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Gene ID: 1103 | CHAT Antibody Resource


CHAT Antibody Resource
Gene Full Name: 
choline O-acetyltransferase
Uniprot: 
P28329
Protein Name: 
choline O-acetyltransferase
Nucleotide: 
NM_020984
Alias: 
CMS1A;CMS1A2;CHOACTASE;
Ensembl: 
ENSG00000070748
Location: 
10q11.2
HPRD: 
07510
NCBI Gene: 
1103
MIM: 
118490

Summary: 
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]
Function: 
Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
Subcellular location: 
PTM: 
Disease: 
Myasthenic syndrome, congenital, associated with episodic apnea (CMSEA) [MIM:254210]: An autosomal recessive congenital myasthenic syndrome. Patients have myasthenic symptoms since birth or early infancy, negative tests for anti-AChR antibodies, and abrupt episodic crises with increased weakness, bulbar paralysis, and apnea precipitated by undue exertion, fever, or excitement. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody AVARP13010_P050 CHAT Antibody - middle region (AVARP13010_P050) Polyclonal Human, Pig WB 50ug $289 Details
Monoclonal Antibody OASA04138 Chat Antibody (OASA04138) Rat IHC-AFF 0.1ml $530 Details
Polyclonal Antibody OASA06108 CHAT Antibody (OASA06108) Human IHC-AFF, WB 50ul $985 Details
Polyclonal Antibody OASA06525 Chat antibody - C-terminal region (OASA06525) Mouse ELISA, WB 0.1mg $530 Details
Polyclonal Antibody OASA07621 CHAT Antibody (OASA07621) Human ELISA 1ml $365 Details
Protein OPSA10746 RAT CHOLINE ACETYLTRANSFERASE Recombinant Protein (10ug) Rat 10ug $410 Details
Polyclonal Antibody OAEB01810 CHAT Antibody (OAEB01810) Bovine, Dog, Human WB 0.1mg $289 Details
Polyclonal Antibody OAEB01820 Chat Antibody (OAEB01820) Mouse WB 0.1mg $289 Details
Polyclonal Antibody OAAB06188 CHAT antibody - N-terminal region (OAAB06188) Human; Mouse WB, ELISA 400ul $289 Details
Polyclonal Antibody ARP30665_P050 CHAT antibody - C-terminal region (ARP30665_P050) Dog, Human WB 50ug $289 Details
Polyclonal Antibody OAPC00091 Anti-Choline Acetyltransferase (OAPC00091) Rat; Mouse; Human; Chicken; Non-human primate; Guinea Pig WB, IHC 100 ul $289 Details
Polyclonal Antibody OAPC00090 Anti-Choline Acetyltransferase (OAPC00090) Rat; Mouse; Human; Chicken; Non-human primate; Guinea Pig WB, IHC 100 ul $329 Details

Show all CHAT antibodies


Product Images
CHAT antibody - C-terminal region (ARP30665_P050) in Human Fetal Brain cells using Western Blot

Sample Type: Human Fetal Brain

CHAT antibody - N-terminal region (OAAB06188) in Mouse Liver cells using Western Blot

Sample Type: Mouse Liver

CHAT antibody - N-terminal region (OAAB06188) in NCI-H460 cells using Western Blot

