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Gene ID: 79643 | CHMP6 Antibody Resource


CHMP6 Antibody Resource
Gene Full Name: 
charged multivesicular body protein 6
Uniprot: 
Q96FZ7
Protein Name: 
charged multivesicular body protein 6
Nucleotide: 
NM_024591
Alias: 
VPS20;
Ensembl: 
ENSG00000176108
Location: 
17q25.3
HPRD: 
08564
NCBI Gene: 
79643
MIM: 
610901

Summary: 
This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein family. Proteins in this family are part of the ESCRT-III (endosomal sorting complex required for transport III) which degrades surface receptors, and in biosynthesis of endosomes. [provided by RefSeq, Mar 2012]
Function: 
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. In the ESCRT-III complex, it probably serves as an acceptor for the ESCRT-II complex on endosomal membranes.
Subcellular location: 
Endomembrane system. Endosome membrane; Lipid-anchor. Late endosome membrane Probable. Note: Localizes to endosomal membranes.
PTM: 
Lipoprotein;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP65538_P050 CHMP6 Antibody - middle region (ARP65538_P050) Human WB 50ug $289 Details
Polyclonal Antibody ARP65537_P050 CHMP6 Antibody (ARP65537_P050) Polyclonal Bovine, Guinea pig, Human, Mouse, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB08723 CHMP6 antibody - N - terminal region (OAAB08723) Human WB 400ul $289 Details

Show all CHMP6 antibodies


Product Images
CHMP6 Antibody - middle region (ARP65538_P050) in Human HepG2 cells using Western Blot

Sample Type: Human HepG2

CHMP6 antibody - N - terminal region (OAAB08723) in 293 cells using Western Blot

Sample Type: 293


CHMP6 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP65537 Bovine CHMP6 antibody; Bos taurus CHMP6 antibody Q148L0 100.0%
ARP65538 Bovine CHMP6 antibody; Bos taurus CHMP6 antibody Q148L0 93.0%
ARP65538 Cat CHMP6 antibody; Felis catus CHMP6 antibody M3XCL3 93.0%
ARP65538 Chicken CHMP6 antibody; Gallus gallus CHMP6 antibody Q5ZL55 92.0%
ARP65538 Chicken CHMP6 antibody; Gallus gallus CHMP6 antibody R4GH14 92.0%
ARP65537 Chicken CHMP6 antibody; Gallus gallus CHMP6 antibody Q5ZL55 86.0%
ARP65537 Chimpanzee CHMP6 antibody; Pan troglodytes CHMP6 antibody K7APD9 100.0%
ARP65537 Chimpanzee CHMP6 antibody; Pan troglodytes CHMP6 antibody K7B847 100.0%
ARP65538 Chimpanzee CHMP6 antibody; Pan troglodytes CHMP6 antibody K7APD9 93.0%
ARP65538 Chimpanzee CHMP6 antibody; Pan troglodytes CHMP6 antibody K7B847 93.0%
ARP65538 Chimpanzee CHMP6 antibody; Pan troglodytes CHMP6 antibody H2QE17 93.0%
ARP65538 Chinese softshell turtle CHMP6 antibody; Pelodiscus sinensis CHMP6 antibody K7GHS1 93.0%
ARP65538 Collared flycatcher CHMP6 antibody; Ficedula albicollis CHMP6 antibody U3KDM1 92.0%
ARP65538 Dog CHMP6 antibody; Canis familiaris CHMP6 antibody F1PRE3 93.0%
ARP65538 Domestic duck CHMP6 antibody; Anas platyrhynchos CHMP6 antibody U3IY50 92.0%
ARP65538 Duckbill platypus CHMP6 antibody; Ornithorhynchus anatinus CHMP6 antibody F7CEQ0 86.0%
ARP65538 European domestic ferret CHMP6 antibody; Mustela putorius furo CHMP6 antibody M3YKE2 93.0%
