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Gene ID: 1135 | CHRNA2 Antibody Resource


CHRNA2 Antibody Resource
Gene Full Name: 
cholinergic receptor, nicotinic, alpha 2 (neuronal)
Uniprot: 
Q15822
Protein Name: 
neuronal acetylcholine receptor subunit alpha-2
Nucleotide: 
NM_000742
Alias: 
Ensembl: 
ENSG00000120903
Location: 
8p21
HPRD: 
00332
NCBI Gene: 
1135
MIM: 
118502

Summary: 
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence. [provided by RefSeq, Nov 2009]
Function: 
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular location: 
Cell junction › synapse › postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
PTM: 
Disulfide bond;
Disease: 
Epilepsy, nocturnal frontal lobe, 4 (ENFL4) [MIM:610353]: An autosomal dominant focal epilepsy characterized by nocturnal seizures associated with fear sensation, tongue movements, and nocturnal wandering, closely resembling nightmares and sleep walking. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody AVARP13064_T100 CHRNA2 antibody - N-terminal region (AVARP13064_T100) Polyclonal Human WB 100ug $229 Details
Polyclonal Antibody ARP34963_P050 CHRNA2 Antibody (ARP34963_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details
Polyclonal Antibody OAAB08182 CHRNA2 antibody - N - terminal region (OAAB08182) Human WB 400ul $289 Details

Show all CHRNA2 antibodies


Product Images
CHRNA2 antibody - N-terminal region (AVARP13064_T100) in HepG2, Raji cells using Western Blot

Sample Type: HepG2, Raji

CHRNA2 antibody - N - terminal region (OAAB08182) in Jurkat cells using Western Blot

Sample Type: Jurkat


CHRNA2 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP34963 African elephant CHRNA2 antibody; Loxodonta africana CHRNA2 antibody G3U3T3 86.0%
ARP34965 African elephant CHRNA2 antibody; Loxodonta africana CHRNA2 antibody G3U3T3 86.0%
ARP40684 Bovine CHRNA2 antibody; Bos taurus CHRNA2 antibody F1N4T3 100.0%
ARP34965 Bovine CHRNA2 antibody; Bos taurus CHRNA2 antibody F1N4T3 86.0%
ARP34963 Bovine CHRNA2 antibody; Bos taurus CHRNA2 antibody F1N4T3 85.0%
ARP34965 Cat CHRNA2 antibody; Felis catus CHRNA2 antibody M3WTL9 86.0%
ARP34963 Cat CHRNA2 antibody; Felis catus CHRNA2 antibody M3WTL9 79.0%
ARP34963 Chicken CHRNA2 antibody; Gallus gallus CHRNA2 antibody P09480 100.0%
ARP34963 Chicken CHRNA2 antibody; Gallus gallus CHRNA2 antibody F1NHP4 100.0%
ARP34965 Chicken CHRNA2 antibody; Gallus gallus CHRNA2 antibody P09480 79.0%
ARP34965 Chicken CHRNA2 antibody; Gallus gallus CHRNA2 antibody F1NHP4 79.0%
ARP30669 Chimpanzee CHRNA2 antibody; Pan troglodytes CHRNA2 antibody Q5IS52 100.0%
ARP34963 Chimpanzee CHRNA2 antibody; Pan troglodytes CHRNA2 antibody Q5IS52 100.0%
ARP34965 Chimpanzee CHRNA2 antibody; Pan troglodytes CHRNA2 antibody Q5IS52 86.0%
