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Gene ID: 5199 | CFP Antibody Resource


CFP Antibody Resource
Gene Full Name: 
complement factor properdin
Uniprot: 
P27918
Protein Name: 
properdin
Nucleotide: 
NM_002621
Alias: 
BFD;PFC;PFD;PROPERDIN;
Ensembl: 
ENSG00000126759
Location: 
Xp11.4
HPRD: 
02308
NCBI Gene: 
5199
MIM: 
300383

Summary: 
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009]
Function: 
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes.
Subcellular location: 
Secreted.
PTM: 
Disulfide bond;
Disease: 
Properdin deficiency (PFD) [MIM:312060]: Results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III). Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP56382_P050 CFP antibody - middle region (ARP56382_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Mouse, Rat WB 50ug $289 Details
Polyclonal Antibody ARP56381_P050 CFP antibody - N-terminal region (ARP56381_P050) Polyclonal Human IHC, WB 50ug $289 Details
Monoclonal Antibody OASA02780 CFP Antibody (OASA02780) Human IHC-AFF, ELISA 0.1mg $515 Details
Monoclonal Antibody OASA02781 CFP Antibody (OASA02781) Human IHC-AFF, ELISA 0.1mg $530 Details
Polyclonal Antibody OAAB06541 CFP antibody - center region (OAAB06541) Human WB, ELISA 400ul $289 Details

Show all CFP antibodies


Product Images
CFP antibody - N-terminal region (ARP56381_P050) in Human brain cells using Western Blot

Sample Type: Human brain

CFP antibody - N-terminal region (ARP56381_P050) in Human Tonsil cells using Immunohistochemistry

Sample Type: Human Tonsil

CFP antibody - middle region (ARP56382_P050) in Human Thymus cells using Western Blot