ARP65538 Giant panda CHMP6 antibody; Ailuropoda melanoleuca CHMP6 antibody G1MA41 93.0%
ARP65537 Gray short-tailed opossum CHMP6 antibody; Monodelphis domestica CHMP6 antibody F7DEF6 93.0%
ARP65538 Gray short-tailed opossum CHMP6 antibody; Monodelphis domestica CHMP6 antibody F7DEF6 79.0%
ARP65538 Horse CHMP6 antibody; Equus caballus CHMP6 antibody F6SFH9 100.0%
ARP65538 Human CHMP6 antibody; Homo sapiens CHMP6 antibody I3L3E4 100.0%
ARP65538 Human CHMP6 antibody; Homo sapiens CHMP6 antibody I3L4A1 100.0%
ARP65538 Human CHMP6 antibody; Homo sapiens CHMP6 antibody I3L4G8 100.0%
ARP65537 Human CHMP6 antibody; Homo sapiens CHMP6 antibody Q96FZ7 100.0%
ARP65538 Human CHMP6 antibody; Homo sapiens CHMP6 antibody Q96FZ7 100.0%
ARP65538 Mouse CHMP6 antibody; Mus musculus CHMP6 antibody B1AZ39 100.0%
ARP65538 Mouse CHMP6 antibody; Mus musculus CHMP6 antibody B1AZ42 100.0%
ARP65538 Mouse CHMP6 antibody; Mus musculus CHMP6 antibody P0C0A3 100.0%
ARP65538 Mouse CHMP6 antibody; Mus musculus CHMP6 antibody Q3TS10 100.0%
ARP65537 Mouse CHMP6 antibody; Mus musculus CHMP6 antibody B1AZ39 93.0%
ARP65537 Mouse CHMP6 antibody; Mus musculus CHMP6 antibody P0C0A3 93.0%
ARP65538 Pig CHMP6 antibody; Sus scrofa CHMP6 antibody F1RZY6 100.0%
ARP65538 Rainbow smelt CHMP6 antibody; Osmerus mordax CHMP6 antibody C1BLT9 86.0%
ARP65538 Rainbow smelt CHMP6 antibody; Osmerus mordax CHMP6 antibody C1BJC1 79.0%
ARP65538 Rat CHMP6 antibody; Rattus norvegicus CHMP6 antibody D3ZDR2 100.0%
ARP65537 Rat CHMP6 antibody; Rattus norvegicus CHMP6 antibody D3ZDR2 93.0%
ARP65537 Rhesus macaque CHMP6 antibody; Macaca mulatta CHMP6 antibody H9FZT3 100.0%
ARP65538 Rhesus macaque CHMP6 antibody; Macaca mulatta CHMP6 antibody H9FZT3 100.0%
ARP65538 Sablefish CHMP6 antibody; Anoplopoma fimbria CHMP6 antibody C3KIC8 93.0%
ARP65537 Sablefish CHMP6 antibody; Anoplopoma fimbria CHMP6 antibody C3KIC8 80.0%
ARP65537 Small-eared galago CHMP6 antibody; Otolemur garnettii CHMP6 antibody H0X2X4 100.0%
ARP65538 Small-eared galago CHMP6 antibody; Otolemur garnettii CHMP6 antibody H0X2X4 100.0%
ARP65537 Sumatran orangutan CHMP6 antibody; Pongo abelii CHMP6 antibody Q5R861 100.0%
ARP65538 Sumatran orangutan CHMP6 antibody; Pongo abelii CHMP6 antibody Q5R861 100.0%
ARP65537 Sumatran orangutan CHMP6 antibody; Pongo abelii CHMP6 antibody H2NV00 93.0%
ARP65538 Tasmanian devil CHMP6 antibody; Sarcophilus harrisii CHMP6 antibody G3W175 79.0%
ARP65537 Thirteen-lined ground squirrel CHMP6 antibody; Spermophilus tridecemlineatus CHMP6 antibody I3N4K9 100.0%
ARP65538 Thirteen-lined ground squirrel CHMP6 antibody; Spermophilus tridecemlineatus CHMP6 antibody I3N4K9 100.0%
ARP65537 Western clawed frog CHMP6 antibody; Xenopus tropicalis CHMP6 antibody A4QNP3 85.0%
ARP65537 White-tufted-ear marmoset CHMP6 antibody; Callithrix jacchus CHMP6 antibody U3BEI2 100.0%
ARP65538 White-tufted-ear marmoset CHMP6 antibody; Callithrix jacchus CHMP6 antibody U3BEI2 100.0%
ARP65538 Zebra finch CHMP6 antibody; Taeniopygia guttata CHMP6 antibody H0YXU4 92.0%
ARP65537 Zebra finch CHMP6 antibody; Taeniopygia guttata CHMP6 antibody H0YXU4 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas218743_at721_B_lymphoblasts17.00015.780Details
