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Gene ID: 1062 | CENPE Antibody Resource


CENPE Antibody Resource
Gene Full Name: 
centromere protein E, 312kDa
Uniprot: 
Q02224
Protein Name: 
centromere-associated protein E
Nucleotide: 
NM_001813
Alias: 
KIF10;CENP-E;PPP1R61;
Ensembl: 
ENSG00000138778
Location: 
4q24-q25
HPRD: 
00316
NCBI Gene: 
1062
MIM: 
117143

Summary: 
Centrosome-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation. [provided by RefSeq, Jul 2008]
Function: 
Essential for the maintenance of chromosomal stability through efficient stabilization of microtubule capture at kinetochores. Plays a key role in the movement of chromosomes toward the metaphase plate during mitosis. Is a slow plus end-directed motor whose activity is essential for metaphase chromosome alignment. Couples chromosome position to microtubule depolymerizing activity. The highly processive microtubule-dependent motor activity of CENPE serves to power chromosome congression and provides a flexible, motile tether linking kinetochores to dynamic spindle microtubules. Necessary for the mitotic checkpoint signal at individual kinetochores to prevent aneuploidy due to single chromosome loss. Required for the efficient recruitment of BUBR1, MAD1 and MAD2 to attached and newly unattached kinetochores. Stimulates mammalian BUBR1 kinase activity. Accumulates just before mitosis at the G2 phase of the cell cycle.
Subcellular location: 
Chromosome › centromere › kinetochore. Cytoplasm › cytoskeleton › spindle. Note: Associates with kinetochores during congression (as early as prometaphase), relocates to the spindle midzone at anaphase, and is quantitatively discarded at the end of the cell division.
PTM: 
Isopeptide bond;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAEB00379 CENPE Antibody (OAEB00379) Bovine, Dog, Human ELISA 0.1mg $229 Details
Polyclonal Antibody ARP33895_P050 CENPE Antibody (ARP33895_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Pig, Rabbit Not tested 50 ug $50 Details
Polyclonal Antibody ARP33896_P050 CENPE Antibody (ARP33896_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Pig, Rabbit Not tested 50 ug $50 Details
Polyclonal Antibody ARP34031_P050 CENPE Antibody (ARP34031_P050) Polyclonal Human, Rabbit Not tested 50 ug $125 Details
Polyclonal Antibody OAAB13414 CENPE antibody - C - terminal region (OAAB13414) Human WB 400ul $289 Details

Show all CENPE antibodies


Product Images
CENPE antibody - C - terminal region (OAAB13414) in Hela cells using Western Blot

Sample Type: Hela


CENPE Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP33895 Bovine CENPE antibody; Bos taurus CENPE antibody G3N251 86.0%
ARP33895 Bovine CENPE antibody; Bos taurus CENPE antibody E1BG49 86.0%
ARP33895 Bovine CENPE antibody; Bos taurus CENPE antibody G3MZG5 86.0%
ARP33896 Bovine CENPE antibody; Bos taurus CENPE antibody G3N251 79.0%
ARP33896 Bovine CENPE antibody; Bos taurus CENPE antibody E1BG49 79.0%
ARP33896 Bovine CENPE antibody; Bos taurus CENPE antibody G3MZG5 79.0%
ARP33896 Cat CENPE antibody; Felis catus CENPE antibody M3W0I0 93.0%
ARP33895 Cat CENPE antibody; Felis catus CENPE antibody M3W0I0 86.0%
ARP34031 Cat CENPE antibody; Felis catus CENPE antibody M3W0I0 86.0%
ARP70050 Cat CENPE antibody; Felis catus CENPE antibody M3W0I0 80.0%