Sample Type: Human Thymus

CFP antibody - center region (OAAB06541) in CEM cells using Western Blot

Sample Type: CEM


CFP Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP56382 African elephant CFP antibody; Loxodonta africana CFP antibody G3STF5 93.0%
ARP56382 Bovine CFP antibody; Bos taurus CFP antibody Q17QC8 83.0%
ARP56382 Cat CFP antibody; Felis catus CFP antibody M3W950 86.0%
ARP56381 Chimpanzee CFP antibody; Pan troglodytes CFP antibody H2QYJ2 100.0%
ARP56382 Chimpanzee CFP antibody; Pan troglodytes CFP antibody H2QYJ2 100.0%
ARP56382 Dog CFP antibody; Canis familiaris CFP antibody E2RH18 79.0%
ARP56382 European domestic ferret CFP antibody; Mustela putorius furo CFP antibody M3YPN8 79.0%
ARP56382 Giant panda CFP antibody; Ailuropoda melanoleuca CFP antibody G1M2K7 92.0%
ARP56382 Guinea pig CFP antibody; Cavia porcellus CFP antibody Q64181 79.0%
ARP56382 Guinea pig CFP antibody; Cavia porcellus CFP antibody H0V9N6 79.0%
ARP56382 Guinea pig CFP antibody; Cavia porcellus CFP antibody H0W9U3 79.0%
ARP56382 Horse CFP antibody; Equus caballus CFP antibody F6SP74 86.0%
ARP56381 Human CFP antibody; Homo sapiens CFP antibody E9PAQ1 100.0%
ARP56381 Human CFP antibody; Homo sapiens CFP antibody P27918 100.0%
ARP56382 Human CFP antibody; Homo sapiens CFP antibody P27918 100.0%
ARP56382 Mouse CFP antibody; Mus musculus CFP antibody A2AE15 93.0%
ARP56382 Mouse CFP antibody; Mus musculus CFP antibody P11680 93.0%
ARP56382 Rabbit CFP antibody; Oryctolagus cuniculus CFP antibody G1U9S1 93.0%
ARP56382 Rat CFP antibody; Rattus norvegicus CFP antibody B0BNN4 93.0%
ARP56382 Rhesus macaque CFP antibody; Macaca mulatta CFP antibody H9Z2N8 100.0%
ARP56381 Rhesus macaque CFP antibody; Macaca mulatta CFP antibody H9Z2N8 79.0%
ARP56382 Small-eared galago CFP antibody; Otolemur garnettii CFP antibody H0X555 86.0%
ARP56382 Sumatran orangutan CFP antibody; Pongo abelii CFP antibody Q5RBP8 100.0%
ARP56381 Sumatran orangutan CFP antibody; Pongo abelii CFP antibody Q5RBP8 86.0%
ARP56382 Thirteen-lined ground squirrel CFP antibody; Spermophilus tridecemlineatus CFP antibody I3MEI1 86.0%
ARP56382 White-tufted-ear marmoset CFP antibody; Callithrix jacchus CFP antibody F7IDK9 86.0%
ARP56381 White-tufted-ear marmoset CFP antibody; Callithrix jacchus CFP antibody F7IDK9 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas206380_s_at721_B_lymphoblasts5.55035.580Details
BioGPS Gene Atlas206380_s_atAdipocyte5.25035.580Details
BioGPS Gene Atlas206380_s_atAdrenalCortex5.00035.580Details
BioGPS Gene Atlas206380_s_atAdrenalgland3.90035.580Details
BioGPS Gene Atlas206380_s_atAmygdala4.70035.580Details
BioGPS Gene Atlas206380_s_atAppendix4.65035.580Details
BioGPS Gene Atlas206380_s_atAtrioventricularNode3.65035.580Details
BioGPS Gene Atlas206380_s_atBDCA4+_DentriticCells223.30035.580Details
BioGPS Gene Atlas206380_s_atBonemarrow29.10035.580Details
BioGPS Gene Atlas206380_s_atBronchialEpithelialCells4.50035.580Details
BioGPS Gene Atlas206380_s_atCD105+_Endothelial16.05035.580Details
BioGPS Gene Atlas206380_s_atCD14+_Monocytes952.80035.580Details
BioGPS Gene Atlas206380_s_atCD19+_BCells(neg._sel.)4.90035.580Details
BioGPS Gene Atlas206380_s_atCD33+_Myeloid727.60035.580Details
BioGPS Gene Atlas206380_s_atCD34+11.25035.580Details
BioGPS Gene Atlas206380_s_atCD4+_Tcells5.35035.580Details
BioGPS Gene Atlas206380_s_atCD56+_NKCells13.45035.580Details
BioGPS Gene Atlas206380_s_atCD71+_EarlyErythroid4.35035.580Details
BioGPS Gene Atlas206380_s_atCD8+_Tcells4.35035.580Details
BioGPS Gene Atlas206380_s_atCardiacMyocytes5.75035.580Details
BioGPS Gene Atlas206380_s_atCaudatenucleus4.15035.580Details
BioGPS Gene Atlas206380_s_atCerebellum3.75035.580Details
BioGPS Gene Atlas206380_s_atCerebellumPeduncles5.25035.580Details
BioGPS Gene Atlas206380_s_atCiliaryGanglion3.30035.580Details
BioGPS Gene Atlas206380_s_atCingulateCortex7.75035.580Details