BioGPS Gene Atlas218743_atAdipocyte14.60015.780Details
BioGPS Gene Atlas218743_atAdrenalCortex16.60015.780Details
BioGPS Gene Atlas218743_atAdrenalgland10.75015.780Details
BioGPS Gene Atlas218743_atAmygdala13.45015.780Details
BioGPS Gene Atlas218743_atAppendix8.50015.780Details
BioGPS Gene Atlas218743_atAtrioventricularNode9.60015.780Details
BioGPS Gene Atlas218743_atBDCA4+_DentriticCells24.60015.780Details
BioGPS Gene Atlas218743_atBonemarrow12.30015.780Details
BioGPS Gene Atlas218743_atBronchialEpithelialCells14.20015.780Details
BioGPS Gene Atlas218743_atCD105+_Endothelial15.25015.780Details
BioGPS Gene Atlas218743_atCD14+_Monocytes25.10015.780Details
BioGPS Gene Atlas218743_atCD19+_BCells(neg._sel.)19.40015.780Details
BioGPS Gene Atlas218743_atCD33+_Myeloid21.90015.780Details
BioGPS Gene Atlas218743_atCD34+16.20015.780Details
BioGPS Gene Atlas218743_atCD4+_Tcells17.85015.780Details
BioGPS Gene Atlas218743_atCD56+_NKCells36.80015.780Details
BioGPS Gene Atlas218743_atCD71+_EarlyErythroid11.30015.780Details
BioGPS Gene Atlas218743_atCD8+_Tcells18.75015.780Details
BioGPS Gene Atlas218743_atCardiacMyocytes15.65015.780Details
BioGPS Gene Atlas218743_atCaudatenucleus11.05015.780Details
BioGPS Gene Atlas218743_atCerebellum9.85015.780Details
BioGPS Gene Atlas218743_atCerebellumPeduncles26.45015.780Details
BioGPS Gene Atlas218743_atCiliaryGanglion8.70015.780Details
BioGPS Gene Atlas218743_atCingulateCortex12.50015.780Details
BioGPS Gene Atlas218743_atColorectaladenocarcinoma12.60015.780Details
BioGPS Gene Atlas218743_atDorsalRootGanglion9.35015.780Details
BioGPS Gene Atlas218743_atFetalThyroid15.10015.780Details
BioGPS Gene Atlas218743_atFetalbrain11.60015.780Details
BioGPS Gene Atlas218743_atFetalliver10.75015.780Details
BioGPS Gene Atlas218743_atFetallung11.55015.780Details
BioGPS Gene Atlas218743_atGlobusPallidus9.10015.780Details
BioGPS Gene Atlas218743_atHeart72.65015.780Details
BioGPS Gene Atlas218743_atHypothalamus14.05015.780Details
BioGPS Gene Atlas218743_atKidney10.35015.780Details
BioGPS Gene Atlas218743_atLeukemia_chronicMyelogenousK-56211.35015.780Details
BioGPS Gene Atlas218743_atLeukemia_promyelocytic-HL-6010.75015.780Details
BioGPS Gene Atlas218743_atLeukemialymphoblastic(MOLT-4)14.70015.780Details
BioGPS Gene Atlas218743_atLiver36.15015.780Details
BioGPS Gene Atlas218743_atLung31.65015.780Details
BioGPS Gene Atlas218743_atLymphnode10.25015.780Details
BioGPS Gene Atlas218743_atLymphoma_burkitts(Daudi)15.95015.780Details
BioGPS Gene Atlas218743_atLymphoma_burkitts(Raji)17.15015.780Details
BioGPS Gene Atlas218743_atMedullaOblongata9.60015.780Details
BioGPS Gene Atlas218743_atOccipitalLobe11.35015.780Details
BioGPS Gene Atlas218743_atOlfactoryBulb10.45015.780Details
BioGPS Gene Atlas218743_atOvary7.70015.780Details
BioGPS Gene Atlas218743_atPancreas16.10015.780Details
BioGPS Gene Atlas218743_atPancreaticIslet13.00015.780Details
BioGPS Gene Atlas218743_atParietalLobe13.20015.780Details
BioGPS Gene Atlas218743_atPituitary14.70015.780Details