ARP33895 Chimpanzee CENPE antibody; Pan troglodytes CENPE antibody H2QPZ3 100.0%
ARP33896 Chimpanzee CENPE antibody; Pan troglodytes CENPE antibody H2QPZ3 100.0%
ARP34031 Chimpanzee CENPE antibody; Pan troglodytes CENPE antibody H2QPZ3 100.0%
ARP33896 Dog CENPE antibody; Canis familiaris CENPE antibody E2R200 100.0%
ARP33896 Dog CENPE antibody; Canis familiaris CENPE antibody J9JHU7 100.0%
ARP33895 Dog CENPE antibody; Canis familiaris CENPE antibody E2R200 86.0%
ARP33895 Dog CENPE antibody; Canis familiaris CENPE antibody J9JHU7 86.0%
ARP33896 European domestic ferret CENPE antibody; Mustela putorius furo CENPE antibody M3YCQ7 93.0%
ARP33895 European domestic ferret CENPE antibody; Mustela putorius furo CENPE antibody M3YCQ7 86.0%
ARP33895 Horse CENPE antibody; Equus caballus CENPE antibody F6S685 79.0%
ARP34031 Human CENPE antibody; Homo sapiens CENPE antibody Q02224-3 100.0%
ARP33895 Human CENPE antibody; Homo sapiens CENPE antibody Q02224 100.0%
ARP33896 Human CENPE antibody; Homo sapiens CENPE antibody Q02224 100.0%
ARP34031 Human CENPE antibody; Homo sapiens CENPE antibody Q02224 100.0%
ARP33895 Human CENPE antibody; Homo sapiens CENPE antibody D6RBW0 100.0%
ARP34031 Human CENPE antibody; Homo sapiens CENPE antibody D6RBW0 100.0%
ARP33895 Human CENPE antibody; Homo sapiens CENPE antibody Q02224-2 100.0%
ARP33896 Human CENPE antibody; Homo sapiens CENPE antibody Q02224-2 100.0%
ARP34031 Human CENPE antibody; Homo sapiens CENPE antibody Q02224-2 100.0%
ARP33895 Human CENPE antibody; Homo sapiens CENPE antibody Q02224-3 100.0%
ARP33896 Human CENPE antibody; Homo sapiens CENPE antibody Q02224-3 100.0%
ARP33896 Mouse CENPE antibody; Mus musculus CENPE antibody Q6RT24 93.0%
ARP33896 Mouse CENPE antibody; Mus musculus CENPE antibody E9QKK1 93.0%
ARP34031 Northern white-cheeked gibbon CENPE antibody; Nomascus leucogenys CENPE antibody M3ZAZ8 100.0%
ARP33895 Northern white-cheeked gibbon CENPE antibody; Nomascus leucogenys CENPE antibody M3ZAZ8 92.0%
ARP33896 Pig CENPE antibody; Sus scrofa CENPE antibody I3LRD3 93.0%
ARP33895 Pig CENPE antibody; Sus scrofa CENPE antibody I3LRD3 86.0%
ARP33895 Rabbit CENPE antibody; Oryctolagus cuniculus CENPE antibody G1SDW0 93.0%
ARP33896 Rabbit CENPE antibody; Oryctolagus cuniculus CENPE antibody G1SDW0 86.0%
ARP34031 Rabbit CENPE antibody; Oryctolagus cuniculus CENPE antibody G1SDW0 79.0%
ARP33896 Rat CENPE antibody; Rattus norvegicus CENPE antibody D3ZV60 93.0%
ARP33895 Rhesus macaque CENPE antibody; Macaca mulatta CENPE antibody F6QD40 100.0%
ARP33896 Rhesus macaque CENPE antibody; Macaca mulatta CENPE antibody F6QD40 100.0%
ARP34031 Rhesus macaque CENPE antibody; Macaca mulatta CENPE antibody F6QD40 100.0%
ARP33895 Rhesus macaque CENPE antibody; Macaca mulatta CENPE antibody F7HML7 100.0%
ARP34031 Rhesus macaque CENPE antibody; Macaca mulatta CENPE antibody F7HML7 100.0%
ARP33896 Sumatran orangutan CENPE antibody; Pongo abelii CENPE antibody H2PE11 100.0%
ARP34031 Sumatran orangutan CENPE antibody; Pongo abelii CENPE antibody H2PE11 100.0%
ARP33895 Sumatran orangutan CENPE antibody; Pongo abelii CENPE antibody H2PE11 93.0%
ARP33896 Thirteen-lined ground squirrel CENPE antibody; Spermophilus tridecemlineatus CENPE antibody I3MWZ2 100.0%
ARP33895 Thirteen-lined ground squirrel CENPE antibody; Spermophilus tridecemlineatus CENPE antibody I3MWZ2 86.0%
