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Gene ID: 973 | CD79A Antibody Resource


CD79A Antibody Resource
Gene Full Name: 
CD79a molecule, immunoglobulin-associated alpha
Uniprot: 
P11912
Protein Name: 
B-cell antigen receptor complex-associated protein alpha chain
Nucleotide: 
NM_001783
Alias: 
IGA;MB-1;
Ensembl: 
ENSG00000105369
Location: 
19q13.2
HPRD: 
00203
NCBI Gene: 
973
MIM: 
112205

Summary: 
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Function: 
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Subcellular location: 
Cell membrane; Single-pass type I membrane protein. Note: Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts .
PTM: 
Disulfide bond;
Disease: 
Agammaglobulinemia 3, autosomal recessive (AGM3) [MIM:613501]: A primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life. Note: The disease is caused by mutations affecting the gene represented in this entry. Two different mutations, one at the splice donor site of intron 2 and the other at the splice acceptor site for exon 3, have been identified. Both mutations give rise to a truncated protein.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Monoclonal Antibody OASA02416 CD79A Antibody (OASA02416) Human ELISA, FC, IP 0.2mg $530 Details
Monoclonal Antibody OASA02417 CD79A Antibody (OASA02417) Human FC 20ug $135 Details
Monoclonal Antibody OASA02418 CD79A Antibody (OASA02418) Human IHC-AFF, FC, IHC-FFPE, WB 0.2mg $440 Details
Monoclonal Antibody OASA02419 CD79A Antibody (OASA02419) Human IHC-AFF, FC, IHC-FFPE 0.1mg $230 Details
Monoclonal Antibody OASA02420 CD79A Antibody (OASA02420) Human IHC-AFF, FC, IHC-FFPE, WB 1ml $415 Details
Monoclonal Antibody OASA02421 CD79A Antibody (OASA02421) Human IHC-AFF, FC, IHC-FFPE, WB 25ug $70 Details
Monoclonal Antibody OASA02422 CD79A Antibody (OASA02422) Human FC 0.1mg $495 Details
Monoclonal Antibody OASA02423 CD79A Antibody (OASA02423) Human FC 25ug $115 Details
Monoclonal Antibody OASA02424 MOUSE ANTI HUMAN CD79a:FITC Antibody (0.1mg) FC 0.1mg $355 Details
Monoclonal Antibody OASA02425 MOUSE ANTI HUMAN CD79a:FITC Antibody (25ug) FC 25ug $95 Details
Monoclonal Antibody OASA02426 CD79A Antibody (OASA02426) Human FC 100 Tests $495 Details
Monoclonal Antibody OASA02427 CD79A Antibody (OASA02427) Human FC 25 Tests $140 Details
Polyclonal Antibody ARP63188_P050 CD79A antibody - N-terminal region (ARP63188_P050) Human WB 50ug $289 Details
Polyclonal Antibody ARP63187_P050 CD79A Antibody - C-terminal region (ARP63187_P050) Polyclonal Human WB 50ug $289 Details
Monoclonal Antibody OAAB06862 CD79A antibody - C - terminal region (ascites) (OAAB06862) Mouse WB 0.1 ml $289 Details
Monoclonal Antibody OAAB06863 CD79A antibody - C - terminal region (OAAB06863) Mouse WB 400ul $289 Details
Polyclonal Antibody OAAB09351 CD79A antibody - C - terminal region (OAAB09351) Human WB 400ul $289 Details
Polyclonal Antibody OAAB11272 CD79A antibody - center region (OAAB11272) Human WB 400ul $289 Details
Polyclonal Antibody OAEC03390 CD79A Antibody (OAEC03390) Human WB, ELISA 100ug $229 Details
Polyclonal Antibody OAAF04671 CD79A Antibody (OAAF04671) Polyclonal Human WB, ELISA 100 ug $229 Details

Show all CD79A antibodies


Product Images
CD79A Antibody - C-terminal region (ARP63187_P050) in Human HT1080 cells using Western Blot

Sample Type: Human HT1080

CD79A antibody - N-terminal region (ARP63188_P050) in Human COLO205 cells using Western Blot

Sample Type: Human COLO205

CD79A antibody - C - terminal region (OAAB06862) in Mouse Spleen cells using Western Blot

Sample Type: Mouse Spleen

CD79A antibody - C - terminal region (OAAB06863) in Mouse Spleen cells using Western Blot

Sample Type: Mouse Spleen

CD79A antibody - C - terminal region (OAAB09351) in K562, CEM, Jurkat cells using Western Blot

