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Gene ID: 1073 | CFL2 Antibody Resource


CFL2 Antibody Resource
Gene Full Name: 
cofilin 2 (muscle)
Uniprot: 
Q9Y281
Protein Name: 
cofilin-2
Nucleotide: 
NR_028131
Alias: 
NEM7;
Ensembl: 
ENSG00000165410
Location: 
14q12
HPRD: 
03262
NCBI Gene: 
1073
MIM: 
601443

Summary: 
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
Function: 
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods .
Subcellular location: 
Nucleus matrix. Cytoplasm › cytoskeleton.
PTM: 
Acetylation;
Disease: 
Nemaline myopathy 7 (NEM7) [MIM:610687]: A form of nemaline myopathy. Nemaline myopathies are muscular disorders characterized by muscle weakness of varying severity and onset, and abnormal thread-like or rod-shaped structures in muscle fibers on histologic examination. Nemaline myopathy type 7 presents at birth with hypotonia and generalized weakness. Major motor milestones are delayed, but independent ambulation is achieved. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OASA06111 CFL2 antibody - C-terminal region (OASA06111) Human ELISA, WB 0.1mg $530 Details
Polyclonal Antibody OAEB01156 CFL2 Antibody (OAEB01156) Guinea pig, Horse, Human, Mouse, Pig, Rat WB 0.1mg $289 Details
Polyclonal Antibody ARP48434_P050 Cfl2 Antibody - C-terminal region (ARP48434_P050) Guinea pig, Horse, Human, Mouse, Pig, Rat, Zebrafish WB 50ug $289 Details
Polyclonal Antibody ARP48433_P050 CFL2 Antibody (ARP48433_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep, Zebrafish Not tested 50 ug $125 Details
Polyclonal Antibody OAAB10417 CFL2 antibody - N - terminal region (OAAB10417) Human WB, IHC 400ul $289 Details
Polyclonal Antibody OAGA00022 CFL2 antibody (OAGA00022) Polyclonal Human ICC/IF, IHC (Formalin-fixed paraffin-embedded sections), WB 100 ul $340 Details
Polyclonal Antibody OAGA01036 CFL2 antibody (OAGA01036) Polyclonal Human, Mouse ICC/IF, WB 100 ul $340 Details

Show all CFL2 antibodies


Product Images
Cfl2 Antibody - C-terminal region (ARP48434_P050) in Mouse Liver cells using Western Blot

Sample Type: Mouse Liver

CFL2 antibody - N - terminal region (OAAB10417) in 293 cells using Western Blot

Sample Type: 293

CFL2 antibody - N - terminal region (OAAB10417) in Human Rectum cells using Immunohistochemistry

Sample Type: Human Rectum

CFL2 antibody - N - terminal region (OAAB10417) in Human Uterus cells using Western Blot