ARP34031 Thirteen-lined ground squirrel CENPE antibody; Spermophilus tridecemlineatus CENPE antibody I3MWZ2 86.0%
ARP33895 White-tufted-ear marmoset CENPE antibody; Callithrix jacchus CENPE antibody F6WPJ7 100.0%
ARP33895 White-tufted-ear marmoset CENPE antibody; Callithrix jacchus CENPE antibody F6WPQ8 100.0%
ARP34031 White-tufted-ear marmoset CENPE antibody; Callithrix jacchus CENPE antibody F6WPJ7 93.0%
ARP34031 White-tufted-ear marmoset CENPE antibody; Callithrix jacchus CENPE antibody F6WPQ8 93.0%
ARP34031 White-tufted-ear marmoset CENPE antibody; Callithrix jacchus CENPE antibody F6XB86 93.0%
ARP33896 White-tufted-ear marmoset CENPE antibody; Callithrix jacchus CENPE antibody F6WPJ7 86.0%
ARP33896 White-tufted-ear marmoset CENPE antibody; Callithrix jacchus CENPE antibody F6WPQ8 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas205046_at721_B_lymphoblasts83.0507.020Details
BioGPS Gene Atlas205046_atAdipocyte3.7007.020Details
BioGPS Gene Atlas205046_atAdrenalCortex3.9007.020Details
BioGPS Gene Atlas205046_atAdrenalgland3.1007.020Details
BioGPS Gene Atlas205046_atAmygdala3.9007.020Details
BioGPS Gene Atlas205046_atAppendix3.8007.020Details
BioGPS Gene Atlas205046_atAtrioventricularNode2.8507.020Details
BioGPS Gene Atlas205046_atBDCA4+_DentriticCells4.1007.020Details
BioGPS Gene Atlas205046_atBonemarrow3.6507.020Details
BioGPS Gene Atlas205046_atBronchialEpithelialCells3.6507.020Details
BioGPS Gene Atlas205046_atCD105+_Endothelial27.2507.020Details
BioGPS Gene Atlas205046_atCD14+_Monocytes4.0007.020Details
BioGPS Gene Atlas205046_atCD19+_BCells(neg._sel.)3.9507.020Details
BioGPS Gene Atlas205046_atCD33+_Myeloid4.9007.020Details
BioGPS Gene Atlas205046_atCD34+8.4007.020Details
BioGPS Gene Atlas205046_atCD4+_Tcells4.0507.020Details
BioGPS Gene Atlas205046_atCD56+_NKCells4.5007.020Details
BioGPS Gene Atlas205046_atCD71+_EarlyErythroid112.5507.020Details
BioGPS Gene Atlas205046_atCD8+_Tcells3.6007.020Details
BioGPS Gene Atlas205046_atCardiacMyocytes10.7507.020Details
BioGPS Gene Atlas205046_atCaudatenucleus3.3507.020Details
BioGPS Gene Atlas205046_atCerebellum3.0007.020Details
BioGPS Gene Atlas205046_atCerebellumPeduncles4.2007.020Details
BioGPS Gene Atlas205046_atCiliaryGanglion2.6507.020Details
BioGPS Gene Atlas205046_atCingulateCortex3.8007.020Details
BioGPS Gene Atlas205046_atColorectaladenocarcinoma4.0007.020Details
BioGPS Gene Atlas205046_atDorsalRootGanglion3.5007.020Details
BioGPS Gene Atlas205046_atFetalThyroid3.6007.020Details
BioGPS Gene Atlas205046_atFetalbrain3.7007.020Details
BioGPS Gene Atlas205046_atFetalliver3.2507.020Details
BioGPS Gene Atlas205046_atFetallung3.0507.020Details
BioGPS Gene Atlas205046_atGlobusPallidus2.7507.020Details
BioGPS Gene Atlas205046_atHeart4.7507.020Details
BioGPS Gene Atlas205046_atHypothalamus4.0507.020Details
BioGPS Gene Atlas205046_atKidney3.0007.020Details
BioGPS Gene Atlas205046_atLeukemia_chronicMyelogenousK-5624.3007.020Details
BioGPS Gene Atlas205046_atLeukemia_promyelocytic-HL-6011.5007.020Details
BioGPS Gene Atlas205046_atLeukemialymphoblastic(MOLT-4)31.8007.020Details
BioGPS Gene Atlas205046_atLiver4.9007.020Details
BioGPS Gene Atlas205046_atLung4.1007.020Details
BioGPS Gene Atlas205046_atLymphnode3.1507.020Details
BioGPS Gene Atlas205046_atLymphoma_burkitts(Daudi)31.9007.020Details
