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Gene ID: 9023 | CH25H Antibody Resource


CH25H Antibody Resource
Gene Full Name: 
cholesterol 25-hydroxylase
Uniprot: 
O95992
Protein Name: 
cholesterol 25-hydroxylase
Nucleotide: 
NM_003956
Alias: 
C25H;
Ensembl: 
ENSG00000138135
Location: 
10q23
HPRD: 
05183
NCBI Gene: 
9023
MIM: 
604551

Summary: 
This is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates. [provided by RefSeq, Jul 2008]
Function: 
Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
Subcellular location: 
Endoplasmic reticulum membrane; Multi-pass membrane protein.
PTM: 
Glycoprotein;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP65536_P050 CH25H Antibody - C-terminal region (ARP65536_P050) Human WB 50ug $289 Details
Polyclonal Antibody ARP65535_P050 CH25H Antibody (ARP65535_P050) Polyclonal Bovine, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish Not tested 50 ug $125 Details

Show all CH25H antibodies


Product Images
CH25H Antibody - C-terminal region (ARP65536_P050) in Human Fetal Brain cells using Western Blot

Sample Type: Human Fetal Brain


CH25H Protocols
Publications

Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP65536 Bovine CH25H antibody; Bos taurus CH25H antibody Q0P599 93.0%
ARP65535 Bovine CH25H antibody; Bos taurus CH25H antibody Q0P599 92.0%
ARP65536 Cat CH25H antibody; Felis catus CH25H antibody M3XEB6 93.0%
ARP65535 Cat CH25H antibody; Felis catus CH25H antibody M3XEB6 86.0%
ARP65535 Chimpanzee CH25H antibody; Pan troglodytes CH25H antibody K7CMM7 100.0%
ARP65536 Chimpanzee CH25H antibody; Pan troglodytes CH25H antibody K7CMM7 100.0%
ARP65535 Chimpanzee CH25H antibody; Pan troglodytes CH25H antibody H2Q286 100.0%
ARP65536 Chimpanzee CH25H antibody; Pan troglodytes CH25H antibody H2Q286 100.0%
ARP65535 Chinese softshell turtle CH25H antibody; Pelodiscus sinensis CH25H antibody K7EY27 89.0%
ARP65536 Chinese softshell turtle CH25H antibody; Pelodiscus sinensis CH25H antibody K7EY27 86.0%
ARP65535 Domestic duck CH25H antibody; Anas platyrhynchos CH25H antibody U3I2X5 89.0%
ARP65536 Domestic duck CH25H antibody; Anas platyrhynchos CH25H antibody U3I2X5 86.0%
ARP65536 Duckbill platypus CH25H antibody; Ornithorhynchus anatinus CH25H antibody F6RV21 93.0%
ARP65536 European domestic ferret CH25H antibody; Mustela putorius furo CH25H antibody M3Z8B5 93.0%
ARP65535 European domestic ferret CH25H antibody; Mustela putorius furo CH25H antibody M3Z8B5 79.0%
ARP65536 Giant panda CH25H antibody; Ailuropoda melanoleuca CH25H antibody G1MP52 93.0%
ARP65535 Giant panda CH25H antibody; Ailuropoda melanoleuca CH25H antibody G1MP52 79.0%
ARP65535 Horse CH25H antibody; Equus caballus CH25H antibody F6T000 93.0%
ARP65536 Horse CH25H antibody; Equus caballus CH25H antibody F6T000 93.0%
ARP65535 Human CH25H antibody; Homo sapiens CH25H antibody O95992 100.0%