BioGPS Gene Atlas206380_s_atColorectaladenocarcinoma4.55035.580Details
BioGPS Gene Atlas206380_s_atDorsalRootGanglion3.60035.580Details
BioGPS Gene Atlas206380_s_atFetalThyroid4.45035.580Details
BioGPS Gene Atlas206380_s_atFetalbrain4.55035.580Details
BioGPS Gene Atlas206380_s_atFetalliver4.05035.580Details
BioGPS Gene Atlas206380_s_atFetallung4.25035.580Details
BioGPS Gene Atlas206380_s_atGlobusPallidus3.95035.580Details
BioGPS Gene Atlas206380_s_atHeart10.10035.580Details
BioGPS Gene Atlas206380_s_atHypothalamus4.90035.580Details
BioGPS Gene Atlas206380_s_atKidney3.80035.580Details
BioGPS Gene Atlas206380_s_atLeukemia_chronicMyelogenousK-5624.15035.580Details
BioGPS Gene Atlas206380_s_atLeukemia_promyelocytic-HL-604.05035.580Details
BioGPS Gene Atlas206380_s_atLeukemialymphoblastic(MOLT-4)3.60035.580Details
BioGPS Gene Atlas206380_s_atLiver13.95035.580Details
BioGPS Gene Atlas206380_s_atLung5.55035.580Details
BioGPS Gene Atlas206380_s_atLymphnode10.00035.580Details
BioGPS Gene Atlas206380_s_atLymphoma_burkitts(Daudi)5.90035.580Details
BioGPS Gene Atlas206380_s_atLymphoma_burkitts(Raji)6.35035.580Details
BioGPS Gene Atlas206380_s_atMedullaOblongata4.15035.580Details
BioGPS Gene Atlas206380_s_atOccipitalLobe4.10035.580Details
BioGPS Gene Atlas206380_s_atOlfactoryBulb3.65035.580Details
BioGPS Gene Atlas206380_s_atOvary3.10035.580Details
BioGPS Gene Atlas206380_s_atPancreas3.70035.580Details
BioGPS Gene Atlas206380_s_atPancreaticIslet4.90035.580Details
BioGPS Gene Atlas206380_s_atParietalLobe4.90035.580Details
BioGPS Gene Atlas206380_s_atPituitary5.50035.580Details
BioGPS Gene Atlas206380_s_atPlacenta4.75035.580Details
BioGPS Gene Atlas206380_s_atPons4.40035.580Details
BioGPS Gene Atlas206380_s_atPrefrontalCortex5.60035.580Details
BioGPS Gene Atlas206380_s_atProstate5.25035.580Details
BioGPS Gene Atlas206380_s_atSalivarygland3.70035.580Details
BioGPS Gene Atlas206380_s_atSkeletalMuscle5.30035.580Details
BioGPS Gene Atlas206380_s_atSkin3.55035.580Details
BioGPS Gene Atlas206380_s_atSmoothMuscle5.15035.580Details
BioGPS Gene Atlas206380_s_atSpinalcord4.90035.580Details
BioGPS Gene Atlas206380_s_atSubthalamicNucleus4.55035.580Details
BioGPS Gene Atlas206380_s_atSuperiorCervicalGanglion5.45035.580Details
BioGPS Gene Atlas206380_s_atTemporalLobe4.20035.580Details
BioGPS Gene Atlas206380_s_atTestis3.90035.580Details
BioGPS Gene Atlas206380_s_atTestisGermCell3.80035.580Details
BioGPS Gene Atlas206380_s_atTestisIntersitial3.80035.580Details
BioGPS Gene Atlas206380_s_atTestisLeydigCell4.55035.580Details
BioGPS Gene Atlas206380_s_atTestisSeminiferousTubule3.95035.580Details
BioGPS Gene Atlas206380_s_atThalamus4.65035.580Details
BioGPS Gene Atlas206380_s_atThymus3.70035.580Details
BioGPS Gene Atlas206380_s_atThyroid5.65035.580Details
BioGPS Gene Atlas206380_s_atTongue4.50035.580Details
BioGPS Gene Atlas206380_s_atTonsil4.45035.580Details
BioGPS Gene Atlas206380_s_atTrachea3.90035.580Details
BioGPS Gene Atlas206380_s_atTrigeminalGanglion4.70035.580Details
BioGPS Gene Atlas206380_s_atUterus3.70035.580Details
BioGPS Gene Atlas206380_s_atUterusCorpus4.10035.580Details
BioGPS Gene Atlas206380_s_atWholeBlood767.80035.580Details
BioGPS Gene Atlas206380_s_atWholebrain3.80035.580Details
BioGPS Gene Atlas206380_s_atcolon4.60035.580Details
BioGPS Gene Atlas206380_s_atpineal_day5.66035.580Details
BioGPS Gene Atlas206380_s_atpineal_night5.52035.580Details
BioGPS Gene Atlas206380_s_atretina5.47535.580Details
BioGPS Gene Atlas206380_s_atsmall_intestine4.35035.580Details
BioGPS NCI60206380_s_at7864.3054.190Details
BioGPS NCI60206380_s_atA1723.9734.190Details
BioGPS NCI60206380_s_atA2044.1544.190Details
BioGPS NCI60206380_s_atA3614.2264.190Details
BioGPS NCI60206380_s_atA4984.1734.190Details
BioGPS NCI60206380_s_atA5494.2474.190Details
BioGPS NCI60206380_s_atACC34.3984.190Details
BioGPS NCI60206380_s_atACHN3.9474.190Details
BioGPS NCI60206380_s_atALVA314.4704.190Details
