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Gene ID: 1140 | CHRNB1 Antibody Resource


CHRNB1 Antibody Resource
Gene Full Name: 
cholinergic receptor, nicotinic, beta 1 (muscle)
Uniprot: 
P11230
Protein Name: 
acetylcholine receptor subunit beta
Nucleotide: 
NM_000747
Alias: 
ACHRB;CHRNB;CMS1D;CMS2A;SCCMS;
Ensembl: 
ENSG00000170175
Location: 
17p13.1
HPRD: 
01156
NCBI Gene: 
1140
MIM: 
100710

Summary: 
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008]
Function: 
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular location: 
Cell junction › synapse › postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
PTM: 
Disulfide bond;
Disease: 
Myasthenic syndrome, congenital, slow-channel (SCCMS) [MIM:601462]: A common congenital myasthenic syndrome. Congenital myasthenic syndromes are characterized by muscle weakness affecting the axial and limb muscles (with hypotonia in early-onset forms), the ocular muscles (leading to ptosis and ophthalmoplegia), and the facial and bulbar musculature (affecting sucking and swallowing, and leading to dysphonia). The symptoms fluctuate and worsen with physical effort. Congenital myasthenic syndrome slow-channel type is caused by kinetic abnormalities of the AChR, resulting in prolonged endplate currents and prolonged AChR channel opening episodes. Note: The disease is caused by mutations affecting the gene represented in this entry. Myasthenic syndrome, congenital, associated with acetylcholine receptor deficiency (CMS-ACHRD) [MIM:608931]: A post-synaptic congenital myasthenic syndrome. Congenital myasthenic syndromes (CMS) are inherited disorders of neuromuscular transmission that stem from mutations in presynaptic, synaptic, or postsynaptic proteins. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Monoclonal Antibody OASA00886 CHRNB1 Antibody (OASA00886) Human IHC-AFF, FC, IP, WB 0.5ml $390 Details
Polyclonal Antibody OAEB01105 Goat Anti-CHRNB1 / ACHRB Antibody (OAEB01105) Dog, Horse, Human, Mouse, Rabbit WB 0.1mg $289 Details
Polyclonal Antibody ARP30676_P050 CHRNB1 Antibody (ARP30676_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP34969_P050 CHRNB1 Antibody (ARP34969_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Pig, Rabbit Not tested 50 ug $125 Details
Polyclonal Antibody OAAF03217 CHRNB1 Antibody (OAAF03217) Polyclonal Human, Mouse, Rat WB, ELISA 100 ug $229 Details

Show all CHRNB1 antibodies


Product Images
CHRNB1 Antibody (OAAF03217) in HeLa cells using Western Blot

Sample Type: HeLa

Goat Anti-CHRNB1 / ACHRB Antibody (OAEB01105) in Human Cerebellum cells using Western Blot

Sample Type: Human Cerebellum


CHRNB1 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP34969 Bovine CHRNB1 antibody; Bos taurus CHRNB1 antibody P04758 100.0%
ARP30676 Bovine CHRNB1 antibody; Bos taurus CHRNB1 antibody P04758 93.0%
ARP30676 Cat CHRNB1 antibody; Felis catus CHRNB1 antibody M3WBR6 100.0%
ARP34969 Cat CHRNB1 antibody; Felis catus CHRNB1 antibody M3WBR6 93.0%
