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Gene ID: 1675 | CFD Antibody Resource


CFD Antibody Resource
Gene Full Name: 
complement factor D (adipsin)
Uniprot: 
P00746
Protein Name: 
complement factor D
Nucleotide: 
NM_001928
Alias: 
DF;ADN;PFD;ADIPSIN;
Ensembl: 
Location: 
19p13.3
HPRD: 
00600
NCBI Gene: 
1675
MIM: 
134350

Summary: 
The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. [provided by RefSeq, Jul 2008]
Function: 
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
Subcellular location: 
Secreted.
PTM: 
Disulfide bond;
Disease: 
Complement factor D deficiency (CFDD) [MIM:613912]: An immunologic disorder characterized by increased susceptibility to bacterial infections, particularly Neisseria infections, due to a defect in the alternative complement pathway. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP60174_P050 CFD antibody - C-terminal region (ARP60174_P050) Polyclonal Guinea pig, Human, Mouse, Rat WB 50ug $289 Details
Polyclonal Antibody ARP60173_P050 CFD Antibody (ARP60173_P050) Polyclonal Bovine, Dog, Guinea pig, Human, Mouse, Pig, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB08330 CFD antibody - N - terminal region (OAAB08330) Human WB, IHC 400ul $289 Details

Show all CFD antibodies


Product Images
CFD antibody - C-terminal region (ARP60174_P050) in Human Lung cells using Western Blot

Sample Type: Human Lung

CFD antibody - N - terminal region (OAAB08330) in A549 cells using Western Blot

Sample Type: A549

CFD antibody - N - terminal region (OAAB08330) in Human bladder cells using Immunohistochemistry

