Search Antibody, Protein, and ELISA Kit Solutions


Gene ID: 972 | CD74 Antibody Resource


CD74 Antibody Resource
Gene Full Name: 
CD74 molecule, major histocompatibility complex, class II invariant chain
Uniprot: 
P04233
Protein Name: 
HLA class II histocompatibility antigen gamma chain
Nucleotide: 
XM_005268545
Alias: 
II;DHLAG;HLADG;Ia-GAMMA;
Ensembl: 
ENSG00000019582
Location: 
5q32
HPRD: 
00825
NCBI Gene: 
972
MIM: 
142790

Summary: 
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Function: 
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Subcellular location: 
Cell membrane; Single-pass type II membrane protein Potential. Endoplasmic reticulum membrane. Golgi apparatus › trans-Golgi network. Endosome. Lysosome. Note: Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane.
PTM: 
Disulfide bond;
Disease: 
A chromosomal aberration involving CD74 is found in a non-small cell lung tumor. Results in the formation of a CD74-ROS1 chimeric protein.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Monoclonal Antibody OASA02409 CD74 Antibody (OASA02409) Human FC, IP 0.2mg $425 Details
Monoclonal Antibody OASA02410 CD74 Antibody (OASA02410) Human FC, IP 25ug $90 Details
Monoclonal Antibody OASA02411 CD74 Antibody (OASA02411) Human IHC-AFF, FC, IP 0.2mg $415 Details
Monoclonal Antibody OASA02412 CD74 Antibody (OASA02412) Human IHC-AFF, FC, IP 25ug $75 Details
Monoclonal Antibody OASA02413 CD74 Antibody (OASA02413) Human FC 0.1mg $365 Details
Monoclonal Antibody OASA02414 CD74 Antibody (OASA02414) Human FC 25ug $105 Details
Polyclonal Antibody ARP63452_P050 CD74 Antibody (ARP63452_P050) Polyclonal Human Not tested 50 ug $125 Details
Polyclonal Antibody ARP63453_P050 CD74 Antibody (ARP63453_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Pig, Rabbit Not tested 50 ug $125 Details
Polyclonal Antibody OAGA00850 CD74 antibody (OAGA00850) Polyclonal Human, Mouse, Rat IHC (Formalin-fixed paraffin-embedded sections), WB 100 ul $340 Details
Monoclonal Antibody OAED00056 Anti-CD74 (PIN.1) Antibody (OAED00056) Human FC, ICC, IP, WB 25 ug $150 Details

Show all CD74 antibodies


Product Images
CD74 Antibody (OASA02409) in human peripheral blood lymphocytes cells using Flow Cytometry

Sample Type: human peripheral blood lymphocytes

CD74 Antibody (OASA02410) in human peripheral blood lymphocytes cells using Flow Cytometry