Sample Type: K562, CEM, Jurkat

CD79A antibody - center region (OAAB11272) in CEM cells using Western Blot

Sample Type: CEM

CD79A Antibody (OAAF04671) in HuvEc cells using Western Blot

Sample Type: HuvEc

CD79A Antibody (OAEC03390) in HUVEC cells using Western Blot

Sample Type: HUVEC

CD79A Antibody (OASA02416) in human peripheral blood lymphocytes cells using Flow Cytometry

Sample Type: human peripheral blood lymphocytes

CD79A Antibody (OASA02416) in Ramos cells using Flow Cytometry

Sample Type: Ramos

CD79A Antibody (OASA02416) in Ramos cells using Flow Cytometry

Sample Type: Ramos

CD79A Antibody (OASA02417) in human peripheral blood lymphocytes cells using Flow Cytometry

Sample Type: human peripheral blood lymphocytes

CD79A Antibody (OASA02417) in Ramos cells using Flow Cytometry

Sample Type: Ramos

CD79A Antibody (OASA02417) in Ramos cells using Flow Cytometry

Sample Type: Ramos

CD79A Antibody (OASA02418) in Human tonsil cells using Immunohistochemistry

Sample Type: Human tonsil

CD79A Antibody (OASA02419) in Human tonsil cells using Immunohistochemistry

Sample Type: Human tonsil

CD79A Antibody (OASA02420) in Human tonsil cells using Immunohistochemistry

Sample Type: Human tonsil

CD79A Antibody (OASA02421) in Human tonsil cells using Immunohistochemistry

Sample Type: Human tonsil

CD79A Antibody (OASA02422) in human peripheral blood lymphocytes cells using Flow Cytometry

Sample Type: human peripheral blood lymphocytes

CD79A Antibody (OASA02422) in Ramos cells using Flow Cytometry

Sample Type: Ramos

CD79A Antibody (OASA02422) in Ramos cells using Flow Cytometry

Sample Type: Ramos

CD79A Antibody (OASA02423) in human peripheral blood lymphocytes cells using Flow Cytometry

