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Gene ID: 1146 | CHRNG Antibody Resource


CHRNG Antibody Resource
Gene Full Name: 
cholinergic receptor, nicotinic, gamma (muscle)
Uniprot: 
P07510
Protein Name: 
acetylcholine receptor subunit gamma
Nucleotide: 
XM_005246261
Alias: 
ACHRG;
Ensembl: 
ENSG00000196811
Location: 
2q37.1
HPRD: 
00009
NCBI Gene: 
1146
MIM: 
100730

Summary: 
The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.[provided by RefSeq, Sep 2009]
Function: 
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular location: 
Cell junction › synapse › postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
PTM: 
Disulfide bond;
Disease: 
Multiple pterygium syndrome, lethal type (LMPS) [MIM:253290]: Multiple pterygia are found infrequently in children with arthrogryposis and in fetuses with fetal akinesia syndrome. In lethal multiple pterygium syndrome there is intrauterine growth retardation, multiple pterygia, and flexion contractures causing severe arthrogryposis and fetal akinesia. Subcutaneous edema can be severe, causing fetal hydrops with cystic hygroma and lung hypoplasia. Oligohydramnios and facial anomalies are frequent. Note: The disease is caused by mutations affecting the gene represented in this entry. Multiple pterygium syndrome, Escobar variant (EVMPS) [MIM:265000]: Non-lethal form of arthrogryposis multiplex congenita. It is an autosomal recessive condition characterized by excessive webbing (pterygia), congenital contractures (arthrogryposis), and scoliosis. Variable other features include intrauterine death, congenital respiratory distress, short stature, faciocranial dysmorphism, ptosis, low-set ears, arachnodactyly and cryptorchism in males. Congenital contractures are common and may be caused by reduced fetal movements at sensitive times of development. Possible causes of decreased fetal mobility include space constraints such as oligohydramnion, drugs, metabolic conditions or neuromuscular disorders including myasthenia gravis. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody AVARP13024_P050 CHRNG antibody - N-terminal region (AVARP13024_P050) Polyclonal Bovine, Dog, Guinea pig, Human, Mouse, Rabbit, Rat WB 50ug $289 Details
Monoclonal Antibody OASA00887 CHRNG Antibody (OASA00887) Human IHC-AFF, FC, IP, WB 0.5ml $400 Details
Polyclonal Antibody ARP30681_P050 CHRNG Antibody (ARP30681_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB12524 CHRNG antibody - N - terminal region (OAAB12524) Human WB 400ul $289 Details

Show all CHRNG antibodies


Product Images
CHRNG antibody - N-terminal region (AVARP13024_P050) in Human MCF-7 cells using Western Blot

Sample Type: Human MCF-7

CHRNG antibody - N - terminal region (OAAB12524) in CEM cells using Western Blot

Sample Type: CEM


CHRNG Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP30681 Bovine CHRNG antibody; Bos taurus CHRNG antibody P13536 79.0%
ARP30681 Cat CHRNG antibody; Felis catus CHRNG antibody M3W4I0 93.0%
