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Gene ID: 27159 | CHIA Antibody Resource


CHIA Antibody Resource
Gene Full Name: 
chitinase, acidic
Uniprot: 
Q9BZP6
Protein Name: 
acidic mammalian chitinase
Nucleotide: 
NM_201653
Alias: 
CHIT2;AMCASE;TSA1902;
Ensembl: 
ENSG00000134216
Location: 
1p13.2
HPRD: 
09355
NCBI Gene: 
27159
MIM: 
606080

Summary: 
The protein encoded by this gene degrades chitin, which is found in the cell wall of most fungi as well as in arthropods and some nematodes. The encoded protein can also stimulate interleukin 13 expression, and variations in this gene can lead to asthma susceptibility. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Function: 
Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding.
Subcellular location: 
Isoform 1: Secreted. Note: Secretion depends on EGFR activity. Isoform 2: Cytoplasm . Isoform 3: Cytoplasm .
PTM: 
Disulfide bond;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP42602_P050 CHIA antibody - middle region (ARP42602_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Rat WB 50ug $289 Details
Polyclonal Antibody ARP42601_P050 CHIA antibody - N-terminal region (ARP42601_P050) Polyclonal Bovine, Dog, Human, Mouse, Rat, Zebrafish WB 50ug $289 Details
Polyclonal Antibody OAAB05987 CHIA antibody - N-terminal region (OAAB05987) Human; Mouse WB, FC, ELISA 400ul $289 Details

Show all CHIA antibodies


Product Images
CHIA antibody - N-terminal region (ARP42601_P050) in Hum. Fetal Heart cells using Western Blot

Sample Type: Hum. Fetal Heart

CHIA antibody - N-terminal region (ARP42601_P050) in Hum. Fetal Liver cells using Western Blot

Sample Type: Hum. Fetal Liver

CHIA antibody - N-terminal region (ARP42601_P050) in Hum. Fetal Lung cells using Western Blot

Sample Type: Hum. Fetal Lung

CHIA antibody - N-terminal region (ARP42601_P050) in Transfected 293T cells using Western Blot

Sample Type: Transfected 293T

CHIA antibody - middle region (ARP42602_P050) in Human HeLa cells using Western Blot

Sample Type: Human HeLa

CHIA antibody - N-terminal region (OAAB05987) in Mouse Liver cells using Western Blot

Sample Type: Mouse Liver

CHIA antibody - N-terminal region (OAAB05987) in ZR-75-1 cells using Flow Cytometry