Sample Type: NCI-H460

CHAT Antibody (OAEB01810) in Human Placenta cells using Western Blot

Sample Type: Human Placenta

Chat Antibody (OAEB01820) in Mouse Brain cells using Western Blot

Sample Type: Mouse Brain


CHAT Protocols

Publications

Related Gene Trend Categories

Species
Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas221197_s_at721_B_lymphoblasts6.2505.300Details
BioGPS Gene Atlas221197_s_atAdipocyte5.1505.300Details
BioGPS Gene Atlas221197_s_atAdrenalCortex5.4005.300Details
BioGPS Gene Atlas221197_s_atAdrenalgland4.3505.300Details
BioGPS Gene Atlas221197_s_atAmygdala5.4505.300Details
BioGPS Gene Atlas221197_s_atAppendix5.4005.300Details
BioGPS Gene Atlas221197_s_atAtrioventricularNode4.0505.300Details
BioGPS Gene Atlas221197_s_atBDCA4+_DentriticCells5.4505.300Details
BioGPS Gene Atlas221197_s_atBonemarrow5.1005.300Details
BioGPS Gene Atlas221197_s_atBronchialEpithelialCells5.1505.300Details
BioGPS Gene Atlas221197_s_atCD105+_Endothelial5.3005.300Details
BioGPS Gene Atlas221197_s_atCD14+_Monocytes5.4505.300Details
BioGPS Gene Atlas221197_s_atCD19+_BCells(neg._sel.)5.6005.300Details
BioGPS Gene Atlas221197_s_atCD33+_Myeloid6.3505.300Details
BioGPS Gene Atlas221197_s_atCD34+6.3505.300Details
BioGPS Gene Atlas221197_s_atCD4+_Tcells5.4505.300Details
BioGPS Gene Atlas221197_s_atCD56+_NKCells6.2505.300Details
BioGPS Gene Atlas221197_s_atCD71+_EarlyErythroid4.8505.300Details
BioGPS Gene Atlas221197_s_atCD8+_Tcells4.9505.300Details
BioGPS Gene Atlas221197_s_atCardiacMyocytes6.6005.300Details
BioGPS Gene Atlas221197_s_atCaudatenucleus4.6505.300Details
BioGPS Gene Atlas221197_s_atCerebellum4.2005.300Details
BioGPS Gene Atlas221197_s_atCerebellumPeduncles5.8505.300Details
BioGPS Gene Atlas221197_s_atCiliaryGanglion3.6505.300Details
BioGPS Gene Atlas221197_s_atCingulateCortex5.3505.300Details
BioGPS Gene Atlas221197_s_atColorectaladenocarcinoma5.2005.300Details
BioGPS Gene Atlas221197_s_atDorsalRootGanglion4.2505.300Details
BioGPS Gene Atlas221197_s_atFetalThyroid5.1005.300Details
BioGPS Gene Atlas221197_s_atFetalbrain5.2505.300Details
BioGPS Gene Atlas221197_s_atFetalliver4.5005.300Details
BioGPS Gene Atlas221197_s_atFetallung4.7005.300Details
BioGPS Gene Atlas221197_s_atGlobusPallidus3.8005.300Details
BioGPS Gene Atlas221197_s_atHeart6.8505.300Details
BioGPS Gene Atlas221197_s_atHypothalamus5.6505.300Details
BioGPS Gene Atlas221197_s_atKidney4.1505.300Details
BioGPS Gene Atlas221197_s_atLeukemia_chronicMyelogenousK-5624.7005.300Details
BioGPS Gene Atlas221197_s_atLeukemia_promyelocytic-HL-604.6005.300Details
BioGPS Gene Atlas221197_s_atLeukemialymphoblastic(MOLT-4)4.2505.300Details
BioGPS Gene Atlas221197_s_atLiver8.4505.300Details
BioGPS Gene Atlas221197_s_atLung5.8005.300Details
BioGPS Gene Atlas221197_s_atLymphnode4.5005.300Details
BioGPS Gene Atlas221197_s_atLymphoma_burkitts(Daudi)6.6505.300Details
BioGPS Gene Atlas221197_s_atLymphoma_burkitts(Raji)7.3005.300Details
BioGPS Gene Atlas221197_s_atMedullaOblongata4.7505.300Details
BioGPS Gene Atlas221197_s_atOccipitalLobe4.7005.300Details
BioGPS Gene Atlas221197_s_atOlfactoryBulb4.1005.300Details
BioGPS Gene Atlas221197_s_atOvary3.6005.300Details
BioGPS Gene Atlas221197_s_atPancreas4.2505.300Details