BioGPS NCI60206380_s_atCAKI14.3484.190Details
BioGPS NCI60206380_s_atCCRT CEM4.7944.190Details
BioGPS NCI60206380_s_atCOLO2054.2114.190Details
BioGPS NCI60206380_s_atDLD14.0924.190Details
BioGPS NCI60206380_s_atDU1453.9944.190Details
BioGPS NCI60206380_s_atEKVX4.0114.190Details
BioGPS NCI60206380_s_atGM1334.2844.190Details
BioGPS NCI60206380_s_atGM16004.3854.190Details
BioGPS NCI60206380_s_atGM23134.2474.190Details
BioGPS NCI60206380_s_atGM23454.2024.190Details
BioGPS NCI60206380_s_atGM24934.4244.190Details
BioGPS NCI60206380_s_atGM974.6944.190Details
BioGPS NCI60206380_s_atHCC29983.8094.190Details
BioGPS NCI60206380_s_atHCT1164.1764.190Details
BioGPS NCI60206380_s_atHCT153.9564.190Details
BioGPS NCI60206380_s_atHEK 293 T-rex4.2804.190Details
BioGPS NCI60206380_s_atHEK 293T4.1544.190Details
BioGPS NCI60206380_s_atHEK2934.1444.190Details
BioGPS NCI60206380_s_atHELA3.9334.190Details
BioGPS NCI60206380_s_atHEPG24.1684.190Details
BioGPS NCI60206380_s_atHL604.3964.190Details
BioGPS NCI60206380_s_atHOP624.1964.190Details
BioGPS NCI60206380_s_atHOP924.1274.190Details
BioGPS NCI60206380_s_atHS578T4.1294.190Details
BioGPS NCI60206380_s_atHSG4.0734.190Details
BioGPS NCI60206380_s_atHT10804.1294.190Details
BioGPS NCI60206380_s_atHT294.4954.190Details
BioGPS NCI60206380_s_atIGROV14.1484.190Details
BioGPS NCI60206380_s_atIOSE804.1304.190Details
BioGPS NCI60206380_s_atJURKAT4.1704.190Details
BioGPS NCI60206380_s_atK5624.5024.190Details
BioGPS NCI60206380_s_atKM124.4294.190Details
BioGPS NCI60206380_s_atLN183.9254.190Details
BioGPS NCI60206380_s_atLNCAP4.1804.190Details
BioGPS NCI60206380_s_atLOX IMVI4.1674.190Details
BioGPS NCI60206380_s_atM144.1294.190Details
BioGPS NCI60206380_s_atMALME 3M4.4674.190Details
BioGPS NCI60206380_s_atMCF74.0254.190Details
BioGPS NCI60206380_s_atMD MB2314.2554.190Details
BioGPS NCI60206380_s_atMDA MB4354.4894.190Details
BioGPS NCI60206380_s_atMOLT44.3444.190Details
BioGPS NCI60206380_s_atNCI 4604.3074.190Details
BioGPS NCI60206380_s_atNCI H2264.2774.190Details
BioGPS NCI60206380_s_atNCI H234.1814.190Details
BioGPS NCI60206380_s_atNCI H322M4.1614.190Details
BioGPS NCI60206380_s_atNCVADR RES3.9244.190Details
BioGPS NCI60206380_s_atOVCAR34.4394.190Details
BioGPS NCI60206380_s_atOVCAR44.1654.190Details
BioGPS NCI60206380_s_atOVCAR54.0994.190Details
BioGPS NCI60206380_s_atOVCAR83.9004.190Details
BioGPS NCI60206380_s_atPANC14.2474.190Details
BioGPS NCI60206380_s_atRL74.2904.190Details
BioGPS NCI60206380_s_atRPMI 82264.2374.190Details
BioGPS NCI60206380_s_atRS118464.4054.190Details
BioGPS NCI60206380_s_atRXF3934.1454.190Details
BioGPS NCI60206380_s_atSAOS24.2304.190Details
BioGPS NCI60206380_s_atSF2684.1724.190Details
BioGPS NCI60206380_s_atSF2954.1364.190Details
BioGPS NCI60206380_s_atSF5393.9494.190Details
BioGPS NCI60206380_s_atSHSYSY+RA4.0444.190Details
BioGPS NCI60206380_s_atSHSYSY-RA4.1194.190Details
BioGPS NCI60206380_s_atSKMEL24.1574.190Details
BioGPS NCI60206380_s_atSKMEL284.1934.190Details
BioGPS NCI60206380_s_atSKMEL54.0364.190Details
BioGPS NCI60206380_s_atSKOV34.3374.190Details
BioGPS NCI60206380_s_atSN12C4.1344.190Details
BioGPS NCI60206380_s_atSNB193.9624.190Details
BioGPS NCI60206380_s_atSNB754.1504.190Details
BioGPS NCI60206380_s_atSR4.3164.190Details
BioGPS NCI60206380_s_atSW6204.2404.190Details
BioGPS NCI60206380_s_atT244.3034.190Details
BioGPS NCI60206380_s_atT3M44.3624.190Details
BioGPS NCI60206380_s_atTK104.1684.190Details
BioGPS NCI60206380_s_atU1184.0504.190Details
BioGPS NCI60206380_s_atU1383.9364.190Details
BioGPS NCI60206380_s_atU20S4.0454.190Details
BioGPS NCI60206380_s_atU2514.1014.190Details
BioGPS NCI60206380_s_atU874.0534.190Details
BioGPS NCI60206380_s_atUACC2574.0874.190Details
BioGPS NCI60206380_s_atUACC624.2184.190Details
BioGPS NCI60206380_s_atUO314.0354.190Details
BioGPS NCI60206380_s_atZR75_14.3044.190Details
BioGPS NCI60206380_s_atastrocytes4.1814.190Details
BioGPS NCI60206380_s_athuh-74.2944.190Details