Sample Type: ZR-75-1


CHIA Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP42602 Bovine CHIA antibody; Bos taurus CHIA antibody F1MH27 100.0%
ARP42602 Bovine CHIA antibody; Bos taurus CHIA antibody Q95M17 100.0%
ARP42601 Bovine CHIA antibody; Bos taurus CHIA antibody F1MH27 93.0%
ARP42601 Bovine CHIA antibody; Bos taurus CHIA antibody Q95M17 86.0%
ARP42602 Cat CHIA antibody; Felis catus CHIA antibody M3X2K0 93.0%
ARP42601 Cat CHIA antibody; Felis catus CHIA antibody M3X2K0 86.0%
ARP42601 Chicken CHIA antibody; Gallus gallus CHIA antibody F1NM31 92.0%
ARP42601 Chicken CHIA antibody; Gallus gallus CHIA antibody F1NMM2 92.0%
ARP42602 Chicken CHIA antibody; Gallus gallus CHIA antibody F1NMM2 85.0%
ARP42601 Chinese softshell turtle CHIA antibody; Pelodiscus sinensis CHIA antibody K7FXD5 92.0%
ARP42601 Chinese softshell turtle CHIA antibody; Pelodiscus sinensis CHIA antibody K7FXF0 92.0%
ARP42602 Chinese softshell turtle CHIA antibody; Pelodiscus sinensis CHIA antibody K7FXD5 86.0%
ARP42602 Chinese softshell turtle CHIA antibody; Pelodiscus sinensis CHIA antibody K7FXF0 86.0%
ARP42601 Dog CHIA antibody; Canis familiaris CHIA antibody E2R8B1 100.0%
ARP42602 Dog CHIA antibody; Canis familiaris CHIA antibody E2R8B1 93.0%
ARP42601 European domestic ferret CHIA antibody; Mustela putorius furo CHIA antibody M3XYX0 86.0%
ARP42602 Horse CHIA antibody; Equus caballus CHIA antibody F6RHI6 86.0%
ARP42601 Human CHIA antibody; Homo sapiens CHIA antibody H7BXH6 100.0%
ARP42601 Human CHIA antibody; Homo sapiens CHIA antibody Q9BZP6 100.0%
ARP42602 Human CHIA antibody; Homo sapiens CHIA antibody Q9BZP6 100.0%
ARP42601 Human CHIA antibody; Homo sapiens CHIA antibody A5D6V7 100.0%
ARP42602 Human CHIA antibody; Homo sapiens CHIA antibody A5D6V7 100.0%
ARP42602 Human CHIA antibody; Homo sapiens CHIA antibody E9PLJ2 100.0%
ARP42601 Human CHIA antibody; Homo sapiens CHIA antibody Q5VUV5 100.0%
ARP42602 Human CHIA antibody; Homo sapiens CHIA antibody Q5VUV5 100.0%
ARP42601 Human CHIA antibody; Homo sapiens CHIA antibody Q9BZP6-2 100.0%
ARP42602 Human CHIA antibody; Homo sapiens CHIA antibody Q9BZP6-2 100.0%
ARP42602 Human CHIA antibody; Homo sapiens CHIA antibody Q9BZP6-3 100.0%
ARP42601 Mouse CHIA antibody; Mus musculus CHIA antibody A0T468 100.0%
ARP42601 Mouse CHIA antibody; Mus musculus CHIA antibody B8K282 100.0%
ARP42601 Mouse CHIA antibody; Mus musculus CHIA antibody D3Z1S6 100.0%
ARP42601 Mouse CHIA antibody; Mus musculus CHIA antibody Q91XA9 100.0%
ARP42602 Mouse CHIA antibody; Mus musculus CHIA antibody A0T468 93.0%
ARP42602 Mouse CHIA antibody; Mus musculus CHIA antibody B8K282 93.0%
ARP42602 Mouse CHIA antibody; Mus musculus CHIA antibody D3Z1S6 93.0%
ARP42602 Mouse CHIA antibody; Mus musculus CHIA antibody Q91XA9 93.0%
ARP42601 Northern white-cheeked gibbon CHIA antibody; Nomascus leucogenys CHIA antibody G1QUR7 100.0%
ARP42602 Northern white-cheeked gibbon CHIA antibody; Nomascus leucogenys CHIA antibody G1QUR7 92.0%
ARP42602 Pig CHIA antibody; Sus scrofa CHIA antibody I3LL32 100.0%
ARP42601 Pig CHIA antibody; Sus scrofa CHIA antibody I3LL32 93.0%
ARP47966 Rat CHIA antibody; Rattus norvegicus CHIA antibody Q4G094 100.0%
ARP47967 Rat CHIA antibody; Rattus norvegicus CHIA antibody Q4G094 100.0%
ARP42601 Rat CHIA antibody; Rattus norvegicus CHIA antibody F1LPK5 100.0%
ARP51214 Rat CHIA antibody; Rattus norvegicus CHIA antibody Q4G094 100.0%
ARP59011 Rat CHIA antibody; Rattus norvegicus CHIA antibody Q4G094 100.0%