Sample Type: Human bladder


CFD Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP60174 Bovine CFD antibody; Bos taurus CFD antibody Q3T0A3 93.0%
ARP60173 Bovine CFD antibody; Bos taurus CFD antibody Q3T0A3 86.0%
ARP60173 Chimpanzee CFD antibody; Pan troglodytes CFD antibody H2R6K0 100.0%
ARP60174 Chimpanzee CFD antibody; Pan troglodytes CFD antibody H2R6K0 100.0%
ARP60173 Dog CFD antibody; Canis familiaris CFD antibody J9P5F0 100.0%
ARP60174 Dog CFD antibody; Canis familiaris CFD antibody J9P5F0 100.0%
ARP60173 Duckbill platypus CFD antibody; Ornithorhynchus anatinus CFD antibody F6W0D1 86.0%
ARP60173 Human CFD antibody; Homo sapiens CFD antibody K7ERG9 100.0%
ARP60174 Human CFD antibody; Homo sapiens CFD antibody K7ERG9 100.0%
ARP60173 Human CFD antibody; Homo sapiens CFD antibody P00746 100.0%
ARP60174 Human CFD antibody; Homo sapiens CFD antibody P00746 100.0%
ARP60174 Mouse CFD antibody; Mus musculus CFD antibody Q3UP47 86.0%
ARP60174 Mouse CFD antibody; Mus musculus CFD antibody B7ZNS9 86.0%
ARP60174 Mouse CFD antibody; Mus musculus CFD antibody P03953-2 86.0%
ARP60174 Mouse CFD antibody; Mus musculus CFD antibody P03953 86.0%
ARP60173 Mouse CFD antibody; Mus musculus CFD antibody Q3UP47 79.0%
ARP60173 Mouse CFD antibody; Mus musculus CFD antibody B7ZNS9 79.0%
ARP60173 Mouse CFD antibody; Mus musculus CFD antibody P03953-2 79.0%
ARP60173 Mouse CFD antibody; Mus musculus CFD antibody P03953 79.0%
ARP60174 Pig CFD antibody; Sus scrofa CFD antibody P51779 100.0%
ARP60173 Pig CFD antibody; Sus scrofa CFD antibody P51779 93.0%
ARP60174 Rat CFD antibody; Rattus norvegicus CFD antibody G3V7H3 86.0%
ARP60174 Rat CFD antibody; Rattus norvegicus CFD antibody P32038 86.0%
ARP60173 Rhesus macaque CFD antibody; Macaca mulatta CFD antibody H9EXC1 100.0%
ARP60174 Rhesus macaque CFD antibody; Macaca mulatta CFD antibody H9EXC1 100.0%
ARP60173 Siberian tiger CFD antibody; Panthera tigris altaica CFD antibody T1W3L7 93.0%
ARP60174 Siberian tiger CFD antibody; Panthera tigris altaica CFD antibody T1W3L7 92.0%
ARP60173 Small-eared galago CFD antibody; Otolemur garnettii CFD antibody H0XZ59 100.0%
ARP60174 Small-eared galago CFD antibody; Otolemur garnettii CFD antibody H0XZ59 93.0%
ARP60173 Sumatran orangutan CFD antibody; Pongo abelii CFD antibody H2NWR7 100.0%
ARP60174 Sumatran orangutan CFD antibody; Pongo abelii CFD antibody H2NWR7 100.0%
ARP60173 Thirteen-lined ground squirrel CFD antibody; Spermophilus tridecemlineatus CFD antibody I3MZR5 100.0%
ARP60174 Thirteen-lined ground squirrel CFD antibody; Spermophilus tridecemlineatus CFD antibody I3MZR5 93.0%
ARP60173 White-tufted-ear marmoset CFD antibody; Callithrix jacchus CFD antibody U3C211 100.0%
ARP60174 White-tufted-ear marmoset CFD antibody; Callithrix jacchus CFD antibody U3C211 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas205382_s_at721_B_lymphoblasts6.450145.110Details
BioGPS Gene Atlas205382_s_atAdipocyte1318.700145.110Details
BioGPS Gene Atlas205382_s_atAdrenalCortex22.700145.110Details
BioGPS Gene Atlas205382_s_atAdrenalgland42.900145.110Details
BioGPS Gene Atlas205382_s_atAmygdala5.850145.110Details
BioGPS Gene Atlas205382_s_atAppendix782.250145.110Details
BioGPS Gene Atlas205382_s_atAtrioventricularNode56.600145.110Details
BioGPS Gene Atlas205382_s_atBDCA4+_DentriticCells44.950145.110Details
BioGPS Gene Atlas205382_s_atBonemarrow61.650145.110Details
BioGPS Gene Atlas205382_s_atBronchialEpithelialCells5.150145.110Details
BioGPS Gene Atlas205382_s_atCD105+_Endothelial151.000145.110Details
BioGPS Gene Atlas205382_s_atCD14+_Monocytes821.950145.110Details
BioGPS Gene Atlas205382_s_atCD19+_BCells(neg._sel.)6.100145.110Details
BioGPS Gene Atlas205382_s_atCD33+_Myeloid765.700145.110Details
BioGPS Gene Atlas205382_s_atCD34+119.150145.110Details
BioGPS Gene Atlas205382_s_atCD4+_Tcells9.250145.110Details
BioGPS Gene Atlas205382_s_atCD56+_NKCells104.900145.110Details
BioGPS Gene Atlas205382_s_atCD71+_EarlyErythroid9.750145.110Details
BioGPS Gene Atlas205382_s_atCD8+_Tcells7.900145.110Details
BioGPS Gene Atlas205382_s_atCardiacMyocytes8.700145.110Details
BioGPS Gene Atlas205382_s_atCaudatenucleus5.900145.110Details