Sample Type: human peripheral blood lymphocytes


CD74 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP63453 Pan troglodytes verus CD74 antibody A5A6L4 100.0%
ARP63452 Pan troglodytes verus CD74 antibody A5A6L4 93.0%
ARP63453 Bovine CD74 antibody; Bos taurus CD74 antibody Q29630 93.0%
ARP63453 Cat CD74 antibody; Felis catus CD74 antibody M3VXS2 93.0%
ARP63453 Chimpanzee CD74 antibody; Pan troglodytes CD74 antibody H2QRT2 100.0%
ARP63453 Chimpanzee CD74 antibody; Pan troglodytes CD74 antibody H2R586 100.0%
ARP63452 Chimpanzee CD74 antibody; Pan troglodytes CD74 antibody H2R586 93.0%
ARP63452 Chimpanzee CD74 antibody; Pan troglodytes CD74 antibody H2QRT2 93.0%
ARP63453 Dog CD74 antibody; Canis familiaris CD74 antibody E2RF90 100.0%
ARP63453 European domestic ferret CD74 antibody; Mustela putorius furo CD74 antibody M3YQS4 93.0%
ARP63453 Giant panda CD74 antibody; Ailuropoda melanoleuca CD74 antibody G1LDD9 100.0%
ARP63453 Horse CD74 antibody; Equus caballus CD74 antibody F6TGS3 86.0%
ARP63453 Human CD74 antibody; Homo sapiens CD74 antibody E7EQJ3 100.0%
ARP63453 Human CD74 antibody; Homo sapiens CD74 antibody E7ESL3 100.0%
ARP63452 Human CD74 antibody; Homo sapiens CD74 antibody P04233-2 100.0%
ARP63453 Human CD74 antibody; Homo sapiens CD74 antibody P04233-2 100.0%
ARP63453 Human CD74 antibody; Homo sapiens CD74 antibody P04233-3 100.0%
ARP63452 Human CD74 antibody; Homo sapiens CD74 antibody P04233 100.0%
ARP63453 Human CD74 antibody; Homo sapiens CD74 antibody P04233 100.0%
ARP63452 Human CD74 antibody; Homo sapiens CD74 antibody H0YBZ2 100.0%
ARP63453 Human CD74 antibody; Homo sapiens CD74 antibody H0YBZ2 100.0%
ARP63453 Human CD74 antibody; Homo sapiens CD74 antibody H0YBZ8 100.0%
ARP63453 Pig CD74 antibody; Sus scrofa CD74 antibody Q764N1 100.0%
ARP63453 Rabbit CD74 antibody; Oryctolagus cuniculus CD74 antibody G1SKK3 86.0%
ARP44083 Rat CD74 antibody; Rattus norvegicus CD74 antibody B5DFE3 100.0%
ARP63452 Rhesus macaque CD74 antibody; Macaca mulatta CD74 antibody I0FWR3 93.0%
ARP63453 Rhesus macaque CD74 antibody; Macaca mulatta CD74 antibody I0FWR3 93.0%
ARP63453 Rhesus macaque CD74 antibody; Macaca mulatta CD74 antibody I0FWR4 93.0%
ARP63452 Rhesus macaque CD74 antibody; Macaca mulatta CD74 antibody I0FWR4 90.0%
ARP63452 Rhesus macaque CD74 antibody; Macaca mulatta CD74 antibody F7E9S4 90.0%
ARP63453 Rhesus macaque CD74 antibody; Macaca mulatta CD74 antibody F7E9S4 86.0%
ARP63453 Small-eared galago CD74 antibody; Otolemur garnettii CD74 antibody H0WQB3 79.0%
ARP63453 White-tufted-ear marmoset CD74 antibody; Callithrix jacchus CD74 antibody F6V5T6 100.0%
ARP63453 White-tufted-ear marmoset CD74 antibody; Callithrix jacchus CD74 antibody F7ENE3 100.0%
ARP63453 White-tufted-ear marmoset CD74 antibody; Callithrix jacchus CD74 antibody F7ENE8 100.0%
ARP63453 White-tufted-ear marmoset CD74 antibody; Callithrix jacchus CD74 antibody F7ENF4 100.0%
ARP63453 White-tufted-ear marmoset CD74 antibody; Callithrix jacchus CD74 antibody F7ENM4 100.0%
ARP63452 White-tufted-ear marmoset CD74 antibody; Callithrix jacchus CD74 antibody F6VER1 93.0%
ARP63452 White-tufted-ear marmoset CD74 antibody; Callithrix jacchus CD74 antibody F7ENE8 93.0%
ARP63452 White-tufted-ear marmoset CD74 antibody; Callithrix jacchus CD74 antibody F6V5T6 90.0%
