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Gene ID: 22856 | CHSY1 Antibody Resource


CHSY1 Antibody Resource
Gene Full Name: 
chondroitin sulfate synthase 1
Uniprot: 
Q86X52
Protein Name: 
chondroitin sulfate synthase 1
Nucleotide: 
NM_014918
Alias: 
CHSY;CSS1;TPBS;ChSy-1;
Ensembl: 
ENSG00000131873
Location: 
15q26.3
HPRD: 
10493
NCBI Gene: 
22856
MIM: 
608183

Summary: 
This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. These enzymes possess dual glucuronyltransferase and galactosaminyltransferase activity and play critical roles in the biosynthesis of chondroitin sulfate, a glycosaminoglycan involved in many biological processes including cell proliferation and morphogenesis. Decreased expression of this gene may play a role in colorectal cancer, and mutations in this gene are a cause of temtamy preaxial brachydactyly syndrome. [provided by RefSeq, Dec 2011]
Function: 
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.
Subcellular location: 
Golgi apparatus › Golgi stack membrane; Single-pass type II membrane protein Probable. Secreted .
PTM: 
Glycoprotein;
Disease: 
Temtamy preaxial brachydactyly syndrome (TPBS) [MIM:605282]: A syndrome characterized by multiple congenital anomalies, mental retardation, sensorineural deafness, talon cusps of upper central incisors, growth retardation, and bilateral symmetric digital anomalies mainly in the form of preaxial brachydactyly and hyperphalangism. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP47099_P050 CHSY1 Antibody (ARP47099_P050) Polyclonal Human Not tested 50 ug $125 Details
Polyclonal Antibody OAAB09887 CHSY1 antibody - center region (OAAB09887) Human; Mouse WB, FC 400ul $289 Details
Polyclonal Antibody OAAF03493 CHSY1 Antibody (OAAF03493) Polyclonal Human, Mouse WB, IHC, ELISA 100 ug $229 Details

Show all CHSY1 antibodies


Product Images
CHSY1 antibody - center region (OAAB09887) in Mouse Neuro-2a cells using Western Blot

Sample Type: Mouse Neuro-2a

 CHSY1 antibody - center region (OAAB09887) in NCI-H460 cells using Western Blot

Sample Type: NCI-H460

 CHSY1 antibody - center region (OAAB09887) in Neuro-2a cells using Flow Cytometry

