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Gene ID: 387103 | CENPW Antibody Resource


CENPW Antibody Resource
Gene Full Name: 
centromere protein W
Uniprot: 
Q5EE01
Protein Name: 
centromere protein W
Nucleotide: 
XM_005266966
Alias: 
CUG2;CENP-W;C6orf173;
Ensembl: 
ENSG00000203760
Location: 
6q22.32
HPRD: 
16660
NCBI Gene: 
387103
MIM: 
611264

Summary: 
Function: 
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation . The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres . Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPW has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis.
Subcellular location: 
Nucleus. Chromosome › centromere. Chromosome › centromere › kinetochore. Nucleus matrix. Nucleus › nucleolus. Note: Constitutively localizes to centromeres throughout the cell cycle, and to the inner kinetochore during mitosis.
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP54417_P050 C6orf173 antibody - N-terminal region (ARP54417_P050) Polyclonal Human WB 50ug $289 Details
Polyclonal Antibody ARP54418_P050 CENPW Antibody (ARP54418_P050) Polyclonal Bovine, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details

Show all CENPW antibodies


Product Images
C6orf173 antibody - N-terminal region (ARP54417_P050) in Human HeLa cells using Western Blot

Sample Type: Human HeLa


CENPW Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP54417 Cat CENPW antibody; Felis catus CENPW antibody M3XEA8 79.0%
ARP54418 Cat CENPW antibody; Felis catus CENPW antibody M3XEA8 79.0%
ARP54418 Chicken CENPW antibody; Gallus gallus CENPW antibody P0DJH6 86.0%
ARP54418 Chicken CENPW antibody; Gallus gallus CENPW antibody R4GIZ7 86.0%
ARP54418 Chicken CENPW antibody; Gallus gallus CENPW antibody H9KVH8 86.0%
ARP54417 Chimpanzee CENPW antibody; Pan troglodytes CENPW antibody H2R6Y9 100.0%
ARP54418 Chimpanzee CENPW antibody; Pan troglodytes CENPW antibody H2R6Y9 100.0%
ARP54417 Chimpanzee CENPW antibody; Pan troglodytes CENPW antibody K7C893 100.0%
ARP54418 Chimpanzee CENPW antibody; Pan troglodytes CENPW antibody K7C893 100.0%
ARP54418 Collared flycatcher CENPW antibody; Ficedula albicollis CENPW antibody U3KAE8 86.0%
ARP54418 Dog CENPW antibody; Canis familiaris CENPW antibody J9P4X1 93.0%
ARP54418 Domestic duck CENPW antibody; Anas platyrhynchos CENPW antibody U3I2Y3 79.0%
ARP54418 Giant panda CENPW antibody; Ailuropoda melanoleuca CENPW antibody G1LSC9 86.0%
ARP54417 Giant panda CENPW antibody; Ailuropoda melanoleuca CENPW antibody G1LSC9 79.0%
ARP54418 Horse CENPW antibody; Equus caballus CENPW antibody F7BYX5 100.0%
ARP54417 Horse CENPW antibody; Equus caballus CENPW antibody F7BYX5 79.0%
ARP54417 Human CENPW antibody; Homo sapiens CENPW antibody Q5EE01 100.0%
ARP54418 Human CENPW antibody; Homo sapiens CENPW antibody Q5EE01 100.0%
ARP54418 Mouse CENPW antibody; Mus musculus CENPW antibody Q3URR0 86.0%
ARP54418 Mouse CENPW antibody; Mus musculus CENPW antibody B2RVH1 86.0%
ARP54418 Pig CENPW antibody; Sus scrofa CENPW antibody F1S2W8 93.0%
ARP54418 Rabbit CENPW antibody; Oryctolagus cuniculus CENPW antibody G1TMQ2 100.0%
ARP54418 Rat CENPW antibody; Rattus norvegicus CENPW antibody A1L1L1 86.0%
ARP54418 Rhesus macaque CENPW antibody; Macaca mulatta CENPW antibody F7GUD7 100.0%
ARP54417 Rhesus macaque CENPW antibody; Macaca mulatta CENPW antibody F7GUD7 93.0%
ARP54418 Small-eared galago CENPW antibody; Otolemur garnettii CENPW antibody H0XS85 100.0%
ARP54417 Small-eared galago CENPW antibody; Otolemur garnettii CENPW antibody H0XS85 86.0%
ARP54417 Sumatran orangutan CENPW antibody; Pongo abelii CENPW antibody H2PKA0 100.0%
ARP54418 Sumatran orangutan CENPW antibody; Pongo abelii CENPW antibody H2PKA0 100.0%
ARP54418 Tasmanian devil CENPW antibody; Sarcophilus harrisii CENPW antibody G3WYY5 91.0%
ARP54418 Thirteen-lined ground squirrel CENPW antibody; Spermophilus tridecemlineatus CENPW antibody I3MWD2 93.0%
ARP54418 White-tufted-ear marmoset CENPW antibody; Callithrix jacchus CENPW antibody F7GQF0 100.0%
ARP54417 White-tufted-ear marmoset CENPW antibody; Callithrix jacchus CENPW antibody F7GQF0 86.0%
ARP54418 Zebra finch CENPW antibody; Taeniopygia guttata CENPW antibody H1A544 86.0%
ARP54418 Zebra finch CENPW antibody; Taeniopygia guttata CENPW antibody H1A5W2 86.0%

Tissue & Cell Line Gene Expression Data