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Gene ID: 27243 | CHMP2A Antibody Resource


CHMP2A Antibody Resource
Gene Full Name: 
charged multivesicular body protein 2A
Uniprot: 
O43633
Protein Name: 
charged multivesicular body protein 2a
Nucleotide: 
XM_005258746
Alias: 
BC2;BC-2;VPS2;CHMP2;VPS2A;
Ensembl: 
ENSG00000130724
Location: 
19q
HPRD: 
12520
NCBI Gene: 
27243
MIM: 
610893

Summary: 
CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]
Function: 
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.
Subcellular location: 
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note: Localizes to the midbody of dividing cells. Localized in two distinct rings on either side of the Fleming body.
PTM: 
Acetylation;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Protein OPPA01396 CHMP2A Human - Recombinant Human Chromatin Modifying Protein 2A (5ug) 5ug $100 Details
Polyclonal Antibody ARP62112_P050 CHMP2A antibody - C-terminal region (ARP62112_P050) Bovine, Dog, Horse, Rat WB 50ug $289 Details
Polyclonal Antibody ARP62111_P050 CHMP2A antibody - N-terminal region (ARP62111_P050) Bovine, Dog, Rat WB 50ug $289 Details

Show all CHMP2A antibodies


Product Images
CHMP2A antibody - N-terminal region (ARP62111_P050) in Human Fetal Lung cells using Western Blot

Sample Type: Human Fetal Lung

CHMP2A antibody - C-terminal region (ARP62112_P050) in Human 293T cells using Western Blot

Sample Type: Human 293T

CHMP2A antibody - C-terminal region (ARP62112_P050) in Human 721_B cells using Western Blot

