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Gene ID: 64072 | CDH23 Antibody Resource


CDH23 Antibody Resource
Gene Full Name: 
cadherin-related 23
Uniprot: 
Q9H251
Protein Name: 
cadherin-23
Nucleotide: 
NM_022124
Alias: 
USH1D;CDHR23;
Ensembl: 
ENSG00000107736
Location: 
10q22.1
HPRD: 
05699
NCBI Gene: 
64072
MIM: 
605516

Summary: 
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013]
Function: 
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
Subcellular location: 
Cell membrane; Single-pass type I membrane protein.
PTM: 
Glycoprotein;
Disease: 
Usher syndrome 1D (USH1D) [MIM:601067]: USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa with sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). USH1 is characterized by profound congenital sensorineural deafness, absent vestibular function and prepubertal onset of progressive retinitis pigmentosa leading to blindness. Note: The disease is caused by mutations affecting the gene represented in this entry. Usher syndrome 1D/F (USH1DF) [MIM:601067]: USH1DF patients are heterozygous for mutations in CDH23 and PCDH15, indicating a digenic inheritance pattern. Note: The disease is caused by mutations affecting distinct genetic loci, including the gene represented in this entry. Deafness, autosomal recessive, 12 (DFNB12) [MIM:601386]: A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP49690_P050 CDH23 antibody - middle region (ARP49690_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish WB 50ug $289 Details
Polyclonal Antibody OAEB01109 Goat Anti-CDH23 / USH1D Antibody (OAEB01109) Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rabbit, Rat WB 0.1mg $289 Details
Polyclonal Antibody ARP49689_P050 CDH23 Antibody - N-terminal region (ARP49689_P050) Polyclonal Human WB 50ug $289 Details
Polyclonal Antibody OAAF02851 CDH23 Antibody (OAAF02851) Polyclonal Human, Mouse, Rat IF, ELISA 100 ug $229 Details

Show all CDH23 antibodies


Product Images
CDH23 Antibody - N-terminal region (ARP49689_P050) in Human Fetal Brain cells using Western Blot

Sample Type: Human Fetal Brain

CDH23 antibody - middle region (ARP49690_P050) in Human OVCAR-3 cells using Western Blot

Sample Type: Human OVCAR-3

CDH23 Antibody (OAAF02851) in HeLa cells using Immunofluorescence

Sample Type: HeLa

Goat Anti-CDH23 / USH1D Antibody (OAEB01109) in Human Amygdala cells using Western Blot

