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Gene ID: 113189 | CHST14 Antibody Resource


CHST14 Antibody Resource
Gene Full Name: 
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
Uniprot: 
Q8NCH0
Protein Name: 
carbohydrate sulfotransferase 14
Nucleotide: 
NM_130468
Alias: 
ATCS;D4ST1;EDSMC1;HNK1ST;
Ensembl: 
ENSG00000169105
Location: 
15q15.1
HPRD: 
16780
NCBI Gene: 
113189
MIM: 
608429

Summary: 
This gene encodes a member of the HNK-1 family of sulfotransferases. The encoded protein transfers sulfate to the C-4 hydroxyl of N-acetylgalactosamine residues in dermatan sulfate. Mutations in this gene have been associated with adducted thumb-clubfoot syndrome.[provided by RefSeq, Mar 2010]
Function: 
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development.
Subcellular location: 
Golgi apparatus membrane; Single-pass type II membrane protein.
PTM: 
Glycoprotein;
Disease: 
Ehlers-Danlos syndrome, musculocontractural type (EDSMC) [MIM:601776]: A form of Ehlers-Danlos syndrome characterized by distinctive craniofacial dysmorphism, congenital contractures of thumbs and fingers, clubfeet, severe kyphoscoliosis, muscular hypotonia, hyperextensible thin skin with easy bruisability and atrophic scarring, wrinkled palms, joint hypermobility, and ocular involvement. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP48994_P050 CHST14 antibody - middle region (ARP48994_P050) Polyclonal Bovine, Dog, Human, Mouse, Rat WB 50ug $289 Details
Polyclonal Antibody ARP48993_P050 CHST14 Antibody (ARP48993_P050) Polyclonal Bovine, Dog, Guinea pig, Human, Mouse, Pig, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB10249 CHST14 antibody - center region (OAAB10249) Mouse WB 400ul $289 Details

Show all CHST14 antibodies


Product Images
CHST14 antibody - middle region (ARP48994_P050) in Human HepG2 cells using Western Blot

Sample Type: Human HepG2

CHST14 antibody - center region (OAAB10249) in Mouse Stomach cells using Western Blot