ARP65536 Human CH25H antibody; Homo sapiens CH25H antibody O95992 100.0%
ARP65535 Mouse CH25H antibody; Mus musculus CH25H antibody Q9Z0F5 100.0%
ARP65536 Mouse CH25H antibody; Mus musculus CH25H antibody Q9Z0F5 93.0%
ARP65535 Pig CH25H antibody; Sus scrofa CH25H antibody F1SCY5 93.0%
ARP65536 Pig CH25H antibody; Sus scrofa CH25H antibody F1SCY5 93.0%
ARP65535 Pig CH25H antibody; Sus scrofa CH25H antibody Q4G1G8 93.0%
ARP65536 Pig CH25H antibody; Sus scrofa CH25H antibody Q4G1G8 92.0%
ARP65536 Rabbit CH25H antibody; Oryctolagus cuniculus CH25H antibody G1SDI5 93.0%
ARP65535 Rabbit CH25H antibody; Oryctolagus cuniculus CH25H antibody G1SDI5 92.0%
ARP65535 Rat CH25H antibody; Rattus norvegicus CH25H antibody Q4QQV7 100.0%
ARP65536 Rat CH25H antibody; Rattus norvegicus CH25H antibody Q4QQV7 93.0%
ARP65536 Rhesus macaque CH25H antibody; Macaca mulatta CH25H antibody F7EC50 100.0%
ARP65535 Rhesus macaque CH25H antibody; Macaca mulatta CH25H antibody F7EC50 93.0%
ARP65535 Small-eared galago CH25H antibody; Otolemur garnettii CH25H antibody H0Y1S6 93.0%
ARP65536 Small-eared galago CH25H antibody; Otolemur garnettii CH25H antibody H0Y1S6 93.0%
ARP65536 Southern platyfish CH25H antibody; Xiphophorus maculatus CH25H antibody M3ZQZ1 82.0%
ARP65536 Spotted green pufferfish CH25H antibody; Tetraodon nigroviridis CH25H antibody H3D1I8 82.0%
ARP65535 Sumatran orangutan CH25H antibody; Pongo abelii CH25H antibody H2NAY1 100.0%
ARP65536 Sumatran orangutan CH25H antibody; Pongo abelii CH25H antibody H2NAY1 100.0%
ARP65536 Tasmanian devil CH25H antibody; Sarcophilus harrisii CH25H antibody G3VJ95 86.0%
ARP65535 Tasmanian devil CH25H antibody; Sarcophilus harrisii CH25H antibody G3VJ95 82.0%
ARP65535 Thirteen-lined ground squirrel CH25H antibody; Spermophilus tridecemlineatus CH25H antibody I3MKC7 100.0%
ARP65536 Thirteen-lined ground squirrel CH25H antibody; Spermophilus tridecemlineatus CH25H antibody I3MKC7 93.0%
ARP65536 White-tufted-ear marmoset CH25H antibody; Callithrix jacchus CH25H antibody F7HPR9 100.0%
ARP65535 White-tufted-ear marmoset CH25H antibody; Callithrix jacchus CH25H antibody F7HPR9 86.0%
ARP65535 Zebra finch CH25H antibody; Taeniopygia guttata CH25H antibody H0ZDA2 89.0%
ARP65536 Zebra finch CH25H antibody; Taeniopygia guttata CH25H antibody H0ZDA2 86.0%
ARP65535 Zebrafish CH25H antibody; Danio rerio CH25H antibody Q5PRC0 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas206932_at721_B_lymphoblasts5.9006.160Details
BioGPS Gene Atlas206932_atAdipocyte5.0006.160Details
BioGPS Gene Atlas206932_atAdrenalCortex5.6506.160Details
BioGPS Gene Atlas206932_atAdrenalgland4.4506.160Details
BioGPS Gene Atlas206932_atAmygdala5.8506.160Details
BioGPS Gene Atlas206932_atAppendix6.2006.160Details
BioGPS Gene Atlas206932_atAtrioventricularNode4.4006.160Details
BioGPS Gene Atlas206932_atBDCA4+_DentriticCells5.2006.160Details