ARP34965 Chinese softshell turtle CHRNA2 antibody; Pelodiscus sinensis CHRNA2 antibody K7G1D9 86.0%
ARP34965 Collared flycatcher CHRNA2 antibody; Ficedula albicollis CHRNA2 antibody U3JM92 86.0%
ARP33158 Collared flycatcher CHRNA2 antibody; Ficedula albicollis CHRNA2 antibody U3JM92 82.0%
ARP34963 Dog CHRNA2 antibody; Canis familiaris CHRNA2 antibody E2R3I1 86.0%
ARP34965 Dog CHRNA2 antibody; Canis familiaris CHRNA2 antibody E2R3I1 86.0%
ARP34963 European domestic ferret CHRNA2 antibody; Mustela putorius furo CHRNA2 antibody M3XP72 100.0%
ARP34965 European domestic ferret CHRNA2 antibody; Mustela putorius furo CHRNA2 antibody M3XP72 79.0%
ARP40684 Giant panda CHRNA2 antibody; Ailuropoda melanoleuca CHRNA2 antibody G1KZY5 100.0%
ARP34965 Giant panda CHRNA2 antibody; Ailuropoda melanoleuca CHRNA2 antibody G1KZY5 86.0%
ARP34963 Giant panda CHRNA2 antibody; Ailuropoda melanoleuca CHRNA2 antibody G1KZY5 79.0%
ARP34965 Gray short-tailed opossum CHRNA2 antibody; Monodelphis domestica CHRNA2 antibody F6Z357 79.0%
ARP34965 Horse CHRNA2 antibody; Equus caballus CHRNA2 antibody F7BRT8 86.0%
ARP34963 Horse CHRNA2 antibody; Equus caballus CHRNA2 antibody F7BRT8 83.0%
ARP30669 Human CHRNA2 antibody; Homo sapiens CHRNA2 antibody Q15822 100.0%
ARP34963 Human CHRNA2 antibody; Homo sapiens CHRNA2 antibody Q15822 100.0%
ARP30669 Human CHRNA2 antibody; Homo sapiens CHRNA2 antibody E5RGP6 100.0%
ARP30669 Human CHRNA2 antibody; Homo sapiens CHRNA2 antibody E5RHQ4 100.0%
ARP34963 Human CHRNA2 antibody; Homo sapiens CHRNA2 antibody E5RHQ4 100.0%
ARP30669 Human CHRNA2 antibody; Homo sapiens CHRNA2 antibody E5RJ54 100.0%
ARP34963 Human CHRNA2 antibody; Homo sapiens CHRNA2 antibody E5RJ54 100.0%
ARP30669 Human CHRNA2 antibody; Homo sapiens CHRNA2 antibody E5RK67 100.0%
ARP34963 Human CHRNA2 antibody; Homo sapiens CHRNA2 antibody E5RK67 100.0%
ARP30669 Human CHRNA2 antibody; Homo sapiens CHRNA2 antibody J3KMY9 100.0%
ARP34963 Human CHRNA2 antibody; Homo sapiens CHRNA2 antibody J3KMY9 100.0%
ARP34965 Human CHRNA2 antibody; Homo sapiens CHRNA2 antibody Q15822 86.0%
ARP34965 Human CHRNA2 antibody; Homo sapiens CHRNA2 antibody E5RJ54 86.0%
ARP34965 Human CHRNA2 antibody; Homo sapiens CHRNA2 antibody E5RK67 86.0%
ARP34963 Mouse CHRNA2 antibody; Mus musculus CHRNA2 antibody Q91X60 86.0%
ARP34965 Mouse CHRNA2 antibody; Mus musculus CHRNA2 antibody Q91X60 86.0%
ARP30669 Northern white-cheeked gibbon CHRNA2 antibody; Nomascus leucogenys CHRNA2 antibody G1S2P3 100.0%
ARP34963 Northern white-cheeked gibbon CHRNA2 antibody; Nomascus leucogenys CHRNA2 antibody G1S2P3 93.0%
ARP34965 Northern white-cheeked gibbon CHRNA2 antibody; Nomascus leucogenys CHRNA2 antibody G1S2P3 86.0%
ARP34965 Pig CHRNA2 antibody; Sus scrofa CHRNA2 antibody F1RJS5 86.0%
ARP34963 Pig CHRNA2 antibody; Sus scrofa CHRNA2 antibody F1RJS5 79.0%