ARP34975 Chicken CHRNG antibody; Gallus gallus CHRNG antibody P02713 85.0%
ARP34975 Chicken CHRNG antibody; Gallus gallus CHRNG antibody F1NJ22 85.0%
ARP30681 Chimpanzee CHRNG antibody; Pan troglodytes CHRNG antibody H2R3V0 100.0%
ARP30679 Chinese softshell turtle CHRNG antibody; Pelodiscus sinensis CHRNG antibody K7FXG2 80.0%
ARP34975 Chinese softshell turtle CHRNG antibody; Pelodiscus sinensis CHRNG antibody K7FXG2 79.0%
ARP34975 Collared flycatcher CHRNG antibody; Ficedula albicollis CHRNG antibody U3JZ73 85.0%
ARP30681 Dog CHRNG antibody; Canis familiaris CHRNG antibody E2R2W1 79.0%
ARP30681 Dog CHRNG antibody; Canis familiaris CHRNG antibody F6XNB0 79.0%
ARP34975 Domestic duck CHRNG antibody; Anas platyrhynchos CHRNG antibody U3J784 93.0%
ARP30681 European domestic ferret CHRNG antibody; Mustela putorius furo CHRNG antibody M3Y1G2 86.0%
ARP30681 Giant panda CHRNG antibody; Ailuropoda melanoleuca CHRNG antibody G1MDK7 93.0%
ARP30681 Horse CHRNG antibody; Equus caballus CHRNG antibody F7AHA1 86.0%
ARP30681 Human CHRNG antibody; Homo sapiens CHRNG antibody P07510 100.0%
ARP30681 Human CHRNG antibody; Homo sapiens CHRNG antibody Q14DU4 100.0%
ARP30681 Human CHRNG antibody; Homo sapiens CHRNG antibody H7BYH0 100.0%
ARP30681 Mouse CHRNG antibody; Mus musculus CHRNG antibody H8YHW6 93.0%
ARP30681 Mouse CHRNG antibody; Mus musculus CHRNG antibody I0B501 93.0%
ARP30681 Mouse CHRNG antibody; Mus musculus CHRNG antibody I0B502 93.0%
ARP30681 Mouse CHRNG antibody; Mus musculus CHRNG antibody P04760-2 93.0%
ARP30681 Mouse CHRNG antibody; Mus musculus CHRNG antibody P04760 93.0%
ARP30681 Mouse CHRNG antibody; Mus musculus CHRNG antibody F8VQK4 93.0%
ARP30681 Northern white-cheeked gibbon CHRNG antibody; Nomascus leucogenys CHRNG antibody G1RVX5 93.0%
ARP30681 Pig CHRNG antibody; Sus scrofa CHRNG antibody F1SMT2 79.0%
ARP30681 Rabbit CHRNG antibody; Oryctolagus cuniculus CHRNG antibody G1U1B7 86.0%
ARP30681 Rat CHRNG antibody; Rattus norvegicus CHRNG antibody P18916 93.0%
ARP30681 Rat CHRNG antibody; Rattus norvegicus CHRNG antibody G3V8K1 93.0%
ARP30681 Rhesus macaque CHRNG antibody; Macaca mulatta CHRNG antibody F7H3A2 100.0%
ARP30681 Small-eared galago CHRNG antibody; Otolemur garnettii CHRNG antibody H0Y1Y4 86.0%
ARP34975 Tasmanian devil CHRNG antibody; Sarcophilus harrisii CHRNG antibody G3WIB9 93.0%
ARP30681 Thirteen-lined ground squirrel CHRNG antibody; Spermophilus tridecemlineatus CHRNG antibody I3M2D5 93.0%
ARP30681 White-tufted-ear marmoset CHRNG antibody; Callithrix jacchus CHRNG antibody F7BI57 100.0%
ARP30681 White-tufted-ear marmoset CHRNG antibody; Callithrix jacchus CHRNG antibody F7BIV8 100.0%
ARP34975 Zebra finch CHRNG antibody; Taeniopygia guttata CHRNG antibody H0ZI49 85.0%
ARP34975 Zebrafish CHRNG antibody; Danio rerio CHRNG antibody E7F9V1 85.0%
ARP34975 Zebrafish CHRNG antibody; Danio rerio CHRNG antibody G1FMP9 85.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas221355_at721_B_lymphoblasts10.9509.900Details
