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Gene ID: 64946 | CENPH Antibody Resource


CENPH Antibody Resource
Gene Full Name: 
centromere protein H
Uniprot: 
Q9H3R5
Protein Name: 
centromere protein H
Nucleotide: 
NM_022909
Alias: 
Ensembl: 
ENSG00000153044
Location: 
5p15.2
HPRD: 
12029
NCBI Gene: 
64946
MIM: 
605607

Summary: 
Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex. [provided by RefSeq, Jul 2008]
Function: 
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.
Subcellular location: 
Nucleus. Chromosome › centromere › kinetochore. Note: Associates with active centromere-kinetochore complexes throughout the cell cycle. Colocalizes with inner kinetochore plate proteins CENPA and CENPC during both interphase and metaphase.
PTM: 
Acetylation;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP58266_P050 CENPH antibody - middle region (ARP58266_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse WB 50ug $289 Details
Polyclonal Antibody ARP58265_P050 CENPH antibody - N-terminal region (ARP58265_P050) Polyclonal Human WB 50ug $289 Details
Polyclonal Antibody OAAB05804 CENPH antibody - center region (OAAB05804) Human WB, FC, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP58267_P050 CENPH Antibody (ARP58267_P050) Polyclonal Bovine, Dog, Horse, Human, Rat Not tested 50 ug $125 Details

Show all CENPH antibodies


Product Images
CENPH antibody - N-terminal region (ARP58265_P050) in Human Spleen cells using Western Blot

Sample Type: Human Spleen

CENPH antibody - middle region (ARP58266_P050) in Human Liver cells using Western Blot

Sample Type: Human Liver

CENPH antibody - center region (OAAB05804) in Hela cells using Western Blot

Sample Type: Hela

CENPH antibody - center region (OAAB05804) in Hela cells using Flow Cytometry

Sample Type: Hela

CENPH antibody - center region (OAAB05804) in Human Testis cells using Immunohistochemistry