Sample Type: Human 721_B


CHMP2A Protocols
Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP62111 African clawed frog CHMP2A antibody; Xenopus laevis CHMP2A antibody Q6IP52 100.0%
ARP62111 Atlantic salmon CHMP2A antibody; Salmo salar CHMP2A antibody B3TDD9 100.0%
ARP62112 Atlantic salmon CHMP2A antibody; Salmo salar CHMP2A antibody B3TDD9 92.0%
ARP62111 Bovine CHMP2A antibody; Bos taurus CHMP2A antibody Q3T0U5 100.0%
ARP62112 Bovine CHMP2A antibody; Bos taurus CHMP2A antibody Q3T0U5 100.0%
ARP62111 Cat CHMP2A antibody; Felis catus CHMP2A antibody M3W0W8 100.0%
ARP62112 Cat CHMP2A antibody; Felis catus CHMP2A antibody M3W0W8 93.0%
ARP62111 Chicken CHMP2A antibody; Gallus gallus CHMP2A antibody Q5ZHN1 100.0%
ARP62111 Chimpanzee CHMP2A antibody; Pan troglodytes CHMP2A antibody H2QHC5 100.0%
ARP62112 Chimpanzee CHMP2A antibody; Pan troglodytes CHMP2A antibody H2QHC5 100.0%
ARP62111 Chimpanzee CHMP2A antibody; Pan troglodytes CHMP2A antibody K7B1F5 100.0%
ARP62112 Chimpanzee CHMP2A antibody; Pan troglodytes CHMP2A antibody K7B1F5 100.0%
ARP62111 Chinese softshell turtle CHMP2A antibody; Pelodiscus sinensis CHMP2A antibody K7GBU9 100.0%
ARP62111 Collared flycatcher CHMP2A antibody; Ficedula albicollis CHMP2A antibody U3KEF1 100.0%
ARP62111 Dog CHMP2A antibody; Canis familiaris CHMP2A antibody E2RIU2 100.0%
ARP62112 Dog CHMP2A antibody; Canis familiaris CHMP2A antibody E2RIU2 93.0%
ARP62111 European domestic ferret CHMP2A antibody; Mustela putorius furo CHMP2A antibody M3YA47 100.0%
ARP62112 European domestic ferret CHMP2A antibody; Mustela putorius furo CHMP2A antibody M3YA47 93.0%
ARP62111 European seabass CHMP2A antibody; Dicentrarchus labrax CHMP2A antibody E6ZI34 100.0%
ARP62112 Horse CHMP2A antibody; Equus caballus CHMP2A antibody F6PUX8 93.0%
ARP62111 Human CHMP2A antibody; Homo sapiens CHMP2A antibody M0QXX8 100.0%
ARP62111 Human CHMP2A antibody; Homo sapiens CHMP2A antibody M0R1L7 100.0%
ARP62111 Human CHMP2A antibody; Homo sapiens CHMP2A antibody M0R1T5 100.0%
ARP62112 Human CHMP2A antibody; Homo sapiens CHMP2A antibody M0R1T5 100.0%
ARP62111 Human CHMP2A antibody; Homo sapiens CHMP2A antibody O43633 100.0%
ARP62112 Human CHMP2A antibody; Homo sapiens CHMP2A antibody O43633 100.0%
ARP62111 Hydra CHMP2A antibody; Hydra vulgaris CHMP2A antibody T2MIL9 92.0%
ARP62111 Mouse CHMP2A antibody; Mus musculus CHMP2A antibody Q9DB34 100.0%
ARP62112 Mouse CHMP2A antibody; Mus musculus CHMP2A antibody Q9DB34 100.0%
ARP62112 Pig CHMP2A antibody; Sus scrofa CHMP2A antibody I3LSS2 93.0%
ARP62111 Rabbit CHMP2A antibody; Oryctolagus cuniculus CHMP2A antibody G1TC07 100.0%
ARP62112 Rabbit CHMP2A antibody; Oryctolagus cuniculus CHMP2A antibody G1TC07 100.0%
ARP62111 Rat CHMP2A antibody; Rattus norvegicus CHMP2A antibody B2RZB5 100.0%
ARP62112 Rat CHMP2A antibody; Rattus norvegicus CHMP2A antibody B2RZB5 100.0%
ARP62111 Rhesus macaque CHMP2A antibody; Macaca mulatta CHMP2A antibody F7HNZ9 100.0%
ARP62112 Rhesus macaque CHMP2A antibody; Macaca mulatta CHMP2A antibody F7HNZ9 100.0%
ARP62111 Small-eared galago CHMP2A antibody; Otolemur garnettii CHMP2A antibody H0WSG9 100.0%
ARP62112 Small-eared galago CHMP2A antibody; Otolemur garnettii CHMP2A antibody H0WSG9 100.0%
ARP62111 Spotted green pufferfish CHMP2A antibody; Tetraodon nigroviridis CHMP2A antibody Q4SFE2 100.0%
ARP62112 Spotted green pufferfish CHMP2A antibody; Tetraodon nigroviridis CHMP2A antibody Q4SFE2 92.0%
ARP62111 Sumatran orangutan CHMP2A antibody; Pongo abelii CHMP2A antibody H2P0H8 100.0%
ARP62112 Sumatran orangutan CHMP2A antibody; Pongo abelii CHMP2A antibody H2P0H8 100.0%
ARP62111 Tasmanian devil CHMP2A antibody; Sarcophilus harrisii CHMP2A antibody G3VR36 100.0%