ARP30676 Chimpanzee CHRNB1 antibody; Pan troglodytes CHRNB1 antibody K7C899 100.0%
ARP34969 Chimpanzee CHRNB1 antibody; Pan troglodytes CHRNB1 antibody K7C899 100.0%
ARP30676 Chimpanzee CHRNB1 antibody; Pan troglodytes CHRNB1 antibody H2QC41 100.0%
ARP34969 Chimpanzee CHRNB1 antibody; Pan troglodytes CHRNB1 antibody H2QC41 100.0%
ARP30676 Dog CHRNB1 antibody; Canis familiaris CHRNB1 antibody E2QZ91 93.0%
ARP30676 Dog CHRNB1 antibody; Canis familiaris CHRNB1 antibody F6XTV7 93.0%
ARP34969 Dog CHRNB1 antibody; Canis familiaris CHRNB1 antibody E2QZ91 85.0%
ARP34969 Dog CHRNB1 antibody; Canis familiaris CHRNB1 antibody F6XTV7 85.0%
ARP30676 European domestic ferret CHRNB1 antibody; Mustela putorius furo CHRNB1 antibody M3YE46 100.0%
ARP34969 European domestic ferret CHRNB1 antibody; Mustela putorius furo CHRNB1 antibody M3YE46 87.0%
ARP30676 Gray short-tailed opossum CHRNB1 antibody; Monodelphis domestica CHRNB1 antibody F6RFH4 79.0%
ARP30676 Horse CHRNB1 antibody; Equus caballus CHRNB1 antibody F6SLE5 100.0%
ARP34969 Horse CHRNB1 antibody; Equus caballus CHRNB1 antibody F6SLE5 100.0%
ARP30676 Human CHRNB1 antibody; Homo sapiens CHRNB1 antibody P11230 100.0%
ARP34969 Human CHRNB1 antibody; Homo sapiens CHRNB1 antibody P11230 100.0%
ARP30676 Human CHRNB1 antibody; Homo sapiens CHRNB1 antibody Q8IZ46 100.0%
ARP30676 Human CHRNB1 antibody; Homo sapiens CHRNB1 antibody I3L3Q9 100.0%
ARP30676 Human CHRNB1 antibody; Homo sapiens CHRNB1 antibody I3L4N5 100.0%
ARP34969 Human CHRNB1 antibody; Homo sapiens CHRNB1 antibody I3L4N5 100.0%
ARP34969 Human CHRNB1 antibody; Homo sapiens CHRNB1 antibody Q8IZ46 93.0%
ARP30676 Mouse CHRNB1 antibody; Mus musculus CHRNB1 antibody P09690 100.0%
ARP30676 Mouse CHRNB1 antibody; Mus musculus CHRNB1 antibody Q8CG00 100.0%
ARP30676 Pig CHRNB1 antibody; Sus scrofa CHRNB1 antibody I3L9G3 100.0%
ARP34969 Pig CHRNB1 antibody; Sus scrofa CHRNB1 antibody I3L9G3 93.0%
ARP34969 Rabbit CHRNB1 antibody; Oryctolagus cuniculus CHRNB1 antibody G1ST18 100.0%
ARP30676 Rabbit CHRNB1 antibody; Oryctolagus cuniculus CHRNB1 antibody G1ST18 93.0%
ARP30676 Rat CHRNB1 antibody; Rattus norvegicus CHRNB1 antibody P25109 93.0%
ARP30676 Small-eared galago CHRNB1 antibody; Otolemur garnettii CHRNB1 antibody H0WKK8 100.0%
ARP34969 Small-eared galago CHRNB1 antibody; Otolemur garnettii CHRNB1 antibody H0WKK8 86.0%
ARP30676 Sumatran orangutan CHRNB1 antibody; Pongo abelii CHRNB1 antibody H2NSJ7 100.0%
ARP34969 Sumatran orangutan CHRNB1 antibody; Pongo abelii CHRNB1 antibody H2NSJ7 100.0%
ARP30676 Tasmanian devil CHRNB1 antibody; Sarcophilus harrisii CHRNB1 antibody G3W5B4 86.0%
ARP34969 Thirteen-lined ground squirrel CHRNB1 antibody; Spermophilus tridecemlineatus CHRNB1 antibody I3LWF2 93.0%
ARP30676 Thirteen-lined ground squirrel CHRNB1 antibody; Spermophilus tridecemlineatus CHRNB1 antibody I3LWF2 79.0%
ARP30676 White-tufted-ear marmoset CHRNB1 antibody; Callithrix jacchus CHRNB1 antibody U3DF34 100.0%
ARP34969 White-tufted-ear marmoset CHRNB1 antibody; Callithrix jacchus CHRNB1 antibody U3DF34 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas206703_at721_B_lymphoblasts5.7504.830Details
