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Gene ID: 1059 | CENPB Antibody Resource


CENPB Antibody Resource
Gene Full Name: 
centromere protein B, 80kDa
Uniprot: 
P07199
Protein Name: 
major centromere autoantigen B
Nucleotide: 
NM_001810
Alias: 
Ensembl: 
ENSG00000125817
Location: 
20p13
HPRD: 
00314
NCBI Gene: 
1059
MIM: 
117140

Summary: 
This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. [provided by RefSeq, Jul 2008]
Function: 
Interacts with centromeric heterochromatin in chromosomes and binds to a specific subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes.
Subcellular location: 
Nucleus. Chromosome › centromere .
PTM: 
ADP-ribosylation;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP51969_P050 CENPB antibody - C-terminal region (ARP51969_P050) Polyclonal Dog, Horse, Human, Mouse, Pig, Rat, Sheep WB 50ug $289 Details
Protein OPPA01302 CENPB Human - Recombinant Human Centromere Protein-B (5ug) WB 5ug $100 Details

Show all CENPB antibodies


Product Images
CENPB antibody - C-terminal region (ARP51969_P050) in Human Jurkat cells using Western Blot

Sample Type: Human Jurkat


CENPB Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP51969 Chimpanzee CENPB antibody; Pan troglodytes CENPB antibody H2REE5 100.0%
ARP51969 Chinese hamster CENPB antibody; Cricetulus griseus CENPB antibody P48988 93.0%
ARP51969 Duckbill platypus CENPB antibody; Ornithorhynchus anatinus CENPB antibody F6WAY4 79.0%
ARP51969 European domestic ferret CENPB antibody; Mustela putorius furo CENPB antibody M3Z607 86.0%
ARP41235 Gray short-tailed opossum CENPB antibody; Monodelphis domestica CENPB antibody F6WYF8 92.0%
ARP38629 Horse CENPB antibody; Equus caballus CENPB antibody F6PI44 86.0%
ARP51969 Horse CENPB antibody; Equus caballus CENPB antibody F6PI44 86.0%
ARP41218 Horse CENPB antibody; Equus caballus CENPB antibody F6PI44 79.0%
ARP43485 Horse CENPB antibody; Equus caballus CENPB antibody F6PI44 79.0%
ARP51969 Human CENPB antibody; Homo sapiens CENPB antibody P07199 100.0%
ARP38404 Human CENPB antibody; Homo sapiens CENPB antibody P07199 90.0%
ARP51969 Mouse CENPB antibody; Mus musculus CENPB antibody Q3TY85 93.0%
ARP51969 Mouse CENPB antibody; Mus musculus CENPB antibody Q923C5 93.0%
ARP51969 Mouse CENPB antibody; Mus musculus CENPB antibody P27790 93.0%
ARP43485 Mouse CENPB antibody; Mus musculus CENPB antibody Q3TY85 80.0%
ARP51969 Northern white-cheeked gibbon CENPB antibody; Nomascus leucogenys CENPB antibody G1SAA6 100.0%
ARP38404 Northern white-cheeked gibbon CENPB antibody; Nomascus leucogenys CENPB antibody G1SAA6 90.0%
ARP51969 Rat CENPB antibody; Rattus norvegicus CENPB antibody D4A5E3 93.0%
ARP51969 Rhesus macaque CENPB antibody; Macaca mulatta CENPB antibody F6QSG7 100.0%
ARP51969 Rhesus macaque CENPB antibody; Macaca mulatta CENPB antibody I2CTV5 100.0%
ARP38404 Rhesus macaque CENPB antibody; Macaca mulatta CENPB antibody F6QSG7 90.0%
ARP38404 Rhesus macaque CENPB antibody; Macaca mulatta CENPB antibody I2CTV5 90.0%
ARP51969 Sheep CENPB antibody; Ovis aries CENPB antibody P49451 86.0%
ARP43485 Sheep CENPB antibody; Ovis aries CENPB antibody P49451 79.0%
ARP43485 Small-eared galago CENPB antibody; Otolemur garnettii CENPB antibody H0XP85 86.0%