ARP62112 Tasmanian devil CHMP2A antibody; Sarcophilus harrisii CHMP2A antibody G3VR36 100.0%
ARP62111 Western clawed frog CHMP2A antibody; Xenopus tropicalis CHMP2A antibody Q6DFS6 100.0%
ARP62111 White-tufted-ear marmoset CHMP2A antibody; Callithrix jacchus CHMP2A antibody F6RTE8 100.0%
ARP62112 White-tufted-ear marmoset CHMP2A antibody; Callithrix jacchus CHMP2A antibody F6RTE8 100.0%
ARP62111 White-tufted-ear marmoset CHMP2A antibody; Callithrix jacchus CHMP2A antibody U3BCA1 100.0%
ARP62112 White-tufted-ear marmoset CHMP2A antibody; Callithrix jacchus CHMP2A antibody U3BCA1 100.0%
ARP62111 Zebrafish CHMP2A antibody; Danio rerio CHMP2A antibody Q7ZW25 100.0%
ARP62112 Zebrafish CHMP2A antibody; Danio rerio CHMP2A antibody Q7ZW25 92.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas202121_s_at721_B_lymphoblasts909.350295.770Details
BioGPS Gene Atlas202121_s_atAdipocyte159.950295.770Details
BioGPS Gene Atlas202121_s_atAdrenalCortex140.650295.770Details
BioGPS Gene Atlas202121_s_atAdrenalgland212.750295.770Details
BioGPS Gene Atlas202121_s_atAmygdala231.550295.770Details
BioGPS Gene Atlas202121_s_atAppendix64.000295.770Details
BioGPS Gene Atlas202121_s_atAtrioventricularNode44.250295.770Details
BioGPS Gene Atlas202121_s_atBDCA4+_DentriticCells600.900295.770Details
BioGPS Gene Atlas202121_s_atBonemarrow162.950295.770Details
BioGPS Gene Atlas202121_s_atBronchialEpithelialCells347.300295.770Details
BioGPS Gene Atlas202121_s_atCD105+_Endothelial373.400295.770Details
BioGPS Gene Atlas202121_s_atCD14+_Monocytes1172.800295.770Details
BioGPS Gene Atlas202121_s_atCD19+_BCells(neg._sel.)448.000295.770Details
BioGPS Gene Atlas202121_s_atCD33+_Myeloid1002.900295.770Details
BioGPS Gene Atlas202121_s_atCD34+440.700295.770Details
BioGPS Gene Atlas202121_s_atCD4+_Tcells300.100295.770Details
BioGPS Gene Atlas202121_s_atCD56+_NKCells745.200295.770Details
BioGPS Gene Atlas202121_s_atCD71+_EarlyErythroid990.750295.770Details
BioGPS Gene Atlas202121_s_atCD8+_Tcells257.850295.770Details
BioGPS Gene Atlas202121_s_atCardiacMyocytes257.000295.770Details
BioGPS Gene Atlas202121_s_atCaudatenucleus161.200295.770Details
BioGPS Gene Atlas202121_s_atCerebellum85.750295.770Details
BioGPS Gene Atlas202121_s_atCerebellumPeduncles117.100295.770Details
BioGPS Gene Atlas202121_s_atCiliaryGanglion20.300295.770Details
BioGPS Gene Atlas202121_s_atCingulateCortex151.750295.770Details
BioGPS Gene Atlas202121_s_atColorectaladenocarcinoma537.800295.770Details
BioGPS Gene Atlas202121_s_atDorsalRootGanglion52.250295.770Details
BioGPS Gene Atlas202121_s_atFetalThyroid219.400295.770Details
BioGPS Gene Atlas202121_s_atFetalbrain124.850295.770Details
BioGPS Gene Atlas202121_s_atFetalliver115.450295.770Details
BioGPS Gene Atlas202121_s_atFetallung147.900295.770Details
BioGPS Gene Atlas202121_s_atGlobusPallidus75.550295.770Details
BioGPS Gene Atlas202121_s_atHeart513.100295.770Details
BioGPS Gene Atlas202121_s_atHypothalamus227.100295.770Details
BioGPS Gene Atlas202121_s_atKidney155.300295.770Details
BioGPS Gene Atlas202121_s_atLeukemia_chronicMyelogenousK-562136.650295.770Details
BioGPS Gene Atlas202121_s_atLeukemia_promyelocytic-HL-60135.700295.770Details
BioGPS Gene Atlas202121_s_atLeukemialymphoblastic(MOLT-4)101.150295.770Details
BioGPS Gene Atlas202121_s_atLiver566.750295.770Details
BioGPS Gene Atlas202121_s_atLung519.300295.770Details
BioGPS Gene Atlas202121_s_atLymphnode118.350295.770Details
BioGPS Gene Atlas202121_s_atLymphoma_burkitts(Daudi)68.400295.770Details
BioGPS Gene Atlas202121_s_atLymphoma_burkitts(Raji)243.450295.770Details
BioGPS Gene Atlas202121_s_atMedullaOblongata109.000295.770Details