BioGPS Gene Atlas221355_atAdipocyte9.2009.900Details
BioGPS Gene Atlas221355_atAdrenalCortex9.9509.900Details
BioGPS Gene Atlas221355_atAdrenalgland7.8509.900Details
BioGPS Gene Atlas221355_atAmygdala9.7009.900Details
BioGPS Gene Atlas221355_atAppendix11.9009.900Details
BioGPS Gene Atlas221355_atAtrioventricularNode10.4009.900Details
BioGPS Gene Atlas221355_atBDCA4+_DentriticCells10.0509.900Details
BioGPS Gene Atlas221355_atBonemarrow12.5009.900Details
BioGPS Gene Atlas221355_atBronchialEpithelialCells8.7509.900Details
BioGPS Gene Atlas221355_atCD105+_Endothelial10.1009.900Details
BioGPS Gene Atlas221355_atCD14+_Monocytes10.2509.900Details
BioGPS Gene Atlas221355_atCD19+_BCells(neg._sel.)11.7009.900Details
BioGPS Gene Atlas221355_atCD33+_Myeloid12.3009.900Details
BioGPS Gene Atlas221355_atCD34+13.3509.900Details
BioGPS Gene Atlas221355_atCD4+_Tcells9.9009.900Details
BioGPS Gene Atlas221355_atCD56+_NKCells10.9509.900Details
BioGPS Gene Atlas221355_atCD71+_EarlyErythroid14.2509.900Details
BioGPS Gene Atlas221355_atCD8+_Tcells8.9509.900Details
BioGPS Gene Atlas221355_atCardiacMyocytes22.1509.900Details
BioGPS Gene Atlas221355_atCaudatenucleus8.0509.900Details
BioGPS Gene Atlas221355_atCerebellum7.5009.900Details
BioGPS Gene Atlas221355_atCerebellumPeduncles10.1509.900Details
BioGPS Gene Atlas221355_atCiliaryGanglion7.9509.900Details
BioGPS Gene Atlas221355_atCingulateCortex10.2009.900Details
BioGPS Gene Atlas221355_atColorectaladenocarcinoma9.3509.900Details
BioGPS Gene Atlas221355_atDorsalRootGanglion8.1009.900Details
BioGPS Gene Atlas221355_atFetalThyroid9.7009.900Details
BioGPS Gene Atlas221355_atFetalbrain10.0509.900Details
BioGPS Gene Atlas221355_atFetalliver7.8009.900Details
BioGPS Gene Atlas221355_atFetallung7.5009.900Details
BioGPS Gene Atlas221355_atGlobusPallidus6.7009.900Details
BioGPS Gene Atlas221355_atHeart13.5509.900Details
BioGPS Gene Atlas221355_atHypothalamus9.5509.900Details
BioGPS Gene Atlas221355_atKidney7.4509.900Details
BioGPS Gene Atlas221355_atLeukemia_chronicMyelogenousK-5629.0509.900Details
BioGPS Gene Atlas221355_atLeukemia_promyelocytic-HL-608.2509.900Details
BioGPS Gene Atlas221355_atLeukemialymphoblastic(MOLT-4)7.7509.900Details
BioGPS Gene Atlas221355_atLiver15.7009.900Details
BioGPS Gene Atlas221355_atLung13.9509.900Details
BioGPS Gene Atlas221355_atLymphnode7.8509.900Details
BioGPS Gene Atlas221355_atLymphoma_burkitts(Daudi)11.8509.900Details
BioGPS Gene Atlas221355_atLymphoma_burkitts(Raji)14.5509.900Details
BioGPS Gene Atlas221355_atMedullaOblongata8.0509.900Details
BioGPS Gene Atlas221355_atOccipitalLobe7.8509.900Details
BioGPS Gene Atlas221355_atOlfactoryBulb7.3509.900Details
BioGPS Gene Atlas221355_atOvary7.7009.900Details
BioGPS Gene Atlas221355_atPancreas7.6509.900Details
BioGPS Gene Atlas221355_atPancreaticIslet10.4009.900Details
BioGPS Gene Atlas221355_atParietalLobe9.9509.900Details
BioGPS Gene Atlas221355_atPituitary10.7509.900Details
BioGPS Gene Atlas221355_atPlacenta9.1009.900Details