ARP51969 Small-eared galago CENPB antibody; Otolemur garnettii CENPB antibody H0XP85 86.0%
ARP51969 Thirteen-lined ground squirrel CENPB antibody; Spermophilus tridecemlineatus CENPB antibody I3N785 93.0%
ARP43485 Thirteen-lined ground squirrel CENPB antibody; Spermophilus tridecemlineatus CENPB antibody I3N785 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas212437_at721_B_lymphoblasts54.45031.580Details
BioGPS Gene Atlas212437_atAdipocyte27.75031.580Details
BioGPS Gene Atlas212437_atAdrenalCortex30.45031.580Details
BioGPS Gene Atlas212437_atAdrenalgland25.15031.580Details
BioGPS Gene Atlas212437_atAmygdala35.75031.580Details
BioGPS Gene Atlas212437_atAppendix28.35031.580Details
BioGPS Gene Atlas212437_atAtrioventricularNode24.60031.580Details
BioGPS Gene Atlas212437_atBDCA4+_DentriticCells29.80031.580Details
BioGPS Gene Atlas212437_atBonemarrow27.60031.580Details
BioGPS Gene Atlas212437_atBronchialEpithelialCells26.70031.580Details
BioGPS Gene Atlas212437_atCD105+_Endothelial27.95031.580Details
BioGPS Gene Atlas212437_atCD14+_Monocytes40.00031.580Details
BioGPS Gene Atlas212437_atCD19+_BCells(neg._sel.)28.85031.580Details
BioGPS Gene Atlas212437_atCD33+_Myeloid34.45031.580Details
BioGPS Gene Atlas212437_atCD34+33.75031.580Details
BioGPS Gene Atlas212437_atCD4+_Tcells28.50031.580Details
BioGPS Gene Atlas212437_atCD56+_NKCells34.65031.580Details
BioGPS Gene Atlas212437_atCD71+_EarlyErythroid25.25031.580Details
BioGPS Gene Atlas212437_atCD8+_Tcells25.30031.580Details
BioGPS Gene Atlas212437_atCardiacMyocytes46.00031.580Details
BioGPS Gene Atlas212437_atCaudatenucleus26.40031.580Details
BioGPS Gene Atlas212437_atCerebellum26.45031.580Details
BioGPS Gene Atlas212437_atCerebellumPeduncles31.80031.580Details
BioGPS Gene Atlas212437_atCiliaryGanglion19.80031.580Details
BioGPS Gene Atlas212437_atCingulateCortex28.70031.580Details
BioGPS Gene Atlas212437_atColorectaladenocarcinoma33.85031.580Details
BioGPS Gene Atlas212437_atDorsalRootGanglion21.95031.580Details
BioGPS Gene Atlas212437_atFetalThyroid37.25031.580Details
BioGPS Gene Atlas212437_atFetalbrain28.75031.580Details
BioGPS Gene Atlas212437_atFetalliver22.35031.580Details
BioGPS Gene Atlas212437_atFetallung21.30031.580Details
BioGPS Gene Atlas212437_atGlobusPallidus31.10031.580Details
BioGPS Gene Atlas212437_atHeart66.55031.580Details
BioGPS Gene Atlas212437_atHypothalamus30.15031.580Details
BioGPS Gene Atlas212437_atKidney28.10031.580Details
BioGPS Gene Atlas212437_atLeukemia_chronicMyelogenousK-56223.20031.580Details
BioGPS Gene Atlas212437_atLeukemia_promyelocytic-HL-6022.25031.580Details
BioGPS Gene Atlas212437_atLeukemialymphoblastic(MOLT-4)53.95031.580Details
BioGPS Gene Atlas212437_atLiver40.80031.580Details
BioGPS Gene Atlas212437_atLung57.90031.580Details
BioGPS Gene Atlas212437_atLymphnode24.20031.580Details
BioGPS Gene Atlas212437_atLymphoma_burkitts(Daudi)35.65031.580Details
BioGPS Gene Atlas212437_atLymphoma_burkitts(Raji)39.05031.580Details
BioGPS Gene Atlas212437_atMedullaOblongata24.65031.580Details
BioGPS Gene Atlas212437_atOccipitalLobe26.20031.580Details
BioGPS Gene Atlas212437_atOlfactoryBulb21.60031.580Details
BioGPS Gene Atlas212437_atOvary19.05031.580Details
BioGPS Gene Atlas212437_atPancreas21.20031.580Details
BioGPS Gene Atlas212437_atPancreaticIslet29.65031.580Details