BioGPS Gene Atlas205046_atLymphoma_burkitts(Raji)5.2007.020Details
BioGPS Gene Atlas205046_atMedullaOblongata3.4007.020Details
BioGPS Gene Atlas205046_atOccipitalLobe3.3507.020Details
BioGPS Gene Atlas205046_atOlfactoryBulb2.9507.020Details
BioGPS Gene Atlas205046_atOvary2.4507.020Details
BioGPS Gene Atlas205046_atPancreas3.0007.020Details
BioGPS Gene Atlas205046_atPancreaticIslet3.9507.020Details
BioGPS Gene Atlas205046_atParietalLobe3.9007.020Details
BioGPS Gene Atlas205046_atPituitary4.3507.020Details
BioGPS Gene Atlas205046_atPlacenta3.8507.020Details
BioGPS Gene Atlas205046_atPons3.5007.020Details
BioGPS Gene Atlas205046_atPrefrontalCortex4.6007.020Details
BioGPS Gene Atlas205046_atProstate4.3007.020Details
BioGPS Gene Atlas205046_atSalivarygland3.0007.020Details
BioGPS Gene Atlas205046_atSkeletalMuscle4.4507.020Details
BioGPS Gene Atlas205046_atSkin2.9507.020Details
BioGPS Gene Atlas205046_atSmoothMuscle4.2507.020Details
BioGPS Gene Atlas205046_atSpinalcord4.0007.020Details
BioGPS Gene Atlas205046_atSubthalamicNucleus3.4007.020Details
BioGPS Gene Atlas205046_atSuperiorCervicalGanglion4.3007.020Details
BioGPS Gene Atlas205046_atTemporalLobe3.4007.020Details
BioGPS Gene Atlas205046_atTestis3.2007.020Details
BioGPS Gene Atlas205046_atTestisGermCell3.2007.020Details
BioGPS Gene Atlas205046_atTestisIntersitial3.1507.020Details
BioGPS Gene Atlas205046_atTestisLeydigCell3.7007.020Details
BioGPS Gene Atlas205046_atTestisSeminiferousTubule3.2007.020Details
BioGPS Gene Atlas205046_atThalamus3.8007.020Details
BioGPS Gene Atlas205046_atThymus2.9507.020Details
BioGPS Gene Atlas205046_atThyroid4.6507.020Details
BioGPS Gene Atlas205046_atTongue3.7007.020Details
BioGPS Gene Atlas205046_atTonsil3.6007.020Details
BioGPS Gene Atlas205046_atTrachea3.1007.020Details
BioGPS Gene Atlas205046_atTrigeminalGanglion3.7507.020Details
BioGPS Gene Atlas205046_atUterus3.0507.020Details
BioGPS Gene Atlas205046_atUterusCorpus3.4007.020Details
BioGPS Gene Atlas205046_atWholeBlood4.0507.020Details
BioGPS Gene Atlas205046_atWholebrain3.1507.020Details
BioGPS Gene Atlas205046_atcolon3.7007.020Details
BioGPS Gene Atlas205046_atpineal_day4.6407.020Details
BioGPS Gene Atlas205046_atpineal_night4.5607.020Details
BioGPS Gene Atlas205046_atretina4.4757.020Details
BioGPS Gene Atlas205046_atsmall_intestine3.6007.020Details
BioGPS NCI60205046_at78643.16921.820Details
BioGPS NCI60205046_atA1724.11421.820Details
BioGPS NCI60205046_atA20465.99921.820Details
BioGPS NCI60205046_atA3616.03521.820Details
BioGPS NCI60205046_atA49826.39721.820Details
BioGPS NCI60205046_atA5496.24321.820Details
BioGPS NCI60205046_atACC34.89121.820Details
BioGPS NCI60205046_atACHN10.36721.820Details
BioGPS NCI60205046_atALVA3152.54521.820Details
BioGPS NCI60205046_atCAKI14.88221.820Details
BioGPS NCI60205046_atCCRT CEM56.56521.820Details
BioGPS NCI60205046_atCOLO20522.14221.820Details
BioGPS NCI60205046_atDLD111.04621.820Details
BioGPS NCI60205046_atDU14561.75321.820Details
BioGPS NCI60205046_atEKVX134.34921.820Details
BioGPS NCI60205046_atGM13310.74421.820Details
BioGPS NCI60205046_atGM16004.62121.820Details
BioGPS NCI60205046_atGM231311.24521.820Details
BioGPS NCI60205046_atGM234532.44721.820Details
BioGPS NCI60205046_atGM24934.66921.820Details
BioGPS NCI60205046_atGM974.97721.820Details
BioGPS NCI60205046_atHCC299823.35921.820Details