BioGPS Gene Atlas205382_s_atCerebellum6.000145.110Details
BioGPS Gene Atlas205382_s_atCerebellumPeduncles6.550145.110Details
BioGPS Gene Atlas205382_s_atCiliaryGanglion110.750145.110Details
BioGPS Gene Atlas205382_s_atCingulateCortex7.650145.110Details
BioGPS Gene Atlas205382_s_atColorectaladenocarcinoma9.400145.110Details
BioGPS Gene Atlas205382_s_atDorsalRootGanglion51.700145.110Details
BioGPS Gene Atlas205382_s_atFetalThyroid267.900145.110Details
BioGPS Gene Atlas205382_s_atFetalbrain6.350145.110Details
BioGPS Gene Atlas205382_s_atFetalliver5.000145.110Details
BioGPS Gene Atlas205382_s_atFetallung63.450145.110Details
BioGPS Gene Atlas205382_s_atGlobusPallidus5.600145.110Details
BioGPS Gene Atlas205382_s_atHeart1739.800145.110Details
BioGPS Gene Atlas205382_s_atHypothalamus6.700145.110Details
BioGPS Gene Atlas205382_s_atKidney7.450145.110Details
BioGPS Gene Atlas205382_s_atLeukemia_chronicMyelogenousK-5629.050145.110Details
BioGPS Gene Atlas205382_s_atLeukemia_promyelocytic-HL-605.550145.110Details
BioGPS Gene Atlas205382_s_atLeukemialymphoblastic(MOLT-4)5.700145.110Details
BioGPS Gene Atlas205382_s_atLiver10.000145.110Details
BioGPS Gene Atlas205382_s_atLung1114.500145.110Details
BioGPS Gene Atlas205382_s_atLymphnode149.700145.110Details
BioGPS Gene Atlas205382_s_atLymphoma_burkitts(Daudi)9.500145.110Details
BioGPS Gene Atlas205382_s_atLymphoma_burkitts(Raji)7.650145.110Details
BioGPS Gene Atlas205382_s_atMedullaOblongata4.900145.110Details
BioGPS Gene Atlas205382_s_atOccipitalLobe5.750145.110Details
BioGPS Gene Atlas205382_s_atOlfactoryBulb7.450145.110Details
BioGPS Gene Atlas205382_s_atOvary67.850145.110Details
BioGPS Gene Atlas205382_s_atPancreas30.050145.110Details
BioGPS Gene Atlas205382_s_atPancreaticIslet53.700145.110Details
BioGPS Gene Atlas205382_s_atParietalLobe5.150145.110Details
BioGPS Gene Atlas205382_s_atPituitary7.800145.110Details
BioGPS Gene Atlas205382_s_atPlacenta89.450145.110Details
BioGPS Gene Atlas205382_s_atPons7.200145.110Details
BioGPS Gene Atlas205382_s_atPrefrontalCortex7.000145.110Details
BioGPS Gene Atlas205382_s_atProstate320.250145.110Details
BioGPS Gene Atlas205382_s_atSalivarygland57.100145.110Details
BioGPS Gene Atlas205382_s_atSkeletalMuscle189.800145.110Details
BioGPS Gene Atlas205382_s_atSkin396.600145.110Details
BioGPS Gene Atlas205382_s_atSmoothMuscle8.150145.110Details
BioGPS Gene Atlas205382_s_atSpinalcord7.250145.110Details
BioGPS Gene Atlas205382_s_atSubthalamicNucleus8.650145.110Details
BioGPS Gene Atlas205382_s_atSuperiorCervicalGanglion9.050145.110Details
BioGPS Gene Atlas205382_s_atTemporalLobe5.300145.110Details
BioGPS Gene Atlas205382_s_atTestis59.350145.110Details
BioGPS Gene Atlas205382_s_atTestisGermCell175.950145.110Details
BioGPS Gene Atlas205382_s_atTestisIntersitial252.050145.110Details
BioGPS Gene Atlas205382_s_atTestisLeydigCell34.200145.110Details
BioGPS Gene Atlas205382_s_atTestisSeminiferousTubule43.350145.110Details
BioGPS Gene Atlas205382_s_atThalamus7.250145.110Details
BioGPS Gene Atlas205382_s_atThymus241.800145.110Details
BioGPS Gene Atlas205382_s_atThyroid719.900145.110Details
BioGPS Gene Atlas205382_s_atTongue390.050145.110Details
BioGPS Gene Atlas205382_s_atTonsil7.350145.110Details
BioGPS Gene Atlas205382_s_atTrachea161.050145.110Details
BioGPS Gene Atlas205382_s_atTrigeminalGanglion9.000145.110Details
BioGPS Gene Atlas205382_s_atUterus69.650145.110Details
BioGPS Gene Atlas205382_s_atUterusCorpus49.850145.110Details
BioGPS Gene Atlas205382_s_atWholeBlood481.850145.110Details
BioGPS Gene Atlas205382_s_atWholebrain5.100145.110Details
BioGPS Gene Atlas205382_s_atcolon399.350145.110Details
BioGPS Gene Atlas205382_s_atpineal_day8.060145.110Details
BioGPS Gene Atlas205382_s_atpineal_night6.560145.110Details
BioGPS Gene Atlas205382_s_atretina41.975145.110Details
BioGPS Gene Atlas205382_s_atsmall_intestine290.100145.110Details
BioGPS NCI60205382_s_at7865.43621.510Details
BioGPS NCI60205382_s_atA17230.47821.510Details
BioGPS NCI60205382_s_atA2045.81821.510Details
BioGPS NCI60205382_s_atA3617.24521.510Details
BioGPS NCI60205382_s_atA4986.42121.510Details
BioGPS NCI60205382_s_atA5495.71021.510Details