BioGPS Gene Atlas206703_atAdipocyte4.6004.830Details
BioGPS Gene Atlas206703_atAdrenalCortex5.2504.830Details
BioGPS Gene Atlas206703_atAdrenalgland4.6504.830Details
BioGPS Gene Atlas206703_atAmygdala4.9004.830Details
BioGPS Gene Atlas206703_atAppendix4.7504.830Details
BioGPS Gene Atlas206703_atAtrioventricularNode4.1004.830Details
BioGPS Gene Atlas206703_atBDCA4+_DentriticCells5.1004.830Details
BioGPS Gene Atlas206703_atBonemarrow4.5504.830Details
BioGPS Gene Atlas206703_atBronchialEpithelialCells5.6004.830Details
BioGPS Gene Atlas206703_atCD105+_Endothelial4.5004.830Details
BioGPS Gene Atlas206703_atCD14+_Monocytes4.8004.830Details
BioGPS Gene Atlas206703_atCD19+_BCells(neg._sel.)4.9004.830Details
BioGPS Gene Atlas206703_atCD33+_Myeloid5.6504.830Details
BioGPS Gene Atlas206703_atCD34+5.9004.830Details
BioGPS Gene Atlas206703_atCD4+_Tcells4.8504.830Details
BioGPS Gene Atlas206703_atCD56+_NKCells5.3004.830Details
BioGPS Gene Atlas206703_atCD71+_EarlyErythroid4.2004.830Details
BioGPS Gene Atlas206703_atCD8+_Tcells4.3504.830Details
BioGPS Gene Atlas206703_atCardiacMyocytes5.8004.830Details
BioGPS Gene Atlas206703_atCaudatenucleus4.1004.830Details
BioGPS Gene Atlas206703_atCerebellum3.8504.830Details
BioGPS Gene Atlas206703_atCerebellumPeduncles5.6504.830Details
BioGPS Gene Atlas206703_atCiliaryGanglion3.2004.830Details
BioGPS Gene Atlas206703_atCingulateCortex4.7504.830Details
BioGPS Gene Atlas206703_atColorectaladenocarcinoma4.7004.830Details
BioGPS Gene Atlas206703_atDorsalRootGanglion3.5504.830Details
BioGPS Gene Atlas206703_atFetalThyroid4.5004.830Details
BioGPS Gene Atlas206703_atFetalbrain4.6504.830Details
BioGPS Gene Atlas206703_atFetalliver3.9504.830Details
BioGPS Gene Atlas206703_atFetallung3.8004.830Details
BioGPS Gene Atlas206703_atGlobusPallidus3.3504.830Details
BioGPS Gene Atlas206703_atHeart12.6504.830Details
BioGPS Gene Atlas206703_atHypothalamus5.0504.830Details
BioGPS Gene Atlas206703_atKidney4.1004.830Details
BioGPS Gene Atlas206703_atLeukemia_chronicMyelogenousK-5624.1504.830Details
BioGPS Gene Atlas206703_atLeukemia_promyelocytic-HL-604.0504.830Details
BioGPS Gene Atlas206703_atLeukemialymphoblastic(MOLT-4)4.3004.830Details
BioGPS Gene Atlas206703_atLiver6.6004.830Details
BioGPS Gene Atlas206703_atLung5.1004.830Details
BioGPS Gene Atlas206703_atLymphnode4.0504.830Details
BioGPS Gene Atlas206703_atLymphoma_burkitts(Daudi)5.9504.830Details
BioGPS Gene Atlas206703_atLymphoma_burkitts(Raji)6.3004.830Details
BioGPS Gene Atlas206703_atMedullaOblongata4.3504.830Details
BioGPS Gene Atlas206703_atOccipitalLobe4.1004.830Details
BioGPS Gene Atlas206703_atOlfactoryBulb3.6004.830Details
BioGPS Gene Atlas206703_atOvary3.1004.830Details
BioGPS Gene Atlas206703_atPancreas3.7504.830Details
BioGPS Gene Atlas206703_atPancreaticIslet4.9504.830Details
BioGPS Gene Atlas206703_atParietalLobe4.8504.830Details
BioGPS Gene Atlas206703_atPituitary5.3504.830Details