ARP63452 White-tufted-ear marmoset CD74 antibody; Callithrix jacchus CD74 antibody F7ENE3 90.0%
ARP63452 White-tufted-ear marmoset CD74 antibody; Callithrix jacchus CD74 antibody F7ENM4 90.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas209619_at721_B_lymphoblasts10299.2501728.980Details
BioGPS Gene Atlas209619_atAdipocyte11.8001728.980Details
BioGPS Gene Atlas209619_atAdrenalCortex581.3001728.980Details
BioGPS Gene Atlas209619_atAdrenalgland1849.3001728.980Details
BioGPS Gene Atlas209619_atAmygdala574.9001728.980Details
BioGPS Gene Atlas209619_atAppendix346.8501728.980Details
BioGPS Gene Atlas209619_atAtrioventricularNode202.2501728.980Details
BioGPS Gene Atlas209619_atBDCA4+_DentriticCells8240.8501728.980Details
BioGPS Gene Atlas209619_atBonemarrow1196.2501728.980Details
BioGPS Gene Atlas209619_atBronchialEpithelialCells12.0501728.980Details
BioGPS Gene Atlas209619_atCD105+_Endothelial775.7501728.980Details
BioGPS Gene Atlas209619_atCD14+_Monocytes8259.8001728.980Details
BioGPS Gene Atlas209619_atCD19+_BCells(neg._sel.)10015.7001728.980Details
BioGPS Gene Atlas209619_atCD33+_Myeloid5150.8001728.980Details
BioGPS Gene Atlas209619_atCD34+2381.4001728.980Details
BioGPS Gene Atlas209619_atCD4+_Tcells708.2501728.980Details
BioGPS Gene Atlas209619_atCD56+_NKCells1993.0001728.980Details
BioGPS Gene Atlas209619_atCD71+_EarlyErythroid111.3001728.980Details
BioGPS Gene Atlas209619_atCD8+_Tcells548.5001728.980Details
BioGPS Gene Atlas209619_atCardiacMyocytes13.4001728.980Details
BioGPS Gene Atlas209619_atCaudatenucleus576.2001728.980Details
BioGPS Gene Atlas209619_atCerebellum153.5001728.980Details
BioGPS Gene Atlas209619_atCerebellumPeduncles236.9001728.980Details
BioGPS Gene Atlas209619_atCiliaryGanglion585.0001728.980Details
BioGPS Gene Atlas209619_atCingulateCortex81.2501728.980Details
BioGPS Gene Atlas209619_atColorectaladenocarcinoma72.3001728.980Details
BioGPS Gene Atlas209619_atDorsalRootGanglion1101.6001728.980Details
BioGPS Gene Atlas209619_atFetalThyroid276.3001728.980Details
BioGPS Gene Atlas209619_atFetalbrain21.6001728.980Details
BioGPS Gene Atlas209619_atFetalliver204.3501728.980Details
BioGPS Gene Atlas209619_atFetallung779.8501728.980Details
BioGPS Gene Atlas209619_atGlobusPallidus123.9001728.980Details
BioGPS Gene Atlas209619_atHeart3130.3501728.980Details
BioGPS Gene Atlas209619_atHypothalamus761.5501728.980Details
BioGPS Gene Atlas209619_atKidney1320.3501728.980Details
BioGPS Gene Atlas209619_atLeukemia_chronicMyelogenousK-56211.6501728.980Details
BioGPS Gene Atlas209619_atLeukemia_promyelocytic-HL-605201.0001728.980Details
BioGPS Gene Atlas209619_atLeukemialymphoblastic(MOLT-4)14.0001728.980Details
BioGPS Gene Atlas209619_atLiver1178.3001728.980Details
BioGPS Gene Atlas209619_atLung8790.1001728.980Details
BioGPS Gene Atlas209619_atLymphnode4500.3001728.980Details
BioGPS Gene Atlas209619_atLymphoma_burkitts(Daudi)6050.1001728.980Details
BioGPS Gene Atlas209619_atLymphoma_burkitts(Raji)16134.6001728.980Details
BioGPS Gene Atlas209619_atMedullaOblongata157.4501728.980Details
BioGPS Gene Atlas209619_atOccipitalLobe330.1501728.980Details
BioGPS Gene Atlas209619_atOlfactoryBulb1832.5001728.980Details
BioGPS Gene Atlas209619_atOvary433.8501728.980Details
BioGPS Gene Atlas209619_atPancreas155.7501728.980Details