BioGPS Gene Atlas218743_atPlacenta32.20015.780Details
BioGPS Gene Atlas218743_atPons11.85015.780Details
BioGPS Gene Atlas218743_atPrefrontalCortex13.55015.780Details
BioGPS Gene Atlas218743_atProstate19.85015.780Details
BioGPS Gene Atlas218743_atSalivarygland9.80015.780Details
BioGPS Gene Atlas218743_atSkeletalMuscle18.65015.780Details
BioGPS Gene Atlas218743_atSkin10.10015.780Details
BioGPS Gene Atlas218743_atSmoothMuscle17.50015.780Details
BioGPS Gene Atlas218743_atSpinalcord13.50015.780Details
BioGPS Gene Atlas218743_atSubthalamicNucleus11.20015.780Details
BioGPS Gene Atlas218743_atSuperiorCervicalGanglion10.60015.780Details
BioGPS Gene Atlas218743_atTemporalLobe11.30015.780Details
BioGPS Gene Atlas218743_atTestis11.15015.780Details
BioGPS Gene Atlas218743_atTestisGermCell9.90015.780Details
BioGPS Gene Atlas218743_atTestisIntersitial10.30015.780Details
BioGPS Gene Atlas218743_atTestisLeydigCell10.05015.780Details
BioGPS Gene Atlas218743_atTestisSeminiferousTubule10.90015.780Details
BioGPS Gene Atlas218743_atThalamus14.90015.780Details
BioGPS Gene Atlas218743_atThymus10.10015.780Details
BioGPS Gene Atlas218743_atThyroid20.30015.780Details
BioGPS Gene Atlas218743_atTongue15.35015.780Details
BioGPS Gene Atlas218743_atTonsil12.20015.780Details
BioGPS Gene Atlas218743_atTrachea10.60015.780Details
BioGPS Gene Atlas218743_atTrigeminalGanglion12.55015.780Details
BioGPS Gene Atlas218743_atUterus12.95015.780Details
BioGPS Gene Atlas218743_atUterusCorpus18.75015.780Details
BioGPS Gene Atlas218743_atWholeBlood15.65015.780Details
BioGPS Gene Atlas218743_atWholebrain10.90015.780Details
BioGPS Gene Atlas218743_atcolon11.85015.780Details
BioGPS Gene Atlas218743_atpineal_day16.92015.780Details
BioGPS Gene Atlas218743_atpineal_night15.40015.780Details
BioGPS Gene Atlas218743_atretina34.57515.780Details
BioGPS Gene Atlas218743_atsmall_intestine10.30015.780Details
BioGPS NCI60218743_at78679.63661.640Details
BioGPS NCI60218743_atA172115.75561.640Details
BioGPS NCI60218743_atA20443.98961.640Details
BioGPS NCI60218743_atA36144.72861.640Details
BioGPS NCI60218743_atA49847.38761.640Details
BioGPS NCI60218743_atA54944.91961.640Details
BioGPS NCI60218743_atACC332.95561.640Details
BioGPS NCI60218743_atACHN66.65261.640Details
BioGPS NCI60218743_atALVA3145.39561.640Details
BioGPS NCI60218743_atCAKI163.25061.640Details
BioGPS NCI60218743_atCCRT CEM50.28461.640Details
BioGPS NCI60218743_atCOLO20544.53761.640Details
BioGPS NCI60218743_atDLD146.97361.640Details
BioGPS NCI60218743_atDU14546.01461.640Details
BioGPS NCI60218743_atEKVX51.52961.640Details
BioGPS NCI60218743_atGM13347.74961.640Details
BioGPS NCI60218743_atGM160060.41161.640Details
BioGPS NCI60218743_atGM231347.52261.640Details
BioGPS NCI60218743_atGM234550.46161.640Details
BioGPS NCI60218743_atGM249347.88161.640Details
BioGPS NCI60218743_atGM9750.48761.640Details
BioGPS NCI60218743_atHCC299818.08861.640Details
BioGPS NCI60218743_atHCT11645.53561.640Details
BioGPS NCI60218743_atHCT1522.73861.640Details
BioGPS NCI60218743_atHEK 293 T-rex47.31061.640Details
BioGPS NCI60218743_atHEK 293T46.23661.640Details
BioGPS NCI60218743_atHEK29376.92761.640Details