Sample Type: Human Uterus

CFL2 Antibody (OAEB01156) in Ratkeletal Muscle cells using Western Blot

Sample Type: Ratkeletal Muscle


CFL2 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP48307 African clawed frog CFL2 antibody; Xenopus laevis CFL2 antibody Q5XHH8 100.0%
ARP48433 African clawed frog CFL2 antibody; Xenopus laevis CFL2 antibody Q5XHH8 100.0%
ARP48434 African clawed frog CFL2 antibody; Xenopus laevis CFL2 antibody Q5XHH8 79.0%
ARP48433 Bovine CFL2 antibody; Bos taurus CFL2 antibody Q148F1 100.0%
ARP48434 Bovine CFL2 antibody; Bos taurus CFL2 antibody Q148F1 100.0%
ARP48307 Bovine CFL2 antibody; Bos taurus CFL2 antibody Q148F1 92.0%
ARP48433 Cat CFL2 antibody; Felis catus CFL2 antibody M3W9N7 100.0%
ARP48434 Cat CFL2 antibody; Felis catus CFL2 antibody M3W9N7 100.0%
ARP48307 Cat CFL2 antibody; Felis catus CFL2 antibody M3W9N7 92.0%
ARP48307 Chicken CFL2 antibody; Gallus gallus CFL2 antibody P21566 100.0%
ARP48433 Chicken CFL2 antibody; Gallus gallus CFL2 antibody P21566 100.0%
ARP48434 Chicken CFL2 antibody; Gallus gallus CFL2 antibody P21566 100.0%
ARP48433 Chimpanzee CFL2 antibody; Pan troglodytes CFL2 antibody H2Q860 100.0%
ARP48434 Chimpanzee CFL2 antibody; Pan troglodytes CFL2 antibody H2Q860 100.0%
ARP48307 Chimpanzee CFL2 antibody; Pan troglodytes CFL2 antibody H2Q860 92.0%
ARP48433 Chinese softshell turtle CFL2 antibody; Pelodiscus sinensis CFL2 antibody K7GHS6 100.0%
ARP48434 Chinese softshell turtle CFL2 antibody; Pelodiscus sinensis CFL2 antibody K7GHS6 100.0%
ARP48307 Chinese softshell turtle CFL2 antibody; Pelodiscus sinensis CFL2 antibody K7GHS6 92.0%
ARP48307 Collared flycatcher CFL2 antibody; Ficedula albicollis CFL2 antibody U3JTX3 100.0%
ARP48433 Collared flycatcher CFL2 antibody; Ficedula albicollis CFL2 antibody U3JTX3 100.0%
ARP48434 Collared flycatcher CFL2 antibody; Ficedula albicollis CFL2 antibody U3JTX3 100.0%
ARP48433 Dog CFL2 antibody; Canis familiaris CFL2 antibody J9P2G7 100.0%
ARP48434 Dog CFL2 antibody; Canis familiaris CFL2 antibody J9P2G7 100.0%
ARP48307 Dog CFL2 antibody; Canis familiaris CFL2 antibody J9P2G7 92.0%
ARP48307 Domestic duck CFL2 antibody; Anas platyrhynchos CFL2 antibody R0K0M8 100.0%
ARP48433 Domestic duck CFL2 antibody; Anas platyrhynchos CFL2 antibody R0K0M8 100.0%
ARP48434 Domestic duck CFL2 antibody; Anas platyrhynchos CFL2 antibody R0K0M8 100.0%
ARP48307 Duckbill platypus CFL2 antibody; Ornithorhynchus anatinus CFL2 antibody F6PGG2 100.0%
ARP48433 Duckbill platypus CFL2 antibody; Ornithorhynchus anatinus CFL2 antibody F6PGG2 100.0%
ARP48434 Duckbill platypus CFL2 antibody; Ornithorhynchus anatinus CFL2 antibody F6PGG2 100.0%
ARP48433 European domestic ferret CFL2 antibody; Mustela putorius furo CFL2 antibody M3YXZ3 100.0%
ARP48434 European domestic ferret CFL2 antibody; Mustela putorius furo CFL2 antibody M3YXZ3 100.0%
ARP48307 European domestic ferret CFL2 antibody; Mustela putorius furo CFL2 antibody M3YXZ3 92.0%
ARP48433 Giant panda CFL2 antibody; Ailuropoda melanoleuca CFL2 antibody D2HKH6 100.0%
ARP48434 Giant panda CFL2 antibody; Ailuropoda melanoleuca CFL2 antibody D2HKH6 100.0%
ARP48307 Giant panda CFL2 antibody; Ailuropoda melanoleuca CFL2 antibody D2HKH6 92.0%
ARP48433 Horse CFL2 antibody; Equus caballus CFL2 antibody F7CT91 100.0%
ARP48434 Horse CFL2 antibody; Equus caballus CFL2 antibody F7CT91 100.0%
ARP48307 Horse CFL2 antibody; Equus caballus CFL2 antibody F7CT91 92.0%
ARP48433 Human CFL2 antibody; Homo sapiens CFL2 antibody Q549N0 100.0%
ARP48434 Human CFL2 antibody; Homo sapiens CFL2 antibody Q549N0 100.0%
ARP48433 Human CFL2 antibody; Homo sapiens CFL2 antibody Q9Y281-3 100.0%
ARP48434 Human CFL2 antibody; Homo sapiens CFL2 antibody Q9Y281-3 100.0%
ARP48433 Human CFL2 antibody; Homo sapiens CFL2 antibody Q9Y281 100.0%
ARP48434 Human CFL2 antibody; Homo sapiens CFL2 antibody Q9Y281 100.0%
ARP48307 Human CFL2 antibody; Homo sapiens CFL2 antibody Q549N0 92.0%
ARP48307 Human CFL2 antibody; Homo sapiens CFL2 antibody Q9Y281-3 92.0%
