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Gene ID: 91851 | CHRDL1 Antibody Resource


CHRDL1 Antibody Resource
Gene Full Name: 
chordin-like 1
Uniprot: 
Q9BU40
Protein Name: 
chordin-like protein 1
Nucleotide: 
NM_001143983
Alias: 
CHL;VOPT;NRLN1;dA141H5.1;
Ensembl: 
ENSG00000101938
Location: 
Xq23
HPRD: 
02285
NCBI Gene: 
91851
MIM: 
300350

Summary: 
This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]
Function: 
Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation . May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.
Subcellular location: 
Secreted Potential.
PTM: 
Glycoprotein;
Disease: 
Megalocornea 1, X-linked (MGC1) [MIM:309300]: An eye disorder in which the corneal diameter is bilaterally enlarged (greater than 13 mm) without an increase in intraocular pressure. It may also be referred to as anterior megalophthalmos, since the entire anterior segment is larger than normal. Features of megalocornea in addition to a deep anterior chamber include astigmatic refractive errors, atrophy of the iris stroma, miosis secondary to decreased function of the dilator muscle, iridodonesis, and tremulousness, subluxation, or dislocation of the lens. Whereas most affected individuals exhibit normal ocular function, complications include cataract development and glaucoma following lenticular dislocation or subluxation. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB00684 CHRDL1 antibody - N-terminal region (OAAB00684) Human WB, IHC, ELISA 400ul $289 Details

Show all CHRDL1 antibodies


Product Images
CHRDL1 antibody - N-terminal region (OAAB00684) in 293 cells using Western Blot

Sample Type: 293

CHRDL1 antibody - N-terminal region (OAAB00684) in human hepatocarcinoma cells using Immunohistochemistry