BioGPS Gene Atlas221355_atPons8.5509.900Details
BioGPS Gene Atlas221355_atPrefrontalCortex11.4009.900Details
BioGPS Gene Atlas221355_atProstate10.8509.900Details
BioGPS Gene Atlas221355_atSalivarygland7.5509.900Details
BioGPS Gene Atlas221355_atSkeletalMuscle12.9009.900Details
BioGPS Gene Atlas221355_atSkin9.8509.900Details
BioGPS Gene Atlas221355_atSmoothMuscle10.4509.900Details
BioGPS Gene Atlas221355_atSpinalcord9.6509.900Details
BioGPS Gene Atlas221355_atSubthalamicNucleus8.5509.900Details
BioGPS Gene Atlas221355_atSuperiorCervicalGanglion10.7009.900Details
BioGPS Gene Atlas221355_atTemporalLobe8.5509.900Details
BioGPS Gene Atlas221355_atTestis8.0509.900Details
BioGPS Gene Atlas221355_atTestisGermCell7.6009.900Details
BioGPS Gene Atlas221355_atTestisIntersitial7.6509.900Details
BioGPS Gene Atlas221355_atTestisLeydigCell9.4509.900Details
BioGPS Gene Atlas221355_atTestisSeminiferousTubule8.0009.900Details
BioGPS Gene Atlas221355_atThalamus9.2009.900Details
BioGPS Gene Atlas221355_atThymus7.3509.900Details
BioGPS Gene Atlas221355_atThyroid11.6509.900Details
BioGPS Gene Atlas221355_atTongue10.6509.900Details
BioGPS Gene Atlas221355_atTonsil9.7009.900Details
BioGPS Gene Atlas221355_atTrachea7.6509.900Details
BioGPS Gene Atlas221355_atTrigeminalGanglion9.3509.900Details
BioGPS Gene Atlas221355_atUterus7.3009.900Details
BioGPS Gene Atlas221355_atUterusCorpus8.3009.900Details
BioGPS Gene Atlas221355_atWholeBlood11.3009.900Details
BioGPS Gene Atlas221355_atWholebrain7.6509.900Details
BioGPS Gene Atlas221355_atcolon9.3009.900Details
BioGPS Gene Atlas221355_atpineal_day10.8409.900Details
BioGPS Gene Atlas221355_atpineal_night10.7609.900Details
BioGPS Gene Atlas221355_atretina11.1759.900Details
BioGPS Gene Atlas221355_atsmall_intestine9.0009.900Details
BioGPS NCI60221355_at78610.1559.770Details
BioGPS NCI60221355_atA1728.4469.770Details
BioGPS NCI60221355_atA2049.1249.770Details
BioGPS NCI60221355_atA3619.1489.770Details
BioGPS NCI60221355_atA4988.9269.770Details
BioGPS NCI60221355_atA5499.1269.770Details
BioGPS NCI60221355_atACC39.4509.770Details
BioGPS NCI60221355_atACHN7.4089.770Details
BioGPS NCI60221355_atALVA3115.4289.770Details
BioGPS NCI60221355_atCAKI19.3709.770Details
BioGPS NCI60221355_atCCRT CEM10.3369.770Details
BioGPS NCI60221355_atCOLO2059.0749.770Details
BioGPS NCI60221355_atDLD18.7239.770Details
BioGPS NCI60221355_atDU1458.7969.770Details
BioGPS NCI60221355_atEKVX8.3189.770Details
BioGPS NCI60221355_atGM13310.1499.770Details
BioGPS NCI60221355_atGM160011.6139.770Details
BioGPS NCI60221355_atGM23139.0849.770Details
BioGPS NCI60221355_atGM234510.4439.770Details
BioGPS NCI60221355_atGM24939.4199.770Details
BioGPS NCI60221355_atGM9713.4059.770Details
BioGPS NCI60221355_atHCC29988.0489.770Details
BioGPS NCI60221355_atHCT1168.9419.770Details
BioGPS NCI60221355_atHCT158.2909.770Details
BioGPS NCI60221355_atHEK 293 T-rex30.7979.770Details
BioGPS NCI60221355_atHEK 293T8.8309.770Details
BioGPS NCI60221355_atHEK2939.3129.770Details