BioGPS Gene Atlas206932_atBonemarrow5.0006.160Details
BioGPS Gene Atlas206932_atBronchialEpithelialCells4.9006.160Details
BioGPS Gene Atlas206932_atCD105+_Endothelial5.0506.160Details
BioGPS Gene Atlas206932_atCD14+_Monocytes5.4006.160Details
BioGPS Gene Atlas206932_atCD19+_BCells(neg._sel.)5.3506.160Details
BioGPS Gene Atlas206932_atCD33+_Myeloid6.3506.160Details
BioGPS Gene Atlas206932_atCD34+6.1006.160Details
BioGPS Gene Atlas206932_atCD4+_Tcells5.3006.160Details
BioGPS Gene Atlas206932_atCD56+_NKCells5.8506.160Details
BioGPS Gene Atlas206932_atCD71+_EarlyErythroid4.7506.160Details
BioGPS Gene Atlas206932_atCD8+_Tcells4.7006.160Details
BioGPS Gene Atlas206932_atCardiacMyocytes7.5506.160Details
BioGPS Gene Atlas206932_atCaudatenucleus4.5006.160Details
BioGPS Gene Atlas206932_atCerebellum4.1006.160Details
BioGPS Gene Atlas206932_atCerebellumPeduncles7.0506.160Details
BioGPS Gene Atlas206932_atCiliaryGanglion6.1006.160Details
BioGPS Gene Atlas206932_atCingulateCortex5.2006.160Details
BioGPS Gene Atlas206932_atColorectaladenocarcinoma5.0006.160Details
BioGPS Gene Atlas206932_atDorsalRootGanglion4.5506.160Details
BioGPS Gene Atlas206932_atFetalThyroid5.0006.160Details
BioGPS Gene Atlas206932_atFetalbrain4.9506.160Details
BioGPS Gene Atlas206932_atFetalliver4.3506.160Details
BioGPS Gene Atlas206932_atFetallung4.1506.160Details
BioGPS Gene Atlas206932_atGlobusPallidus4.2006.160Details
BioGPS Gene Atlas206932_atHeart9.3006.160Details
BioGPS Gene Atlas206932_atHypothalamus6.0506.160Details
BioGPS Gene Atlas206932_atKidney4.2506.160Details
BioGPS Gene Atlas206932_atLeukemia_chronicMyelogenousK-5624.6006.160Details
BioGPS Gene Atlas206932_atLeukemia_promyelocytic-HL-604.4506.160Details
BioGPS Gene Atlas206932_atLeukemialymphoblastic(MOLT-4)3.9006.160Details
BioGPS Gene Atlas206932_atLiver6.7006.160Details
BioGPS Gene Atlas206932_atLung5.6506.160Details
BioGPS Gene Atlas206932_atLymphnode4.5006.160Details
BioGPS Gene Atlas206932_atLymphoma_burkitts(Daudi)6.5006.160Details
BioGPS Gene Atlas206932_atLymphoma_burkitts(Raji)7.1006.160Details
BioGPS Gene Atlas206932_atMedullaOblongata4.6006.160Details
BioGPS Gene Atlas206932_atOccipitalLobe4.5006.160Details
BioGPS Gene Atlas206932_atOlfactoryBulb7.8506.160Details
BioGPS Gene Atlas206932_atOvary3.5006.160Details
BioGPS Gene Atlas206932_atPancreas4.1006.160Details
BioGPS Gene Atlas206932_atPancreaticIslet5.5006.160Details
BioGPS Gene Atlas206932_atParietalLobe5.4006.160Details
BioGPS Gene Atlas206932_atPituitary6.5506.160Details
BioGPS Gene Atlas206932_atPlacenta5.1006.160Details
BioGPS Gene Atlas206932_atPons4.8506.160Details
BioGPS Gene Atlas206932_atPrefrontalCortex6.1506.160Details
BioGPS Gene Atlas206932_atProstate5.9506.160Details
BioGPS Gene Atlas206932_atSalivarygland4.2506.160Details
BioGPS Gene Atlas206932_atSkeletalMuscle5.8506.160Details
