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Gene ID: 1069 | CETN2 Antibody Resource


CETN2 Antibody Resource
Gene Full Name: 
centrin, EF-hand protein, 2
Uniprot: 
P41208
Protein Name: 
centrin-2
Nucleotide: 
NM_004344
Alias: 
CALT;CEN2;
Ensembl: 
Location: 
Xq28
HPRD: 
02051
NCBI Gene: 
1069
MIM: 
300006

Summary: 
Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq, Jul 2008]
Function: 
Plays a fundamental role in microtubule organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CEP110. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with RAD23B appears to stabilize XPC. In vitro, stimulates DNA binding of the XPC:RAD23B dimer. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair.
Subcellular location: 
Cytoplasm › cytoskeleton › microtubule organizing center › centrosome › centriole. Nucleus Probable. Note: Centrosome of S-phase, interphase and mitotic cells.
PTM: 
Acetylation;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Others OPPA00045 CETN2 Human - Recombinant Human Centrin-2 (2ug) 2ug $100 Details
Polyclonal Antibody ARP60115_P050 CETN2 Antibody (ARP60115_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep, Zebrafish Not tested 50 ug $125 Details

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Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP60115 Bovine CETN2 antibody; Bos taurus CETN2 antibody Q2TBN3 100.0%
ARP52017 Bovine CETN2 antibody; Bos taurus CETN2 antibody Q2TBN3 86.0%
ARP60115 Cat CETN2 antibody; Felis catus CETN2 antibody M3W326 100.0%
ARP52017 Cat CETN2 antibody; Felis catus CETN2 antibody M3W326 86.0%
ARP52017 Chicken CETN2 antibody; Gallus gallus CETN2 antibody F1NM71 86.0%
ARP60115 Chicken CETN2 antibody; Gallus gallus CETN2 antibody F1NM71 86.0%
ARP52018 Chicken CETN2 antibody; Gallus gallus CETN2 antibody F1NM71 79.0%
ARP60115 Chimpanzee CETN2 antibody; Pan troglodytes CETN2 antibody H2QZ91 100.0%
ARP52017 Chimpanzee CETN2 antibody; Pan troglodytes CETN2 antibody H2QZ91 86.0%
ARP60115 European domestic ferret CETN2 antibody; Mustela putorius furo CETN2 antibody M3YKA8 100.0%
ARP52017 European domestic ferret CETN2 antibody; Mustela putorius furo CETN2 antibody M3YKA8 86.0%
ARP60115 Giant panda CETN2 antibody; Ailuropoda melanoleuca CETN2 antibody G1L0I0 100.0%
ARP52017 Giant panda CETN2 antibody; Ailuropoda melanoleuca CETN2 antibody G1L0I0 86.0%
ARP60115 Honeybee CETN2 antibody; Apis mellifera CETN2 antibody H9JZC2 83.0%
ARP60115 Horse CETN2 antibody; Equus caballus CETN2 antibody F7DSU8 100.0%
ARP52017 Horse CETN2 antibody; Equus caballus CETN2 antibody F7DSU8 79.0%
ARP60115 Human CETN2 antibody; Homo sapiens CETN2 antibody P41208 100.0%
ARP52017 Human CETN2 antibody; Homo sapiens CETN2 antibody P41208 86.0%
ARP60115 Mouse CETN2 antibody; Mus musculus CETN2 antibody B1AUQ7 100.0%
ARP60115 Mouse CETN2 antibody; Mus musculus CETN2 antibody Q9R1K9 100.0%