Sample Type: Neuro-2a

 CHSY1 Antibody (OAAF03493) in HepG2, K562 cells using Western Blot

Sample Type: HepG2, K562

 CHSY1 Antibody (OAAF03493) in Human brain cells using Immunohistochemistry

Sample Type: Human brain

CHSY1 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP47099 Chimpanzee CHSY1 antibody; Pan troglodytes CHSY1 antibody K7C1E9 100.0%
ARP47099 Chimpanzee CHSY1 antibody; Pan troglodytes CHSY1 antibody K7D3N2 100.0%
ARP47099 Human CHSY1 antibody; Homo sapiens CHSY1 antibody Q86X52 100.0%
ARP47099 Rhesus macaque CHSY1 antibody; Macaca mulatta CHSY1 antibody F7H7B4 100.0%
ARP47099 Rhesus macaque CHSY1 antibody; Macaca mulatta CHSY1 antibody I2CWP0 100.0%
ARP47099 Small-eared galago CHSY1 antibody; Otolemur garnettii CHSY1 antibody H0WNJ9 79.0%
ARP47099 Thirteen-lined ground squirrel CHSY1 antibody; Spermophilus tridecemlineatus CHSY1 antibody I3MCS8 92.0%
ARP47099 White-tufted-ear marmoset CHSY1 antibody; Callithrix jacchus CHSY1 antibody F7HW16 79.0%
ARP47099 White-tufted-ear marmoset CHSY1 antibody; Callithrix jacchus CHSY1 antibody F7HY89 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas203044_at721_B_lymphoblasts30.80034.470Details
BioGPS Gene Atlas203044_atAdipocyte7.55034.470Details
BioGPS Gene Atlas203044_atAdrenalCortex19.55034.470Details
BioGPS Gene Atlas203044_atAdrenalgland22.05034.470Details
BioGPS Gene Atlas203044_atAmygdala9.65034.470Details
BioGPS Gene Atlas203044_atAppendix9.00034.470Details
BioGPS Gene Atlas203044_atAtrioventricularNode7.00034.470Details
BioGPS Gene Atlas203044_atBDCA4+_DentriticCells20.30034.470Details
BioGPS Gene Atlas203044_atBonemarrow16.95034.470Details
BioGPS Gene Atlas203044_atBronchialEpithelialCells11.10034.470Details
BioGPS Gene Atlas203044_atCD105+_Endothelial64.70034.470Details
BioGPS Gene Atlas203044_atCD14+_Monocytes66.45034.470Details
BioGPS Gene Atlas203044_atCD19+_BCells(neg._sel.)22.50034.470Details
BioGPS Gene Atlas203044_atCD33+_Myeloid293.80034.470Details
BioGPS Gene Atlas203044_atCD34+99.20034.470Details
BioGPS Gene Atlas203044_atCD4+_Tcells15.85034.470Details
BioGPS Gene Atlas203044_atCD56+_NKCells109.95034.470Details
BioGPS Gene Atlas203044_atCD71+_EarlyErythroid14.20034.470Details
BioGPS Gene Atlas203044_atCD8+_Tcells26.55034.470Details
BioGPS Gene Atlas203044_atCardiacMyocytes83.70034.470Details
BioGPS Gene Atlas203044_atCaudatenucleus7.25034.470Details
BioGPS Gene Atlas203044_atCerebellum6.60034.470Details
BioGPS Gene Atlas203044_atCerebellumPeduncles9.50034.470Details
BioGPS Gene Atlas203044_atCiliaryGanglion6.50034.470Details
BioGPS Gene Atlas203044_atCingulateCortex9.05034.470Details
BioGPS Gene Atlas203044_atColorectaladenocarcinoma8.65034.470Details
BioGPS Gene Atlas203044_atDorsalRootGanglion7.20034.470Details
BioGPS Gene Atlas203044_atFetalThyroid8.00034.470Details
BioGPS Gene Atlas203044_atFetalbrain8.50034.470Details
BioGPS Gene Atlas203044_atFetalliver7.40034.470Details
BioGPS Gene Atlas203044_atFetallung40.25034.470Details
BioGPS Gene Atlas203044_atGlobusPallidus6.30034.470Details
BioGPS Gene Atlas203044_atHeart8.80034.470Details
BioGPS Gene Atlas203044_atHypothalamus10.70034.470Details
BioGPS Gene Atlas203044_atKidney6.75034.470Details
BioGPS Gene Atlas203044_atLeukemia_chronicMyelogenousK-5628.20034.470Details
BioGPS Gene Atlas203044_atLeukemia_promyelocytic-HL-6013.10034.470Details
BioGPS Gene Atlas203044_atLeukemialymphoblastic(MOLT-4)8.05034.470Details
BioGPS Gene Atlas203044_atLiver10.15034.470Details
BioGPS Gene Atlas203044_atLung10.50034.470Details