BioGPS Gene Atlas209619_atPancreaticIslet698.8001728.980Details
BioGPS Gene Atlas209619_atParietalLobe152.1001728.980Details
BioGPS Gene Atlas209619_atPituitary974.7001728.980Details
BioGPS Gene Atlas209619_atPlacenta806.3001728.980Details
BioGPS Gene Atlas209619_atPons245.2001728.980Details
BioGPS Gene Atlas209619_atPrefrontalCortex474.5501728.980Details
BioGPS Gene Atlas209619_atProstate914.7501728.980Details
BioGPS Gene Atlas209619_atSalivarygland1967.6001728.980Details
BioGPS Gene Atlas209619_atSkeletalMuscle122.6501728.980Details
BioGPS Gene Atlas209619_atSkin462.0001728.980Details
BioGPS Gene Atlas209619_atSmoothMuscle10.1501728.980Details
BioGPS Gene Atlas209619_atSpinalcord2798.4501728.980Details
BioGPS Gene Atlas209619_atSubthalamicNucleus159.8001728.980Details
BioGPS Gene Atlas209619_atSuperiorCervicalGanglion161.7501728.980Details
BioGPS Gene Atlas209619_atTemporalLobe148.8501728.980Details
BioGPS Gene Atlas209619_atTestis172.7501728.980Details
BioGPS Gene Atlas209619_atTestisGermCell221.5001728.980Details
BioGPS Gene Atlas209619_atTestisIntersitial122.9001728.980Details
BioGPS Gene Atlas209619_atTestisLeydigCell153.1501728.980Details
BioGPS Gene Atlas209619_atTestisSeminiferousTubule108.5001728.980Details
BioGPS Gene Atlas209619_atThalamus710.8001728.980Details
BioGPS Gene Atlas209619_atThymus3302.0501728.980Details
BioGPS Gene Atlas209619_atThyroid1984.1501728.980Details
BioGPS Gene Atlas209619_atTongue443.6001728.980Details
BioGPS Gene Atlas209619_atTonsil5548.1501728.980Details
BioGPS Gene Atlas209619_atTrachea2419.7001728.980Details
BioGPS Gene Atlas209619_atTrigeminalGanglion406.3001728.980Details
BioGPS Gene Atlas209619_atUterus699.1001728.980Details
BioGPS Gene Atlas209619_atUterusCorpus297.3001728.980Details
BioGPS Gene Atlas209619_atWholeBlood4718.6501728.980Details
BioGPS Gene Atlas209619_atWholebrain138.2501728.980Details
BioGPS Gene Atlas209619_atcolon1122.7501728.980Details
BioGPS Gene Atlas209619_atpineal_day589.4201728.980Details
BioGPS Gene Atlas209619_atpineal_night642.4601728.980Details
BioGPS Gene Atlas209619_atretina3010.8501728.980Details
BioGPS Gene Atlas209619_atsmall_intestine2893.9001728.980Details
BioGPS NCI60209619_at7868.665581.150Details
BioGPS NCI60209619_atA1724.699581.150Details
BioGPS NCI60209619_atA2045.570581.150Details
BioGPS NCI60209619_atA3615.647581.150Details
BioGPS NCI60209619_atA4985.623581.150Details
BioGPS NCI60209619_atA5495.676581.150Details
BioGPS NCI60209619_atACC319.263581.150Details
BioGPS NCI60209619_atACHN321.567581.150Details
BioGPS NCI60209619_atALVA315.737581.150Details
BioGPS NCI60209619_atCAKI1116.973581.150Details
BioGPS NCI60209619_atCCRT CEM34.165581.150Details
BioGPS NCI60209619_atCOLO2055.607581.150Details
BioGPS NCI60209619_atDLD14.833581.150Details
BioGPS NCI60209619_atDU14528.878581.150Details
BioGPS NCI60209619_atEKVX4.723581.150Details
BioGPS NCI60209619_atGM1335.523581.150Details
BioGPS NCI60209619_atGM16005.782581.150Details
BioGPS NCI60209619_atGM2313203.292581.150Details
BioGPS NCI60209619_atGM23455.631581.150Details
BioGPS NCI60209619_atGM24935.737581.150Details
BioGPS NCI60209619_atGM975.967581.150Details
BioGPS NCI60209619_atHCC29984.467581.150Details
BioGPS NCI60209619_atHCT1165.388581.150Details
BioGPS NCI60209619_atHCT154.657581.150Details