BioGPS Gene Atlas206932_atSkin4.2506.160Details
BioGPS Gene Atlas206932_atSmoothMuscle6.0006.160Details
BioGPS Gene Atlas206932_atSpinalcord5.5506.160Details
BioGPS Gene Atlas206932_atSubthalamicNucleus4.7506.160Details
BioGPS Gene Atlas206932_atSuperiorCervicalGanglion5.8506.160Details
BioGPS Gene Atlas206932_atTemporalLobe4.9506.160Details
BioGPS Gene Atlas206932_atTestis4.3506.160Details
BioGPS Gene Atlas206932_atTestisGermCell4.2506.160Details
BioGPS Gene Atlas206932_atTestisIntersitial4.2506.160Details
BioGPS Gene Atlas206932_atTestisLeydigCell5.1006.160Details
BioGPS Gene Atlas206932_atTestisSeminiferousTubule4.4006.160Details
BioGPS Gene Atlas206932_atThalamus5.2006.160Details
BioGPS Gene Atlas206932_atThymus14.3006.160Details
BioGPS Gene Atlas206932_atThyroid6.1506.160Details
BioGPS Gene Atlas206932_atTongue5.1006.160Details
BioGPS Gene Atlas206932_atTonsil5.0006.160Details
BioGPS Gene Atlas206932_atTrachea17.3006.160Details
BioGPS Gene Atlas206932_atTrigeminalGanglion7.8506.160Details
BioGPS Gene Atlas206932_atUterus4.1006.160Details
BioGPS Gene Atlas206932_atUterusCorpus4.7006.160Details
BioGPS Gene Atlas206932_atWholeBlood5.4006.160Details
BioGPS Gene Atlas206932_atWholebrain4.4006.160Details
BioGPS Gene Atlas206932_atcolon5.2006.160Details
BioGPS Gene Atlas206932_atpineal_day7.1806.160Details
BioGPS Gene Atlas206932_atpineal_night6.2206.160Details
BioGPS Gene Atlas206932_atretina30.1006.160Details
BioGPS Gene Atlas206932_atsmall_intestine5.1506.160Details
BioGPS NCI60206932_at7864.41218.390Details
BioGPS NCI60206932_atA1724.05618.390Details
BioGPS NCI60206932_atA2044.28418.390Details
BioGPS NCI60206932_atA3614.35218.390Details
BioGPS NCI60206932_atA4984.30418.390Details
BioGPS NCI60206932_atA5494.38418.390Details
BioGPS NCI60206932_atACC34.46318.390Details
BioGPS NCI60206932_atACHN4.08618.390Details
BioGPS NCI60206932_atALVA314.56218.390Details
BioGPS NCI60206932_atCAKI14.57318.390Details
BioGPS NCI60206932_atCCRT CEM4.81418.390Details
BioGPS NCI60206932_atCOLO2054.31818.390Details
BioGPS NCI60206932_atDLD14.19018.390Details
BioGPS NCI60206932_atDU1454.07518.390Details
BioGPS NCI60206932_atEKVX4.07318.390Details
BioGPS NCI60206932_atGM133518.46618.390Details
BioGPS NCI60206932_atGM16004.48018.390Details
BioGPS NCI60206932_atGM2313357.44618.390Details
BioGPS NCI60206932_atGM234542.06718.390Details
BioGPS NCI60206932_atGM24934.70018.390Details
BioGPS NCI60206932_atGM974.70218.390Details
BioGPS NCI60206932_atHCC29983.98618.390Details
BioGPS NCI60206932_atHCT1164.30018.390Details
BioGPS NCI60206932_atHCT154.12918.390Details
BioGPS NCI60206932_atHEK 293 T-rex4.42518.390Details
BioGPS NCI60206932_atHEK 293T4.27418.390Details
BioGPS NCI60206932_atHEK2934.28218.390Details
BioGPS NCI60206932_atHELA3.98618.390Details
BioGPS NCI60206932_atHEPG24.30218.390Details
BioGPS NCI60206932_atHL604.41618.390Details