BioGPS Gene Atlas206703_atPlacenta4.6004.830Details
BioGPS Gene Atlas206703_atPons4.6004.830Details
BioGPS Gene Atlas206703_atPrefrontalCortex5.6504.830Details
BioGPS Gene Atlas206703_atProstate5.4504.830Details
BioGPS Gene Atlas206703_atSalivarygland3.7004.830Details
BioGPS Gene Atlas206703_atSkeletalMuscle9.6504.830Details
BioGPS Gene Atlas206703_atSkin3.4004.830Details
BioGPS Gene Atlas206703_atSmoothMuscle5.2504.830Details
BioGPS Gene Atlas206703_atSpinalcord4.9504.830Details
BioGPS Gene Atlas206703_atSubthalamicNucleus4.2004.830Details
BioGPS Gene Atlas206703_atSuperiorCervicalGanglion5.4004.830Details
BioGPS Gene Atlas206703_atTemporalLobe4.2504.830Details
BioGPS Gene Atlas206703_atTestis4.1004.830Details
BioGPS Gene Atlas206703_atTestisGermCell3.9004.830Details
BioGPS Gene Atlas206703_atTestisIntersitial4.0004.830Details
BioGPS Gene Atlas206703_atTestisLeydigCell4.6004.830Details
BioGPS Gene Atlas206703_atTestisSeminiferousTubule3.9004.830Details
BioGPS Gene Atlas206703_atThalamus4.7004.830Details
BioGPS Gene Atlas206703_atThymus3.7504.830Details
BioGPS Gene Atlas206703_atThyroid5.9504.830Details
BioGPS Gene Atlas206703_atTongue4.6004.830Details
BioGPS Gene Atlas206703_atTonsil4.5004.830Details
BioGPS Gene Atlas206703_atTrachea3.8504.830Details
BioGPS Gene Atlas206703_atTrigeminalGanglion4.6504.830Details
BioGPS Gene Atlas206703_atUterus3.7504.830Details
BioGPS Gene Atlas206703_atUterusCorpus4.0504.830Details
BioGPS Gene Atlas206703_atWholeBlood5.0004.830Details
BioGPS Gene Atlas206703_atWholebrain4.2504.830Details
BioGPS Gene Atlas206703_atcolon4.5504.830Details
BioGPS Gene Atlas206703_atpineal_day5.6404.830Details
BioGPS Gene Atlas206703_atpineal_night5.5604.830Details
BioGPS Gene Atlas206703_atretina5.5504.830Details
BioGPS Gene Atlas206703_atsmall_intestine4.4004.830Details
BioGPS NCI60206703_at7867.15410.270Details
BioGPS NCI60206703_atA1729.27610.270Details
BioGPS NCI60206703_atA2046.88010.270Details
BioGPS NCI60206703_atA3617.03610.270Details
BioGPS NCI60206703_atA4987.00210.270Details
BioGPS NCI60206703_atA5497.07010.270Details
BioGPS NCI60206703_atACC37.21210.270Details
BioGPS NCI60206703_atACHN128.61810.270Details
BioGPS NCI60206703_atALVA317.19310.270Details
BioGPS NCI60206703_atCAKI17.14910.270Details
BioGPS NCI60206703_atCCRT CEM9.23710.270Details
BioGPS NCI60206703_atCOLO2056.96710.270Details
BioGPS NCI60206703_atDLD17.20810.270Details
BioGPS NCI60206703_atDU14521.35910.270Details
BioGPS NCI60206703_atEKVX7.69410.270Details
BioGPS NCI60206703_atGM1338.77610.270Details
BioGPS NCI60206703_atGM16008.12610.270Details
BioGPS NCI60206703_atGM23137.09110.270Details
BioGPS NCI60206703_atGM23457.04810.270Details
BioGPS NCI60206703_atGM24937.44710.270Details
BioGPS NCI60206703_atGM977.42410.270Details
BioGPS NCI60206703_atHCC29986.72510.270Details
BioGPS NCI60206703_atHCT1166.98210.270Details
BioGPS NCI60206703_atHCT156.92910.270Details
BioGPS NCI60206703_atHEK 293 T-rex7.09910.270Details
BioGPS NCI60206703_atHEK 293T6.90010.270Details
BioGPS NCI60206703_atHEK2936.89010.270Details