ARP48307 Human CFL2 antibody; Homo sapiens CFL2 antibody Q9Y281 92.0%
ARP48307 Human CFL2 antibody; Homo sapiens CFL2 antibody F8WDN3 92.0%
ARP48433 Mouse CFL2 antibody; Mus musculus CFL2 antibody P45591 100.0%
ARP48434 Mouse CFL2 antibody; Mus musculus CFL2 antibody P45591 100.0%
ARP48433 Mouse CFL2 antibody; Mus musculus CFL2 antibody Q3UHW9 100.0%
ARP48434 Mouse CFL2 antibody; Mus musculus CFL2 antibody Q3UHW9 100.0%
ARP48307 Mouse CFL2 antibody; Mus musculus CFL2 antibody P45591 92.0%
ARP48307 Mouse CFL2 antibody; Mus musculus CFL2 antibody Q3UHW9 92.0%
ARP48433 Pig CFL2 antibody; Sus scrofa CFL2 antibody Q5G6V9 100.0%
ARP48434 Pig CFL2 antibody; Sus scrofa CFL2 antibody Q5G6V9 100.0%
ARP48307 Pig CFL2 antibody; Sus scrofa CFL2 antibody Q5G6V9 92.0%
ARP48433 Rabbit CFL2 antibody; Oryctolagus cuniculus CFL2 antibody G1SX37 100.0%
ARP48307 Rabbit CFL2 antibody; Oryctolagus cuniculus CFL2 antibody G1SX37 92.0%
ARP48433 Rat CFL2 antibody; Rattus norvegicus CFL2 antibody M0RC65 100.0%
ARP48434 Rat CFL2 antibody; Rattus norvegicus CFL2 antibody M0RC65 100.0%
ARP48307 Rat CFL2 antibody; Rattus norvegicus CFL2 antibody M0RC65 92.0%
ARP48433 Rhesus macaque CFL2 antibody; Macaca mulatta CFL2 antibody F7H8A1 100.0%
ARP48434 Rhesus macaque CFL2 antibody; Macaca mulatta CFL2 antibody F7H8A1 100.0%
ARP48433 Rhesus macaque CFL2 antibody; Macaca mulatta CFL2 antibody G7MXF7 100.0%
ARP48434 Rhesus macaque CFL2 antibody; Macaca mulatta CFL2 antibody G7MXF7 100.0%
ARP48307 Rhesus macaque CFL2 antibody; Macaca mulatta CFL2 antibody F7H8A1 92.0%
ARP48307 Rhesus macaque CFL2 antibody; Macaca mulatta CFL2 antibody G7MXF7 92.0%
ARP48434 Small-eared galago CFL2 antibody; Otolemur garnettii CFL2 antibody H0XNY0 100.0%
ARP48433 Small-eared galago CFL2 antibody; Otolemur garnettii CFL2 antibody H0XNY0 100.0%
ARP48307 Small-eared galago CFL2 antibody; Otolemur garnettii CFL2 antibody H0XNY0 92.0%
ARP48433 Spotted green pufferfish CFL2 antibody; Tetraodon nigroviridis CFL2 antibody H3C528 100.0%
ARP48307 Spotted green pufferfish CFL2 antibody; Tetraodon nigroviridis CFL2 antibody H3C528 92.0%
ARP48433 Sumatran orangutan CFL2 antibody; Pongo abelii CFL2 antibody H2NL04 100.0%
ARP48434 Sumatran orangutan CFL2 antibody; Pongo abelii CFL2 antibody H2NL04 100.0%
ARP48307 Sumatran orangutan CFL2 antibody; Pongo abelii CFL2 antibody H2NL04 92.0%
ARP48433 Tasmanian devil CFL2 antibody; Sarcophilus harrisii CFL2 antibody G3VQG1 100.0%
ARP48434 Tasmanian devil CFL2 antibody; Sarcophilus harrisii CFL2 antibody G3VQG1 100.0%
ARP48307 Tasmanian devil CFL2 antibody; Sarcophilus harrisii CFL2 antibody G3VQG1 92.0%
ARP48433 Thirteen-lined ground squirrel CFL2 antibody; Spermophilus tridecemlineatus CFL2 antibody I3LZ05 100.0%
ARP48434 Thirteen-lined ground squirrel CFL2 antibody; Spermophilus tridecemlineatus CFL2 antibody I3LZ05 100.0%
ARP48307 Thirteen-lined ground squirrel CFL2 antibody; Spermophilus tridecemlineatus CFL2 antibody I3LZ05 92.0%
ARP48307 Western clawed frog CFL2 antibody; Xenopus tropicalis CFL2 antibody Q5U4Y2 100.0%
ARP48433 Western clawed frog CFL2 antibody; Xenopus tropicalis CFL2 antibody Q5U4Y2 100.0%
ARP48434 Western clawed frog CFL2 antibody; Xenopus tropicalis CFL2 antibody Q5U4Y2 79.0%
ARP48433 White-tufted-ear marmoset CFL2 antibody; Callithrix jacchus CFL2 antibody F7DMB4 100.0%
ARP48434 White-tufted-ear marmoset CFL2 antibody; Callithrix jacchus CFL2 antibody F7DMB4 100.0%
ARP48307 White-tufted-ear marmoset CFL2 antibody; Callithrix jacchus CFL2 antibody F7DMB4 92.0%
ARP48307 Zebra finch CFL2 antibody; Taeniopygia guttata CFL2 antibody H0ZNW4 100.0%
ARP48433 Zebra finch CFL2 antibody; Taeniopygia guttata CFL2 antibody H0ZNW4 100.0%
ARP48434 Zebra finch CFL2 antibody; Taeniopygia guttata CFL2 antibody H0ZNW4 100.0%
ARP48433 Zebrafish CFL2 antibody; Danio rerio CFL2 antibody Q6NZW3 100.0%
ARP48434 Zebrafish CFL2 antibody; Danio rerio CFL2 antibody Q6NZW3 86.0%

Tissue & Cell Line Gene Expression Data