Sample Type: Human Amygdala


CDH23 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP49689 Hipposideros larvatus CDH23 antibody G3GAX7 100.0%
ARP49690 Hipposideros larvatus CDH23 antibody G3GAX7 100.0%
ARP49689 Myotis altarium CDH23 antibody G3GAX9 100.0%
ARP49690 Myotis altarium CDH23 antibody G3GAX9 100.0%
ARP49689 Chaerephon plicatus CDH23 antibody G3GAY0 100.0%
ARP49690 Chaerephon plicatus CDH23 antibody G3GAY0 100.0%
ARP49690 African elephant CDH23 antibody; Loxodonta africana CDH23 antibody G3TEM8 100.0%
ARP49690 African elephant CDH23 antibody; Loxodonta africana CDH23 antibody G3UNP5 100.0%
ARP49689 Black-bearded tomb bat CDH23 antibody; Taphozous melanopogon CDH23 antibody G3GAY2 100.0%
ARP49690 Black-bearded tomb bat CDH23 antibody; Taphozous melanopogon CDH23 antibody G3GAY2 100.0%
ARP49689 Bovine CDH23 antibody; Bos taurus CDH23 antibody F1MXP9 100.0%
ARP49690 Bovine CDH23 antibody; Bos taurus CDH23 antibody F1MXP9 100.0%
ARP49689 Cat CDH23 antibody; Felis catus CDH23 antibody M3X632 100.0%
ARP49690 Cat CDH23 antibody; Felis catus CDH23 antibody M3X632 100.0%
ARP49384 Chimpanzee CDH23 antibody; Pan troglodytes CDH23 antibody H2QQB2 85.0%
ARP49689 Dog CDH23 antibody; Canis familiaris CDH23 antibody F1P8X5 100.0%
ARP49690 Dog CDH23 antibody; Canis familiaris CDH23 antibody F1P8X5 100.0%
ARP49689 European domestic ferret CDH23 antibody; Mustela putorius furo CDH23 antibody M3XYD7 100.0%
ARP49690 European domestic ferret CDH23 antibody; Mustela putorius furo CDH23 antibody M3XYD7 100.0%
ARP49341 European domestic ferret CDH23 antibody; Mustela putorius furo CDH23 antibody M3XYD7 85.0%
ARP49690 Gray short-tailed opossum CDH23 antibody; Monodelphis domestica CDH23 antibody H9H9M3 93.0%
ARP49689 great roundleaf bat CDH23 antibody; Hipposideros armiger CDH23 antibody G3GAY1 100.0%
ARP49690 great roundleaf bat CDH23 antibody; Hipposideros armiger CDH23 antibody G3GAY1 100.0%
ARP49689 Horse CDH23 antibody; Equus caballus CDH23 antibody F6XLL6 100.0%
ARP49689 Horse CDH23 antibody; Equus caballus CDH23 antibody F6XLQ0 100.0%
ARP49689 Horse CDH23 antibody; Equus caballus CDH23 antibody F6XRV0 100.0%
ARP49689 Horse CDH23 antibody; Equus caballus CDH23 antibody F6XRX6 100.0%
ARP49690 Horse CDH23 antibody; Equus caballus CDH23 antibody F6XLL6 93.0%
ARP49690 Horse CDH23 antibody; Equus caballus CDH23 antibody F6XLQ0 93.0%
ARP49690 Horse CDH23 antibody; Equus caballus CDH23 antibody F6XRV0 93.0%
ARP49690 Horse CDH23 antibody; Equus caballus CDH23 antibody F6XRX6 93.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody G8JLI8 100.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody R4GN92 100.0%
ARP49689 Human CDH23 antibody; Homo sapiens CDH23 antibody Q32P55 100.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody Q32P55 100.0%
ARP49689 Human CDH23 antibody; Homo sapiens CDH23 antibody Q6P152 100.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody Q6P152 100.0%
ARP49689 Human CDH23 antibody; Homo sapiens CDH23 antibody Q8N5B3 100.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody Q8N5B3 100.0%
ARP49689 Human CDH23 antibody; Homo sapiens CDH23 antibody Q9H251-2 100.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody Q9H251-2 100.0%
ARP49689 Human CDH23 antibody; Homo sapiens CDH23 antibody Q9H251-3 100.0%
ARP49689 Human CDH23 antibody; Homo sapiens CDH23 antibody A5D6V9 100.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody A5D6V9 100.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody Q9H251-3 100.0%
ARP49689 Human CDH23 antibody; Homo sapiens CDH23 antibody Q9H251-4 100.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody Q9H251-4 100.0%
ARP49689 Human CDH23 antibody; Homo sapiens CDH23 antibody Q9H251-5 100.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody Q9H251-5 100.0%
ARP49689 Human CDH23 antibody; Homo sapiens CDH23 antibody Q9H251-6 100.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody Q9H251-6 100.0%
ARP49689 Human CDH23 antibody; Homo sapiens CDH23 antibody Q9H251-8 100.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody Q9H251-8 100.0%