BioGPS Gene Atlas203044_atLymphnode11.90034.470Details
BioGPS Gene Atlas203044_atLymphoma_burkitts(Daudi)11.80034.470Details
BioGPS Gene Atlas203044_atLymphoma_burkitts(Raji)12.50034.470Details
BioGPS Gene Atlas203044_atMedullaOblongata7.55034.470Details
BioGPS Gene Atlas203044_atOccipitalLobe6.80034.470Details
BioGPS Gene Atlas203044_atOlfactoryBulb14.15034.470Details
BioGPS Gene Atlas203044_atOvary8.25034.470Details
BioGPS Gene Atlas203044_atPancreas6.75034.470Details
BioGPS Gene Atlas203044_atPancreaticIslet9.20034.470Details
BioGPS Gene Atlas203044_atParietalLobe8.95034.470Details
BioGPS Gene Atlas203044_atPituitary11.75034.470Details
BioGPS Gene Atlas203044_atPlacenta821.70034.470Details
BioGPS Gene Atlas203044_atPons8.00034.470Details
BioGPS Gene Atlas203044_atPrefrontalCortex13.00034.470Details
BioGPS Gene Atlas203044_atProstate16.65034.470Details
BioGPS Gene Atlas203044_atSalivarygland11.15034.470Details
BioGPS Gene Atlas203044_atSkeletalMuscle10.70034.470Details
BioGPS Gene Atlas203044_atSkin7.15034.470Details
BioGPS Gene Atlas203044_atSmoothMuscle139.10034.470Details
BioGPS Gene Atlas203044_atSpinalcord9.80034.470Details
BioGPS Gene Atlas203044_atSubthalamicNucleus8.05034.470Details
BioGPS Gene Atlas203044_atSuperiorCervicalGanglion10.45034.470Details
BioGPS Gene Atlas203044_atTemporalLobe7.70034.470Details
BioGPS Gene Atlas203044_atTestis9.70034.470Details
BioGPS Gene Atlas203044_atTestisGermCell10.50034.470Details
BioGPS Gene Atlas203044_atTestisIntersitial7.50034.470Details
BioGPS Gene Atlas203044_atTestisLeydigCell8.25034.470Details
BioGPS Gene Atlas203044_atTestisSeminiferousTubule8.25034.470Details
BioGPS Gene Atlas203044_atThalamus8.15034.470Details
BioGPS Gene Atlas203044_atThymus9.65034.470Details
BioGPS Gene Atlas203044_atThyroid14.10034.470Details
BioGPS Gene Atlas203044_atTongue8.15034.470Details
BioGPS Gene Atlas203044_atTonsil7.75034.470Details
BioGPS Gene Atlas203044_atTrachea9.55034.470Details
BioGPS Gene Atlas203044_atTrigeminalGanglion9.80034.470Details
BioGPS Gene Atlas203044_atUterus41.65034.470Details
BioGPS Gene Atlas203044_atUterusCorpus8.35034.470Details
BioGPS Gene Atlas203044_atWholeBlood200.20034.470Details
BioGPS Gene Atlas203044_atWholebrain6.25034.470Details
BioGPS Gene Atlas203044_atcolon11.15034.470Details
BioGPS Gene Atlas203044_atpineal_day14.12034.470Details
BioGPS Gene Atlas203044_atpineal_night13.66034.470Details
BioGPS Gene Atlas203044_atretina96.40034.470Details
BioGPS Gene Atlas203044_atsmall_intestine66.40034.470Details
BioGPS NCI60203044_at786889.916790.350Details
BioGPS NCI60203044_atA172768.668790.350Details
BioGPS NCI60203044_atA2041418.848790.350Details
BioGPS NCI60203044_atA361702.272790.350Details
BioGPS NCI60203044_atA498578.430790.350Details
BioGPS NCI60203044_atA549611.924790.350Details
BioGPS NCI60203044_atACC3505.466790.350Details
BioGPS NCI60203044_atACHN308.202790.350Details
BioGPS NCI60203044_atALVA31168.942790.350Details
BioGPS NCI60203044_atCAKI1169.703790.350Details
BioGPS NCI60203044_atCCRT CEM31.625790.350Details
BioGPS NCI60203044_atCOLO205277.151790.350Details
BioGPS NCI60203044_atDLD1227.127790.350Details
BioGPS NCI60203044_atDU145269.555790.350Details
BioGPS NCI60203044_atEKVX747.389790.350Details
BioGPS NCI60203044_atGM1334077.420790.350Details
BioGPS NCI60203044_atGM16003012.428790.350Details
BioGPS NCI60203044_atGM23133750.519790.350Details
BioGPS NCI60203044_atGM23452643.856790.350Details
BioGPS NCI60203044_atGM24931711.019790.350Details
BioGPS NCI60203044_atGM972009.342790.350Details
BioGPS NCI60203044_atHCC2998321.859790.350Details