BioGPS Gene Atlas221197_s_atPancreaticIslet5.6005.300Details
BioGPS Gene Atlas221197_s_atParietalLobe5.5005.300Details
BioGPS Gene Atlas221197_s_atPituitary6.4505.300Details
BioGPS Gene Atlas221197_s_atPlacenta5.4005.300Details
BioGPS Gene Atlas221197_s_atPons4.9505.300Details
BioGPS Gene Atlas221197_s_atPrefrontalCortex6.2505.300Details
BioGPS Gene Atlas221197_s_atProstate6.6005.300Details
BioGPS Gene Atlas221197_s_atSalivarygland4.1505.300Details
BioGPS Gene Atlas221197_s_atSkeletalMuscle6.0505.300Details
BioGPS Gene Atlas221197_s_atSkin3.9505.300Details
BioGPS Gene Atlas221197_s_atSmoothMuscle5.9505.300Details
BioGPS Gene Atlas221197_s_atSpinalcord5.5005.300Details
BioGPS Gene Atlas221197_s_atSubthalamicNucleus4.7005.300Details
BioGPS Gene Atlas221197_s_atSuperiorCervicalGanglion6.3005.300Details
BioGPS Gene Atlas221197_s_atTemporalLobe4.7005.300Details
BioGPS Gene Atlas221197_s_atTestis4.5005.300Details
BioGPS Gene Atlas221197_s_atTestisGermCell4.3505.300Details
BioGPS Gene Atlas221197_s_atTestisIntersitial4.4505.300Details
BioGPS Gene Atlas221197_s_atTestisLeydigCell5.1505.300Details
BioGPS Gene Atlas221197_s_atTestisSeminiferousTubule4.4505.300Details
BioGPS Gene Atlas221197_s_atThalamus5.2505.300Details
BioGPS Gene Atlas221197_s_atThymus4.2005.300Details
BioGPS Gene Atlas221197_s_atThyroid6.5505.300Details
BioGPS Gene Atlas221197_s_atTongue5.1005.300Details
BioGPS Gene Atlas221197_s_atTonsil5.1005.300Details
BioGPS Gene Atlas221197_s_atTrachea4.3505.300Details
BioGPS Gene Atlas221197_s_atTrigeminalGanglion5.5505.300Details
BioGPS Gene Atlas221197_s_atUterus4.6005.300Details
BioGPS Gene Atlas221197_s_atUterusCorpus6.3005.300Details
BioGPS Gene Atlas221197_s_atWholeBlood5.7505.300Details
BioGPS Gene Atlas221197_s_atWholebrain4.4005.300Details
BioGPS Gene Atlas221197_s_atcolon5.1505.300Details
BioGPS Gene Atlas221197_s_atpineal_day6.4405.300Details
BioGPS Gene Atlas221197_s_atpineal_night6.2605.300Details
BioGPS Gene Atlas221197_s_atretina6.2755.300Details
BioGPS Gene Atlas221197_s_atsmall_intestine5.0505.300Details
BioGPS NCI60221197_s_at7865.2345.170Details
BioGPS NCI60221197_s_atA1725.0065.170Details
BioGPS NCI60221197_s_atA2045.1095.170Details
BioGPS NCI60221197_s_atA3615.2465.170Details
BioGPS NCI60221197_s_atA4985.1285.170Details
BioGPS NCI60221197_s_atA5495.2055.170Details
BioGPS NCI60221197_s_atACC35.3205.170Details
BioGPS NCI60221197_s_atACHN4.7455.170Details
BioGPS NCI60221197_s_atALVA315.3545.170Details
BioGPS NCI60221197_s_atCAKI15.2825.170Details
BioGPS NCI60221197_s_atCCRT CEM5.5335.170Details
BioGPS NCI60221197_s_atCOLO2055.1465.170Details
BioGPS NCI60221197_s_atDLD15.1005.170Details
BioGPS NCI60221197_s_atDU1454.8605.170Details
BioGPS NCI60221197_s_atEKVX4.8915.170Details
BioGPS NCI60221197_s_atGM1335.4065.170Details
BioGPS NCI60221197_s_atGM16005.7255.170Details
BioGPS NCI60221197_s_atGM23135.4175.170Details
BioGPS NCI60221197_s_atGM23455.1785.170Details
BioGPS NCI60221197_s_atGM24935.3525.170Details
BioGPS NCI60221197_s_atGM976.1805.170Details
BioGPS NCI60221197_s_atHCC29984.6205.170Details
BioGPS NCI60221197_s_atHCT1165.1385.170Details
BioGPS NCI60221197_s_atHCT154.9585.170Details
