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Gene ID: 148170 | CDC42EP5 Antibody Resource


CDC42EP5 Antibody Resource
Gene Full Name: 
CDC42 effector protein (Rho GTPase binding) 5
Uniprot: 
Q6NZY7
Protein Name: 
cdc42 effector protein 5
Nucleotide: 
NM_145057
Alias: 
CEP5;Borg3;
Ensembl: 
ENSG00000167617
Location: 
19q13.42
HPRD: 
13023
NCBI Gene: 
148170
MIM: 
609171

Summary: 
Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013]
Function: 
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42 .
Subcellular location: 
Endomembrane system; Peripheral membrane protein. Cytoplasm › cytoskeleton.
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP52797_P050 CDC42EP5 antibody - middle region (ARP52797_P050) Polyclonal Bovine, Mouse, Pig, Rat WB 50ug $289 Details
Polyclonal Antibody ARP52796_P050 CDC42EP5 Antibody (ARP52796_P050) Polyclonal Bovine, Horse, Human, Mouse, Pig, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAF03457 CDC42EP5 Antibody (OAAF03457) Polyclonal Human, Mouse WB, ELISA 100 ug $289 Details

Show all CDC42EP5 antibodies


Product Images
CDC42EP5 antibody - middle region (ARP52797_P050) in Transfected 293T cells using Western Blot

Sample Type: Transfected 293T

CDC42EP5 Antibody (OAAF03457) in Jurkat cells using Western Blot

Sample Type: Jurkat


CDC42EP5 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP52797 Bovine CDC42EP5 antibody; Bos taurus CDC42EP5 antibody G3N010 100.0%
ARP52796 Bovine CDC42EP5 antibody; Bos taurus CDC42EP5 antibody G3N010 93.0%
ARP52796 Chimpanzee CDC42EP5 antibody; Pan troglodytes CDC42EP5 antibody H2R5U9 100.0%
ARP52797 Chimpanzee CDC42EP5 antibody; Pan troglodytes CDC42EP5 antibody H2R5U9 100.0%
ARP52797 Dog CDC42EP5 antibody; Canis familiaris CDC42EP5 antibody J9NWK4 100.0%
ARP52796 Dog CDC42EP5 antibody; Canis familiaris CDC42EP5 antibody J9NWK4 86.0%
ARP52796 Dusky titi monkey CDC42EP5 antibody; Callicebus moloch CDC42EP5 antibody B1MTX3 100.0%
ARP52797 Dusky titi monkey CDC42EP5 antibody; Callicebus moloch CDC42EP5 antibody B1MTX3 100.0%
ARP52796 Horse CDC42EP5 antibody; Equus caballus CDC42EP5 antibody F6QIU2 93.0%
ARP52796 Human CDC42EP5 antibody; Homo sapiens CDC42EP5 antibody Q6NZY7 100.0%
ARP52797 Human CDC42EP5 antibody; Homo sapiens CDC42EP5 antibody Q6NZY7 100.0%
ARP52797 Mouse CDC42EP5 antibody; Mus musculus CDC42EP5 antibody Q9Z0X0 100.0%
ARP52796 Mouse CDC42EP5 antibody; Mus musculus CDC42EP5 antibody D3Z5F0 100.0%
ARP52797 Mouse CDC42EP5 antibody; Mus musculus CDC42EP5 antibody D3Z5F0 100.0%
ARP52796 Mouse CDC42EP5 antibody; Mus musculus CDC42EP5 antibody Q9Z0X0 100.0%
ARP52797 Nine-banded armadillo CDC42EP5 antibody; Dasypus novemcinctus CDC42EP5 antibody C3PTA9 100.0%
ARP52796 Nine-banded armadillo CDC42EP5 antibody; Dasypus novemcinctus CDC42EP5 antibody C3PTA9 93.0%
ARP52796 Rat CDC42EP5 antibody; Rattus norvegicus CDC42EP5 antibody D3ZWQ6 93.0%
ARP52797 Rat CDC42EP5 antibody; Rattus norvegicus CDC42EP5 antibody D3ZWQ6 93.0%
ARP52796 Small-eared galago CDC42EP5 antibody; Otolemur garnettii CDC42EP5 antibody H0XMG7 100.0%
ARP52797 Small-eared galago CDC42EP5 antibody; Otolemur garnettii CDC42EP5 antibody H0XMG7 93.0%
ARP52796 Sumatran orangutan CDC42EP5 antibody; Pongo abelii CDC42EP5 antibody H2P035 100.0%
ARP52797 Sumatran orangutan CDC42EP5 antibody; Pongo abelii CDC42EP5 antibody H2P035 100.0%
ARP52796 Thirteen-lined ground squirrel CDC42EP5 antibody; Spermophilus tridecemlineatus CDC42EP5 antibody I3NB93 93.0%
ARP52797 Thirteen-lined ground squirrel CDC42EP5 antibody; Spermophilus tridecemlineatus CDC42EP5 antibody I3NB93 93.0%
ARP52796 White-tufted-ear marmoset CDC42EP5 antibody; Callithrix jacchus CDC42EP5 antibody B0VXJ7 100.0%
ARP52797 White-tufted-ear marmoset CDC42EP5 antibody; Callithrix jacchus CDC42EP5 antibody B0VXJ7 100.0%

Tissue & Cell Line Gene Expression Data