ARP34963 Rabbit CHRNA2 antibody; Oryctolagus cuniculus CHRNA2 antibody G1STJ9 86.0%
ARP34965 Rabbit CHRNA2 antibody; Oryctolagus cuniculus CHRNA2 antibody G1STJ9 86.0%
ARP34963 Rat CHRNA2 antibody; Rattus norvegicus CHRNA2 antibody P12389 86.0%
ARP34965 Rat CHRNA2 antibody; Rattus norvegicus CHRNA2 antibody P12389 86.0%
ARP30669 Rhesus macaque CHRNA2 antibody; Macaca mulatta CHRNA2 antibody F7FFT5 100.0%
ARP34963 Rhesus macaque CHRNA2 antibody; Macaca mulatta CHRNA2 antibody F7FFT5 86.0%
ARP34965 Rhesus macaque CHRNA2 antibody; Macaca mulatta CHRNA2 antibody F7FFT5 86.0%
ARP34965 Small-eared galago CHRNA2 antibody; Otolemur garnettii CHRNA2 antibody H0XU48 86.0%
ARP34963 Small-eared galago CHRNA2 antibody; Otolemur garnettii CHRNA2 antibody H0XU48 79.0%
ARP30669 Sumatran orangutan CHRNA2 antibody; Pongo abelii CHRNA2 antibody H2PPW6 100.0%
ARP34963 Sumatran orangutan CHRNA2 antibody; Pongo abelii CHRNA2 antibody H2PPW6 93.0%
ARP34965 Sumatran orangutan CHRNA2 antibody; Pongo abelii CHRNA2 antibody H2PPW6 86.0%
ARP70134 Tasmanian devil CHRNA2 antibody; Sarcophilus harrisii CHRNA2 antibody G3VC89 90.0%
ARP70134 Tasmanian devil CHRNA2 antibody; Sarcophilus harrisii CHRNA2 antibody G3VC90 90.0%
ARP34965 Tasmanian devil CHRNA2 antibody; Sarcophilus harrisii CHRNA2 antibody G3VC89 79.0%
ARP34965 Tasmanian devil CHRNA2 antibody; Sarcophilus harrisii CHRNA2 antibody G3VC90 79.0%
ARP30671 Western clawed frog CHRNA2 antibody; Xenopus tropicalis CHRNA2 antibody F6YPK2 79.0%
ARP34965 Western clawed frog CHRNA2 antibody; Xenopus tropicalis CHRNA2 antibody F6YPK2 79.0%
ARP30669 White-tufted-ear marmoset CHRNA2 antibody; Callithrix jacchus CHRNA2 antibody F7F976 93.0%
ARP30669 White-tufted-ear marmoset CHRNA2 antibody; Callithrix jacchus CHRNA2 antibody F6Q5Q9 93.0%
ARP34963 White-tufted-ear marmoset CHRNA2 antibody; Callithrix jacchus CHRNA2 antibody F7F976 86.0%
ARP34963 White-tufted-ear marmoset CHRNA2 antibody; Callithrix jacchus CHRNA2 antibody F6Q5Q9 86.0%
ARP34965 White-tufted-ear marmoset CHRNA2 antibody; Callithrix jacchus CHRNA2 antibody F6Q5Q9 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas207868_at721_B_lymphoblasts8.3008.000Details
BioGPS Gene Atlas207868_atAdipocyte7.0508.000Details
BioGPS Gene Atlas207868_atAdrenalCortex7.5508.000Details
BioGPS Gene Atlas207868_atAdrenalgland5.9508.000Details
BioGPS Gene Atlas207868_atAmygdala8.0008.000Details
BioGPS Gene Atlas207868_atAppendix7.4008.000Details
BioGPS Gene Atlas207868_atAtrioventricularNode5.4508.000Details
BioGPS Gene Atlas207868_atBDCA4+_DentriticCells7.9508.000Details
BioGPS Gene Atlas207868_atBonemarrow10.8008.000Details
BioGPS Gene Atlas207868_atBronchialEpithelialCells7.0008.000Details
BioGPS Gene Atlas207868_atCD105+_Endothelial7.2508.000Details
BioGPS Gene Atlas207868_atCD14+_Monocytes7.7008.000Details