ARP52017 Mouse CETN2 antibody; Mus musculus CETN2 antibody B1AUQ7 93.0%
ARP52017 Mouse CETN2 antibody; Mus musculus CETN2 antibody Q9R1K9 93.0%
ARP60115 Pig CETN2 antibody; Sus scrofa CETN2 antibody K7GP26 100.0%
ARP60115 Pig CETN2 antibody; Sus scrofa CETN2 antibody K7GR44 100.0%
ARP60115 Pig CETN2 antibody; Sus scrofa CETN2 antibody F2Z563 100.0%
ARP52017 Pig CETN2 antibody; Sus scrofa CETN2 antibody K7GPA3 86.0%
ARP52017 Pig CETN2 antibody; Sus scrofa CETN2 antibody K7GR44 86.0%
ARP52017 Pig CETN2 antibody; Sus scrofa CETN2 antibody F2Z563 86.0%
ARP60115 Rainbow smelt CETN2 antibody; Osmerus mordax CETN2 antibody C1BM03 83.0%
ARP60115 Rat CETN2 antibody; Rattus norvegicus CETN2 antibody Q99MJ7 100.0%
ARP60115 Rat CETN2 antibody; Rattus norvegicus CETN2 antibody G3V9W0 100.0%
ARP52017 Rat CETN2 antibody; Rattus norvegicus CETN2 antibody G3V9W0 86.0%
ARP52038 Red flour beetle CETN2 antibody; Tribolium castaneum CETN2 antibody D2A0V1 79.0%
ARP60115 Rhesus macaque CETN2 antibody; Macaca mulatta CETN2 antibody F7HKU5 100.0%
ARP60115 Rhesus macaque CETN2 antibody; Macaca mulatta CETN2 antibody F7HT47 100.0%
ARP52017 Rhesus macaque CETN2 antibody; Macaca mulatta CETN2 antibody F7HKU5 86.0%
ARP52017 Rhesus macaque CETN2 antibody; Macaca mulatta CETN2 antibody F7HT47 86.0%
ARP60115 Sheep CETN2 antibody; Ovis aries CETN2 antibody C7BDV8 100.0%
ARP52017 Sheep CETN2 antibody; Ovis aries CETN2 antibody C7BDV8 86.0%
ARP60115 Sumatran orangutan CETN2 antibody; Pongo abelii CETN2 antibody H2PX40 100.0%
ARP52017 Sumatran orangutan CETN2 antibody; Pongo abelii CETN2 antibody H2PX40 86.0%
ARP60115 Thirteen-lined ground squirrel CETN2 antibody; Spermophilus tridecemlineatus CETN2 antibody I3N8D8 100.0%
ARP52017 Thirteen-lined ground squirrel CETN2 antibody; Spermophilus tridecemlineatus CETN2 antibody I3N8D8 86.0%
ARP60115 Zebrafish CETN2 antibody; Danio rerio CETN2 antibody E7F903 86.0%
ARP52017 Zebrafish CETN2 antibody; Danio rerio CETN2 antibody E7F903 85.0%
ARP52018 Zebrafish CETN2 antibody; Danio rerio CETN2 antibody E7F903 83.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas209194_at721_B_lymphoblasts40.95039.280Details
BioGPS Gene Atlas209194_atAdipocyte70.20039.280Details
BioGPS Gene Atlas209194_atAdrenalCortex14.70039.280Details
BioGPS Gene Atlas209194_atAdrenalgland18.10039.280Details
BioGPS Gene Atlas209194_atAmygdala64.00039.280Details
BioGPS Gene Atlas209194_atAppendix18.00039.280Details
BioGPS Gene Atlas209194_atAtrioventricularNode8.15039.280Details
BioGPS Gene Atlas209194_atBDCA4+_DentriticCells31.75039.280Details
BioGPS Gene Atlas209194_atBonemarrow12.75039.280Details
BioGPS Gene Atlas209194_atBronchialEpithelialCells105.75039.280Details
BioGPS Gene Atlas209194_atCD105+_Endothelial26.10039.280Details
BioGPS Gene Atlas209194_atCD14+_Monocytes23.80039.280Details
BioGPS Gene Atlas209194_atCD19+_BCells(neg._sel.)23.65039.280Details