Sample Type: human peripheral blood lymphocytes

CD79A Antibody (OASA02423) in Ramos cells using Flow Cytometry

Sample Type: Ramos

CD79A Antibody (OASA02423) in Ramos cells using Flow Cytometry

Sample Type: Ramos

CD79A Antibody (OASA02426) in human tonsil cells using Flow Cytometry

Sample Type: human tonsil

CD79A Antibody (OASA02427) in human tonsil cells using Flow Cytometry

Sample Type: human tonsil


CD79A Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP63187 Chimpanzee CD79A antibody; Pan troglodytes CD79A antibody H2QGF1 100.0%
ARP63188 Chimpanzee CD79A antibody; Pan troglodytes CD79A antibody H2QGF1 100.0%
ARP63188 Human CD79A antibody; Homo sapiens CD79A antibody M0QX61 100.0%
ARP63187 Human CD79A antibody; Homo sapiens CD79A antibody P11912-2 100.0%
ARP63187 Human CD79A antibody; Homo sapiens CD79A antibody P11912 100.0%
ARP63188 Human CD79A antibody; Homo sapiens CD79A antibody P11912 100.0%
ARP63187 Northern white-cheeked gibbon CD79A antibody; Nomascus leucogenys CD79A antibody G1RT24 100.0%
ARP63188 Northern white-cheeked gibbon CD79A antibody; Nomascus leucogenys CD79A antibody G1RT24 79.0%
ARP63187 Rhesus macaque CD79A antibody; Macaca mulatta CD79A antibody H9ZFT2 100.0%
ARP63187 Rhesus macaque CD79A antibody; Macaca mulatta CD79A antibody H9ZFT3 100.0%
ARP63188 Rhesus macaque CD79A antibody; Macaca mulatta CD79A antibody H9ZFT2 79.0%
ARP63187 Sumatran orangutan CD79A antibody; Pongo abelii CD79A antibody H2NYZ1 100.0%
ARP63188 Sumatran orangutan CD79A antibody; Pongo abelii CD79A antibody H2NYZ1 100.0%
ARP63187 Sumatran orangutan CD79A antibody; Pongo abelii CD79A antibody K7EV82 100.0%
ARP63188 Sumatran orangutan CD79A antibody; Pongo abelii CD79A antibody K7EV82 100.0%
ARP63187 White-tufted-ear marmoset CD79A antibody; Callithrix jacchus CD79A antibody F7AEC1 100.0%
ARP63188 White-tufted-ear marmoset CD79A antibody; Callithrix jacchus CD79A antibody F7AEC1 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas205049_s_at721_B_lymphoblasts698.450141.630Details
BioGPS Gene Atlas205049_s_atAdipocyte8.950141.630Details
BioGPS Gene Atlas205049_s_atAdrenalCortex13.450141.630Details
BioGPS Gene Atlas205049_s_atAdrenalgland10.550141.630Details
BioGPS Gene Atlas205049_s_atAmygdala8.850141.630Details
BioGPS Gene Atlas205049_s_atAppendix12.450141.630Details
BioGPS Gene Atlas205049_s_atAtrioventricularNode12.600141.630Details
BioGPS Gene Atlas205049_s_atBDCA4+_DentriticCells345.500141.630Details
BioGPS Gene Atlas205049_s_atBonemarrow104.100141.630Details
BioGPS Gene Atlas205049_s_atBronchialEpithelialCells6.850141.630Details
BioGPS Gene Atlas205049_s_atCD105+_Endothelial14.050141.630Details
BioGPS Gene Atlas205049_s_atCD14+_Monocytes9.100141.630Details
BioGPS Gene Atlas205049_s_atCD19+_BCells(neg._sel.)3383.100141.630Details
BioGPS Gene Atlas205049_s_atCD33+_Myeloid10.500141.630Details
BioGPS Gene Atlas205049_s_atCD34+74.750141.630Details
BioGPS Gene Atlas205049_s_atCD4+_Tcells16.450141.630Details
BioGPS Gene Atlas205049_s_atCD56+_NKCells71.250141.630Details
BioGPS Gene Atlas205049_s_atCD71+_EarlyErythroid16.250141.630Details
BioGPS Gene Atlas205049_s_atCD8+_Tcells13.400141.630Details
BioGPS Gene Atlas205049_s_atCardiacMyocytes11.150141.630Details
BioGPS Gene Atlas205049_s_atCaudatenucleus8.800141.630Details
BioGPS Gene Atlas205049_s_atCerebellum7.800141.630Details
BioGPS Gene Atlas205049_s_atCerebellumPeduncles11.850141.630Details
BioGPS Gene Atlas205049_s_atCiliaryGanglion5.600141.630Details
BioGPS Gene Atlas205049_s_atCingulateCortex17.850141.630Details
BioGPS Gene Atlas205049_s_atColorectaladenocarcinoma8.400141.630Details
BioGPS Gene Atlas205049_s_atDorsalRootGanglion8.350141.630Details
BioGPS Gene Atlas205049_s_atFetalThyroid17.250141.630Details
BioGPS Gene Atlas205049_s_atFetalbrain7.950141.630Details
BioGPS Gene Atlas205049_s_atFetalliver8.250141.630Details