BioGPS NCI60221197_s_atHEK 293 T-rex5.4655.170Details
BioGPS NCI60221197_s_atHEK 293T5.1865.170Details
BioGPS NCI60221197_s_atHEK2935.1515.170Details
BioGPS NCI60221197_s_atHELA4.9295.170Details
BioGPS NCI60221197_s_atHEPG25.1745.170Details
BioGPS NCI60221197_s_atHL605.3985.170Details
BioGPS NCI60221197_s_atHOP625.1655.170Details
BioGPS NCI60221197_s_atHOP925.0735.170Details
BioGPS NCI60221197_s_atHS578T5.1075.170Details
BioGPS NCI60221197_s_atHSG5.0535.170Details
BioGPS NCI60221197_s_atHT10805.0355.170Details
BioGPS NCI60221197_s_atHT295.7065.170Details
BioGPS NCI60221197_s_atIGROV15.1115.170Details
BioGPS NCI60221197_s_atIOSE805.1175.170Details
BioGPS NCI60221197_s_atJURKAT5.1475.170Details
BioGPS NCI60221197_s_atK5625.4045.170Details
BioGPS NCI60221197_s_atKM125.3045.170Details
BioGPS NCI60221197_s_atLN184.9655.170Details
BioGPS NCI60221197_s_atLNCAP5.1605.170Details
BioGPS NCI60221197_s_atLOX IMVI5.1375.170Details
BioGPS NCI60221197_s_atM145.1015.170Details
BioGPS NCI60221197_s_atMALME 3M5.3755.170Details
BioGPS NCI60221197_s_atMCF74.9875.170Details
BioGPS NCI60221197_s_atMD MB2315.1745.170Details
BioGPS NCI60221197_s_atMDA MB4355.4055.170Details
BioGPS NCI60221197_s_atMOLT45.4975.170Details
BioGPS NCI60221197_s_atNCI 4605.2555.170Details
BioGPS NCI60221197_s_atNCI H2265.2345.170Details
BioGPS NCI60221197_s_atNCI H235.1015.170Details
BioGPS NCI60221197_s_atNCI H322M5.1705.170Details
BioGPS NCI60221197_s_atNCVADR RES4.7365.170Details
BioGPS NCI60221197_s_atOVCAR35.3255.170Details
BioGPS NCI60221197_s_atOVCAR45.1355.170Details
BioGPS NCI60221197_s_atOVCAR55.0965.170Details
BioGPS NCI60221197_s_atOVCAR84.7155.170Details
BioGPS NCI60221197_s_atPANC15.2175.170Details
BioGPS NCI60221197_s_atRL75.2485.170Details
BioGPS NCI60221197_s_atRPMI 82265.3305.170Details
BioGPS NCI60221197_s_atRS118465.3275.170Details
BioGPS NCI60221197_s_atRXF3935.1115.170Details
BioGPS NCI60221197_s_atSAOS25.2215.170Details
BioGPS NCI60221197_s_atSF2685.1425.170Details
BioGPS NCI60221197_s_atSF2955.0985.170Details
BioGPS NCI60221197_s_atSF5394.7255.170Details
BioGPS NCI60221197_s_atSHSYSY+RA5.0505.170Details
BioGPS NCI60221197_s_atSHSYSY-RA5.0275.170Details
BioGPS NCI60221197_s_atSKMEL25.1465.170Details
BioGPS NCI60221197_s_atSKMEL285.1625.170Details
BioGPS NCI60221197_s_atSKMEL55.0455.170Details
BioGPS NCI60221197_s_atSKOV35.2675.170Details
BioGPS NCI60221197_s_atSN12C5.0965.170Details
BioGPS NCI60221197_s_atSNB194.7455.170Details
BioGPS NCI60221197_s_atSNB755.1335.170Details
BioGPS NCI60221197_s_atSR5.2135.170Details
BioGPS NCI60221197_s_atSW6205.1435.170Details
BioGPS NCI60221197_s_atT245.2565.170Details
BioGPS NCI60221197_s_atT3M45.3085.170Details
BioGPS NCI60221197_s_atTK105.1155.170Details
BioGPS NCI60221197_s_atU1185.0775.170Details
BioGPS NCI60221197_s_atU1384.9865.170Details
BioGPS NCI60221197_s_atU20S5.0795.170Details
BioGPS NCI60221197_s_atU2515.1055.170Details
BioGPS NCI60221197_s_atU875.0755.170Details
BioGPS NCI60221197_s_atUACC2575.0885.170Details
BioGPS NCI60221197_s_atUACC625.1975.170Details
BioGPS NCI60221197_s_atUO314.9285.170Details
BioGPS NCI60221197_s_atZR75_15.2605.170Details
BioGPS NCI60221197_s_atastrocytes5.2295.170Details
BioGPS NCI60221197_s_athuh-75.4305.170Details