BioGPS NCI60205382_s_atACC3380.91421.510Details
BioGPS NCI60205382_s_atACHN5.51021.510Details
BioGPS NCI60205382_s_atALVA315.81721.510Details
BioGPS NCI60205382_s_atCAKI15.55421.510Details
BioGPS NCI60205382_s_atCCRT CEM5.92421.510Details
BioGPS NCI60205382_s_atCOLO2055.57921.510Details
BioGPS NCI60205382_s_atDLD141.50021.510Details
BioGPS NCI60205382_s_atDU1455.99721.510Details
BioGPS NCI60205382_s_atEKVX64.33021.510Details
BioGPS NCI60205382_s_atGM1335.36921.510Details
BioGPS NCI60205382_s_atGM16005.56021.510Details
BioGPS NCI60205382_s_atGM23134.86121.510Details
BioGPS NCI60205382_s_atGM23455.46021.510Details
BioGPS NCI60205382_s_atGM24935.63521.510Details
BioGPS NCI60205382_s_atGM975.85621.510Details
BioGPS NCI60205382_s_atHCC299854.38021.510Details
BioGPS NCI60205382_s_atHCT116274.01721.510Details
BioGPS NCI60205382_s_atHCT156.59121.510Details
BioGPS NCI60205382_s_atHEK 293 T-rex5.67621.510Details
BioGPS NCI60205382_s_atHEK 293T10.04921.510Details
BioGPS NCI60205382_s_atHEK2935.54821.510Details
BioGPS NCI60205382_s_atHELA59.15721.510Details
BioGPS NCI60205382_s_atHEPG25.63421.510Details
BioGPS NCI60205382_s_atHL605.96321.510Details
BioGPS NCI60205382_s_atHOP625.21121.510Details
BioGPS NCI60205382_s_atHOP925.35821.510Details
BioGPS NCI60205382_s_atHS578T5.09521.510Details
BioGPS NCI60205382_s_atHSG155.10421.510Details
BioGPS NCI60205382_s_atHT10805.11121.510Details
BioGPS NCI60205382_s_atHT295.86821.510Details
BioGPS NCI60205382_s_atIGROV195.75321.510Details
BioGPS NCI60205382_s_atIOSE804.87221.510Details
BioGPS NCI60205382_s_atJURKAT14.70021.510Details
BioGPS NCI60205382_s_atK56219.22221.510Details
BioGPS NCI60205382_s_atKM125.70321.510Details
BioGPS NCI60205382_s_atLN185.52921.510Details
BioGPS NCI60205382_s_atLNCAP5.61421.510Details
BioGPS NCI60205382_s_atLOX IMVI5.42021.510Details
BioGPS NCI60205382_s_atM145.16621.510Details
BioGPS NCI60205382_s_atMALME 3M5.75421.510Details
BioGPS NCI60205382_s_atMCF74.57021.510Details
BioGPS NCI60205382_s_atMD MB2315.89821.510Details
BioGPS NCI60205382_s_atMDA MB4355.68021.510Details
BioGPS NCI60205382_s_atMOLT45.52221.510Details
BioGPS NCI60205382_s_atNCI 4605.69921.510Details
BioGPS NCI60205382_s_atNCI H2265.67021.510Details
BioGPS NCI60205382_s_atNCI H2316.82821.510Details
BioGPS NCI60205382_s_atNCI H322M6.06521.510Details
BioGPS NCI60205382_s_atNCVADR RES29.62021.510Details
BioGPS NCI60205382_s_atOVCAR358.33621.510Details
BioGPS NCI60205382_s_atOVCAR47.80121.510Details
BioGPS NCI60205382_s_atOVCAR55.47921.510Details
BioGPS NCI60205382_s_atOVCAR87.81721.510Details
BioGPS NCI60205382_s_atPANC113.84521.510Details
BioGPS NCI60205382_s_atRL75.50421.510Details
BioGPS NCI60205382_s_atRPMI 82265.65921.510Details
BioGPS NCI60205382_s_atRS118465.63421.510Details
BioGPS NCI60205382_s_atRXF3934.70221.510Details
BioGPS NCI60205382_s_atSAOS213.24621.510Details
BioGPS NCI60205382_s_atSF2685.45121.510Details
BioGPS NCI60205382_s_atSF2955.49721.510Details
BioGPS NCI60205382_s_atSF5395.23721.510Details
BioGPS NCI60205382_s_atSHSYSY+RA5.32621.510Details
BioGPS NCI60205382_s_atSHSYSY-RA5.39621.510Details
BioGPS NCI60205382_s_atSKMEL25.64321.510Details
BioGPS NCI60205382_s_atSKMEL285.46921.510Details
BioGPS NCI60205382_s_atSKMEL55.78921.510Details
BioGPS NCI60205382_s_atSKOV325.58921.510Details
BioGPS NCI60205382_s_atSN12C5.64821.510Details
BioGPS NCI60205382_s_atSNB1916.23521.510Details
BioGPS NCI60205382_s_atSNB755.43221.510Details
BioGPS NCI60205382_s_atSR5.50821.510Details
BioGPS NCI60205382_s_atSW6205.48221.510Details
BioGPS NCI60205382_s_atT245.39121.510Details
BioGPS NCI60205382_s_atT3M4144.34321.510Details
BioGPS NCI60205382_s_atTK105.44921.510Details
BioGPS NCI60205382_s_atU1185.03421.510Details
BioGPS NCI60205382_s_atU1384.38821.510Details
BioGPS NCI60205382_s_atU20S5.73821.510Details
BioGPS NCI60205382_s_atU2515.38621.510Details
BioGPS NCI60205382_s_atU874.66421.510Details
BioGPS NCI60205382_s_atUACC2575.37521.510Details
BioGPS NCI60205382_s_atUACC625.50021.510Details
BioGPS NCI60205382_s_atUO314.99721.510Details
BioGPS NCI60205382_s_atZR75_113.84121.510Details
BioGPS NCI60205382_s_atastrocytes5.00921.510Details
BioGPS NCI60205382_s_athuh-75.43921.510Details