BioGPS NCI60221355_atHELA5.2619.770Details
BioGPS NCI60221355_atHEPG27.5029.770Details
BioGPS NCI60221355_atHL6011.0079.770Details
BioGPS NCI60221355_atHOP628.9369.770Details
BioGPS NCI60221355_atHOP928.5809.770Details
BioGPS NCI60221355_atHS578T6.6319.770Details
BioGPS NCI60221355_atHSG5.1739.770Details
BioGPS NCI60221355_atHT10806.7769.770Details
BioGPS NCI60221355_atHT2914.1579.770Details
BioGPS NCI60221355_atIGROV19.0159.770Details
BioGPS NCI60221355_atIOSE804.7759.770Details
BioGPS NCI60221355_atJURKAT9.0259.770Details
BioGPS NCI60221355_atK56211.3369.770Details
BioGPS NCI60221355_atKM129.4179.770Details
BioGPS NCI60221355_atLN188.4619.770Details
BioGPS NCI60221355_atLNCAP9.8159.770Details
BioGPS NCI60221355_atLOX IMVI10.8819.770Details
BioGPS NCI60221355_atM148.7779.770Details
BioGPS NCI60221355_atMALME 3M9.8779.770Details
BioGPS NCI60221355_atMCF78.5279.770Details
BioGPS NCI60221355_atMD MB23110.3129.770Details
BioGPS NCI60221355_atMDA MB4359.7709.770Details
BioGPS NCI60221355_atMOLT417.3689.770Details
BioGPS NCI60221355_atNCI 4609.9649.770Details
BioGPS NCI60221355_atNCI H2269.5249.770Details
BioGPS NCI60221355_atNCI H239.4579.770Details
BioGPS NCI60221355_atNCI H322M8.8959.770Details
BioGPS NCI60221355_atNCVADR RES8.2429.770Details
BioGPS NCI60221355_atOVCAR39.4409.770Details
BioGPS NCI60221355_atOVCAR48.8509.770Details
BioGPS NCI60221355_atOVCAR58.6689.770Details
BioGPS NCI60221355_atOVCAR87.9439.770Details
BioGPS NCI60221355_atPANC19.1699.770Details
BioGPS NCI60221355_atRL79.1329.770Details
BioGPS NCI60221355_atRPMI 822610.3439.770Details
BioGPS NCI60221355_atRS1184611.8629.770Details
BioGPS NCI60221355_atRXF3938.8739.770Details
BioGPS NCI60221355_atSAOS213.7739.770Details
BioGPS NCI60221355_atSF26810.3109.770Details
BioGPS NCI60221355_atSF2958.7849.770Details
BioGPS NCI60221355_atSF5398.7509.770Details
BioGPS NCI60221355_atSHSYSY+RA8.4819.770Details
BioGPS NCI60221355_atSHSYSY-RA8.8309.770Details
BioGPS NCI60221355_atSKMEL24.4409.770Details
BioGPS NCI60221355_atSKMEL289.2469.770Details
BioGPS NCI60221355_atSKMEL58.8969.770Details
BioGPS NCI60221355_atSKOV39.2879.770Details
BioGPS NCI60221355_atSN12C8.8329.770Details
BioGPS NCI60221355_atSNB197.6559.770Details
BioGPS NCI60221355_atSNB759.0599.770Details
BioGPS NCI60221355_atSR11.1449.770Details
BioGPS NCI60221355_atSW62012.2469.770Details
BioGPS NCI60221355_atT2410.1309.770Details
BioGPS NCI60221355_atT3M415.7299.770Details
BioGPS NCI60221355_atTK108.9369.770Details
BioGPS NCI60221355_atU1188.8389.770Details
BioGPS NCI60221355_atU1388.4159.770Details
BioGPS NCI60221355_atU20S9.6799.770Details
BioGPS NCI60221355_atU2518.8059.770Details
BioGPS NCI60221355_atU878.7429.770Details
BioGPS NCI60221355_atUACC2578.9719.770Details
BioGPS NCI60221355_atUACC629.0529.770Details
BioGPS NCI60221355_atUO318.0849.770Details
BioGPS NCI60221355_atZR75_18.0429.770Details
BioGPS NCI60221355_atastrocytes9.0979.770Details
BioGPS NCI60221355_athuh-710.6939.770Details