BioGPS Gene Atlas205049_s_atFetallung7.850141.630Details
BioGPS Gene Atlas205049_s_atGlobusPallidus6.250141.630Details
BioGPS Gene Atlas205049_s_atHeart127.600141.630Details
BioGPS Gene Atlas205049_s_atHypothalamus10.200141.630Details
BioGPS Gene Atlas205049_s_atKidney12.100141.630Details
BioGPS Gene Atlas205049_s_atLeukemia_chronicMyelogenousK-5628.000141.630Details
BioGPS Gene Atlas205049_s_atLeukemia_promyelocytic-HL-60437.100141.630Details
BioGPS Gene Atlas205049_s_atLeukemialymphoblastic(MOLT-4)7.350141.630Details
BioGPS Gene Atlas205049_s_atLiver15.450141.630Details
BioGPS Gene Atlas205049_s_atLung10.050141.630Details
BioGPS Gene Atlas205049_s_atLymphnode415.000141.630Details
BioGPS Gene Atlas205049_s_atLymphoma_burkitts(Daudi)1444.550141.630Details
BioGPS Gene Atlas205049_s_atLymphoma_burkitts(Raji)3281.850141.630Details
BioGPS Gene Atlas205049_s_atMedullaOblongata11.150141.630Details
BioGPS Gene Atlas205049_s_atOccipitalLobe10.500141.630Details
BioGPS Gene Atlas205049_s_atOlfactoryBulb7.100141.630Details
BioGPS Gene Atlas205049_s_atOvary5.950141.630Details
BioGPS Gene Atlas205049_s_atPancreas18.950141.630Details
BioGPS Gene Atlas205049_s_atPancreaticIslet11.650141.630Details
BioGPS Gene Atlas205049_s_atParietalLobe9.850141.630Details
BioGPS Gene Atlas205049_s_atPituitary13.550141.630Details
BioGPS Gene Atlas205049_s_atPlacenta10.850141.630Details
BioGPS Gene Atlas205049_s_atPons12.400141.630Details
BioGPS Gene Atlas205049_s_atPrefrontalCortex9.300141.630Details
BioGPS Gene Atlas205049_s_atProstate9.900141.630Details
BioGPS Gene Atlas205049_s_atSalivarygland36.200141.630Details
BioGPS Gene Atlas205049_s_atSkeletalMuscle35.600141.630Details
BioGPS Gene Atlas205049_s_atSkin6.200141.630Details
BioGPS Gene Atlas205049_s_atSmoothMuscle9.500141.630Details
BioGPS Gene Atlas205049_s_atSpinalcord14.400141.630Details
BioGPS Gene Atlas205049_s_atSubthalamicNucleus19.150141.630Details
BioGPS Gene Atlas205049_s_atSuperiorCervicalGanglion33.850141.630Details
BioGPS Gene Atlas205049_s_atTemporalLobe14.600141.630Details
BioGPS Gene Atlas205049_s_atTestis8.350141.630Details
BioGPS Gene Atlas205049_s_atTestisGermCell7.950141.630Details
BioGPS Gene Atlas205049_s_atTestisIntersitial8.400141.630Details
BioGPS Gene Atlas205049_s_atTestisLeydigCell11.800141.630Details
BioGPS Gene Atlas205049_s_atTestisSeminiferousTubule10.550141.630Details
BioGPS Gene Atlas205049_s_atThalamus11.150141.630Details
BioGPS Gene Atlas205049_s_atThymus141.450141.630Details
BioGPS Gene Atlas205049_s_atThyroid16.300141.630Details
BioGPS Gene Atlas205049_s_atTongue8.000141.630Details
BioGPS Gene Atlas205049_s_atTonsil913.700141.630Details
BioGPS Gene Atlas205049_s_atTrachea81.850141.630Details
BioGPS Gene Atlas205049_s_atTrigeminalGanglion7.850141.630Details
BioGPS Gene Atlas205049_s_atUterus6.300141.630Details
BioGPS Gene Atlas205049_s_atUterusCorpus19.550141.630Details
BioGPS Gene Atlas205049_s_atWholeBlood59.250141.630Details
BioGPS Gene Atlas205049_s_atWholebrain6.700141.630Details
BioGPS Gene Atlas205049_s_atcolon17.500141.630Details
BioGPS Gene Atlas205049_s_atpineal_day10.720141.630Details
BioGPS Gene Atlas205049_s_atpineal_night11.800141.630Details
BioGPS Gene Atlas205049_s_atretina12.100141.630Details
BioGPS Gene Atlas205049_s_atsmall_intestine18.700141.630Details
BioGPS NCI60205049_s_at7863.78056.690Details
BioGPS NCI60205049_s_atA1723.57656.690Details
BioGPS NCI60205049_s_atA2043.66556.690Details
BioGPS NCI60205049_s_atA3613.72056.690Details
BioGPS NCI60205049_s_atA4983.68556.690Details
BioGPS NCI60205049_s_atA5493.75156.690Details
BioGPS NCI60205049_s_atACC33.79356.690Details
BioGPS NCI60205049_s_atACHN3.61856.690Details
BioGPS NCI60205049_s_atALVA314.43356.690Details
BioGPS NCI60205049_s_atCAKI13.78456.690Details
BioGPS NCI60205049_s_atCCRT CEM15.55756.690Details
BioGPS NCI60205049_s_atCOLO2053.68856.690Details