BioGPS NCI60209619_atHEK 293 T-rex5.669581.150Details
BioGPS NCI60209619_atHEK 293T5.151581.150Details
BioGPS NCI60209619_atHEK2934.858581.150Details
BioGPS NCI60209619_atHELA4.618581.150Details
BioGPS NCI60209619_atHEPG2359.424581.150Details
BioGPS NCI60209619_atHL6014119.989581.150Details
BioGPS NCI60209619_atHOP62864.220581.150Details
BioGPS NCI60209619_atHOP92168.121581.150Details
BioGPS NCI60209619_atHS578T5.476581.150Details
BioGPS NCI60209619_atHSG5.530581.150Details
BioGPS NCI60209619_atHT10805.621581.150Details
BioGPS NCI60209619_atHT295.815581.150Details
BioGPS NCI60209619_atIGROV15.562581.150Details
BioGPS NCI60209619_atIOSE804.982581.150Details
BioGPS NCI60209619_atJURKAT5.599581.150Details
BioGPS NCI60209619_atK56214.671581.150Details
BioGPS NCI60209619_atKM1242.201581.150Details
BioGPS NCI60209619_atLN184.134581.150Details
BioGPS NCI60209619_atLNCAP7.132581.150Details
BioGPS NCI60209619_atLOX IMVI5.580581.150Details
BioGPS NCI60209619_atM142520.715581.150Details
BioGPS NCI60209619_atMALME 3M35.853581.150Details
BioGPS NCI60209619_atMCF74.845581.150Details
BioGPS NCI60209619_atMD MB231165.113581.150Details
BioGPS NCI60209619_atMDA MB43561.887581.150Details
BioGPS NCI60209619_atMOLT45.691581.150Details
BioGPS NCI60209619_atNCI 4605.699581.150Details
BioGPS NCI60209619_atNCI H2265.428581.150Details
BioGPS NCI60209619_atNCI H235.633581.150Details
BioGPS NCI60209619_atNCI H322M5.628581.150Details
BioGPS NCI60209619_atNCVADR RES88.865581.150Details
BioGPS NCI60209619_atOVCAR35.764581.150Details
BioGPS NCI60209619_atOVCAR4253.455581.150Details
BioGPS NCI60209619_atOVCAR5855.762581.150Details
BioGPS NCI60209619_atOVCAR86.031581.150Details
BioGPS NCI60209619_atPANC15.646581.150Details
BioGPS NCI60209619_atRL713332.516581.150Details
BioGPS NCI60209619_atRPMI 82261801.062581.150Details
BioGPS NCI60209619_atRS118465056.729581.150Details
BioGPS NCI60209619_atRXF3935.379581.150Details
BioGPS NCI60209619_atSAOS25.179581.150Details
BioGPS NCI60209619_atSF2685.106581.150Details
BioGPS NCI60209619_atSF2955.559581.150Details
BioGPS NCI60209619_atSF5395.430581.150Details
BioGPS NCI60209619_atSHSYSY+RA5.502581.150Details
BioGPS NCI60209619_atSHSYSY-RA5.567581.150Details
BioGPS NCI60209619_atSKMEL21116.490581.150Details
BioGPS NCI60209619_atSKMEL28484.065581.150Details
BioGPS NCI60209619_atSKMEL5437.520581.150Details
BioGPS NCI60209619_atSKOV35.674581.150Details
BioGPS NCI60209619_atSN12C14.955581.150Details
BioGPS NCI60209619_atSNB195.431581.150Details
BioGPS NCI60209619_atSNB7514.198581.150Details
BioGPS NCI60209619_atSR3004.362581.150Details
BioGPS NCI60209619_atSW6205.588581.150Details
BioGPS NCI60209619_atT247.895581.150Details
BioGPS NCI60209619_atT3M45.727581.150Details
BioGPS NCI60209619_atTK10277.177581.150Details
BioGPS NCI60209619_atU118251.117581.150Details
BioGPS NCI60209619_atU1385.449581.150Details
BioGPS NCI60209619_atU20S5.566581.150Details
BioGPS NCI60209619_atU2515.567581.150Details
BioGPS NCI60209619_atU87504.474581.150Details
BioGPS NCI60209619_atUACC2576.810581.150Details
BioGPS NCI60209619_atUACC6293.744581.150Details
BioGPS NCI60209619_atUO31208.525581.150Details
BioGPS NCI60209619_atZR75_1215.317581.150Details
BioGPS NCI60209619_atastrocytes210.635581.150Details
BioGPS NCI60209619_athuh-75.678581.150Details