BioGPS Gene Atlas212437_atParietalLobe30.30031.580Details
BioGPS Gene Atlas212437_atPituitary31.60031.580Details
BioGPS Gene Atlas212437_atPlacenta30.60031.580Details
BioGPS Gene Atlas212437_atPons26.30031.580Details
BioGPS Gene Atlas212437_atPrefrontalCortex67.75031.580Details
BioGPS Gene Atlas212437_atProstate43.60031.580Details
BioGPS Gene Atlas212437_atSalivarygland21.45031.580Details
BioGPS Gene Atlas212437_atSkeletalMuscle33.25031.580Details
BioGPS Gene Atlas212437_atSkin23.85031.580Details
BioGPS Gene Atlas212437_atSmoothMuscle34.85031.580Details
BioGPS Gene Atlas212437_atSpinalcord41.15031.580Details
BioGPS Gene Atlas212437_atSubthalamicNucleus26.05031.580Details
BioGPS Gene Atlas212437_atSuperiorCervicalGanglion34.15031.580Details
BioGPS Gene Atlas212437_atTemporalLobe25.50031.580Details
BioGPS Gene Atlas212437_atTestis23.65031.580Details
BioGPS Gene Atlas212437_atTestisGermCell21.60031.580Details
BioGPS Gene Atlas212437_atTestisIntersitial22.70031.580Details
BioGPS Gene Atlas212437_atTestisLeydigCell27.60031.580Details
BioGPS Gene Atlas212437_atTestisSeminiferousTubule23.40031.580Details
BioGPS Gene Atlas212437_atThalamus34.70031.580Details
BioGPS Gene Atlas212437_atThymus22.95031.580Details
BioGPS Gene Atlas212437_atThyroid61.05031.580Details
BioGPS Gene Atlas212437_atTongue28.65031.580Details
BioGPS Gene Atlas212437_atTonsil26.10031.580Details
BioGPS Gene Atlas212437_atTrachea23.70031.580Details
BioGPS Gene Atlas212437_atTrigeminalGanglion28.60031.580Details
BioGPS Gene Atlas212437_atUterus22.60031.580Details
BioGPS Gene Atlas212437_atUterusCorpus27.60031.580Details
BioGPS Gene Atlas212437_atWholeBlood44.40031.580Details
BioGPS Gene Atlas212437_atWholebrain39.05031.580Details
BioGPS Gene Atlas212437_atcolon33.25031.580Details
BioGPS Gene Atlas212437_atpineal_day32.90031.580Details
BioGPS Gene Atlas212437_atpineal_night32.06031.580Details
BioGPS Gene Atlas212437_atretina38.72531.580Details
BioGPS Gene Atlas212437_atsmall_intestine28.05031.580Details
BioGPS NCI60212437_at786155.484408.860Details
BioGPS NCI60212437_atA172292.140408.860Details
BioGPS NCI60212437_atA204252.697408.860Details
BioGPS NCI60212437_atA361394.317408.860Details
BioGPS NCI60212437_atA498106.241408.860Details
BioGPS NCI60212437_atA549255.550408.860Details
BioGPS NCI60212437_atACC3262.723408.860Details
BioGPS NCI60212437_atACHN296.174408.860Details
BioGPS NCI60212437_atALVA31222.072408.860Details
BioGPS NCI60212437_atCAKI170.862408.860Details
BioGPS NCI60212437_atCCRT CEM195.892408.860Details
BioGPS NCI60212437_atCOLO205162.013408.860Details
BioGPS NCI60212437_atDLD1599.990408.860Details
BioGPS NCI60212437_atDU145134.545408.860Details
BioGPS NCI60212437_atEKVX1071.161408.860Details
BioGPS NCI60212437_atGM133255.655408.860Details
BioGPS NCI60212437_atGM1600255.844408.860Details
BioGPS NCI60212437_atGM2313383.450408.860Details
BioGPS NCI60212437_atGM2345387.211408.860Details
BioGPS NCI60212437_atGM2493256.140408.860Details
BioGPS NCI60212437_atGM97376.697408.860Details
BioGPS NCI60212437_atHCC2998637.283408.860Details
BioGPS NCI60212437_atHCT116138.381408.860Details
BioGPS NCI60212437_atHCT15115.679408.860Details
BioGPS NCI60212437_atHEK 293 T-rex125.563408.860Details
BioGPS NCI60212437_atHEK 293T252.506408.860Details