ARP59012 Rat CHIA antibody; Rattus norvegicus CHIA antibody Q4G094 100.0%
ARP42601 Rat CHIA antibody; Rattus norvegicus CHIA antibody Q6RY07 100.0%
ARP42602 Rat CHIA antibody; Rattus norvegicus CHIA antibody F1LPK5 86.0%
ARP42602 Rat CHIA antibody; Rattus norvegicus CHIA antibody Q6RY07 86.0%
ARP42602 Small-eared galago CHIA antibody; Otolemur garnettii CHIA antibody H0X3H4 100.0%
ARP42601 Small-eared galago CHIA antibody; Otolemur garnettii CHIA antibody H0X3H4 93.0%
ARP42601 Sumatran orangutan CHIA antibody; Pongo abelii CHIA antibody H2N6E3 100.0%
ARP42602 Sumatran orangutan CHIA antibody; Pongo abelii CHIA antibody H2N6E3 100.0%
ARP42601 Thirteen-lined ground squirrel CHIA antibody; Spermophilus tridecemlineatus CHIA antibody I3M6A4 85.0%
ARP42601 Western clawed frog CHIA antibody; Xenopus tropicalis CHIA antibody Q5CZZ2 93.0%
ARP42601 Western clawed frog CHIA antibody; Xenopus tropicalis CHIA antibody F6RI40 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas220630_s_at721_B_lymphoblasts7.1006.570Details
BioGPS Gene Atlas220630_s_atAdipocyte6.4006.570Details
BioGPS Gene Atlas220630_s_atAdrenalCortex7.1506.570Details
BioGPS Gene Atlas220630_s_atAdrenalgland5.4506.570Details
BioGPS Gene Atlas220630_s_atAmygdala6.6506.570Details
BioGPS Gene Atlas220630_s_atAppendix6.9006.570Details
BioGPS Gene Atlas220630_s_atAtrioventricularNode4.9506.570Details
BioGPS Gene Atlas220630_s_atBDCA4+_DentriticCells6.0506.570Details
BioGPS Gene Atlas220630_s_atBonemarrow6.6506.570Details
BioGPS Gene Atlas220630_s_atBronchialEpithelialCells6.2506.570Details
BioGPS Gene Atlas220630_s_atCD105+_Endothelial6.4506.570Details
BioGPS Gene Atlas220630_s_atCD14+_Monocytes6.6506.570Details
BioGPS Gene Atlas220630_s_atCD19+_BCells(neg._sel.)6.4006.570Details
BioGPS Gene Atlas220630_s_atCD33+_Myeloid8.0506.570Details
BioGPS Gene Atlas220630_s_atCD34+7.2006.570Details
BioGPS Gene Atlas220630_s_atCD4+_Tcells6.7506.570Details
BioGPS Gene Atlas220630_s_atCD56+_NKCells7.1006.570Details
BioGPS Gene Atlas220630_s_atCD71+_EarlyErythroid5.9506.570Details
BioGPS Gene Atlas220630_s_atCD8+_Tcells6.0506.570Details
BioGPS Gene Atlas220630_s_atCardiacMyocytes7.9006.570Details
BioGPS Gene Atlas220630_s_atCaudatenucleus5.7506.570Details
BioGPS Gene Atlas220630_s_atCerebellum5.5506.570Details
BioGPS Gene Atlas220630_s_atCerebellumPeduncles7.4006.570Details
BioGPS Gene Atlas220630_s_atCiliaryGanglion4.5506.570Details
BioGPS Gene Atlas220630_s_atCingulateCortex6.5506.570Details
BioGPS Gene Atlas220630_s_atColorectaladenocarcinoma6.5006.570Details
BioGPS Gene Atlas220630_s_atDorsalRootGanglion5.0506.570Details
BioGPS Gene Atlas220630_s_atFetalThyroid6.2506.570Details
BioGPS Gene Atlas220630_s_atFetalbrain6.3006.570Details
BioGPS Gene Atlas220630_s_atFetalliver5.5506.570Details
BioGPS Gene Atlas220630_s_atFetallung5.5006.570Details
BioGPS Gene Atlas220630_s_atGlobusPallidus4.6506.570Details
BioGPS Gene Atlas220630_s_atHeart8.2506.570Details
BioGPS Gene Atlas220630_s_atHypothalamus6.9006.570Details
BioGPS Gene Atlas220630_s_atKidney5.3006.570Details
BioGPS Gene Atlas220630_s_atLeukemia_chronicMyelogenousK-5625.8506.570Details
BioGPS Gene Atlas220630_s_atLeukemia_promyelocytic-HL-605.6506.570Details
BioGPS Gene Atlas220630_s_atLeukemialymphoblastic(MOLT-4)5.2506.570Details
BioGPS Gene Atlas220630_s_atLiver8.7506.570Details
BioGPS Gene Atlas220630_s_atLung13.2006.570Details