BioGPS NCI60203044_atHCT116690.027790.350Details
BioGPS NCI60203044_atHCT15614.548790.350Details
BioGPS NCI60203044_atHEK 293 T-rex503.233790.350Details
BioGPS NCI60203044_atHEK 293T743.815790.350Details
BioGPS NCI60203044_atHEK2931530.475790.350Details
BioGPS NCI60203044_atHELA471.018790.350Details
BioGPS NCI60203044_atHEPG2156.226790.350Details
BioGPS NCI60203044_atHL60104.209790.350Details
BioGPS NCI60203044_atHOP62277.391790.350Details
BioGPS NCI60203044_atHOP92809.874790.350Details
BioGPS NCI60203044_atHS578T1236.736790.350Details
BioGPS NCI60203044_atHSG749.254790.350Details
BioGPS NCI60203044_atHT1080330.542790.350Details
BioGPS NCI60203044_atHT29533.689790.350Details
BioGPS NCI60203044_atIGROV1354.920790.350Details
BioGPS NCI60203044_atIOSE80933.141790.350Details
BioGPS NCI60203044_atJURKAT507.779790.350Details
BioGPS NCI60203044_atK562212.630790.350Details
BioGPS NCI60203044_atKM12402.033790.350Details
BioGPS NCI60203044_atLN181059.726790.350Details
BioGPS NCI60203044_atLNCAP664.911790.350Details
BioGPS NCI60203044_atLOX IMVI1061.011790.350Details
BioGPS NCI60203044_atM141572.904790.350Details
BioGPS NCI60203044_atMALME 3M943.497790.350Details
BioGPS NCI60203044_atMCF7481.974790.350Details
BioGPS NCI60203044_atMD MB231255.645790.350Details
BioGPS NCI60203044_atMDA MB435339.333790.350Details
BioGPS NCI60203044_atMOLT4185.981790.350Details
BioGPS NCI60203044_atNCI 460465.122790.350Details
BioGPS NCI60203044_atNCI H226316.890790.350Details
BioGPS NCI60203044_atNCI H23252.496790.350Details
BioGPS NCI60203044_atNCI H322M1057.515790.350Details
BioGPS NCI60203044_atNCVADR RES699.691790.350Details
BioGPS NCI60203044_atOVCAR3676.085790.350Details
BioGPS NCI60203044_atOVCAR4366.939790.350Details
BioGPS NCI60203044_atOVCAR5327.598790.350Details
BioGPS NCI60203044_atOVCAR8265.728790.350Details
BioGPS NCI60203044_atPANC1473.826790.350Details
BioGPS NCI60203044_atRL7244.666790.350Details
BioGPS NCI60203044_atRPMI 82261112.920790.350Details
BioGPS NCI60203044_atRS11846166.713790.350Details
BioGPS NCI60203044_atRXF3931227.212790.350Details
BioGPS NCI60203044_atSAOS22142.674790.350Details
BioGPS NCI60203044_atSF268814.928790.350Details
BioGPS NCI60203044_atSF295551.069790.350Details
BioGPS NCI60203044_atSF5391113.124790.350Details
BioGPS NCI60203044_atSHSYSY+RA1113.690790.350Details
BioGPS NCI60203044_atSHSYSY-RA1651.395790.350Details
BioGPS NCI60203044_atSKMEL2479.343790.350Details
BioGPS NCI60203044_atSKMEL28381.107790.350Details
BioGPS NCI60203044_atSKMEL5419.191790.350Details
BioGPS NCI60203044_atSKOV31001.788790.350Details
BioGPS NCI60203044_atSN12C987.013790.350Details
BioGPS NCI60203044_atSNB191328.209790.350Details
BioGPS NCI60203044_atSNB751190.179790.350Details
BioGPS NCI60203044_atSR2476.151790.350Details
BioGPS NCI60203044_atSW62033.720790.350Details
BioGPS NCI60203044_atT24860.493790.350Details
BioGPS NCI60203044_atT3M4187.817790.350Details
BioGPS NCI60203044_atTK10463.438790.350Details
BioGPS NCI60203044_atU118724.125790.350Details
BioGPS NCI60203044_atU138846.490790.350Details
BioGPS NCI60203044_atU20S296.709790.350Details
BioGPS NCI60203044_atU2512747.278790.350Details
BioGPS NCI60203044_atU87486.010790.350Details
BioGPS NCI60203044_atUACC257960.819790.350Details
BioGPS NCI60203044_atUACC62863.187790.350Details
BioGPS NCI60203044_atUO31530.209790.350Details
BioGPS NCI60203044_atZR75_1167.929790.350Details
BioGPS NCI60203044_atastrocytes748.669790.350Details
BioGPS NCI60203044_athuh-768.966790.350Details

 

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