BioGPS Gene Atlas207868_atCD19+_BCells(neg._sel.)7.7508.000Details
BioGPS Gene Atlas207868_atCD33+_Myeloid11.6508.000Details
BioGPS Gene Atlas207868_atCD34+8.7008.000Details
BioGPS Gene Atlas207868_atCD4+_Tcells8.0008.000Details
BioGPS Gene Atlas207868_atCD56+_NKCells7.6508.000Details
BioGPS Gene Atlas207868_atCD71+_EarlyErythroid6.4008.000Details
BioGPS Gene Atlas207868_atCD8+_Tcells7.1008.000Details
BioGPS Gene Atlas207868_atCardiacMyocytes9.5008.000Details
BioGPS Gene Atlas207868_atCaudatenucleus6.4008.000Details
BioGPS Gene Atlas207868_atCerebellum5.8008.000Details
BioGPS Gene Atlas207868_atCerebellumPeduncles8.0508.000Details
BioGPS Gene Atlas207868_atCiliaryGanglion4.9508.000Details
BioGPS Gene Atlas207868_atCingulateCortex7.2508.000Details
BioGPS Gene Atlas207868_atColorectaladenocarcinoma8.7508.000Details
BioGPS Gene Atlas207868_atDorsalRootGanglion5.5008.000Details
BioGPS Gene Atlas207868_atFetalThyroid6.9508.000Details
BioGPS Gene Atlas207868_atFetalbrain7.2508.000Details
BioGPS Gene Atlas207868_atFetalliver6.2008.000Details
BioGPS Gene Atlas207868_atFetallung6.0508.000Details
BioGPS Gene Atlas207868_atGlobusPallidus5.1008.000Details
BioGPS Gene Atlas207868_atHeart27.3508.000Details
BioGPS Gene Atlas207868_atHypothalamus7.9508.000Details
BioGPS Gene Atlas207868_atKidney5.7008.000Details
BioGPS Gene Atlas207868_atLeukemia_chronicMyelogenousK-5626.5008.000Details
BioGPS Gene Atlas207868_atLeukemia_promyelocytic-HL-606.2508.000Details
BioGPS Gene Atlas207868_atLeukemialymphoblastic(MOLT-4)5.9508.000Details
BioGPS Gene Atlas207868_atLiver9.9008.000Details
BioGPS Gene Atlas207868_atLung7.9508.000Details
BioGPS Gene Atlas207868_atLymphnode6.1508.000Details
BioGPS Gene Atlas207868_atLymphoma_burkitts(Daudi)9.1508.000Details
BioGPS Gene Atlas207868_atLymphoma_burkitts(Raji)18.1008.000Details
BioGPS Gene Atlas207868_atMedullaOblongata8.3508.000Details
BioGPS Gene Atlas207868_atOccipitalLobe5.4508.000Details
BioGPS Gene Atlas207868_atOlfactoryBulb5.6008.000Details
BioGPS Gene Atlas207868_atOvary8.3508.000Details
BioGPS Gene Atlas207868_atPancreas5.7508.000Details
BioGPS Gene Atlas207868_atPancreaticIslet7.6508.000Details
BioGPS Gene Atlas207868_atParietalLobe7.4008.000Details
BioGPS Gene Atlas207868_atPituitary8.3508.000Details
BioGPS Gene Atlas207868_atPlacenta7.4008.000Details
BioGPS Gene Atlas207868_atPons6.7508.000Details
BioGPS Gene Atlas207868_atPrefrontalCortex8.3008.000Details
BioGPS Gene Atlas207868_atProstate8.6508.000Details
BioGPS Gene Atlas207868_atSalivarygland5.6508.000Details
BioGPS Gene Atlas207868_atSkeletalMuscle12.3008.000Details
BioGPS Gene Atlas207868_atSkin6.2508.000Details
BioGPS Gene Atlas207868_atSmoothMuscle9.2008.000Details
BioGPS Gene Atlas207868_atSpinalcord7.6508.000Details
BioGPS Gene Atlas207868_atSubthalamicNucleus6.4008.000Details