BioGPS Gene Atlas220630_s_atLymphnode5.5506.570Details
BioGPS Gene Atlas220630_s_atLymphoma_burkitts(Daudi)8.2006.570Details
BioGPS Gene Atlas220630_s_atLymphoma_burkitts(Raji)9.7006.570Details
BioGPS Gene Atlas220630_s_atMedullaOblongata5.9006.570Details
BioGPS Gene Atlas220630_s_atOccipitalLobe5.8006.570Details
BioGPS Gene Atlas220630_s_atOlfactoryBulb5.1006.570Details
BioGPS Gene Atlas220630_s_atOvary4.3006.570Details
BioGPS Gene Atlas220630_s_atPancreas5.2006.570Details
BioGPS Gene Atlas220630_s_atPancreaticIslet6.8506.570Details
BioGPS Gene Atlas220630_s_atParietalLobe6.9006.570Details
BioGPS Gene Atlas220630_s_atPituitary7.5506.570Details
BioGPS Gene Atlas220630_s_atPlacenta6.4006.570Details
BioGPS Gene Atlas220630_s_atPons8.1506.570Details
BioGPS Gene Atlas220630_s_atPrefrontalCortex7.8006.570Details
BioGPS Gene Atlas220630_s_atProstate7.6006.570Details
BioGPS Gene Atlas220630_s_atSalivarygland5.2506.570Details
BioGPS Gene Atlas220630_s_atSkeletalMuscle8.7006.570Details
BioGPS Gene Atlas220630_s_atSkin5.2006.570Details
BioGPS Gene Atlas220630_s_atSmoothMuscle6.9506.570Details
BioGPS Gene Atlas220630_s_atSpinalcord6.9506.570Details
BioGPS Gene Atlas220630_s_atSubthalamicNucleus5.7506.570Details
BioGPS Gene Atlas220630_s_atSuperiorCervicalGanglion8.5006.570Details
BioGPS Gene Atlas220630_s_atTemporalLobe6.0006.570Details
BioGPS Gene Atlas220630_s_atTestis5.5506.570Details
BioGPS Gene Atlas220630_s_atTestisGermCell5.4506.570Details
BioGPS Gene Atlas220630_s_atTestisIntersitial5.4506.570Details
BioGPS Gene Atlas220630_s_atTestisLeydigCell6.4006.570Details
BioGPS Gene Atlas220630_s_atTestisSeminiferousTubule5.5506.570Details
BioGPS Gene Atlas220630_s_atThalamus6.5506.570Details
BioGPS Gene Atlas220630_s_atThymus5.1506.570Details
BioGPS Gene Atlas220630_s_atThyroid8.1006.570Details
BioGPS Gene Atlas220630_s_atTongue6.5506.570Details
BioGPS Gene Atlas220630_s_atTonsil6.3006.570Details
BioGPS Gene Atlas220630_s_atTrachea5.4006.570Details
BioGPS Gene Atlas220630_s_atTrigeminalGanglion7.0506.570Details
BioGPS Gene Atlas220630_s_atUterus5.3006.570Details
BioGPS Gene Atlas220630_s_atUterusCorpus6.1006.570Details
BioGPS Gene Atlas220630_s_atWholeBlood7.1506.570Details
BioGPS Gene Atlas220630_s_atWholebrain5.3006.570Details
BioGPS Gene Atlas220630_s_atcolon6.5006.570Details
BioGPS Gene Atlas220630_s_atpineal_day7.4606.570Details
BioGPS Gene Atlas220630_s_atpineal_night7.4206.570Details
BioGPS Gene Atlas220630_s_atretina7.8006.570Details
BioGPS Gene Atlas220630_s_atsmall_intestine6.5006.570Details
BioGPS NCI60220630_s_at7864.1544.210Details
BioGPS NCI60220630_s_atA1724.0264.210Details
BioGPS NCI60220630_s_atA2044.0524.210Details
BioGPS NCI60220630_s_atA3614.1484.210Details
BioGPS NCI60220630_s_atA4984.0994.210Details
BioGPS NCI60220630_s_atA5494.1394.210Details
BioGPS NCI60220630_s_atACC34.1804.210Details
BioGPS NCI60220630_s_atACHN3.7184.210Details
BioGPS NCI60220630_s_atALVA314.3774.210Details
BioGPS NCI60220630_s_atCAKI14.1954.210Details
BioGPS NCI60220630_s_atCCRT CEM4.5964.210Details
BioGPS NCI60220630_s_atCOLO2054.1134.210Details
BioGPS NCI60220630_s_atDLD14.0554.210Details
BioGPS NCI60220630_s_atDU1454.5774.210Details
BioGPS NCI60220630_s_atEKVX3.9494.210Details
BioGPS NCI60220630_s_atGM1334.1874.210Details
BioGPS NCI60220630_s_atGM16004.2834.210Details
BioGPS NCI60220630_s_atGM23134.1554.210Details
BioGPS NCI60220630_s_atGM23454.0604.210Details
BioGPS NCI60220630_s_atGM24934.2294.210Details