BioGPS NCI60212437_atHEK293198.963408.860Details
BioGPS NCI60212437_atHELA728.529408.860Details
BioGPS NCI60212437_atHEPG2364.397408.860Details
BioGPS NCI60212437_atHL60141.210408.860Details
BioGPS NCI60212437_atHOP62178.620408.860Details
BioGPS NCI60212437_atHOP92774.325408.860Details
BioGPS NCI60212437_atHS578T701.757408.860Details
BioGPS NCI60212437_atHSG249.060408.860Details
BioGPS NCI60212437_atHT108075.975408.860Details
BioGPS NCI60212437_atHT29434.502408.860Details
BioGPS NCI60212437_atIGROV1486.681408.860Details
BioGPS NCI60212437_atIOSE80495.495408.860Details
BioGPS NCI60212437_atJURKAT252.793408.860Details
BioGPS NCI60212437_atK562157.966408.860Details
BioGPS NCI60212437_atKM12261.960408.860Details
BioGPS NCI60212437_atLN18596.981408.860Details
BioGPS NCI60212437_atLNCAP252.060408.860Details
BioGPS NCI60212437_atLOX IMVI144.430408.860Details
BioGPS NCI60212437_atM14637.608408.860Details
BioGPS NCI60212437_atMALME 3M352.175408.860Details
BioGPS NCI60212437_atMCF7780.533408.860Details
BioGPS NCI60212437_atMD MB231199.268408.860Details
BioGPS NCI60212437_atMDA MB435396.885408.860Details
BioGPS NCI60212437_atMOLT4561.565408.860Details
BioGPS NCI60212437_atNCI 460149.503408.860Details
BioGPS NCI60212437_atNCI H226112.525408.860Details
BioGPS NCI60212437_atNCI H23171.306408.860Details
BioGPS NCI60212437_atNCI H322M80.470408.860Details
BioGPS NCI60212437_atNCVADR RES416.404408.860Details
BioGPS NCI60212437_atOVCAR31019.972408.860Details
BioGPS NCI60212437_atOVCAR4152.459408.860Details
BioGPS NCI60212437_atOVCAR5481.253408.860Details
BioGPS NCI60212437_atOVCAR81754.850408.860Details
BioGPS NCI60212437_atPANC1377.779408.860Details
BioGPS NCI60212437_atRL764.470408.860Details
BioGPS NCI60212437_atRPMI 8226128.891408.860Details
BioGPS NCI60212437_atRS11846160.641408.860Details
BioGPS NCI60212437_atRXF393691.454408.860Details
BioGPS NCI60212437_atSAOS2346.234408.860Details
BioGPS NCI60212437_atSF268564.382408.860Details
BioGPS NCI60212437_atSF2951371.595408.860Details
BioGPS NCI60212437_atSF539815.261408.860Details
BioGPS NCI60212437_atSHSYSY+RA430.380408.860Details
BioGPS NCI60212437_atSHSYSY-RA415.097408.860Details
BioGPS NCI60212437_atSKMEL2585.261408.860Details
BioGPS NCI60212437_atSKMEL28423.845408.860Details
BioGPS NCI60212437_atSKMEL5435.156408.860Details
BioGPS NCI60212437_atSKOV3156.908408.860Details
BioGPS NCI60212437_atSN12C215.732408.860Details
BioGPS NCI60212437_atSNB19553.792408.860Details
BioGPS NCI60212437_atSNB75461.926408.860Details
BioGPS NCI60212437_atSR256.019408.860Details
BioGPS NCI60212437_atSW620176.404408.860Details
BioGPS NCI60212437_atT241738.853408.860Details
BioGPS NCI60212437_atT3M4257.963408.860Details
BioGPS NCI60212437_atTK10325.024408.860Details
BioGPS NCI60212437_atU1181704.080408.860Details
BioGPS NCI60212437_atU1381152.578408.860Details
BioGPS NCI60212437_atU20S280.325408.860Details
BioGPS NCI60212437_atU251789.471408.860Details
BioGPS NCI60212437_atU87244.264408.860Details
BioGPS NCI60212437_atUACC257347.325408.860Details
BioGPS NCI60212437_atUACC62255.744408.860Details
BioGPS NCI60212437_atUO31462.726408.860Details
BioGPS NCI60212437_atZR75_1111.120408.860Details
BioGPS NCI60212437_atastrocytes254.296408.860Details
BioGPS NCI60212437_athuh-7259.121408.860Details