BioGPS Gene Atlas209194_atCD33+_Myeloid17.70039.280Details
BioGPS Gene Atlas209194_atCD34+39.05039.280Details
BioGPS Gene Atlas209194_atCD4+_Tcells11.90039.280Details
BioGPS Gene Atlas209194_atCD56+_NKCells69.10039.280Details
BioGPS Gene Atlas209194_atCD71+_EarlyErythroid24.80039.280Details
BioGPS Gene Atlas209194_atCD8+_Tcells13.55039.280Details
BioGPS Gene Atlas209194_atCardiacMyocytes32.30039.280Details
BioGPS Gene Atlas209194_atCaudatenucleus54.40039.280Details
BioGPS Gene Atlas209194_atCerebellum7.25039.280Details
BioGPS Gene Atlas209194_atCerebellumPeduncles12.45039.280Details
BioGPS Gene Atlas209194_atCiliaryGanglion10.55039.280Details
BioGPS Gene Atlas209194_atCingulateCortex26.85039.280Details
BioGPS Gene Atlas209194_atColorectaladenocarcinoma19.75039.280Details
BioGPS Gene Atlas209194_atDorsalRootGanglion9.50039.280Details
BioGPS Gene Atlas209194_atFetalThyroid38.15039.280Details
BioGPS Gene Atlas209194_atFetalbrain38.50039.280Details
BioGPS Gene Atlas209194_atFetalliver41.85039.280Details
BioGPS Gene Atlas209194_atFetallung116.00039.280Details
BioGPS Gene Atlas209194_atGlobusPallidus15.00039.280Details
BioGPS Gene Atlas209194_atHeart11.75039.280Details
BioGPS Gene Atlas209194_atHypothalamus153.60039.280Details
BioGPS Gene Atlas209194_atKidney24.30039.280Details
BioGPS Gene Atlas209194_atLeukemia_chronicMyelogenousK-56213.95039.280Details
BioGPS Gene Atlas209194_atLeukemia_promyelocytic-HL-6017.35039.280Details
BioGPS Gene Atlas209194_atLeukemialymphoblastic(MOLT-4)14.60039.280Details
BioGPS Gene Atlas209194_atLiver14.80039.280Details
BioGPS Gene Atlas209194_atLung17.60039.280Details
BioGPS Gene Atlas209194_atLymphnode11.85039.280Details
BioGPS Gene Atlas209194_atLymphoma_burkitts(Daudi)16.60039.280Details
BioGPS Gene Atlas209194_atLymphoma_burkitts(Raji)12.90039.280Details
BioGPS Gene Atlas209194_atMedullaOblongata21.85039.280Details
BioGPS Gene Atlas209194_atOccipitalLobe24.80039.280Details
BioGPS Gene Atlas209194_atOlfactoryBulb26.80039.280Details
BioGPS Gene Atlas209194_atOvary12.35039.280Details
BioGPS Gene Atlas209194_atPancreas16.80039.280Details
BioGPS Gene Atlas209194_atPancreaticIslet60.00039.280Details
BioGPS Gene Atlas209194_atParietalLobe21.75039.280Details
BioGPS Gene Atlas209194_atPituitary135.35039.280Details
BioGPS Gene Atlas209194_atPlacenta13.65039.280Details
BioGPS Gene Atlas209194_atPons22.85039.280Details
BioGPS Gene Atlas209194_atPrefrontalCortex53.75039.280Details
BioGPS Gene Atlas209194_atProstate29.15039.280Details
BioGPS Gene Atlas209194_atSalivarygland14.50039.280Details
BioGPS Gene Atlas209194_atSkeletalMuscle15.75039.280Details
BioGPS Gene Atlas209194_atSkin6.70039.280Details
BioGPS Gene Atlas209194_atSmoothMuscle96.85039.280Details
BioGPS Gene Atlas209194_atSpinalcord37.60039.280Details
BioGPS Gene Atlas209194_atSubthalamicNucleus19.15039.280Details
BioGPS Gene Atlas209194_atSuperiorCervicalGanglion23.60039.280Details