BioGPS Gene Atlas202121_s_atOccipitalLobe132.750295.770Details
BioGPS Gene Atlas202121_s_atOlfactoryBulb135.650295.770Details
BioGPS Gene Atlas202121_s_atOvary113.450295.770Details
BioGPS Gene Atlas202121_s_atPancreas109.800295.770Details
BioGPS Gene Atlas202121_s_atPancreaticIslet367.200295.770Details
BioGPS Gene Atlas202121_s_atParietalLobe140.550295.770Details
BioGPS Gene Atlas202121_s_atPituitary179.500295.770Details
BioGPS Gene Atlas202121_s_atPlacenta233.750295.770Details
BioGPS Gene Atlas202121_s_atPons83.950295.770Details
BioGPS Gene Atlas202121_s_atPrefrontalCortex285.700295.770Details
BioGPS Gene Atlas202121_s_atProstate487.200295.770Details
BioGPS Gene Atlas202121_s_atSalivarygland152.250295.770Details
BioGPS Gene Atlas202121_s_atSkeletalMuscle100.250295.770Details
BioGPS Gene Atlas202121_s_atSkin110.250295.770Details
BioGPS Gene Atlas202121_s_atSmoothMuscle368.650295.770Details
BioGPS Gene Atlas202121_s_atSpinalcord240.800295.770Details
BioGPS Gene Atlas202121_s_atSubthalamicNucleus100.400295.770Details
BioGPS Gene Atlas202121_s_atSuperiorCervicalGanglion51.100295.770Details
BioGPS Gene Atlas202121_s_atTemporalLobe125.350295.770Details
BioGPS Gene Atlas202121_s_atTestis211.800295.770Details
BioGPS Gene Atlas202121_s_atTestisGermCell132.850295.770Details
BioGPS Gene Atlas202121_s_atTestisIntersitial118.400295.770Details
BioGPS Gene Atlas202121_s_atTestisLeydigCell110.350295.770Details
BioGPS Gene Atlas202121_s_atTestisSeminiferousTubule105.200295.770Details
BioGPS Gene Atlas202121_s_atThalamus176.600295.770Details
BioGPS Gene Atlas202121_s_atThymus208.650295.770Details
BioGPS Gene Atlas202121_s_atThyroid584.550295.770Details
BioGPS Gene Atlas202121_s_atTongue116.200295.770Details
BioGPS Gene Atlas202121_s_atTonsil105.500295.770Details
BioGPS Gene Atlas202121_s_atTrachea117.900295.770Details
BioGPS Gene Atlas202121_s_atTrigeminalGanglion26.150295.770Details
BioGPS Gene Atlas202121_s_atUterus171.700295.770Details
BioGPS Gene Atlas202121_s_atUterusCorpus91.300295.770Details
BioGPS Gene Atlas202121_s_atWholeBlood931.750295.770Details
BioGPS Gene Atlas202121_s_atWholebrain375.450295.770Details
BioGPS Gene Atlas202121_s_atcolon599.150295.770Details
BioGPS Gene Atlas202121_s_atpineal_day651.080295.770Details
BioGPS Gene Atlas202121_s_atpineal_night623.180295.770Details
BioGPS Gene Atlas202121_s_atretina484.900295.770Details
BioGPS Gene Atlas202121_s_atsmall_intestine604.050295.770Details
BioGPS NCI60202121_s_at7861438.4832281.380Details
BioGPS NCI60202121_s_atA172988.9092281.380Details
BioGPS NCI60202121_s_atA2041352.7012281.380Details
BioGPS NCI60202121_s_atA3613753.0902281.380Details
BioGPS NCI60202121_s_atA4982090.2112281.380Details
BioGPS NCI60202121_s_atA5493414.7372281.380Details
BioGPS NCI60202121_s_atACC32468.9012281.380Details
BioGPS NCI60202121_s_atACHN2136.2152281.380Details
BioGPS NCI60202121_s_atALVA313052.9522281.380Details
BioGPS NCI60202121_s_atCAKI12322.0992281.380Details
BioGPS NCI60202121_s_atCCRT CEM467.4472281.380Details
BioGPS NCI60202121_s_atCOLO2054121.7652281.380Details
BioGPS NCI60202121_s_atDLD11790.3472281.380Details
BioGPS NCI60202121_s_atDU1451383.4072281.380Details
BioGPS NCI60202121_s_atEKVX3150.5742281.380Details
BioGPS NCI60202121_s_atGM133951.8072281.380Details
BioGPS NCI60202121_s_atGM16002993.4182281.380Details
BioGPS NCI60202121_s_atGM23131765.2862281.380Details
BioGPS NCI60202121_s_atGM23453784.9062281.380Details
BioGPS NCI60202121_s_atGM24931825.2562281.380Details
BioGPS NCI60202121_s_atGM972257.2012281.380Details
BioGPS NCI60202121_s_atHCC29983492.9322281.380Details
BioGPS NCI60202121_s_atHCT1162644.2412281.380Details