ARP49689 Human CDH23 antibody; Homo sapiens CDH23 antibody Q9H251 100.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody Q9H251 100.0%
ARP49689 Human CDH23 antibody; Homo sapiens CDH23 antibody R4GN22 100.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody R4GN22 100.0%
ARP49689 Human CDH23 antibody; Homo sapiens CDH23 antibody G3XCN8 100.0%
ARP49690 Human CDH23 antibody; Homo sapiens CDH23 antibody G3XCN8 100.0%
ARP49689 Human CDH23 antibody; Homo sapiens CDH23 antibody G8JLI8 100.0%
ARP49689 Leschenault's rousette CDH23 antibody; Rousettus leschenaultii CDH23 antibody G3GAY3 100.0%
ARP49690 Leschenault's rousette CDH23 antibody; Rousettus leschenaultii CDH23 antibody G3GAY3 100.0%
ARP49689 Lesser dawn bat CDH23 antibody; Eonycteris spelaea CDH23 antibody G3GAX8 100.0%
ARP49690 Lesser dawn bat CDH23 antibody; Eonycteris spelaea CDH23 antibody G3GAX8 100.0%
ARP49689 Mouse CDH23 antibody; Mus musculus CDH23 antibody F8WIF5 100.0%
ARP49690 Mouse CDH23 antibody; Mus musculus CDH23 antibody F8WIF5 100.0%
ARP49689 Mouse CDH23 antibody; Mus musculus CDH23 antibody K4DI74 100.0%
ARP49690 Mouse CDH23 antibody; Mus musculus CDH23 antibody K4DI74 100.0%
ARP49689 Mouse CDH23 antibody; Mus musculus CDH23 antibody Q5DUA3 100.0%
ARP49689 Mouse CDH23 antibody; Mus musculus CDH23 antibody Q5DUA4 100.0%
ARP49689 Mouse CDH23 antibody; Mus musculus CDH23 antibody Q5DUA5 100.0%
ARP49689 Mouse CDH23 antibody; Mus musculus CDH23 antibody Q99PF4-2 100.0%
ARP49690 Mouse CDH23 antibody; Mus musculus CDH23 antibody Q99PF4-2 100.0%
ARP49689 Mouse CDH23 antibody; Mus musculus CDH23 antibody Q99PF4 100.0%
ARP49690 Mouse CDH23 antibody; Mus musculus CDH23 antibody Q99PF4 100.0%
ARP49689 Mouse CDH23 antibody; Mus musculus CDH23 antibody B8QRJ1 100.0%
ARP49689 Mouse CDH23 antibody; Mus musculus CDH23 antibody B8QRJ2 100.0%
ARP49689 Mouse CDH23 antibody; Mus musculus CDH23 antibody E9Q7M6 100.0%
ARP49690 Mouse CDH23 antibody; Mus musculus CDH23 antibody E9Q7M6 100.0%
ARP49690 Mouse CDH23 antibody; Mus musculus CDH23 antibody Q5DUA3 93.0%
ARP49690 Mouse CDH23 antibody; Mus musculus CDH23 antibody Q5DUA4 93.0%
ARP49690 Mouse CDH23 antibody; Mus musculus CDH23 antibody Q5DUA5 93.0%
ARP49690 Mouse CDH23 antibody; Mus musculus CDH23 antibody B8QRJ1 93.0%
ARP49690 Mouse CDH23 antibody; Mus musculus CDH23 antibody B8QRJ2 92.0%
ARP49689 Pig CDH23 antibody; Sus scrofa CDH23 antibody F1SUA7 100.0%
ARP49690 Pig CDH23 antibody; Sus scrofa CDH23 antibody F1SUA7 100.0%
ARP49689 Rat CDH23 antibody; Rattus norvegicus CDH23 antibody P58365 100.0%
ARP49690 Rat CDH23 antibody; Rattus norvegicus CDH23 antibody P58365 93.0%
ARP49689 Schreibers's long-fingered bat CDH23 antibody; Miniopterus schreibersii CDH23 antibody G3GAX5 100.0%
ARP49690 Schreibers's long-fingered bat CDH23 antibody; Miniopterus schreibersii CDH23 antibody G3GAX5 100.0%
ARP49689 Stoliczka's Asian trident bat CDH23 antibody; Aselliscus stoliczkanus CDH23 antibody G3GAX6 100.0%
ARP49690 Stoliczka's Asian trident bat CDH23 antibody; Aselliscus stoliczkanus CDH23 antibody G3GAX6 100.0%
ARP51289 West Indian ocean coelacanth CDH23 antibody; Latimeria chalumnae CDH23 antibody H3AWD9 79.0%
ARP49690 White-tufted-ear marmoset CDH23 antibody; Callithrix jacchus CDH23 antibody F7BIA7 100.0%
ARP49689 White-tufted-ear marmoset CDH23 antibody; Callithrix jacchus CDH23 antibody F7BJ49 100.0%
ARP49690 White-tufted-ear marmoset CDH23 antibody; Callithrix jacchus CDH23 antibody F7BJ49 100.0%
ARP49689 White-tufted-ear marmoset CDH23 antibody; Callithrix jacchus CDH23 antibody F7BI73 100.0%
ARP49690 White-tufted-ear marmoset CDH23 antibody; Callithrix jacchus CDH23 antibody F7BI73 100.0%
ARP49689 White-tufted-ear marmoset CDH23 antibody; Callithrix jacchus CDH23 antibody F7BIA7 100.0%
ARP49690 Zebra finch CDH23 antibody; Taeniopygia guttata CDH23 antibody H0Z1B9 93.0%
ARP49689 Zebra finch CDH23 antibody; Taeniopygia guttata CDH23 antibody H0Z1B9 86.0%
ARP49690 Zebrafish CDH23 antibody; Danio rerio CDH23 antibody Q6QQE1 86.0%
ARP49690 Zebrafish CDH23 antibody; Danio rerio CDH23 antibody F1R7G8 86.0%

Tissue & Cell Line Gene Expression Data