BioGPS Gene Atlas209194_atTemporalLobe21.90039.280Details
BioGPS Gene Atlas209194_atTestis16.75039.280Details
BioGPS Gene Atlas209194_atTestisGermCell26.20039.280Details
BioGPS Gene Atlas209194_atTestisIntersitial13.05039.280Details
BioGPS Gene Atlas209194_atTestisLeydigCell19.15039.280Details
BioGPS Gene Atlas209194_atTestisSeminiferousTubule15.80039.280Details
BioGPS Gene Atlas209194_atThalamus50.65039.280Details
BioGPS Gene Atlas209194_atThymus13.25039.280Details
BioGPS Gene Atlas209194_atThyroid141.60039.280Details
BioGPS Gene Atlas209194_atTongue13.05039.280Details
BioGPS Gene Atlas209194_atTonsil13.90039.280Details
BioGPS Gene Atlas209194_atTrachea74.25039.280Details
BioGPS Gene Atlas209194_atTrigeminalGanglion18.80039.280Details
BioGPS Gene Atlas209194_atUterus54.05039.280Details
BioGPS Gene Atlas209194_atUterusCorpus22.45039.280Details
BioGPS Gene Atlas209194_atWholeBlood17.40039.280Details
BioGPS Gene Atlas209194_atWholebrain22.90039.280Details
BioGPS Gene Atlas209194_atcolon34.90039.280Details
BioGPS Gene Atlas209194_atpineal_day128.66039.280Details
BioGPS Gene Atlas209194_atpineal_night137.44039.280Details
BioGPS Gene Atlas209194_atretina80.45039.280Details
BioGPS Gene Atlas209194_atsmall_intestine20.95039.280Details
BioGPS NCI60209194_at786461.581655.960Details
BioGPS NCI60209194_atA1722014.127655.960Details
BioGPS NCI60209194_atA204242.933655.960Details
BioGPS NCI60209194_atA361428.679655.960Details
BioGPS NCI60209194_atA498618.583655.960Details
BioGPS NCI60209194_atA5491055.428655.960Details
BioGPS NCI60209194_atACC3593.100655.960Details
BioGPS NCI60209194_atACHN763.745655.960Details
BioGPS NCI60209194_atALVA31976.427655.960Details
BioGPS NCI60209194_atCAKI1625.873655.960Details
BioGPS NCI60209194_atCCRT CEM64.855655.960Details
BioGPS NCI60209194_atCOLO205749.645655.960Details
BioGPS NCI60209194_atDLD1500.043655.960Details
BioGPS NCI60209194_atDU145297.840655.960Details
BioGPS NCI60209194_atEKVX1532.069655.960Details
BioGPS NCI60209194_atGM1331107.517655.960Details
BioGPS NCI60209194_atGM1600554.997655.960Details
BioGPS NCI60209194_atGM2313595.713655.960Details
BioGPS NCI60209194_atGM2345512.903655.960Details
BioGPS NCI60209194_atGM24931048.459655.960Details
BioGPS NCI60209194_atGM97313.985655.960Details
BioGPS NCI60209194_atHCC2998173.820655.960Details
BioGPS NCI60209194_atHCT116338.830655.960Details
BioGPS NCI60209194_atHCT15702.482655.960Details
BioGPS NCI60209194_atHEK 293 T-rex269.849655.960Details
BioGPS NCI60209194_atHEK 293T996.276655.960Details
BioGPS NCI60209194_atHEK293413.041655.960Details
BioGPS NCI60209194_atHELA718.145655.960Details
BioGPS NCI60209194_atHEPG2729.200655.960Details
BioGPS NCI60209194_atHL6080.189655.960Details
BioGPS NCI60209194_atHOP621366.539655.960Details
BioGPS NCI60209194_atHOP921184.565655.960Details
BioGPS NCI60209194_atHS578T824.661655.960Details
BioGPS NCI60209194_atHSG612.336655.960Details