BioGPS NCI60202121_s_atHCT155554.4782281.380Details
BioGPS NCI60202121_s_atHEK 293 T-rex574.2932281.380Details
BioGPS NCI60202121_s_atHEK 293T1087.3692281.380Details
BioGPS NCI60202121_s_atHEK2931054.5752281.380Details
BioGPS NCI60202121_s_atHELA3013.5682281.380Details
BioGPS NCI60202121_s_atHEPG2593.7712281.380Details
BioGPS NCI60202121_s_atHL60510.7342281.380Details
BioGPS NCI60202121_s_atHOP621049.2902281.380Details
BioGPS NCI60202121_s_atHOP921068.3972281.380Details
BioGPS NCI60202121_s_atHS578T1533.4582281.380Details
BioGPS NCI60202121_s_atHSG2518.3402281.380Details
BioGPS NCI60202121_s_atHT10802342.8772281.380Details
BioGPS NCI60202121_s_atHT292931.2082281.380Details
BioGPS NCI60202121_s_atIGROV13132.8962281.380Details
BioGPS NCI60202121_s_atIOSE801265.0712281.380Details
BioGPS NCI60202121_s_atJURKAT1461.6822281.380Details
BioGPS NCI60202121_s_atK562860.4172281.380Details
BioGPS NCI60202121_s_atKM121907.8842281.380Details
BioGPS NCI60202121_s_atLN185222.7972281.380Details
BioGPS NCI60202121_s_atLNCAP3872.9072281.380Details
BioGPS NCI60202121_s_atLOX IMVI1925.6822281.380Details
BioGPS NCI60202121_s_atM141263.0902281.380Details
BioGPS NCI60202121_s_atMALME 3M1186.9742281.380Details
BioGPS NCI60202121_s_atMCF72217.5682281.380Details
BioGPS NCI60202121_s_atMD MB2311503.1632281.380Details
BioGPS NCI60202121_s_atMDA MB4351806.1662281.380Details
BioGPS NCI60202121_s_atMOLT42148.6282281.380Details
BioGPS NCI60202121_s_atNCI 4602984.2902281.380Details
BioGPS NCI60202121_s_atNCI H2261656.4232281.380Details
BioGPS NCI60202121_s_atNCI H231572.1452281.380Details
BioGPS NCI60202121_s_atNCI H322M2612.1752281.380Details
BioGPS NCI60202121_s_atNCVADR RES2182.7482281.380Details
BioGPS NCI60202121_s_atOVCAR31802.2712281.380Details
BioGPS NCI60202121_s_atOVCAR44579.8022281.380Details
BioGPS NCI60202121_s_atOVCAR51826.4022281.380Details
BioGPS NCI60202121_s_atOVCAR81019.6572281.380Details
BioGPS NCI60202121_s_atPANC15591.4302281.380Details
BioGPS NCI60202121_s_atRL71909.3652281.380Details
BioGPS NCI60202121_s_atRPMI 82263297.5482281.380Details
BioGPS NCI60202121_s_atRS118461265.6122281.380Details
BioGPS NCI60202121_s_atRXF393629.2602281.380Details
BioGPS NCI60202121_s_atSAOS2415.6872281.380Details
BioGPS NCI60202121_s_atSF2681171.2252281.380Details
BioGPS NCI60202121_s_atSF2952007.2012281.380Details
BioGPS NCI60202121_s_atSF5391393.4212281.380Details
BioGPS NCI60202121_s_atSHSYSY+RA3903.0942281.380Details
BioGPS NCI60202121_s_atSHSYSY-RA4409.1682281.380Details
BioGPS NCI60202121_s_atSKMEL22162.3212281.380Details
BioGPS NCI60202121_s_atSKMEL283631.2242281.380Details
BioGPS NCI60202121_s_atSKMEL52347.3082281.380Details
BioGPS NCI60202121_s_atSKOV32699.7092281.380Details
BioGPS NCI60202121_s_atSN12C3982.6602281.380Details
BioGPS NCI60202121_s_atSNB192126.1502281.380Details
BioGPS NCI60202121_s_atSNB751258.3862281.380Details
BioGPS NCI60202121_s_atSR2562.9122281.380Details
BioGPS NCI60202121_s_atSW620797.2132281.380Details
BioGPS NCI60202121_s_atT241927.4692281.380Details
BioGPS NCI60202121_s_atT3M43447.4662281.380Details
BioGPS NCI60202121_s_atTK101561.7312281.380Details
BioGPS NCI60202121_s_atU1183767.5902281.380Details
BioGPS NCI60202121_s_atU1387681.8522281.380Details
BioGPS NCI60202121_s_atU20S232.8112281.380Details
BioGPS NCI60202121_s_atU2512061.2742281.380Details
BioGPS NCI60202121_s_atU873393.4252281.380Details
BioGPS NCI60202121_s_atUACC2573503.4352281.380Details
BioGPS NCI60202121_s_atUACC624251.6782281.380Details
BioGPS NCI60202121_s_atUO311359.5902281.380Details
BioGPS NCI60202121_s_atZR75_13688.5392281.380Details
BioGPS NCI60202121_s_atastrocytes1644.7582281.380Details
BioGPS NCI60202121_s_athuh-7392.0392281.380Details