BioGPS NCI60220630_s_atGM974.2254.210Details
BioGPS NCI60220630_s_atHCC29983.9074.210Details
BioGPS NCI60220630_s_atHCT1164.0754.210Details
BioGPS NCI60220630_s_atHCT153.8084.210Details
BioGPS NCI60220630_s_atHEK 293 T-rex8.1074.210Details
BioGPS NCI60220630_s_atHEK 293T4.1334.210Details
BioGPS NCI60220630_s_atHEK2934.1174.210Details
BioGPS NCI60220630_s_atHELA3.8164.210Details
BioGPS NCI60220630_s_atHEPG24.0824.210Details
BioGPS NCI60220630_s_atHL604.3124.210Details
BioGPS NCI60220630_s_atHOP624.0584.210Details
BioGPS NCI60220630_s_atHOP923.8554.210Details
BioGPS NCI60220630_s_atHS578T4.0924.210Details
BioGPS NCI60220630_s_atHSG4.0324.210Details
BioGPS NCI60220630_s_atHT10804.0634.210Details
BioGPS NCI60220630_s_atHT294.6424.210Details
BioGPS NCI60220630_s_atIGROV14.0724.210Details
BioGPS NCI60220630_s_atIOSE804.0654.210Details
BioGPS NCI60220630_s_atJURKAT4.1004.210Details
BioGPS NCI60220630_s_atK5624.4024.210Details
BioGPS NCI60220630_s_atKM124.1534.210Details
BioGPS NCI60220630_s_atLN184.0324.210Details
BioGPS NCI60220630_s_atLNCAP4.1094.210Details
BioGPS NCI60220630_s_atLOX IMVI4.1044.210Details
BioGPS NCI60220630_s_atM143.9084.210Details
BioGPS NCI60220630_s_atMALME 3M4.3644.210Details
BioGPS NCI60220630_s_atMCF73.9574.210Details
BioGPS NCI60220630_s_atMD MB2314.1454.210Details
BioGPS NCI60220630_s_atMDA MB4354.2244.210Details
BioGPS NCI60220630_s_atMOLT44.1634.210Details
BioGPS NCI60220630_s_atNCI 4604.1834.210Details
BioGPS NCI60220630_s_atNCI H2264.1624.210Details
BioGPS NCI60220630_s_atNCI H234.1204.210Details
BioGPS NCI60220630_s_atNCI H322M4.0964.210Details
BioGPS NCI60220630_s_atNCVADR RES3.8614.210Details
BioGPS NCI60220630_s_atOVCAR34.2124.210Details
BioGPS NCI60220630_s_atOVCAR44.0744.210Details
BioGPS NCI60220630_s_atOVCAR54.0684.210Details
BioGPS NCI60220630_s_atOVCAR83.8564.210Details
BioGPS NCI60220630_s_atPANC14.0914.210Details
BioGPS NCI60220630_s_atRL74.1264.210Details
BioGPS NCI60220630_s_atRPMI 82264.1124.210Details
BioGPS NCI60220630_s_atRS118464.2234.210Details
BioGPS NCI60220630_s_atRXF3934.0734.210Details
BioGPS NCI60220630_s_atSAOS24.1154.210Details
BioGPS NCI60220630_s_atSF2684.0694.210Details
BioGPS NCI60220630_s_atSF2954.0334.210Details
BioGPS NCI60220630_s_atSF5393.9994.210Details
BioGPS NCI60220630_s_atSHSYSY+RA4.0304.210Details
BioGPS NCI60220630_s_atSHSYSY-RA4.0774.210Details
BioGPS NCI60220630_s_atSKMEL24.1024.210Details
BioGPS NCI60220630_s_atSKMEL284.0894.210Details
BioGPS NCI60220630_s_atSKMEL54.5024.210Details
BioGPS NCI60220630_s_atSKOV34.1364.210Details
BioGPS NCI60220630_s_atSN12C4.1034.210Details
BioGPS NCI60220630_s_atSNB193.9014.210Details
BioGPS NCI60220630_s_atSNB754.0794.210Details
BioGPS NCI60220630_s_atSR4.1154.210Details
BioGPS NCI60220630_s_atSW6204.1594.210Details
BioGPS NCI60220630_s_atT244.1304.210Details
BioGPS NCI60220630_s_atT3M44.2944.210Details
BioGPS NCI60220630_s_atTK104.0874.210Details
BioGPS NCI60220630_s_atU1184.0824.210Details
BioGPS NCI60220630_s_atU1384.0214.210Details
BioGPS NCI60220630_s_atU20S4.1224.210Details
BioGPS NCI60220630_s_atU2514.0784.210Details
BioGPS NCI60220630_s_atU874.0084.210Details
BioGPS NCI60220630_s_atUACC2574.0674.210Details
BioGPS NCI60220630_s_atUACC624.1564.210Details
BioGPS NCI60220630_s_atUO313.8954.210Details
BioGPS NCI60220630_s_atZR75_14.2234.210Details
BioGPS NCI60220630_s_atastrocytes4.1674.210Details
BioGPS NCI60220630_s_athuh-75.1204.210Details