BioGPS NCI60209194_atHT1080249.396655.960Details
BioGPS NCI60209194_atHT29903.841655.960Details
BioGPS NCI60209194_atIGROV1864.964655.960Details
BioGPS NCI60209194_atIOSE80882.488655.960Details
BioGPS NCI60209194_atJURKAT280.120655.960Details
BioGPS NCI60209194_atK562142.322655.960Details
BioGPS NCI60209194_atKM1286.814655.960Details
BioGPS NCI60209194_atLN18411.858655.960Details
BioGPS NCI60209194_atLNCAP836.350655.960Details
BioGPS NCI60209194_atLOX IMVI390.896655.960Details
BioGPS NCI60209194_atM14536.761655.960Details
BioGPS NCI60209194_atMALME 3M57.890655.960Details
BioGPS NCI60209194_atMCF71584.052655.960Details
BioGPS NCI60209194_atMD MB231181.830655.960Details
BioGPS NCI60209194_atMDA MB435305.589655.960Details
BioGPS NCI60209194_atMOLT4320.569655.960Details
BioGPS NCI60209194_atNCI 460428.097655.960Details
BioGPS NCI60209194_atNCI H226559.171655.960Details
BioGPS NCI60209194_atNCI H231081.469655.960Details
BioGPS NCI60209194_atNCI H322M336.755655.960Details
BioGPS NCI60209194_atNCVADR RES266.301655.960Details
BioGPS NCI60209194_atOVCAR3413.078655.960Details
BioGPS NCI60209194_atOVCAR41194.503655.960Details
BioGPS NCI60209194_atOVCAR5205.130655.960Details
BioGPS NCI60209194_atOVCAR8512.350655.960Details
BioGPS NCI60209194_atPANC11197.678655.960Details
BioGPS NCI60209194_atRL7157.075655.960Details
BioGPS NCI60209194_atRPMI 8226544.660655.960Details
BioGPS NCI60209194_atRS1184633.910655.960Details
BioGPS NCI60209194_atRXF393490.410655.960Details
BioGPS NCI60209194_atSAOS2371.782655.960Details
BioGPS NCI60209194_atSF268713.805655.960Details
BioGPS NCI60209194_atSF295596.087655.960Details
BioGPS NCI60209194_atSF539749.670655.960Details
BioGPS NCI60209194_atSHSYSY+RA177.507655.960Details
BioGPS NCI60209194_atSHSYSY-RA332.959655.960Details
BioGPS NCI60209194_atSKMEL2488.314655.960Details
BioGPS NCI60209194_atSKMEL28146.826655.960Details
BioGPS NCI60209194_atSKMEL5297.514655.960Details
BioGPS NCI60209194_atSKOV3940.267655.960Details
BioGPS NCI60209194_atSN12C1663.417655.960Details
BioGPS NCI60209194_atSNB191391.685655.960Details
BioGPS NCI60209194_atSNB75958.912655.960Details
BioGPS NCI60209194_atSR148.063655.960Details
BioGPS NCI60209194_atSW620424.957655.960Details
BioGPS NCI60209194_atT241648.379655.960Details
BioGPS NCI60209194_atT3M4148.195655.960Details
BioGPS NCI60209194_atTK10272.982655.960Details
BioGPS NCI60209194_atU1181601.799655.960Details
BioGPS NCI60209194_atU1381157.037655.960Details
BioGPS NCI60209194_atU20S447.799655.960Details
BioGPS NCI60209194_atU251571.848655.960Details
BioGPS NCI60209194_atU872177.709655.960Details
BioGPS NCI60209194_atUACC257207.792655.960Details
BioGPS NCI60209194_atUACC62440.668655.960Details
BioGPS NCI60209194_atUO31598.554655.960Details
BioGPS NCI60209194_atZR75_1214.863655.960Details
BioGPS NCI60209194_atastrocytes388.925655.960Details
BioGPS NCI60209194_athuh-7351.046655.960Details