BioGPS NCI60218743_atHELA38.85961.640Details
BioGPS NCI60218743_atHEPG247.28661.640Details
BioGPS NCI60218743_atHL6046.07661.640Details
BioGPS NCI60218743_atHOP6283.32261.640Details
BioGPS NCI60218743_atHOP92136.35261.640Details
BioGPS NCI60218743_atHS578T76.37761.640Details
BioGPS NCI60218743_atHSG43.59361.640Details
BioGPS NCI60218743_atHT108012.94661.640Details
BioGPS NCI60218743_atHT2945.94361.640Details
BioGPS NCI60218743_atIGROV146.90661.640Details
BioGPS NCI60218743_atIOSE80131.14061.640Details
BioGPS NCI60218743_atJURKAT44.32061.640Details
BioGPS NCI60218743_atK56245.67661.640Details
BioGPS NCI60218743_atKM1245.24961.640Details
BioGPS NCI60218743_atLN1853.34661.640Details
BioGPS NCI60218743_atLNCAP47.10261.640Details
BioGPS NCI60218743_atLOX IMVI113.80561.640Details
BioGPS NCI60218743_atM1435.48861.640Details
BioGPS NCI60218743_atMALME 3M45.71661.640Details
BioGPS NCI60218743_atMCF741.63561.640Details
BioGPS NCI60218743_atMD MB23147.61061.640Details
BioGPS NCI60218743_atMDA MB43579.09361.640Details
BioGPS NCI60218743_atMOLT4109.99161.640Details
BioGPS NCI60218743_atNCI 46045.00961.640Details
BioGPS NCI60218743_atNCI H22650.95561.640Details
BioGPS NCI60218743_atNCI H2347.33961.640Details
BioGPS NCI60218743_atNCI H322M44.59161.640Details
BioGPS NCI60218743_atNCVADR RES20.81361.640Details
BioGPS NCI60218743_atOVCAR3122.90361.640Details
BioGPS NCI60218743_atOVCAR444.26561.640Details
BioGPS NCI60218743_atOVCAR544.02961.640Details
BioGPS NCI60218743_atOVCAR846.06961.640Details
BioGPS NCI60218743_atPANC151.75261.640Details
BioGPS NCI60218743_atRL715.62261.640Details
BioGPS NCI60218743_atRPMI 822639.69961.640Details
BioGPS NCI60218743_atRS1184645.32661.640Details
BioGPS NCI60218743_atRXF39347.21561.640Details
BioGPS NCI60218743_atSAOS235.35861.640Details
BioGPS NCI60218743_atSF26862.86361.640Details
BioGPS NCI60218743_atSF295182.66761.640Details
BioGPS NCI60218743_atSF53945.73861.640Details
BioGPS NCI60218743_atSHSYSY+RA43.52661.640Details
BioGPS NCI60218743_atSHSYSY-RA70.66361.640Details
BioGPS NCI60218743_atSKMEL247.39061.640Details
BioGPS NCI60218743_atSKMEL2844.27761.640Details
BioGPS NCI60218743_atSKMEL599.12661.640Details
BioGPS NCI60218743_atSKOV348.20961.640Details
BioGPS NCI60218743_atSN12C47.39861.640Details
BioGPS NCI60218743_atSNB1994.31661.640Details
BioGPS NCI60218743_atSNB7547.06661.640Details
BioGPS NCI60218743_atSR47.67161.640Details
BioGPS NCI60218743_atSW62047.06761.640Details
BioGPS NCI60218743_atT2448.15561.640Details
BioGPS NCI60218743_atT3M445.22461.640Details
BioGPS NCI60218743_atTK1047.07361.640Details
BioGPS NCI60218743_atU118134.01161.640Details
BioGPS NCI60218743_atU138201.45861.640Details
BioGPS NCI60218743_atU20S164.56561.640Details
BioGPS NCI60218743_atU25154.86061.640Details
BioGPS NCI60218743_atU8763.11461.640Details
BioGPS NCI60218743_atUACC25746.88861.640Details
BioGPS NCI60218743_atUACC6238.50361.640Details
BioGPS NCI60218743_atUO3146.98361.640Details
BioGPS NCI60218743_atZR75_144.88461.640Details
BioGPS NCI60218743_atastrocytes53.00761.640Details
BioGPS NCI60218743_athuh-745.41061.640Details