Sample Type: human hepatocarcinoma


CHRDL1 Protocols

Publications

Related Gene Trend Categories

Species
Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas209763_at721_B_lymphoblasts7.05042.770Details
BioGPS Gene Atlas209763_atAdipocyte568.90042.770Details
BioGPS Gene Atlas209763_atAdrenalCortex7.45042.770Details
BioGPS Gene Atlas209763_atAdrenalgland5.90042.770Details
BioGPS Gene Atlas209763_atAmygdala40.90042.770Details
BioGPS Gene Atlas209763_atAppendix52.65042.770Details
BioGPS Gene Atlas209763_atAtrioventricularNode17.45042.770Details
BioGPS Gene Atlas209763_atBDCA4+_DentriticCells5.90042.770Details
BioGPS Gene Atlas209763_atBonemarrow6.85042.770Details
BioGPS Gene Atlas209763_atBronchialEpithelialCells5.40042.770Details
BioGPS Gene Atlas209763_atCD105+_Endothelial105.15042.770Details
BioGPS Gene Atlas209763_atCD14+_Monocytes6.50042.770Details
BioGPS Gene Atlas209763_atCD19+_BCells(neg._sel.)7.00042.770Details
BioGPS Gene Atlas209763_atCD33+_Myeloid8.85042.770Details
BioGPS Gene Atlas209763_atCD34+8.95042.770Details
BioGPS Gene Atlas209763_atCD4+_Tcells6.35042.770Details
BioGPS Gene Atlas209763_atCD56+_NKCells7.15042.770Details
BioGPS Gene Atlas209763_atCD71+_EarlyErythroid5.95042.770Details
BioGPS Gene Atlas209763_atCD8+_Tcells5.50042.770Details
BioGPS Gene Atlas209763_atCardiacMyocytes9.65042.770Details
BioGPS Gene Atlas209763_atCaudatenucleus22.45042.770Details
BioGPS Gene Atlas209763_atCerebellum7.05042.770Details
BioGPS Gene Atlas209763_atCerebellumPeduncles8.45042.770Details
BioGPS Gene Atlas209763_atCiliaryGanglion30.95042.770Details
BioGPS Gene Atlas209763_atCingulateCortex7.75042.770Details
BioGPS Gene Atlas209763_atColorectaladenocarcinoma6.75042.770Details
BioGPS Gene Atlas209763_atDorsalRootGanglion78.10042.770Details
BioGPS Gene Atlas209763_atFetalThyroid13.40042.770Details
BioGPS Gene Atlas209763_atFetalbrain26.95042.770Details
BioGPS Gene Atlas209763_atFetalliver4.90042.770Details
BioGPS Gene Atlas209763_atFetallung6.40042.770Details
BioGPS Gene Atlas209763_atGlobusPallidus5.55042.770Details
BioGPS Gene Atlas209763_atHeart9.65042.770Details
BioGPS Gene Atlas209763_atHypothalamus7.80042.770Details
BioGPS Gene Atlas209763_atKidney5.95042.770Details
BioGPS Gene Atlas209763_atLeukemia_chronicMyelogenousK-5625.60042.770Details
BioGPS Gene Atlas209763_atLeukemia_promyelocytic-HL-605.05042.770Details
BioGPS Gene Atlas209763_atLeukemialymphoblastic(MOLT-4)4.90042.770Details
BioGPS Gene Atlas209763_atLiver8.05042.770Details
BioGPS Gene Atlas209763_atLung20.75042.770Details
BioGPS Gene Atlas209763_atLymphnode91.45042.770Details
BioGPS Gene Atlas209763_atLymphoma_burkitts(Daudi)7.20042.770Details
BioGPS Gene Atlas209763_atLymphoma_burkitts(Raji)9.25042.770Details
BioGPS Gene Atlas209763_atMedullaOblongata8.95042.770Details
BioGPS Gene Atlas209763_atOccipitalLobe51.70042.770Details
BioGPS Gene Atlas209763_atOlfactoryBulb223.35042.770Details
BioGPS Gene Atlas209763_atOvary5.50042.770Details
BioGPS Gene Atlas209763_atPancreas5.10042.770Details
BioGPS Gene Atlas209763_atPancreaticIslet7.20042.770Details
BioGPS Gene Atlas209763_atParietalLobe10.05042.770Details
BioGPS Gene Atlas209763_atPituitary7.65042.770Details
BioGPS Gene Atlas209763_atPlacenta46.25042.770Details
BioGPS Gene Atlas209763_atPons6.95042.770Details
BioGPS Gene Atlas209763_atPrefrontalCortex29.00042.770Details
BioGPS Gene Atlas209763_atProstate139.15042.770Details
BioGPS Gene Atlas209763_atSalivarygland15.15042.770Details
BioGPS Gene Atlas209763_atSkeletalMuscle8.10042.770Details
BioGPS Gene Atlas209763_atSkin20.15042.770Details
BioGPS Gene Atlas209763_atSmoothMuscle6.25042.770Details
BioGPS Gene Atlas209763_atSpinalcord8.05042.770Details
BioGPS Gene Atlas209763_atSubthalamicNucleus6.40042.770Details
BioGPS Gene Atlas209763_atSuperiorCervicalGanglion39.35042.770Details
BioGPS Gene Atlas209763_atTemporalLobe9.15042.770Details
BioGPS Gene Atlas209763_atTestis5.25042.770Details
BioGPS Gene Atlas209763_atTestisGermCell45.95042.770Details
BioGPS Gene Atlas209763_atTestisIntersitial6.35042.770Details
BioGPS Gene Atlas209763_atTestisLeydigCell9.70042.770Details
BioGPS Gene Atlas209763_atTestisSeminiferousTubule5.50042.770Details
BioGPS Gene Atlas209763_atThalamus6.50042.770Details
BioGPS Gene Atlas209763_atThymus12.65042.770Details
BioGPS Gene Atlas209763_atThyroid177.00042.770Details
BioGPS Gene Atlas209763_atTongue99.85042.770Details
BioGPS Gene Atlas209763_atTonsil6.05042.770Details
BioGPS Gene Atlas209763_atTrachea32.75042.770Details
BioGPS Gene Atlas209763_atTrigeminalGanglion42.20042.770Details
BioGPS Gene Atlas209763_atUterus495.15042.770Details
BioGPS Gene Atlas209763_atUterusCorpus171.05042.770Details
BioGPS Gene Atlas209763_atWholeBlood7.35042.770Details