BioGPS NCI60205046_atHCT11624.07621.820Details
BioGPS NCI60205046_atHCT1511.26321.820Details
BioGPS NCI60205046_atHEK 293 T-rex12.86321.820Details
BioGPS NCI60205046_atHEK 293T24.77521.820Details
BioGPS NCI60205046_atHEK29311.49821.820Details
BioGPS NCI60205046_atHELA36.03121.820Details
BioGPS NCI60205046_atHEPG214.53221.820Details
BioGPS NCI60205046_atHL6013.23221.820Details
BioGPS NCI60205046_atHOP6233.09621.820Details
BioGPS NCI60205046_atHOP924.22021.820Details
BioGPS NCI60205046_atHS578T40.06621.820Details
BioGPS NCI60205046_atHSG6.69921.820Details
BioGPS NCI60205046_atHT10804.08321.820Details
BioGPS NCI60205046_atHT295.73221.820Details
BioGPS NCI60205046_atIGROV111.24521.820Details
BioGPS NCI60205046_atIOSE8096.18921.820Details
BioGPS NCI60205046_atJURKAT69.82521.820Details
BioGPS NCI60205046_atK56211.85021.820Details
BioGPS NCI60205046_atKM1227.00321.820Details
BioGPS NCI60205046_atLN184.43421.820Details
BioGPS NCI60205046_atLNCAP8.48421.820Details
BioGPS NCI60205046_atLOX IMVI4.78021.820Details
BioGPS NCI60205046_atM1417.88221.820Details
BioGPS NCI60205046_atMALME 3M4.55221.820Details
BioGPS NCI60205046_atMCF75.92121.820Details
BioGPS NCI60205046_atMD MB23170.74621.820Details
BioGPS NCI60205046_atMDA MB4354.18321.820Details
BioGPS NCI60205046_atMOLT414.24621.820Details
BioGPS NCI60205046_atNCI 46023.06821.820Details
BioGPS NCI60205046_atNCI H2267.55921.820Details
BioGPS NCI60205046_atNCI H2310.47921.820Details
BioGPS NCI60205046_atNCI H322M30.57921.820Details
BioGPS NCI60205046_atNCVADR RES16.33921.820Details
BioGPS NCI60205046_atOVCAR313.58521.820Details
BioGPS NCI60205046_atOVCAR458.15521.820Details
BioGPS NCI60205046_atOVCAR567.19821.820Details
BioGPS NCI60205046_atOVCAR880.83521.820Details
BioGPS NCI60205046_atPANC14.32421.820Details
BioGPS NCI60205046_atRL737.46421.820Details
BioGPS NCI60205046_atRPMI 82264.47721.820Details
BioGPS NCI60205046_atRS1184632.45421.820Details
BioGPS NCI60205046_atRXF39314.84121.820Details
BioGPS NCI60205046_atSAOS229.66221.820Details
BioGPS NCI60205046_atSF26816.16921.820Details
BioGPS NCI60205046_atSF29512.17421.820Details
BioGPS NCI60205046_atSF53953.50021.820Details
BioGPS NCI60205046_atSHSYSY+RA13.38621.820Details
BioGPS NCI60205046_atSHSYSY-RA4.77621.820Details
BioGPS NCI60205046_atSKMEL212.53921.820Details
BioGPS NCI60205046_atSKMEL284.35821.820Details
BioGPS NCI60205046_atSKMEL54.03121.820Details
BioGPS NCI60205046_atSKOV380.59021.820Details
BioGPS NCI60205046_atSN12C8.58321.820Details
BioGPS NCI60205046_atSNB1922.98121.820Details
BioGPS NCI60205046_atSNB759.46821.820Details
BioGPS NCI60205046_atSR46.69121.820Details
BioGPS NCI60205046_atSW6209.11721.820Details
BioGPS NCI60205046_atT2421.86621.820Details
BioGPS NCI60205046_atT3M422.57521.820Details
BioGPS NCI60205046_atTK1034.60221.820Details
BioGPS NCI60205046_atU1189.28421.820Details
BioGPS NCI60205046_atU13821.55521.820Details
BioGPS NCI60205046_atU20S11.26421.820Details
BioGPS NCI60205046_atU25140.49021.820Details
BioGPS NCI60205046_atU8712.22621.820Details
BioGPS NCI60205046_atUACC2574.28621.820Details
BioGPS NCI60205046_atUACC624.19521.820Details
BioGPS NCI60205046_atUO3149.38421.820Details
BioGPS NCI60205046_atZR75_111.68221.820Details
BioGPS NCI60205046_atastrocytes4.35121.820Details
BioGPS NCI60205046_athuh-75.80921.820Details