BioGPS Gene Atlas207868_atSuperiorCervicalGanglion11.6508.000Details
BioGPS Gene Atlas207868_atTemporalLobe6.2508.000Details
BioGPS Gene Atlas207868_atTestis6.2508.000Details
BioGPS Gene Atlas207868_atTestisGermCell6.1008.000Details
BioGPS Gene Atlas207868_atTestisIntersitial5.8008.000Details
BioGPS Gene Atlas207868_atTestisLeydigCell8.7008.000Details
BioGPS Gene Atlas207868_atTestisSeminiferousTubule7.8508.000Details
BioGPS Gene Atlas207868_atThalamus6.7008.000Details
BioGPS Gene Atlas207868_atThymus5.7508.000Details
BioGPS Gene Atlas207868_atThyroid11.6508.000Details
BioGPS Gene Atlas207868_atTongue6.9508.000Details
BioGPS Gene Atlas207868_atTonsil7.0008.000Details
BioGPS Gene Atlas207868_atTrachea7.5008.000Details
BioGPS Gene Atlas207868_atTrigeminalGanglion10.2508.000Details
BioGPS Gene Atlas207868_atUterus7.8008.000Details
BioGPS Gene Atlas207868_atUterusCorpus6.4508.000Details
BioGPS Gene Atlas207868_atWholeBlood8.0008.000Details
BioGPS Gene Atlas207868_atWholebrain5.9008.000Details
BioGPS Gene Atlas207868_atcolon12.9008.000Details
BioGPS Gene Atlas207868_atpineal_day8.7608.000Details
BioGPS Gene Atlas207868_atpineal_night8.4808.000Details
BioGPS Gene Atlas207868_atretina10.3508.000Details
BioGPS Gene Atlas207868_atsmall_intestine8.9508.000Details
BioGPS NCI60207868_at78634.54036.060Details
BioGPS NCI60207868_atA17233.30536.060Details
BioGPS NCI60207868_atA20433.49336.060Details
BioGPS NCI60207868_atA36134.16536.060Details
BioGPS NCI60207868_atA49834.01836.060Details
BioGPS NCI60207868_atA54934.24436.060Details
BioGPS NCI60207868_atACC334.78936.060Details
BioGPS NCI60207868_atACHN27.39836.060Details
BioGPS NCI60207868_atALVA3134.69336.060Details
BioGPS NCI60207868_atCAKI145.98236.060Details
BioGPS NCI60207868_atCCRT CEM37.71136.060Details
BioGPS NCI60207868_atCOLO20542.20536.060Details
BioGPS NCI60207868_atDLD133.43436.060Details
BioGPS NCI60207868_atDU14560.17736.060Details
BioGPS NCI60207868_atEKVX32.91636.060Details
BioGPS NCI60207868_atGM13337.21936.060Details
BioGPS NCI60207868_atGM160034.30136.060Details
BioGPS NCI60207868_atGM231333.94736.060Details
BioGPS NCI60207868_atGM234534.00636.060Details
BioGPS NCI60207868_atGM249332.59836.060Details
BioGPS NCI60207868_atGM9734.89336.060Details
BioGPS NCI60207868_atHCC299821.61436.060Details
BioGPS NCI60207868_atHCT11633.51736.060Details
BioGPS NCI60207868_atHCT1528.73536.060Details
BioGPS NCI60207868_atHEK 293 T-rex79.07636.060Details
BioGPS NCI60207868_atHEK 293T34.06936.060Details
BioGPS NCI60207868_atHEK29334.04436.060Details
BioGPS NCI60207868_atHELA32.83836.060Details
BioGPS NCI60207868_atHEPG233.39236.060Details
BioGPS NCI60207868_atHL6033.92036.060Details
BioGPS NCI60207868_atHOP6234.01836.060Details
BioGPS NCI60207868_atHOP9233.43236.060Details
BioGPS NCI60207868_atHS578T33.50636.060Details