BioGPS NCI60205049_s_atDLD13.63456.690Details
BioGPS NCI60205049_s_atDU1453.56456.690Details
BioGPS NCI60205049_s_atEKVX3.59556.690Details
BioGPS NCI60205049_s_atGM1333.78356.690Details
BioGPS NCI60205049_s_atGM16003.77656.690Details
BioGPS NCI60205049_s_atGM23133.75156.690Details
BioGPS NCI60205049_s_atGM23453.71656.690Details
BioGPS NCI60205049_s_atGM24933.77656.690Details
BioGPS NCI60205049_s_atGM974.03456.690Details
BioGPS NCI60205049_s_atHCC29983.56556.690Details
BioGPS NCI60205049_s_atHCT1163.77156.690Details
BioGPS NCI60205049_s_atHCT153.53556.690Details
BioGPS NCI60205049_s_atHEK 293 T-rex3.91456.690Details
BioGPS NCI60205049_s_atHEK 293T3.69256.690Details
BioGPS NCI60205049_s_atHEK2933.78756.690Details
BioGPS NCI60205049_s_atHELA3.55556.690Details
BioGPS NCI60205049_s_atHEPG23.69956.690Details
BioGPS NCI60205049_s_atHL601136.03356.690Details
BioGPS NCI60205049_s_atHOP623.73356.690Details
BioGPS NCI60205049_s_atHOP923.67456.690Details
BioGPS NCI60205049_s_atHS578T3.69956.690Details
BioGPS NCI60205049_s_atHSG3.64556.690Details
BioGPS NCI60205049_s_atHT10803.67856.690Details
BioGPS NCI60205049_s_atHT293.82756.690Details
BioGPS NCI60205049_s_atIGROV13.68556.690Details
BioGPS NCI60205049_s_atIOSE803.72356.690Details
BioGPS NCI60205049_s_atJURKAT6.65256.690Details
BioGPS NCI60205049_s_atK5624.38156.690Details
BioGPS NCI60205049_s_atKM123.81556.690Details
BioGPS NCI60205049_s_atLN183.55656.690Details
BioGPS NCI60205049_s_atLNCAP3.70156.690Details
BioGPS NCI60205049_s_atLOX IMVI3.68156.690Details
BioGPS NCI60205049_s_atM143.64756.690Details
BioGPS NCI60205049_s_atMALME 3M4.11856.690Details
BioGPS NCI60205049_s_atMCF73.58556.690Details
BioGPS NCI60205049_s_atMD MB2313.79356.690Details
BioGPS NCI60205049_s_atMDA MB4353.80556.690Details
BioGPS NCI60205049_s_atMOLT45.35956.690Details
BioGPS NCI60205049_s_atNCI 4603.76956.690Details
BioGPS NCI60205049_s_atNCI H2263.77156.690Details
BioGPS NCI60205049_s_atNCI H233.70956.690Details
BioGPS NCI60205049_s_atNCI H322M3.71656.690Details
BioGPS NCI60205049_s_atNCVADR RES3.64756.690Details
BioGPS NCI60205049_s_atOVCAR33.78556.690Details
BioGPS NCI60205049_s_atOVCAR43.69456.690Details
BioGPS NCI60205049_s_atOVCAR53.63956.690Details
BioGPS NCI60205049_s_atOVCAR83.58756.690Details
BioGPS NCI60205049_s_atPANC13.88756.690Details
BioGPS NCI60205049_s_atRL71369.77556.690Details
BioGPS NCI60205049_s_atRPMI 82263.91956.690Details
BioGPS NCI60205049_s_atRS118462074.05356.690Details
BioGPS NCI60205049_s_atRXF3933.70956.690Details
BioGPS NCI60205049_s_atSAOS23.73556.690Details
BioGPS NCI60205049_s_atSF2683.68656.690Details
BioGPS NCI60205049_s_atSF2953.88856.690Details
BioGPS NCI60205049_s_atSF5393.61556.690Details
BioGPS NCI60205049_s_atSHSYSY+RA3.60956.690Details
BioGPS NCI60205049_s_atSHSYSY-RA3.68956.690Details
BioGPS NCI60205049_s_atSKMEL23.66656.690Details
BioGPS NCI60205049_s_atSKMEL283.69856.690Details
BioGPS NCI60205049_s_atSKMEL53.92456.690Details
BioGPS NCI60205049_s_atSKOV33.74956.690Details
BioGPS NCI60205049_s_atSN12C3.65856.690Details
BioGPS NCI60205049_s_atSNB193.54156.690Details
BioGPS NCI60205049_s_atSNB753.67356.690Details
BioGPS NCI60205049_s_atSR4.23256.690Details
BioGPS NCI60205049_s_atSW6203.84956.690Details
BioGPS NCI60205049_s_atT243.74356.690Details
BioGPS NCI60205049_s_atT3M43.90256.690Details
BioGPS NCI60205049_s_atTK103.69356.690Details
BioGPS NCI60205049_s_atU1183.67056.690Details
BioGPS NCI60205049_s_atU1383.54256.690Details
BioGPS NCI60205049_s_atU20S4.32456.690Details
BioGPS NCI60205049_s_atU2513.69356.690Details
BioGPS NCI60205049_s_atU873.61956.690Details
BioGPS NCI60205049_s_atUACC2573.67656.690Details
BioGPS NCI60205049_s_atUACC623.73456.690Details
BioGPS NCI60205049_s_atUO313.59856.690Details
BioGPS NCI60205049_s_atZR75_13.77056.690Details
BioGPS NCI60205049_s_atastrocytes4.22256.690Details
BioGPS NCI60205049_s_athuh-73.78056.690Details