BioGPS NCI60206932_atHOP624.39918.390Details
BioGPS NCI60206932_atHOP924.20918.390Details
BioGPS NCI60206932_atHS578T4.25718.390Details
BioGPS NCI60206932_atHSG4.08218.390Details
BioGPS NCI60206932_atHT10804.21118.390Details
BioGPS NCI60206932_atHT294.60718.390Details
BioGPS NCI60206932_atIGROV14.22118.390Details
BioGPS NCI60206932_atIOSE804.29018.390Details
BioGPS NCI60206932_atJURKAT4.29918.390Details
BioGPS NCI60206932_atK5624.59018.390Details
BioGPS NCI60206932_atKM124.47218.390Details
BioGPS NCI60206932_atLN184.11918.390Details
BioGPS NCI60206932_atLNCAP4.31118.390Details
BioGPS NCI60206932_atLOX IMVI4.29518.390Details
BioGPS NCI60206932_atM144.27018.390Details
BioGPS NCI60206932_atMALME 3M4.71918.390Details
BioGPS NCI60206932_atMCF74.18318.390Details
BioGPS NCI60206932_atMD MB2314.34618.390Details
BioGPS NCI60206932_atMDA MB4354.81918.390Details
BioGPS NCI60206932_atMOLT44.42918.390Details
BioGPS NCI60206932_atNCI 4604.43118.390Details
BioGPS NCI60206932_atNCI H2264.40818.390Details
BioGPS NCI60206932_atNCI H234.33918.390Details
BioGPS NCI60206932_atNCI H322M4.30318.390Details
BioGPS NCI60206932_atNCVADR RES3.99718.390Details
BioGPS NCI60206932_atOVCAR34.61518.390Details
BioGPS NCI60206932_atOVCAR44.28818.390Details
BioGPS NCI60206932_atOVCAR54.24518.390Details
BioGPS NCI60206932_atOVCAR83.97418.390Details
BioGPS NCI60206932_atPANC14.36318.390Details
BioGPS NCI60206932_atRL74.38418.390Details
BioGPS NCI60206932_atRPMI 82264.43218.390Details
BioGPS NCI60206932_atRS118464.46818.390Details
BioGPS NCI60206932_atRXF3934.28018.390Details
BioGPS NCI60206932_atSAOS24.36418.390Details
BioGPS NCI60206932_atSF2684.30018.390Details
BioGPS NCI60206932_atSF2954.28218.390Details
BioGPS NCI60206932_atSF5394.11918.390Details
BioGPS NCI60206932_atSHSYSY+RA4.20318.390Details
BioGPS NCI60206932_atSHSYSY-RA4.25718.390Details
BioGPS NCI60206932_atSKMEL24.30018.390Details
BioGPS NCI60206932_atSKMEL284.32218.390Details
BioGPS NCI60206932_atSKMEL54.09718.390Details
BioGPS NCI60206932_atSKOV34.44018.390Details
BioGPS NCI60206932_atSN12C4.28118.390Details
BioGPS NCI60206932_atSNB194.13218.390Details
BioGPS NCI60206932_atSNB75374.00718.390Details
BioGPS NCI60206932_atSR4.47818.390Details
BioGPS NCI60206932_atSW6204.32518.390Details
BioGPS NCI60206932_atT244.40218.390Details
BioGPS NCI60206932_atT3M44.46118.390Details
BioGPS NCI60206932_atTK104.29918.390Details
BioGPS NCI60206932_atU11862.71818.390Details
BioGPS NCI60206932_atU1384.84818.390Details
BioGPS NCI60206932_atU20S4.20218.390Details
BioGPS NCI60206932_atU2514.29018.390Details
BioGPS NCI60206932_atU8767.88218.390Details
BioGPS NCI60206932_atUACC2574.24418.390Details
BioGPS NCI60206932_atUACC624.37918.390Details
BioGPS NCI60206932_atUO314.12318.390Details
BioGPS NCI60206932_atZR75_14.39818.390Details
BioGPS NCI60206932_atastrocytes4.33318.390Details
BioGPS NCI60206932_athuh-74.42718.390Details