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Gene ID: 84952 | CGNL1 Antibody Resource


CGNL1 Antibody Resource
Gene Full Name: 
cingulin-like 1
Uniprot: 
Q0VF96
Protein Name: 
cingulin-like protein 1
Nucleotide: 
NM_001252335
Alias: 
JACOP;
Ensembl: 
ENSG00000128849
Location: 
15q21.3
HPRD: 
09708
NCBI Gene: 
84952
MIM: 
607856

Summary: 
This gene encodes a member of the cingulin family. The encoded protein localizes to both adherens and tight cell-cell junctions and mediates junction assembly and maintenance by regulating the activity of the small GTPases RhoA and Rac1. Heterozygous chromosomal rearrangements resulting in association of the promoter for this gene with the aromatase gene are a cause of aromatase excess syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011]
Function: 
May be involved in anchoring the apical junctional complex, especially tight junctions, to actin-based cytoskeletons .
Subcellular location: 
Cell junction › tight junction. Note: Localizes to the apical junction complex composed of tight and adherens junctions .
PTM: 
Phosphoprotein;
Disease: 
Aromatase excess syndrome (AEXS) [MIM:139300]: An autosomal dominant disorder characterized by increased extraglandular aromatization of steroids that presents with heterosexual precocity in males and isosexual precocity in females. Note: The gene represented in this entry is involved in disease pathogenesis. A chromosomal aberration inv15(q21.2;q21.3) has been found in patients with aromatase excess syndrome. The inversion moves the promoter of the CGNL1 gene into a 5-prime position in relation to the aromatase coding region.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP60417_P050 CGNL1 Antibody (ARP60417_P050) Polyclonal Dog, Horse, Human Not tested 50 ug $125 Details
Polyclonal Antibody ARP60418_P050 CGNL1 Antibody (ARP60418_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB12352 CGNL1 antibody - N - terminal region (OAAB12352) Human WB 400ul $289 Details

Show all CGNL1 antibodies


Product Images
CGNL1 antibody - N - terminal region (OAAB12352) in Human, Uterus cells using Western Blot

Sample Type: Human, Uterus


CGNL1 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP60417 African elephant CGNL1 antibody; Loxodonta africana CGNL1 antibody G3TFS2 87.0%
ARP60418 African elephant CGNL1 antibody; Loxodonta africana CGNL1 antibody G3TFS2 86.0%
ARP60418 Cat CGNL1 antibody; Felis catus CGNL1 antibody M3WP88 100.0%
ARP60417 Chimpanzee CGNL1 antibody; Pan troglodytes CGNL1 antibody K7CC29 100.0%
ARP60418 Chimpanzee CGNL1 antibody; Pan troglodytes CGNL1 antibody K7CC29 100.0%
ARP60417 Chimpanzee CGNL1 antibody; Pan troglodytes CGNL1 antibody H2Q9I0 100.0%
ARP60418 Chimpanzee CGNL1 antibody; Pan troglodytes CGNL1 antibody H2Q9I0 100.0%
ARP60418 Dog CGNL1 antibody; Canis familiaris CGNL1 antibody E2QV06 100.0%
ARP60417 Dog CGNL1 antibody; Canis familiaris CGNL1 antibody E2QV06 79.0%
ARP60418 European domestic ferret CGNL1 antibody; Mustela putorius furo CGNL1 antibody M3XZ89 100.0%
ARP60417 European domestic ferret CGNL1 antibody; Mustela putorius furo CGNL1 antibody M3XZ89 79.0%
ARP60418 Giant panda CGNL1 antibody; Ailuropoda melanoleuca CGNL1 antibody G1LVP9 100.0%
ARP60417 Giant panda CGNL1 antibody; Ailuropoda melanoleuca CGNL1 antibody G1LVP9 79.0%
ARP60418 Horse CGNL1 antibody; Equus caballus CGNL1 antibody F6ZQS4 100.0%
ARP60417 Horse CGNL1 antibody; Equus caballus CGNL1 antibody F6ZQS4 86.0%
ARP60418 Human CGNL1 antibody; Homo sapiens CGNL1 antibody Q0VF96-2 100.0%
ARP60417 Human CGNL1 antibody; Homo sapiens CGNL1 antibody Q0VF96 100.0%
ARP60418 Human CGNL1 antibody; Homo sapiens CGNL1 antibody Q0VF96 100.0%
ARP60417 Human CGNL1 antibody; Homo sapiens CGNL1 antibody Q6P5Q2 100.0%
ARP60418 Mouse CGNL1 antibody; Mus musculus CGNL1 antibody B2RSU6 93.0%
ARP60418 Mouse CGNL1 antibody; Mus musculus CGNL1 antibody B2RY19 93.0%
ARP60418 Mouse CGNL1 antibody; Mus musculus CGNL1 antibody D3Z3H4 93.0%
ARP60418 Mouse CGNL1 antibody; Mus musculus CGNL1 antibody Q6AW69-3 93.0%
ARP60418 Mouse CGNL1 antibody; Mus musculus CGNL1 antibody Q6AW69-4 93.0%
ARP60418 Mouse CGNL1 antibody; Mus musculus CGNL1 antibody Q6AW69-5 93.0%
ARP60418 Mouse CGNL1 antibody; Mus musculus CGNL1 antibody Q6AW69 93.0%
ARP60417 Northern white-cheeked gibbon CGNL1 antibody; Nomascus leucogenys CGNL1 antibody G1R4T1 100.0%
ARP60418 Northern white-cheeked gibbon CGNL1 antibody; Nomascus leucogenys CGNL1 antibody G1R4T1 100.0%
ARP60418 Rabbit CGNL1 antibody; Oryctolagus cuniculus CGNL1 antibody G1SK43 79.0%
ARP60418 Rat CGNL1 antibody; Rattus norvegicus CGNL1 antibody D4A3V5 86.0%
ARP60417 Rhesus macaque CGNL1 antibody; Macaca mulatta CGNL1 antibody I2CXS9 100.0%
ARP60418 Rhesus macaque CGNL1 antibody; Macaca mulatta CGNL1 antibody I2CXS9 100.0%
ARP60417 Rhesus macaque CGNL1 antibody; Macaca mulatta CGNL1 antibody F7CYU7 100.0%
ARP60418 Rhesus macaque CGNL1 antibody; Macaca mulatta CGNL1 antibody F7CYU7 100.0%
ARP60418 Rhesus macaque CGNL1 antibody; Macaca mulatta CGNL1 antibody H9F6P7 100.0%
ARP60417 Rhesus macaque CGNL1 antibody; Macaca mulatta CGNL1 antibody H9FGC8 100.0%
ARP60417 Rhesus macaque CGNL1 antibody; Macaca mulatta CGNL1 antibody I0FII9 100.0%
ARP60418 Rhesus macaque CGNL1 antibody; Macaca mulatta CGNL1 antibody I0FII9 100.0%
ARP60417 Small-eared galago CGNL1 antibody; Otolemur garnettii CGNL1 antibody H0WNY6 100.0%
ARP60418 Small-eared galago CGNL1 antibody; Otolemur garnettii CGNL1 antibody H0WNY6 93.0%
ARP60417 Sumatran orangutan CGNL1 antibody; Pongo abelii CGNL1 antibody H2NNC1 100.0%
ARP60418 Thirteen-lined ground squirrel CGNL1 antibody; Spermophilus tridecemlineatus CGNL1 antibody I3MQH2 93.0%
ARP60417 Thirteen-lined ground squirrel CGNL1 antibody; Spermophilus tridecemlineatus CGNL1 antibody I3MQH2 79.0%

Tissue & Cell Line Gene Expression Data