Sample Type: Mouse Stomach


CHST14 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP48994 Bovine CHST14 antibody; Bos taurus CHST14 antibody A3KMX1 100.0%
ARP48993 Bovine CHST14 antibody; Bos taurus CHST14 antibody A3KMX1 93.0%
ARP48993 Cat CHST14 antibody; Felis catus CHST14 antibody M3W2U1 100.0%
ARP48994 Cat CHST14 antibody; Felis catus CHST14 antibody M3W2U1 100.0%
ARP48993 Chicken CHST14 antibody; Gallus gallus CHST14 antibody R4GH42 79.0%
ARP48993 Chimpanzee CHST14 antibody; Pan troglodytes CHST14 antibody H2Q964 100.0%
ARP48994 Chimpanzee CHST14 antibody; Pan troglodytes CHST14 antibody H2Q964 100.0%
ARP48993 Dog CHST14 antibody; Canis familiaris CHST14 antibody J9P9Z8 100.0%
ARP48994 Dog CHST14 antibody; Canis familiaris CHST14 antibody J9P9Z8 100.0%
ARP48993 Dog CHST14 antibody; Canis familiaris CHST14 antibody F1PKB8 100.0%
ARP48994 Dog CHST14 antibody; Canis familiaris CHST14 antibody F1PKB8 100.0%
ARP48993 European domestic ferret CHST14 antibody; Mustela putorius furo CHST14 antibody M3Z800 100.0%
ARP48994 European domestic ferret CHST14 antibody; Mustela putorius furo CHST14 antibody M3Z800 100.0%
ARP48993 Giant panda CHST14 antibody; Ailuropoda melanoleuca CHST14 antibody G1MLH6 100.0%
ARP48994 Giant panda CHST14 antibody; Ailuropoda melanoleuca CHST14 antibody G1MLH6 100.0%
ARP48993 Human CHST14 antibody; Homo sapiens CHST14 antibody H0YN65 100.0%
ARP48994 Human CHST14 antibody; Homo sapiens CHST14 antibody H0YN65 100.0%
ARP48993 Human CHST14 antibody; Homo sapiens CHST14 antibody Q8NCH0 100.0%
ARP48994 Human CHST14 antibody; Homo sapiens CHST14 antibody Q8NCH0 100.0%
ARP48993 Mouse CHST14 antibody; Mus musculus CHST14 antibody Q3U2T1 100.0%
ARP48994 Mouse CHST14 antibody; Mus musculus CHST14 antibody Q3U2T1 100.0%
ARP48993 Mouse CHST14 antibody; Mus musculus CHST14 antibody Q3U3W1 100.0%
ARP48994 Mouse CHST14 antibody; Mus musculus CHST14 antibody Q3U3W1 100.0%
ARP48993 Mouse CHST14 antibody; Mus musculus CHST14 antibody Q80V53 100.0%
ARP48994 Mouse CHST14 antibody; Mus musculus CHST14 antibody Q80V53 100.0%
ARP48993 Mouse CHST14 antibody; Mus musculus CHST14 antibody A2AQV2 100.0%
ARP48994 Mouse CHST14 antibody; Mus musculus CHST14 antibody A2AQV2 100.0%
ARP48993 Pig CHST14 antibody; Sus scrofa CHST14 antibody F1SSR7 100.0%
ARP48994 Pig CHST14 antibody; Sus scrofa CHST14 antibody F1SSR7 100.0%
ARP48993 Rat CHST14 antibody; Rattus norvegicus CHST14 antibody B2GV63 100.0%
ARP48994 Rat CHST14 antibody; Rattus norvegicus CHST14 antibody B2GV63 100.0%
ARP48993 Rhesus macaque CHST14 antibody; Macaca mulatta CHST14 antibody H9F8X7 100.0%
ARP48994 Rhesus macaque CHST14 antibody; Macaca mulatta CHST14 antibody H9F8X7 100.0%
ARP48993 Rhesus macaque CHST14 antibody; Macaca mulatta CHST14 antibody F7GZ21 100.0%
ARP48994 Rhesus macaque CHST14 antibody; Macaca mulatta CHST14 antibody F7GZ21 100.0%
ARP48994 Small-eared galago CHST14 antibody; Otolemur garnettii CHST14 antibody H0XJT2 100.0%
ARP48993 Small-eared galago CHST14 antibody; Otolemur garnettii CHST14 antibody H0XJT2 93.0%
ARP48993 Sumatran orangutan CHST14 antibody; Pongo abelii CHST14 antibody H2NMU5 100.0%
ARP48994 Sumatran orangutan CHST14 antibody; Pongo abelii CHST14 antibody H2NMU5 100.0%
ARP48993 Tasmanian devil CHST14 antibody; Sarcophilus harrisii CHST14 antibody G3WNT5 100.0%
ARP48994 Tasmanian devil CHST14 antibody; Sarcophilus harrisii CHST14 antibody G3WNT5 100.0%
ARP48993 Thirteen-lined ground squirrel CHST14 antibody; Spermophilus tridecemlineatus CHST14 antibody I3NGR0 100.0%
ARP48994 Thirteen-lined ground squirrel CHST14 antibody; Spermophilus tridecemlineatus CHST14 antibody I3NGR0 100.0%
ARP48993 Western clawed frog CHST14 antibody; Xenopus tropicalis CHST14 antibody F6W9F5 86.0%
ARP48993 White-tufted-ear marmoset CHST14 antibody; Callithrix jacchus CHST14 antibody F7FE82 100.0%
ARP48994 White-tufted-ear marmoset CHST14 antibody; Callithrix jacchus CHST14 antibody F7FE82 100.0%

Tissue & Cell Line Gene Expression Data