Sample Type: Human Testis


CENPH Protocols

Publications
Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP58266 Bovine CENPH antibody; Bos taurus CENPH antibody Q3T0L1 93.0%
ARP58267 Bovine CENPH antibody; Bos taurus CENPH antibody Q3T0L1 93.0%
ARP58266 Cat CENPH antibody; Felis catus CENPH antibody M3X519 100.0%
ARP58267 Cat CENPH antibody; Felis catus CENPH antibody M3X519 92.0%
ARP58265 Chimpanzee CENPH antibody; Pan troglodytes CENPH antibody H2QR06 100.0%
ARP58266 Chimpanzee CENPH antibody; Pan troglodytes CENPH antibody H2QR06 100.0%
ARP58267 Chimpanzee CENPH antibody; Pan troglodytes CENPH antibody H2QR06 93.0%
ARP58267 Dog CENPH antibody; Canis familiaris CENPH antibody E2R8X4 92.0%
ARP58267 Dog CENPH antibody; Canis familiaris CENPH antibody J9P5K5 92.0%
ARP58266 Dog CENPH antibody; Canis familiaris CENPH antibody E2R8X4 79.0%
ARP58266 Dog CENPH antibody; Canis familiaris CENPH antibody J9P5K5 79.0%
ARP58266 European domestic ferret CENPH antibody; Mustela putorius furo CENPH antibody M3YT77 100.0%
ARP58267 European domestic ferret CENPH antibody; Mustela putorius furo CENPH antibody M3YT77 92.0%
ARP58266 Giant panda CENPH antibody; Ailuropoda melanoleuca CENPH antibody G1L8V0 100.0%
ARP58267 Giant panda CENPH antibody; Ailuropoda melanoleuca CENPH antibody G1L8V0 92.0%
ARP58266 Guinea pig CENPH antibody; Cavia porcellus CENPH antibody H0W563 93.0%
ARP58266 Horse CENPH antibody; Equus caballus CENPH antibody F6PLT4 100.0%
ARP58267 Horse CENPH antibody; Equus caballus CENPH antibody F6PLT4 93.0%
ARP58266 Human CENPH antibody; Homo sapiens CENPH antibody H0Y9E6 100.0%
ARP58267 Human CENPH antibody; Homo sapiens CENPH antibody H0Y9E6 100.0%
ARP58265 Human CENPH antibody; Homo sapiens CENPH antibody B3KVZ3 100.0%
ARP58266 Human CENPH antibody; Homo sapiens CENPH antibody B3KVZ3 100.0%
ARP58267 Human CENPH antibody; Homo sapiens CENPH antibody B3KVZ3 100.0%
ARP58265 Human CENPH antibody; Homo sapiens CENPH antibody D6RBJ6 100.0%
ARP58265 Human CENPH antibody; Homo sapiens CENPH antibody Q9H3R5 100.0%
ARP58266 Human CENPH antibody; Homo sapiens CENPH antibody Q9H3R5 100.0%
ARP58267 Human CENPH antibody; Homo sapiens CENPH antibody Q9H3R5 100.0%
ARP58266 Mouse CENPH antibody; Mus musculus CENPH antibody Q9QYM8 93.0%
ARP58266 Pig CENPH antibody; Sus scrofa CENPH antibody I3LPJ0 100.0%
ARP58265 Pig CENPH antibody; Sus scrofa CENPH antibody I3LPJ0 86.0%
ARP58267 Rabbit CENPH antibody; Oryctolagus cuniculus CENPH antibody U3KP60 93.0%
ARP58266 Rabbit CENPH antibody; Oryctolagus cuniculus CENPH antibody U3KP60 86.0%
ARP58266 Rat CENPH antibody; Rattus norvegicus CENPH antibody F1M389 93.0%
ARP58266 Rat CENPH antibody; Rattus norvegicus CENPH antibody M0R9L1 93.0%
ARP58266 Rhesus macaque CENPH antibody; Macaca mulatta CENPH antibody F7GYV6 100.0%
ARP58267 Rhesus macaque CENPH antibody; Macaca mulatta CENPH antibody F7GYV6 100.0%
ARP58265 Rhesus macaque CENPH antibody; Macaca mulatta CENPH antibody F7GYV6 85.0%
ARP58266 Small-eared galago CENPH antibody; Otolemur garnettii CENPH antibody H0WK59 93.0%
ARP58267 Small-eared galago CENPH antibody; Otolemur garnettii CENPH antibody H0WK59 79.0%
ARP58266 Sumatran orangutan CENPH antibody; Pongo abelii CENPH antibody H2PFR2 100.0%
ARP58267 Sumatran orangutan CENPH antibody; Pongo abelii CENPH antibody H2PFR2 100.0%
ARP58265 Sumatran orangutan CENPH antibody; Pongo abelii CENPH antibody H2PFR2 93.0%
ARP58266 White-tufted-ear marmoset CENPH antibody; Callithrix jacchus CENPH antibody F7HY65 100.0%
ARP58267 White-tufted-ear marmoset CENPH antibody; Callithrix jacchus CENPH antibody F7HY65 100.0%
ARP58266 White-tufted-ear marmoset CENPH antibody; Callithrix jacchus CENPH antibody F7HY66 100.0%
ARP58267 White-tufted-ear marmoset CENPH antibody; Callithrix jacchus CENPH antibody F7HY66 100.0%
ARP58266 White-tufted-ear marmoset CENPH antibody; Callithrix jacchus CENPH antibody F7IJ38 100.0%
ARP58267 White-tufted-ear marmoset CENPH antibody; Callithrix jacchus CENPH antibody F7IJ38 100.0%
ARP58265 White-tufted-ear marmoset CENPH antibody; Callithrix jacchus CENPH antibody F7HY65 85.0%
ARP58265 White-tufted-ear marmoset CENPH antibody; Callithrix jacchus CENPH antibody F7HY66 85.0%
ARP58265 White-tufted-ear marmoset CENPH antibody; Callithrix jacchus CENPH antibody F7IJ38 85.0%

Tissue & Cell Line Gene Expression Data