BioGPS NCI60207868_atHSG33.21236.060Details
BioGPS NCI60207868_atHT108033.59336.060Details
BioGPS NCI60207868_atHT2952.48236.060Details
BioGPS NCI60207868_atIGROV133.26336.060Details
BioGPS NCI60207868_atIOSE8029.00336.060Details
BioGPS NCI60207868_atJURKAT47.44936.060Details
BioGPS NCI60207868_atK56234.91636.060Details
BioGPS NCI60207868_atKM1234.57136.060Details
BioGPS NCI60207868_atLN1833.11336.060Details
BioGPS NCI60207868_atLNCAP33.82636.060Details
BioGPS NCI60207868_atLOX IMVI33.83136.060Details
BioGPS NCI60207868_atM1430.25036.060Details
BioGPS NCI60207868_atMALME 3M34.94236.060Details
BioGPS NCI60207868_atMCF728.41936.060Details
BioGPS NCI60207868_atMD MB23170.26036.060Details
BioGPS NCI60207868_atMDA MB43534.81636.060Details
BioGPS NCI60207868_atMOLT434.34636.060Details
BioGPS NCI60207868_atNCI 46046.74236.060Details
BioGPS NCI60207868_atNCI H22633.78536.060Details
BioGPS NCI60207868_atNCI H2342.56236.060Details
BioGPS NCI60207868_atNCI H322M33.90136.060Details
BioGPS NCI60207868_atNCVADR RES27.63636.060Details
BioGPS NCI60207868_atOVCAR334.42936.060Details
BioGPS NCI60207868_atOVCAR436.07636.060Details
BioGPS NCI60207868_atOVCAR533.61736.060Details
BioGPS NCI60207868_atOVCAR816.44936.060Details
BioGPS NCI60207868_atPANC133.99336.060Details
BioGPS NCI60207868_atRL734.01736.060Details
BioGPS NCI60207868_atRPMI 822637.25936.060Details
BioGPS NCI60207868_atRS1184634.64536.060Details
BioGPS NCI60207868_atRXF39333.57136.060Details
BioGPS NCI60207868_atSAOS241.57936.060Details
BioGPS NCI60207868_atSF26842.46236.060Details
BioGPS NCI60207868_atSF29533.51936.060Details
BioGPS NCI60207868_atSF53933.04136.060Details
BioGPS NCI60207868_atSHSYSY+RA33.29636.060Details
BioGPS NCI60207868_atSHSYSY-RA33.70036.060Details
BioGPS NCI60207868_atSKMEL233.78036.060Details
BioGPS NCI60207868_atSKMEL2833.71836.060Details
BioGPS NCI60207868_atSKMEL533.16536.060Details
BioGPS NCI60207868_atSKOV334.19636.060Details
BioGPS NCI60207868_atSN12C31.97736.060Details
BioGPS NCI60207868_atSNB1927.79736.060Details
BioGPS NCI60207868_atSNB7533.84136.060Details
BioGPS NCI60207868_atSR34.36436.060Details
BioGPS NCI60207868_atSW62033.64136.060Details
BioGPS NCI60207868_atT2447.98836.060Details
BioGPS NCI60207868_atT3M443.35136.060Details
BioGPS NCI60207868_atTK1033.71936.060Details
BioGPS NCI60207868_atU11832.77036.060Details
BioGPS NCI60207868_atU13833.16436.060Details
BioGPS NCI60207868_atU20S34.11836.060Details
BioGPS NCI60207868_atU25133.72536.060Details
BioGPS NCI60207868_atU8733.57336.060Details
BioGPS NCI60207868_atUACC25734.82836.060Details
BioGPS NCI60207868_atUACC6234.63836.060Details
BioGPS NCI60207868_atUO3118.28336.060Details
BioGPS NCI60207868_atZR75_130.14536.060Details
BioGPS NCI60207868_atastrocytes34.53336.060Details
BioGPS NCI60207868_athuh-753.45036.060Details