Search Antibody, Protein, and ELISA Kit Solutions


Gene ID: 204219 | CERS3 Antibody Resource


CERS3 Antibody Resource
Gene Full Name: 
ceramide synthase 3
Uniprot: 
Q8IU89
Protein Name: 
ceramide synthase 3
Nucleotide: 
NM_178842
Alias: 
ARCI9;LASS3;
Ensembl: 
ENSG00000154227
Location: 
15q26.3
HPRD: 
13961
NCBI Gene: 
204219
MIM: 
615276

Summary: 
Function: 
Has (dihydro)ceramide synthesis activity with relatively broad substrate specificity, but a preference for C18:0 and other middle- to long-chain fatty acyl-CoAs . It is crucial for the synthesis of very long-chain ceramides in the epidermis, to maintain epidermal lipid homeostasis and terminal differentiation.
Subcellular location: 
Nucleus membrane; Multi-pass membrane protein Potential.
PTM: 
Disease: 
Ichthyosis, congenital, autosomal recessive 9 (ARCI9) [MIM:615023]: A form of autosomal recessive congenital ichthyosis, a disorder of keratinization with abnormal differentiation and desquamation of the epidermis, resulting in abnormal skin scaling over the whole body. The main skin phenotypes are lamellar ichthyosis (LI) and non-bullous congenital ichthyosiform erythroderma (NCIE), although phenotypic overlap within the same patient or among patients from the same family can occur. Lamellar ichthyosis is a condition often associated with an embedment in a collodion-like membrane at birth; skin scales later develop, covering the entire body surface. Non-bullous congenital ichthyosiform erythroderma characterized by fine whitish scaling on an erythrodermal background; larger brownish scales are present on the buttocks, neck and legs. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP31648_P050 LASS3 antibody - N-terminal region (ARP31648_P050) Polyclonal Dog, Mouse, Pig WB 50ug $289 Details
Polyclonal Antibody ARP32255_P050 CERS3 Antibody (ARP32255_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $50 Details

Show all CERS3 antibodies


Product Images
LASS3 antibody - N-terminal region (ARP31648_P050) in Human Liver cells using Western Blot

Sample Type: Human Liver


CERS3 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP32255 Cat CERS3 antibody; Felis catus CERS3 antibody M3W7W4 100.0%
ARP31648 Cat CERS3 antibody; Felis catus CERS3 antibody M3W7W4 85.0%
ARP31648 Chimpanzee CERS3 antibody; Pan troglodytes CERS3 antibody H2RD09 100.0%
ARP32255 Chimpanzee CERS3 antibody; Pan troglodytes CERS3 antibody H2RD09 100.0%
ARP32255 Chinese softshell turtle CERS3 antibody; Pelodiscus sinensis CERS3 antibody K7G8P4 83.0%
ARP32255 Dog CERS3 antibody; Canis familiaris CERS3 antibody F6XW58 100.0%
ARP31648 Dog CERS3 antibody; Canis familiaris CERS3 antibody F6XW58 93.0%
ARP32255 Duckbill platypus CERS3 antibody; Ornithorhynchus anatinus CERS3 antibody F6W2Y9 100.0%
ARP31648 European domestic ferret CERS3 antibody; Mustela putorius furo CERS3 antibody M3YHK1 100.0%
ARP32255 European domestic ferret CERS3 antibody; Mustela putorius furo CERS3 antibody M3YHK1 100.0%
ARP31648 Giant panda CERS3 antibody; Ailuropoda melanoleuca CERS3 antibody G1M7E0 100.0%
ARP32255 Giant panda CERS3 antibody; Ailuropoda melanoleuca CERS3 antibody G1M7E0 100.0%
ARP32255 Gray short-tailed opossum CERS3 antibody; Monodelphis domestica CERS3 antibody F7CYJ2 100.0%
ARP32255 Horse CERS3 antibody; Equus caballus CERS3 antibody F6PUZ6 92.0%
ARP31648 Horse CERS3 antibody; Equus caballus CERS3 antibody F6PUZ6 85.0%
ARP31648 Human CERS3 antibody; Homo sapiens CERS3 antibody Q8IU89 100.0%
ARP32255 Human CERS3 antibody; Homo sapiens CERS3 antibody Q8IU89 100.0%
ARP31648 Human CERS3 antibody; Homo sapiens CERS3 antibody H0YN05 100.0%
ARP32255 Human CERS3 antibody; Homo sapiens CERS3 antibody H0YN05 100.0%
ARP32255 Mouse CERS3 antibody; Mus musculus CERS3 antibody Q1A3B0-2 100.0%
ARP32255 Mouse CERS3 antibody; Mus musculus CERS3 antibody Q1A3B0 100.0%
ARP31648 Mouse CERS3 antibody; Mus musculus CERS3 antibody Q1A3B0-2 85.0%
ARP31648 Mouse CERS3 antibody; Mus musculus CERS3 antibody Q1A3B0 85.0%
ARP32255 Pig CERS3 antibody; Sus scrofa CERS3 antibody F1SR96 92.0%
ARP31648 Pig CERS3 antibody; Sus scrofa CERS3 antibody F1SR96 79.0%
ARP62942 Rabbit CERS3 antibody; Oryctolagus cuniculus CERS3 antibody G1SKI0 82.0%
ARP32255 Rat CERS3 antibody; Rattus norvegicus CERS3 antibody B1H294 92.0%
ARP31648 Small-eared galago CERS3 antibody; Otolemur garnettii CERS3 antibody H0WXL2 100.0%
ARP32255 Small-eared galago CERS3 antibody; Otolemur garnettii CERS3 antibody H0WXL2 100.0%
ARP31648 Sumatran orangutan CERS3 antibody; Pongo abelii CERS3 antibody H2NPB6 100.0%
ARP32255 Sumatran orangutan CERS3 antibody; Pongo abelii CERS3 antibody H2NPB6 100.0%
ARP32255 Tasmanian devil CERS3 antibody; Sarcophilus harrisii CERS3 antibody G3VHI1 100.0%
ARP32255 Tasmanian devil CERS3 antibody; Sarcophilus harrisii CERS3 antibody G3VHI2 100.0%
ARP32255 Thirteen-lined ground squirrel CERS3 antibody; Spermophilus tridecemlineatus CERS3 antibody I3M4F7 100.0%
ARP31648 Thirteen-lined ground squirrel CERS3 antibody; Spermophilus tridecemlineatus CERS3 antibody I3M4F7 93.0%
ARP32255 White-tufted-ear marmoset CERS3 antibody; Callithrix jacchus CERS3 antibody F7I7W6 100.0%
ARP31648 White-tufted-ear marmoset CERS3 antibody; Callithrix jacchus CERS3 antibody F7I7W6 93.0%

Tissue & Cell Line Gene Expression Data