BioGPS Gene Atlas209763_atWholebrain59.90042.770Details
BioGPS Gene Atlas209763_atcolon114.55042.770Details
BioGPS Gene Atlas209763_atpineal_day7.78042.770Details
BioGPS Gene Atlas209763_atpineal_night7.72042.770Details
BioGPS Gene Atlas209763_atretina234.82542.770Details
BioGPS Gene Atlas209763_atsmall_intestine20.60042.770Details
BioGPS NCI60209763_at7862560.800151.380Details
BioGPS NCI60209763_atA1724.955151.380Details
BioGPS NCI60209763_atA2045.363151.380Details
BioGPS NCI60209763_atA3615.533151.380Details
BioGPS NCI60209763_atA4985.469151.380Details
BioGPS NCI60209763_atA5495.596151.380Details
BioGPS NCI60209763_atACC36.067151.380Details
BioGPS NCI60209763_atACHN161.472151.380Details
BioGPS NCI60209763_atALVA316.165151.380Details
BioGPS NCI60209763_atCAKI15.854151.380Details
BioGPS NCI60209763_atCCRT CEM7.078151.380Details
BioGPS NCI60209763_atCOLO2055.559151.380Details
BioGPS NCI60209763_atDLD15.243151.380Details
BioGPS NCI60209763_atDU1455.100151.380Details
BioGPS NCI60209763_atEKVX4.905151.380Details
BioGPS NCI60209763_atGM1337.315151.380Details
BioGPS NCI60209763_atGM160049.926151.380Details
BioGPS NCI60209763_atGM231320.559151.380Details
BioGPS NCI60209763_atGM234533.761151.380Details
BioGPS NCI60209763_atGM249337.762151.380Details
BioGPS NCI60209763_atGM971382.669151.380Details
BioGPS NCI60209763_atHCC29984.668151.380Details
BioGPS NCI60209763_atHCT1165.434151.380Details
BioGPS NCI60209763_atHCT154.748151.380Details
BioGPS NCI60209763_atHEK 293 T-rex6.024151.380Details
BioGPS NCI60209763_atHEK 293T5.422151.380Details
BioGPS NCI60209763_atHEK2935.553151.380Details
BioGPS NCI60209763_atHELA4.720151.380Details
BioGPS NCI60209763_atHEPG25.451151.380Details
BioGPS NCI60209763_atHL605.828151.380Details
BioGPS NCI60209763_atHOP6220.206151.380Details
BioGPS NCI60209763_atHOP925.162151.380Details
BioGPS NCI60209763_atHS578T5.359151.380Details
BioGPS NCI60209763_atHSG4.948151.380Details
BioGPS NCI60209763_atHT10805.283151.380Details
BioGPS NCI60209763_atHT296.402151.380Details
BioGPS NCI60209763_atIGROV15.287151.380Details
BioGPS NCI60209763_atIOSE805.351151.380Details
BioGPS NCI60209763_atJURKAT5.458151.380Details
BioGPS NCI60209763_atK5626.263151.380Details
BioGPS NCI60209763_atKM126.053151.380Details
BioGPS NCI60209763_atLN184.926151.380Details
BioGPS NCI60209763_atLNCAP5.480151.380Details
BioGPS NCI60209763_atLOX IMVI5.473151.380Details
BioGPS NCI60209763_atM145.381151.380Details
BioGPS NCI60209763_atMALME 3M6.000151.380Details
BioGPS NCI60209763_atMCF75.183151.380Details
BioGPS NCI60209763_atMD MB2315.598151.380Details
BioGPS NCI60209763_atMDA MB4356.889151.380Details
BioGPS NCI60209763_atMOLT45.896151.380Details
BioGPS NCI60209763_atNCI 4605.615151.380Details
BioGPS NCI60209763_atNCI H2265.900151.380Details
BioGPS NCI60209763_atNCI H235.569151.380Details
BioGPS NCI60209763_atNCI H322M5.563151.380Details
BioGPS NCI60209763_atNCVADR RES438.714151.380Details
BioGPS NCI60209763_atOVCAR35.978151.380Details
BioGPS NCI60209763_atOVCAR45.438151.380Details
BioGPS NCI60209763_atOVCAR55.377151.380Details
BioGPS NCI60209763_atOVCAR8657.099151.380Details
BioGPS NCI60209763_atPANC15.538151.380Details
BioGPS NCI60209763_atRL75.625151.380Details
BioGPS NCI60209763_atRPMI 82265.626151.380Details
BioGPS NCI60209763_atRS118465.934151.380Details
BioGPS NCI60209763_atRXF393850.882151.380Details
BioGPS NCI60209763_atSAOS25.509151.380Details
BioGPS NCI60209763_atSF26833.865151.380Details
BioGPS NCI60209763_atSF2955.157151.380Details
BioGPS NCI60209763_atSF5395.247151.380Details
BioGPS NCI60209763_atSHSYSY+RA5.470151.380Details
BioGPS NCI60209763_atSHSYSY-RA5.405151.380Details
BioGPS NCI60209763_atSKMEL25.469151.380Details
BioGPS NCI60209763_atSKMEL285.484151.380Details
BioGPS NCI60209763_atSKMEL55.076151.380Details
BioGPS NCI60209763_atSKOV35.773151.380Details
BioGPS NCI60209763_atSN12C5877.832151.380Details
BioGPS NCI60209763_atSNB194.964151.380Details
BioGPS NCI60209763_atSNB752103.615151.380Details
BioGPS NCI60209763_atSR5.725151.380Details
BioGPS NCI60209763_atSW6205.662151.380Details
BioGPS NCI60209763_atT245.677151.380Details
BioGPS NCI60209763_atT3M45.865151.380Details
BioGPS NCI60209763_atTK105.524151.380Details
BioGPS NCI60209763_atU1185.535151.380Details
BioGPS NCI60209763_atU138555.369151.380Details
BioGPS NCI60209763_atU20S5.489151.380Details
BioGPS NCI60209763_atU251166.283151.380Details
BioGPS NCI60209763_atU875.369151.380Details
BioGPS NCI60209763_atUACC2575.461151.380Details
BioGPS NCI60209763_atUACC62338.508151.380Details
BioGPS NCI60209763_atUO314.996151.380Details
BioGPS NCI60209763_atZR75_15.764151.380Details
BioGPS NCI60209763_atastrocytes7.957151.380Details
BioGPS NCI60209763_athuh-75.774151.380Details