details
BioGPS NCI60201953_atNCI 4601138.738946.590Details
BioGPS NCI60201953_atNCI H226787.048946.590Details
BioGPS NCI60201953_atNCI H23444.333946.590Details
BioGPS NCI60201953_atNCI H322M1470.503946.590Details
BioGPS NCI60201953_atNCVADR RES704.517946.590Details
BioGPS NCI60201953_atOVCAR31266.851946.590Details
BioGPS NCI60201953_atOVCAR4507.624946.590Details
BioGPS NCI60201953_atOVCAR51027.003946.590Details
BioGPS NCI60201953_atOVCAR8446.860946.590Details
BioGPS NCI60201953_atPANC13593.267946.590Details
BioGPS NCI60201953_atRL7683.256946.590Details
BioGPS NCI60201953_atRPMI 8226914.327946.590Details
BioGPS NCI60201953_atRS11846560.052946.590Details
BioGPS NCI60201953_atRXF393833.439946.590Details
BioGPS NCI60201953_atSAOS2256.049946.590Details
BioGPS NCI60201953_atSF268448.182946.590Details
BioGPS NCI60201953_atSF295819.018946.590Details
BioGPS NCI60201953_atSF539688.371946.590Details
BioGPS NCI60201953_atSHSYSY+RA92.071946.590Details
BioGPS NCI60201953_atSHSYSY-RA165.870946.590Details
BioGPS NCI60201953_atSKMEL2607.419946.590Details
BioGPS NCI60201953_atSKMEL281472.710946.590Details
BioGPS NCI60201953_atSKMEL5727.201946.590Details
BioGPS NCI60201953_atSKOV3670.769946.590Details
BioGPS NCI60201953_atSN12C749.612946.590Details
BioGPS NCI60201953_atSNB19799.657946.590Details
BioGPS NCI60201953_atSNB75385.216946.590Details
BioGPS NCI60201953_atSR1460.885946.590Details
BioGPS NCI60201953_atSW620749.121946.590Details
BioGPS NCI60201953_atT241454.011946.590Details
BioGPS NCI60201953_atT3M42486.199946.590Details
BioGPS NCI60201953_atTK101103.813946.590Details
BioGPS NCI60201953_atU1181303.329946.590Details
BioGPS NCI60201953_atU138950.952946.590Details
BioGPS NCI60201953_atU20S480.411946.590Details
BioGPS NCI60201953_atU2511172.789946.590Details
BioGPS NCI60201953_atU871191.186946.590Details
BioGPS NCI60201953_atUACC257468.996946.590Details
BioGPS NCI60201953_atUACC62615.420946.590Details
BioGPS NCI60201953_atUO311063.466946.590Details
BioGPS NCI60201953_atZR75_11222.219946.590Details
BioGPS NCI60201953_atastrocytes73.912946.590Details
BioGPS NCI60201953_athuh-7772.449946.590Details