BioGPS NCI60206703_atHELA6.76510.270Details
BioGPS NCI60206703_atHEPG27.25010.270Details
BioGPS NCI60206703_atHL607.14910.270Details
BioGPS NCI60206703_atHOP627.00310.270Details
BioGPS NCI60206703_atHOP927.38810.270Details
BioGPS NCI60206703_atHS578T7.00310.270Details
BioGPS NCI60206703_atHSG6.48910.270Details
BioGPS NCI60206703_atHT10807.02110.270Details
BioGPS NCI60206703_atHT297.26210.270Details
BioGPS NCI60206703_atIGROV16.97810.270Details
BioGPS NCI60206703_atIOSE806.83210.270Details
BioGPS NCI60206703_atJURKAT7.02010.270Details
BioGPS NCI60206703_atK5627.23410.270Details
BioGPS NCI60206703_atKM127.14610.270Details
BioGPS NCI60206703_atLN188.52110.270Details
BioGPS NCI60206703_atLNCAP6.97210.270Details
BioGPS NCI60206703_atLOX IMVI6.96410.270Details
BioGPS NCI60206703_atM146.54410.270Details
BioGPS NCI60206703_atMALME 3M7.23310.270Details
BioGPS NCI60206703_atMCF76.68610.270Details
BioGPS NCI60206703_atMD MB2319.42510.270Details
BioGPS NCI60206703_atMDA MB4357.21110.270Details
BioGPS NCI60206703_atMOLT47.93410.270Details
BioGPS NCI60206703_atNCI 4607.10210.270Details
BioGPS NCI60206703_atNCI H2267.13810.270Details
BioGPS NCI60206703_atNCI H236.99210.270Details
BioGPS NCI60206703_atNCI H322M6.87910.270Details
BioGPS NCI60206703_atNCVADR RES90.25810.270Details
BioGPS NCI60206703_atOVCAR37.19710.270Details
BioGPS NCI60206703_atOVCAR46.95510.270Details
BioGPS NCI60206703_atOVCAR56.46710.270Details
BioGPS NCI60206703_atOVCAR811.20110.270Details
BioGPS NCI60206703_atPANC130.42310.270Details
BioGPS NCI60206703_atRL77.10010.270Details
BioGPS NCI60206703_atRPMI 82268.25310.270Details
BioGPS NCI60206703_atRS118468.09310.270Details
BioGPS NCI60206703_atRXF3937.01710.270Details
BioGPS NCI60206703_atSAOS27.05810.270Details
BioGPS NCI60206703_atSF26821.43710.270Details
BioGPS NCI60206703_atSF2956.61610.270Details
BioGPS NCI60206703_atSF5396.15610.270Details
BioGPS NCI60206703_atSHSYSY+RA7.27810.270Details
BioGPS NCI60206703_atSHSYSY-RA7.00010.270Details
BioGPS NCI60206703_atSKMEL26.97910.270Details
BioGPS NCI60206703_atSKMEL287.03410.270Details
BioGPS NCI60206703_atSKMEL56.53810.270Details
BioGPS NCI60206703_atSKOV37.11310.270Details
BioGPS NCI60206703_atSN12C25.65810.270Details
BioGPS NCI60206703_atSNB196.52310.270Details
BioGPS NCI60206703_atSNB756.83210.270Details
BioGPS NCI60206703_atSR7.07310.270Details
BioGPS NCI60206703_atSW6207.43910.270Details
BioGPS NCI60206703_atT247.11110.270Details
BioGPS NCI60206703_atT3M47.15910.270Details
BioGPS NCI60206703_atTK106.99210.270Details
BioGPS NCI60206703_atU1187.00810.270Details
BioGPS NCI60206703_atU1388.32810.270Details
BioGPS NCI60206703_atU20S6.97710.270Details
BioGPS NCI60206703_atU2516.80910.270Details
BioGPS NCI60206703_atU876.77310.270Details
BioGPS NCI60206703_atUACC2576.75310.270Details
BioGPS NCI60206703_atUACC627.09810.270Details
BioGPS NCI60206703_atUO3157.08410.270Details
BioGPS NCI60206703_atZR75_17.79110.270Details
BioGPS NCI60206703_atastrocytes7.25110.270Details
BioGPS NCI60206703_athuh-77.16310.270Details